Skip to main content
Erschienen in: European Journal of Trauma and Emergency Surgery 4/2022

14.02.2022 | Original Article

Improvement of mortality in severe liver injury after trauma center implementation: a propensity score matched study

verfasst von: Donghwan Choi, Junsik Kwon, Kyoungwon Jung, Byung Hee Kang

Erschienen in: European Journal of Trauma and Emergency Surgery | Ausgabe 4/2022

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To evaluate changes in the management and outcome of severe liver injury after trauma center implementation.

Methods

Trauma patients with severe liver injury (organ injury scale score ≥ 4) treated between January 2011 and December 2020 were retrospectively reviewed. A trauma center was built in 2016 at our institution, and patients were dichotomized into two groups: before trauma center (BTC) and after trauma center (ATC) group. Treatment methods and outcomes were compared between the groups with 1:1 propensity score matching.

Results

We included 50 patients in the BTC group and 104 patients in the ATC group. Patients in the ATC group had frequent utilization of angiography (16% vs 47.1%, p < 0.001), faster transfusion [84 (37–152) min vs 17 (10–79) min, p < 0.001], and less fluid administration within 24 h [8.3 (5.7–13.7) L vs 5.7 (3.1–10.1) L, p = 0.002]. However, mortality rate was not significantly different between the groups (26.0% vs 20.2%, p = 0.416). 1:1 propensity score matching was performed using the variables of age, injury severity score, systolic blood pressure, Glasgow Coma Scale, and initial base excess level. After matching, the mortality rate (26.0% vs 10.0%, p = 0.037) and ventilator application (74.0% vs 54.0%, p = 0.037) significantly improved.

