Skip to main content
Erschienen in: The Journal of Obstetrics and Gynecology of India 1/2017

30.01.2017 | EDITORIAL

Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?

verfasst von: Gautam N. Allahbadia

Erschienen in: The Journal of Obstetrics and Gynecology of India | Ausgabe 1/2017

Einloggen, um Zugang zu erhalten

Abstract

The diagnosis of an unsuspected leiomyosarcoma after hysterectomy for the treatment of a presumed benign leiomyoma is a rare but highly clinically significant event. In order to facilitate removal of large uterine specimens using a minimally invasive surgical approach, morcellation with extraction in pieces is often performed. In the event of unsuspected malignancy, this may result in abdominal dispersion of the tumor and contribute to poorer survival. Modern surgical innovations always work toward improving minimally invasive strategies. Laparoscopy, rooted in practices for years, supplanted laparotomy for many indications. For extraction of large uteri, morcellation is currently the only way to externalize surgical specimens (myomas, uteri), without increasing the skin opening while allowing to reduce postoperative complications when compared to laparotomy. However, in 2014, the Food and Drug Administration warned against the use of uterine morcellation because of an oncological risk. Some practicing academicians have challenged this recommendation. The incidence of uterine sarcomas is still poorly identified and preoperative diagnostic facilities remain inadequate. The small number of retrospective studies currently available do not reinforce any recommendation. The evaluation of morcellation devices and the improvement of preoperative diagnostic modalities (Imaging, preoperative Biopsy) are being improvised continually so as to minimize the oncological risks. Even during conventional myomectomy, tissue spillage occurs during resection of leiomyoma(s). Adverse oncologic outcomes of tissue morcellation should be mitigated through improved patient selection, preoperative investigations, and novel techniques that minimize tissue dispersion. Preoperative endometrial biopsy and cervical assessment to avoid morcellation of potentially detectable malignant and premalignant conditions is recommended.
Literatur
1.
Zurück zum Zitat Parker W, Pritts E, Olive D. Risk of morcellation of uterine leiomyosarcomas in laparoscopic supracervical hysterectomy and laparoscopic myomectomy, a retrospective trial including 4791 women. J Minim Invasive Gynecol. 2015;22(4):696–7. doi:10.1016/j.jmig.2015.01.015.CrossRefPubMed Parker W, Pritts E, Olive D. Risk of morcellation of uterine leiomyosarcomas in laparoscopic supracervical hysterectomy and laparoscopic myomectomy, a retrospective trial including 4791 women. J Minim Invasive Gynecol. 2015;22(4):696–7. doi:10.​1016/​j.​jmig.​2015.​01.​015.CrossRefPubMed
4.
Zurück zum Zitat Singh SS, Scott S, Bougie O et al. Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy. J Obstet Gynaecol Can. 2015;37(1):68–81.CrossRefPubMed Singh SS, Scott S, Bougie O et al. Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy. J Obstet Gynaecol Can. 2015;37(1):68–81.CrossRefPubMed
5.
Zurück zum Zitat Nugent W, Engelke G, Reicke S et al. Laparoscopic supracervical hysterectomy or myomectomy with power morcellation: risk of uterine leiomyosarcomas: a retrospective trial including 35.161 women in Germany. J Minim Invasive Gynecol. 2015;22(6S):S2–3. doi:10.1016/j.jmig.2015.08.013.CrossRefPubMed Nugent W, Engelke G, Reicke S et al. Laparoscopic supracervical hysterectomy or myomectomy with power morcellation: risk of uterine leiomyosarcomas: a retrospective trial including 35.161 women in Germany. J Minim Invasive Gynecol. 2015;22(6S):S2–3. doi:10.​1016/​j.​jmig.​2015.​08.​013.CrossRefPubMed
