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17.02.2018 | Review

Intradural spinal tumors in adults—update on management and outcome

verfasst von: Malte Ottenhausen, Georgios Ntoulias, Imithri Bodhinayake, Finn-Hannes Ruppert, Stefan Schreiber, Annette Förschler, John A. Boockvar, Andreas Jödicke

Erschienen in: Neurosurgical Review | Ausgabe 2/2019

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Abstract

Among spinal tumors that occur intradurally, meningiomas, nerve sheath tumors, ependymomas, and astrocytomas are the most common. While a spinal MRI is the state of the art to diagnose intradural spinal tumors, in some cases CT scans, angiography, CSF analyses, and neurophysiological examination can be valuable. The management of these lesions depends not only on the histopathological diagnosis but also on the clinical presentation and the anatomical location, allowing either radical resection as with most extramedullary lesions or less invasive strategies as with intramedullary lesions. Although intramedullary lesions are rare and sometimes difficult to manage, well-planned treatment can achieve excellent outcome without treatment-related deficits. Technical advances in imaging, neuromonitoring, minimally invasive approaches, and radiotherapy have improved the outcome of intradural spinal tumors. However, the outcome in malignant intramedullary tumors remains poor. While surgery is the mainstay treatment for many of these lesions, radiation and chemotherapy are of growing importance in recurrent and multilocular disease. We reviewed the literature on this topic to provide an overview of spinal cord tumors, treatment strategies, and outcomes. Typical cases of extra- and intramedullary tumors are presented to illustrate management options and outcomes.

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Titel: Intradural spinal tumors in adults—update on management and outcome
verfasst von: Malte Ottenhausen
Georgios Ntoulias
Imithri Bodhinayake
Finn-Hannes Ruppert
Stefan Schreiber
Annette Förschler
John A. Boockvar
Andreas Jödicke
Publikationsdatum: 17.02.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Neurosurgical Review / Ausgabe 2/2019
Print ISSN: 0344-5607
Elektronische ISSN: 1437-2320
DOI: https://doi.org/10.1007/s10143-018-0957-x

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