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Archives of Orthopaedic and Trauma Surgery

Erschienen in:

01.04.2013 | Trauma Surgery

Hyponatremia at admission is associated with in-hospital death in patients with hip fracture

verfasst von: Tetsuo Hagino, Satoshi Ochiai, Yoshiyuki Watanabe, Shinya Senga, Masanori Saito, Yoshihiro Takayama, Masanori Wako, Takashi Ando, Eiichi Sato, Hirotaka Haro

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 4/2013

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Abstract

Purpose

Hyponatremia in hospitalized patients has been reported to be associated with in-hospital mortality. We studied patients treated at our hospital for hip fracture regarding the factors related to hyponatremia at admission.

Methods

Among 580 patients aged 60 years or above who were admitted to our hospital since January 1997 for treatment of hip fracture, 512 patients (110 males, 402 females) from whom serum sodium level at admission was available were studied. In 512 patients, the age at injury ranged from 60 to 103 (mean 82.6) years. Fracture types were femoral neck fracture in 191 patients, and trochanteric fracture in 321. These patients were divided into two groups by the blood sodium level at admission: a hyponatremia group with sodium levels lower than 135 mEq/L, and a normonatremia group with sodium levels within normal range. The age, gender, fracture type, residence before injury, pre-injury walking capability, anemia at admission, liver function, kidney function, inflammatory status, urinary glucose status, lung disease, ECG abnormality, systemic chronic disease, status of dementia, treatment modality, hospital stay (days), and in-hospital death were investigated. First a univariate study was conducted to identify the factors that differ significantly between the two groups. Then multivariate analysis was conducted using the parameters with significant difference as independent variables

Results

Hyponatremia was found in 49 of 512 (9.6 %) patients. In univariate analyses, six factors (age; residence before injury; anemia; dementia; treatment modality; in-hospital death) were significantly different between the hyponatremia group and normonatremia group. Multivariate analysis identified in-hospital death [odds ratio (OR) = 3.64, p = 0.035] and age (OR = 1.05, p = 0.029) as independently associated with hypernatremia.

Conclusion

Hyponatremia at admission is prevalent in old aged patients with fracture, and is related to in-hospital death.

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Titel: Hyponatremia at admission is associated with in-hospital death in patients with hip fracture
verfasst von: Tetsuo Hagino
Satoshi Ochiai
Yoshiyuki Watanabe
Shinya Senga
Masanori Saito
Yoshihiro Takayama
Masanori Wako
Takashi Ando
Eiichi Sato
Hirotaka Haro
Publikationsdatum: 01.04.2013
Verlag: Springer-Verlag
Erschienen in: Archives of Orthopaedic and Trauma Surgery / Ausgabe 4/2013
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-013-1693-x

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Hyponatremia at admission is associated with in-hospital death in patients with hip fracture