Conclusion

Severe liver injury management improved after trauma center implementation.
Literatur
1.
Zurück zum Zitat Boese CK, Hackl M, Müller LP, Ruchholtz S, Frink M, Lechler P. Nonoperative management of blunt hepatic trauma: a systematic review. J Trauma Acute Care Surg. 2015;79:654–60.CrossRef Boese CK, Hackl M, Müller LP, Ruchholtz S, Frink M, Lechler P. Nonoperative management of blunt hepatic trauma: a systematic review. J Trauma Acute Care Surg. 2015;79:654–60.CrossRef
2.
Zurück zum Zitat Carrillo EH, Richardson JD. The current management of hepatic trauma. Adv Surg. 2001;35:39–59.PubMed Carrillo EH, Richardson JD. The current management of hepatic trauma. Adv Surg. 2001;35:39–59.PubMed
3.
Zurück zum Zitat Piper GL, Peitzman AB. Current management of hepatic trauma. Surg Clin North Am. 2010;90:775–85.CrossRef Piper GL, Peitzman AB. Current management of hepatic trauma. Surg Clin North Am. 2010;90:775–85.CrossRef
4.
Zurück zum Zitat Ward J, Alarcon L, Peitzman AB. Management of blunt liver injury: what is new? Eur J Trauma Emerg Surg. 2015;41:229–37.CrossRef Ward J, Alarcon L, Peitzman AB. Management of blunt liver injury: what is new? Eur J Trauma Emerg Surg. 2015;41:229–37.CrossRef
5.
Zurück zum Zitat Hollands MJ, Little JM. Perihepatic packing: its role in the management of liver trauma. Aust N Z J Surg. 1989;59:21–4.CrossRef Hollands MJ, Little JM. Perihepatic packing: its role in the management of liver trauma. Aust N Z J Surg. 1989;59:21–4.CrossRef
6.
Zurück zum Zitat Mattox KL. Introduction, background, and future projections of damage control surgery. Surg Clin North Am. 1997;77:753–9.CrossRef Mattox KL. Introduction, background, and future projections of damage control surgery. Surg Clin North Am. 1997;77:753–9.CrossRef
7.
Zurück zum Zitat Rotondo MF, Schwab CW, McGonigal MD, Phillips GR, 3rd, Fruchterman TM, Kauder DR, et al. “Damage control”: an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35:375–82 (discussion 82–3). Rotondo MF, Schwab CW, McGonigal MD, Phillips GR, 3rd, Fruchterman TM, Kauder DR, et al. “Damage control”: an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35:375–82 (discussion 82–3).
8.
Zurück zum Zitat Mohr AM, Lavery RF, Barone A, Bahramipour P, Magnotti LJ, Osband AJ, et al. Angiographic embolization for liver injuries: low mortality, high morbidity. J Trauma. 2003;55:1077–81 (discussion 81–2). Mohr AM, Lavery RF, Barone A, Bahramipour P, Magnotti LJ, Osband AJ, et al. Angiographic embolization for liver injuries: low mortality, high morbidity. J Trauma. 2003;55:1077–81 (discussion 81–2).
9.
Zurück zum Zitat Sivrikoz E, Teixeira PG, Resnick S, Inaba K, Talving P, Demetriades D. Angiointervention: an independent predictor of survival in high-grade blunt liver injuries. Am J Surg. 2015;209:742–6.CrossRef Sivrikoz E, Teixeira PG, Resnick S, Inaba K, Talving P, Demetriades D. Angiointervention: an independent predictor of survival in high-grade blunt liver injuries. Am J Surg. 2015;209:742–6.CrossRef
10.
Zurück zum Zitat Coccolini F, Coimbra R, Ordonez C, Kluger Y, Vega F, Moore EE, et al. Liver trauma: WSES 2020 guidelines. World J Emerg Surg. 2020;15:24.CrossRef Coccolini F, Coimbra R, Ordonez C, Kluger Y, Vega F, Moore EE, et al. Liver trauma: WSES 2020 guidelines. World J Emerg Surg. 2020;15:24.CrossRef
11.
Zurück zum Zitat Jung K, Kim Y, Heo Y, Lee JC, Youn S, Moon J, et al. Management of severe blunt liver injuries by applying the damage control strategies with packing-oriented surgery: experiences at a single institution in Korea. Hepatogastroenterology. 2015;62:410–6.PubMed Jung K, Kim Y, Heo Y, Lee JC, Youn S, Moon J, et al. Management of severe blunt liver injuries by applying the damage control strategies with packing-oriented surgery: experiences at a single institution in Korea. Hepatogastroenterology. 2015;62:410–6.PubMed
12.
Zurück zum Zitat Kang BH, Jung K, Choi D, Kwon J. Early re-laparotomy for patients with high-grade liver injury after damage-control surgery and perihepatic packing. Surg Today. 2021;51:891–6.CrossRef Kang BH, Jung K, Choi D, Kwon J. Early re-laparotomy for patients with high-grade liver injury after damage-control surgery and perihepatic packing. Surg Today. 2021;51:891–6.CrossRef
13.
Zurück zum Zitat Moore EE, Cogbill TH, Jurkovich GJ, Shackford SR, Malangoni MA, Champion HR. Organ injury scaling: spleen and liver (1994 revision). J Trauma. 1994 revision. 1995;38:323–4. Moore EE, Cogbill TH, Jurkovich GJ, Shackford SR, Malangoni MA, Champion HR. Organ injury scaling: spleen and liver (1994 revision). J Trauma. 1994 revision. 1995;38:323–4.
14.
Zurück zum Zitat Huh Y, Kwon J, Moon J, Kang BH, Kim S, Yoo J, et al. An evaluation of the effect of performance improvement and patient safety program implemented in a new regional trauma Center of Korea. J Korean Med Sci. 2021;36:e149.CrossRef Huh Y, Kwon J, Moon J, Kang BH, Kim S, Yoo J, et al. An evaluation of the effect of performance improvement and patient safety program implemented in a new regional trauma Center of Korea. J Korean Med Sci. 2021;36:e149.CrossRef
