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European Journal of Clinical Microbiology & Infectious Diseases

Erschienen in:

15.07.2021 | Brief Report

Impact of a 4-year antimicrobial stewardship program implemented in a Greek tertiary hospital

verfasst von: Konstantina Chrysou, Olympia Zarkotou, Sofia Kalofolia, Panagiota Papagiannakopoulou, Vasiliki Mamali, Georgios Chrysos, Katina Themeli-Digalaki, Nikolaos Sypsas, Athanasios Tsakris, Spyros Pournaras

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 1/2022

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Abstract

This study aimed to investigate the effects of a 4-year antibiotic stewardship program (ASP) in a tertiary hospital. We monitored data for 2015 (pre-intervention) and 2016–2019 (post-intervention) about antibiotic consumption (DDD/100 bed days), Clostridioides difficile infections (CDIs), resistance rates, length of stay (LOS), and annual antibiotic costs. Significant reductions were observed for total antibiotics/colistin/carbapenems/quinolones/tigecycline consumption and resistance rates of Pseudomonas aeruginosa, Klebsiella pneumoniae, and vancomycin-resistant enterococci. Considerable reductions occurred for LOS (4.18 [2015]/3.0 [2019] days), CDIs (1.47 [2015]/0.86 [2019] per 1000 patients), antibiotic cost/patient (39.45€ [2015]/23.69€ [2019]). The ASP was successful in reducing antibiotic consumption, antibiotic costs, length of hospital stay, and CDIs.

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Titel: Impact of a 4-year antimicrobial stewardship program implemented in a Greek tertiary hospital
verfasst von: Konstantina Chrysou
Olympia Zarkotou
Sofia Kalofolia
Panagiota Papagiannakopoulou
Vasiliki Mamali
Georgios Chrysos
Katina Themeli-Digalaki
Nikolaos Sypsas
Athanasios Tsakris
Spyros Pournaras
Publikationsdatum: 15.07.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 1/2022
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-021-04290-7

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