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Archives of Gynecology and Obstetrics
Erschienen in: Archives of Gynecology and Obstetrics 3/2007

01.09.2007 | Case Report

HPV induced ovarian squamous cell carcinoma: case report and review of the literature

verfasst von: J. Verguts, F. Amant, Ph. Moerman, I. Vergote

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2007

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Abstract

Background

Ovarian squamous cell carcinoma is usually derived from a teratoma, a Brenner tumour or endometriosis. Association with an HPV infection is rare.

Case

A fourth case of ovarian squamous cell cancer associated with HR-HPV is presented. Debulking for stage IIIc ovarian squamous cell cancer was performed and she received adjuvant combination chemotherapy. She developed bone metastases and received radiotherapy. The Progression of these metastases and the newly developed metastases did not respond to an oral tyrosine kinase inhibitor (gefitinib).

Conclusion

The development of bone metastases in association with an ovarian squamous cell carcinoma is a rare finding, and it did not respond to treatment with a tyrosine kinase. A review of literature is presented.
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Metadaten
Titel
HPV induced ovarian squamous cell carcinoma: case report and review of the literature
verfasst von
J. Verguts
F. Amant
Ph. Moerman
I. Vergote
Publikationsdatum
01.09.2007
Verlag
Springer-Verlag
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 3/2007
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-007-0333-5

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