7.
Zurück zum Zitat Zhang J, Li T, Zhang J et al. Clinical characteristics and prognosis of unexpected uterine sarcoma after hysterectomy for presumed myoma with and without transvaginal scalpel morcellation. Int J Gynecol Cancer. 2016;26(3):456–63. doi:10.1097/IGC.0000000000000638.CrossRefPubMed Zhang J, Li T, Zhang J et al. Clinical characteristics and prognosis of unexpected uterine sarcoma after hysterectomy for presumed myoma with and without transvaginal scalpel morcellation. Int J Gynecol Cancer. 2016;26(3):456–63. doi:10.​1097/​IGC.​0000000000000638​.CrossRefPubMed
8.
Zurück zum Zitat Parker WH, Kaunitz AM, Pritts EA et al. Leiomyoma Morcellation Review Group US Food and Drug Administration’s Guidance Regarding Morcellation of Leiomyomas: Well-Intentioned, But Is It Harmful for Women? Obstet Gynecol. 2016;127(1):18–22. doi:10.1097/AOG.0000000000001157.CrossRefPubMed Parker WH, Kaunitz AM, Pritts EA et al. Leiomyoma Morcellation Review Group US Food and Drug Administration’s Guidance Regarding Morcellation of Leiomyomas: Well-Intentioned, But Is It Harmful for Women? Obstet Gynecol. 2016;127(1):18–22. doi:10.​1097/​AOG.​0000000000001157​.CrossRefPubMed
10.
Zurück zum Zitat Park BY, Leslie KO, Chen L et al. A case of simultaneous benign metastasizing leiomyomas and disseminated peritoneal leiomyomatosis following endoscopic power morcellation for uterine disease. Female Pelvic Med Reconstr Surg. 2017;23(1):e1–3.CrossRefPubMed Park BY, Leslie KO, Chen L et al. A case of simultaneous benign metastasizing leiomyomas and disseminated peritoneal leiomyomatosis following endoscopic power morcellation for uterine disease. Female Pelvic Med Reconstr Surg. 2017;23(1):e1–3.CrossRefPubMed
12.
Zurück zum Zitat Perkins RB, Handal-Orefice R, Hanchate AD et al. Risk of undetected cancer at the time of laparoscopic supracervical hysterectomy and laparoscopic myomectomy: implications for the use of power morcellation. Womens Health Issues. 2016;26(1):21–6. doi:10.1016/j.whi.2015.09.008.CrossRefPubMed Perkins RB, Handal-Orefice R, Hanchate AD et al. Risk of undetected cancer at the time of laparoscopic supracervical hysterectomy and laparoscopic myomectomy: implications for the use of power morcellation. Womens Health Issues. 2016;26(1):21–6. doi:10.​1016/​j.​whi.​2015.​09.​008.CrossRefPubMed
14.
Zurück zum Zitat Rechberger T, Miotła P, Futyma K et al. Power morcellation for women undergoing laparoscopic supracervical hysterectomy—safety of procedure and clinical experience from 426 cases. Ginekol Pol. 2016;87(8):546–51. doi:10.5603/GP.2016.0042.CrossRefPubMed Rechberger T, Miotła P, Futyma K et al. Power morcellation for women undergoing laparoscopic supracervical hysterectomy—safety of procedure and clinical experience from 426 cases. Ginekol Pol. 2016;87(8):546–51. doi:10.​5603/​GP.​2016.​0042.CrossRefPubMed
16.
Zurück zum Zitat Huang BS, Yang MH, Wang PH et al. Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation. Reprod Biol Endocrinol. 2016;14(1):64.CrossRefPubMedPubMedCentral Huang BS, Yang MH, Wang PH et al. Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation. Reprod Biol Endocrinol. 2016;14(1):64.CrossRefPubMedPubMedCentral
17.
19.
