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World Journal of Urology
Erschienen in: World Journal of Urology 1/2016

01.01.2016 | Topic Paper

Immune checkpoint inhibitors: a new frontier in bladder cancer

verfasst von: Max Kates, Nikolai A. Sopko, Hotaka Matsui, Charles G. Drake, Noah M. Hahn, Trinity J. Bivalacqua

Erschienen in: World Journal of Urology | Ausgabe 1/2016

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Abstract

Immunotherapy is rapidly changing the field of urologic oncology. In this review, we discuss the role of the immune system in general and place a particular emphasis on the biology of the immune checkpoint and its role in cancer. Bladder cancer, as one of the most immunogenic neoplasms, is an exciting target for immune checkpoint inhibition. Early preclinical data and human trial experience suggest that this new drug class may shape bladder cancer therapy for years to come.
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Metadaten
Titel
Immune checkpoint inhibitors: a new frontier in bladder cancer
verfasst von
Max Kates
Nikolai A. Sopko
Hotaka Matsui
Charles G. Drake
Noah M. Hahn
Trinity J. Bivalacqua
Publikationsdatum
01.01.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
World Journal of Urology / Ausgabe 1/2016
Print ISSN: 0724-4983
Elektronische ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-015-1709-y

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