Erschienen in:
22.10.2020 | Thoracic Oncology
Is Newer Actually Better? Where Does the 8th Edition Outperform the 7th Edition of the Esophageal TNM Staging System?
verfasst von:
Siva Raja, MD, PhD, Usman Ahmad, MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 2/2021
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Excerpt
Prognostication is one of the fundamental purposes of stage classification. With additional information, each new iteration allows us to refine the stage groupings such that survival within the stage groupings is more similar and survival among stage groupings is more disparate. The 7th edition of the American Joint Committee on Cancer (AJCC) staging manual for esophageal cancer was in and of itself a monumental endeavor that was powered by the World Esophageal Cancer Collaborative (WECC)
1. WECC-7 was a multi-institutional, multinational collaborative (from 13 institutions from five countries and three continents) that was created for the sole purpose of acquiring data for the creation of the 7th edition staging system. This database accumulated 4627 patients who had undergone an esophagectomy alone for cancer. Several key elements were introduced during this staging system that included (but were not limited to) differentiation by histology, grade of cancer, location, subclassification by number of involved nodes, and further subclassifying T4 into T4a and T4b. Perhaps the most significant contribution was to bring cancers involving the gastroesophageal junction (GEJ) and down to 5 cm of the stomach into the esophageal staging system, where previously they could have been staged between two different staging systems. …
