Erschienen in:
28.08.2019 | Controversies in Colon and Rectal Surgery
How to find a meta-analysis you can trust
verfasst von:
R. L. Nelson
Erschienen in:
Techniques in Coloproctology
|
Ausgabe 9/2019
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Excerpt
I first read of meta-analysis in 1981, in a paper by Baum et al. in the New England Journal [
1]. It described a meta-analysis of 17 randomized trials assessing the value of prophylactic antibiotics in colorectal surgery—any antibiotics given by any route. They found a 75% reduction in surgical wound infection and pulled no punches in their conclusions. They wrote that it was now unethical to do colorectal surgery without prophylactic antibiotic cover. I found that very interesting, but, having just begun as an attending surgeon, I went on to other things and forgot it. Its senior author was one of the true fathers of this science [
2]. …