Erschienen in:
14.03.2019 | Letter to the Editor
Intravascular Occlusion by Leukemic Blast Cells Causing Multiplex Hand Necrosis in a Patient with Acute Myeloid Leukemia
verfasst von:
László Pinczés, Ferenc Magyari, Gyula Reményi, György Pfliegler, Sándor Barna, Judit Bedekovics, Árpád Illés
Erschienen in:
Pathology & Oncology Research
|
Ausgabe 2/2020
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Excerpt
In April 2017, a 76 years old female patient with a history of hypertension, hypothyreosis and left renal artery stenosis was diagnosed with acute myeloid leukemia (AML; FAB M4). She presented with poor prognostic markers including complex karyotype with wild-type FLT-3 and NPM-1 mutations. After induction chemotherapy (3 + 7 regimen, consisting 60 mg/m2 of daunorubicin and 100 mg/m2 of cytosine arabinoside) she experienced treatment failure with progressive disease and newly detected peripheral blast cells. After receiving dismal results she withdrew consent for further treatment. …