Zurück zum Zitat Anapolski M, Panayotopoulos D, Alkatout I et al. Preclinical safety testing for morcellation and extraction for an endobag with sealable ports: in vitro pilot study. Surg Endosc. 2017;31(1):494–500. doi:10.1007/s00464-016-4969-8.CrossRefPubMed Anapolski M, Panayotopoulos D, Alkatout I et al. Preclinical safety testing for morcellation and extraction for an endobag with sealable ports: in vitro pilot study. Surg Endosc. 2017;31(1):494–500. doi:10.​1007/​s00464-016-4969-8.CrossRefPubMed
21.
Zurück zum Zitat Skorstad M, Kent A, Lieng M. Uterine leiomyosarcoma—incidence, treatment, and the impact of morcellation: a nationwide cohort study. Acta Obstet Gynecol Scand. 2016;95(9):984–90. doi:10.1111/aogs.12930.CrossRefPubMed Skorstad M, Kent A, Lieng M. Uterine leiomyosarcoma—incidence, treatment, and the impact of morcellation: a nationwide cohort study. Acta Obstet Gynecol Scand. 2016;95(9):984–90. doi:10.​1111/​aogs.​12930.CrossRefPubMed
23.
Zurück zum Zitat Siedhoff MT, Doll KM, Clarke-Pearson DL et al. Laparoscopic hysterectomy with morcellation vs abdominal hysterectomy for presumed fibroids: an updated decision analysis following the 2014 Food and Drug Administration safety communications. Am J Obstet Gynecol. 2016;. doi:10.1016/j.ajog.2016.11.1039.PubMed Siedhoff MT, Doll KM, Clarke-Pearson DL et al. Laparoscopic hysterectomy with morcellation vs abdominal hysterectomy for presumed fibroids: an updated decision analysis following the 2014 Food and Drug Administration safety communications. Am J Obstet Gynecol. 2016;. doi:10.​1016/​j.​ajog.​2016.​11.​1039.PubMed
24.
Zurück zum Zitat Harris JA, Swenson CW, Uppal S et al. Practice patterns and postoperative complications before and after Food and Drug Administration safety communication on power morcellation. Am J Obstet Gynecol. 2015;. doi:10.1016/j.ajog.2015.08.047.PubMed Harris JA, Swenson CW, Uppal S et al. Practice patterns and postoperative complications before and after Food and Drug Administration safety communication on power morcellation. Am J Obstet Gynecol. 2015;. doi:10.​1016/​j.​ajog.​2015.​08.​047.PubMed
Metadaten
Titel
Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?
verfasst von
Gautam N. Allahbadia
Publikationsdatum
30.01.2017
Verlag
Springer India
Erschienen in
The Journal of Obstetrics and Gynecology of India / Ausgabe 1/2017
Print ISSN: 0971-9202
Elektronische ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-017-0970-y

Weitere Artikel der Ausgabe 1/2017

The Journal of Obstetrics and Gynecology of India 1/2017 Zur Ausgabe

Alter verschlechtert Prognose bei Endometriumkarzinom

11.05.2024 Endometriumkarzinom Nachrichten

Ein höheres Alter bei der Diagnose eines Endometriumkarzinoms ist mit aggressiveren Tumorcharakteristika assoziiert, scheint aber auch unabhängig von bekannten Risikofaktoren die Prognose der Erkrankung zu verschlimmern.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Erhöhte Mortalität bei postpartalem Brustkrebs

07.05.2024 Mammakarzinom Nachrichten

Auch für Trägerinnen von BRCA-Varianten gilt: Erkranken sie fünf bis zehn Jahre nach der letzten Schwangerschaft an Brustkrebs, ist das Sterberisiko besonders hoch.

Menopausale Hormontherapie für Frauen über 65?

07.05.2024 Klimakterium und Menopause Nachrichten

In den USA erhalten nicht wenige Frauen auch noch im Alter über 65 eine menopausale Hormontherapie. Welche positiven und negativen gesundheitlichen Konsequenzen daraus möglicherweise resultieren, wurde anhand von Versicherungsdaten analysiert.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.