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Graefe's Archive for Clinical and Experimental Ophthalmology

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14.11.2019 | Retinal Disorders

Increased choroidal blood flow and choroidal thickness in patients with hypertensive chorioretinopathy

verfasst von: Michiyuki Saito, Kousuke Noda, Wataru Saito, Kiriko Hirooka, Yuki Hashimoto, Susumu Ishida

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 2/2020

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Abstract

Purpose

To investigate the alterations of central choroidal thickness (CCT) and macular choroidal blood flow in patients with hypertensive chorioretinopathy treated with antihypertensive agents.

Methods

In retrospective observational case series, ten eyes of 9 patients with hypertensive chorioretinopathy were enrolled (5 men and 4 women; 43.1 ± 19.6 years of age). CCT and mean blur rate (MBR) had been observed during follow-up using enhanced depth imaging optical coherence tomography and laser speckle flowgraphy, respectively.

Results

With the medication for hypertension, serous retinal detachment (SRD) disappeared in all the eyes (mean period, 57.8 ± 50.4 days), and the mean blood pressure decreased (122.7 ± 13.0 mmHg and 93.4 ± 13.2 mmHg at the initial visit and at the day of subretinal fluid absorption, respectively; P < 0.01). The mean logMAR value of best corrected visual acuity showed a tendency toward improvement with the resolution of SRD (0.15 ± 0.30 and 0.08 ± 0.28, P = 0.15). The average MBR significantly decreased when SRD was absorbed (11.4 ± 4.5 and 7.7 ± 2.2, P < 0.01). Similarly, the mean values of CCT decreased (473.2 ± 218.0 μm and 325.7 ± 112.0 μm, P < 0.01). The changing rates of CCT and MBR showed a significant positive correlation (P < 0.01, R = 0.88).

Conclusion

The current study demonstrated a novel finding that choroidal blood flow velocity and thickness concurrently increased in the acute phase of hypertensive chorioretinopathy, suggesting the role of choroidal hyperperfusion in the pathogenesis of hypertensive chorioretinopathy.

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Titel: Increased choroidal blood flow and choroidal thickness in patients with hypertensive chorioretinopathy
verfasst von: Michiyuki Saito
Kousuke Noda
Wataru Saito
Kiriko Hirooka
Yuki Hashimoto
Susumu Ishida
Publikationsdatum: 14.11.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 2/2020
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-019-04511-y

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Increased choroidal blood flow and choroidal thickness in patients with hypertensive chorioretinopathy

Abstract

Purpose

Methods

Results

Conclusion

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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