15.
Zurück zum Zitat Gaski IA, Skattum J, Brooks A, Koyama T, Eken T, Naess PA, et al. Decreased mortality, laparotomy, and embolization rates for liver injuries during a 13-year period in a major Scandinavian trauma center. Trauma Surg Acute Care Open. 2018;3:e000205.CrossRef Gaski IA, Skattum J, Brooks A, Koyama T, Eken T, Naess PA, et al. Decreased mortality, laparotomy, and embolization rates for liver injuries during a 13-year period in a major Scandinavian trauma center. Trauma Surg Acute Care Open. 2018;3:e000205.CrossRef
16.
Zurück zum Zitat Feliciano DV, Mattox KL, Moore EE, Ball CG, Kozar R, Alam HB, et al. Trauma. 9th ed. New York: McGraw-Hill; 2020. Feliciano DV, Mattox KL, Moore EE, Ball CG, Kozar R, Alam HB, et al. Trauma. 9th ed. New York: McGraw-Hill; 2020.
17.
Zurück zum Zitat Polanco P, Leon S, Pineda J, Puyana JC, Ochoa JB, Alarcon L, et al. Hepatic resection in the management of complex injury to the liver. J Trauma. 2008;65:1264–9 (discussion 9–70) Polanco P, Leon S, Pineda J, Puyana JC, Ochoa JB, Alarcon L, et al. Hepatic resection in the management of complex injury to the liver. J Trauma. 2008;65:1264–9 (discussion 9–70)
18.
Zurück zum Zitat Tsugawa K, Koyanagi N, Hashizume M, Ayukawa K, Wada H, Tomikawa M, et al. Anatomic resection for severe blunt liver trauma in 100 patients: significant differences between young and elderly. World J Surg. 2002;26:544–9 (discussion 9). Tsugawa K, Koyanagi N, Hashizume M, Ayukawa K, Wada H, Tomikawa M, et al. Anatomic resection for severe blunt liver trauma in 100 patients: significant differences between young and elderly. World J Surg. 2002;26:544–9 (discussion 9).
19.
Zurück zum Zitat Flint LM, Mays ET, Aaron WS, Fulton RL, Polk HC. Selectivity in the management of hepatic trauma. Ann Surg. 1977;185:613–8.CrossRef Flint LM, Mays ET, Aaron WS, Fulton RL, Polk HC. Selectivity in the management of hepatic trauma. Ann Surg. 1977;185:613–8.CrossRef
20.
Zurück zum Zitat Doklestić K, Stefanović B, Gregorić P, Ivančević N, Lončar Z, Jovanović B, et al. Surgical management of AAST grades III–V hepatic trauma by Damage control surgery with perihepatic packing and Definitive hepatic repair-single centre experience. World J Emerg Surg. 2015;10:34.CrossRef Doklestić K, Stefanović B, Gregorić P, Ivančević N, Lončar Z, Jovanović B, et al. Surgical management of AAST grades III–V hepatic trauma by Damage control surgery with perihepatic packing and Definitive hepatic repair-single centre experience. World J Emerg Surg. 2015;10:34.CrossRef
21.
Zurück zum Zitat Kaptanoglu L, Kurt N, Sikar HE. Current approach to liver traumas. Int J Surg. 2017;39:255–9.CrossRef Kaptanoglu L, Kurt N, Sikar HE. Current approach to liver traumas. Int J Surg. 2017;39:255–9.CrossRef
22.
Zurück zum Zitat Baldoni F, Di Saverio S, Antonacci N, Coniglio C, Giugni A, Montanari N, et al. Refinement in the technique of perihepatic packing: a safe and effective surgical hemostasis and multidisciplinary approach can improve the outcome in severe liver trauma. Am J Surg. 2011;201:e5–14.CrossRef Baldoni F, Di Saverio S, Antonacci N, Coniglio C, Giugni A, Montanari N, et al. Refinement in the technique of perihepatic packing: a safe and effective surgical hemostasis and multidisciplinary approach can improve the outcome in severe liver trauma. Am J Surg. 2011;201:e5–14.CrossRef
23.
Zurück zum Zitat MacKenzie S, Kortbeek JB, Mulloy R, Hameed SM. Recent experiences with a multidisciplinary approach to complex hepatic trauma. Injury. 2004;35:869–77.CrossRef MacKenzie S, Kortbeek JB, Mulloy R, Hameed SM. Recent experiences with a multidisciplinary approach to complex hepatic trauma. Injury. 2004;35:869–77.CrossRef
24.
Zurück zum Zitat Suen K, Skandarajah AR, Knowles B, Judson R, Thomson BN. Changes in the management of liver trauma leading to reduced mortality: 15-year experience in a major trauma centre. ANZ J Surg. 2016;86:894–9.CrossRef Suen K, Skandarajah AR, Knowles B, Judson R, Thomson BN. Changes in the management of liver trauma leading to reduced mortality: 15-year experience in a major trauma centre. ANZ J Surg. 2016;86:894–9.CrossRef
25.
Zurück zum Zitat Wise R, Faurie M, Malbrain MLNG, Hodgson E. Strategies for intravenous fluid resuscitation in trauma patients. World J Surg. 2017;41:1170–83.CrossRef Wise R, Faurie M, Malbrain MLNG, Hodgson E. Strategies for intravenous fluid resuscitation in trauma patients. World J Surg. 2017;41:1170–83.CrossRef
Metadaten
Titel
Improvement of mortality in severe liver injury after trauma center implementation: a propensity score matched study
verfasst von
Donghwan Choi
Junsik Kwon
Kyoungwon Jung
Byung Hee Kang
Publikationsdatum
14.02.2022
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Trauma and Emergency Surgery / Ausgabe 4/2022
Print ISSN: 1863-9933
Elektronische ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-022-01909-y

Weitere Artikel der Ausgabe 4/2022

European Journal of Trauma and Emergency Surgery 4/2022 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.