Skip to main content
Erschienen in: Monatsschrift Kinderheilkunde 4/2008

01.04.2008 | Konsensuspapiere

Konsensuspapier zur Prophylaxe der RSV-Infektion mit Palivizumab und Post-RSV-Atemwegserkrankung

verfasst von: Österreichische Gesellschaft für Kinder- und Jugendheilkunde (ÖGKJ)

Erschienen in: Monatsschrift Kinderheilkunde | Ausgabe 4/2008

Einloggen, um Zugang zu erhalten

Auszug

B. Resch, A. Berger2, G. Bernert3, E. Eber4, T. Frischer5, B. Simma6, A. Zacharasiewicz7, M. Zach4
Literatur
1.
Zurück zum Zitat Abman SH, Ogle JW, Butler-Simon N et al. (1988) Role of respiratory syncytial virus in early hospitalizations for respiratory distress of young infants with cystic fibrosis. J Pediatr 113: 826–830PubMedCrossRef Abman SH, Ogle JW, Butler-Simon N et al. (1988) Role of respiratory syncytial virus in early hospitalizations for respiratory distress of young infants with cystic fibrosis. J Pediatr 113: 826–830PubMedCrossRef
2.
Zurück zum Zitat Arnold SR, Wang EE, Law BJ et al. (1999) Variable morbidity of respiratory syncytial virus infection in patients with underlying lung disease: a review of the PICNIC RSV database. Pediatric Investigators Collaborative Network on Infections in Canada. Pediatr Infect Dis J 18: 866–869PubMedCrossRef Arnold SR, Wang EE, Law BJ et al. (1999) Variable morbidity of respiratory syncytial virus infection in patients with underlying lung disease: a review of the PICNIC RSV database. Pediatric Investigators Collaborative Network on Infections in Canada. Pediatr Infect Dis J 18: 866–869PubMedCrossRef
3.
Zurück zum Zitat Boeckh M, Berrey MM, Bowden RA et al. (2001) Phase 1 evaluation of the respiratory syncytial virus-specific monoclonal antibody palivizumab in recipients of hematopoietic stem cell transplants. J Infect Dis 184: 350–354PubMedCrossRef Boeckh M, Berrey MM, Bowden RA et al. (2001) Phase 1 evaluation of the respiratory syncytial virus-specific monoclonal antibody palivizumab in recipients of hematopoietic stem cell transplants. J Infect Dis 184: 350–354PubMedCrossRef
4.
Zurück zum Zitat Bont L, Steijn M, Van Aalderen WMC et al. (2004) Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection. Thorax 59: 512–516PubMedCrossRef Bont L, Steijn M, Van Aalderen WMC et al. (2004) Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection. Thorax 59: 512–516PubMedCrossRef
5.
Zurück zum Zitat Bramley AM, Vitalis TZ, Wiggs BR et al. (1999) Effects of respiratory syncytial virus persistence on airway responsiveness and inflammation in guinea-pigs. Eur Respir J 14: 1061–1067PubMedCrossRef Bramley AM, Vitalis TZ, Wiggs BR et al. (1999) Effects of respiratory syncytial virus persistence on airway responsiveness and inflammation in guinea-pigs. Eur Respir J 14: 1061–1067PubMedCrossRef
6.
Zurück zum Zitat Buckingham SC, Jafri HS, Bush AJ et al. (2002) A randomized, double-blind, placebo-controlled trial of dexamethasone in severe respiratory syncytial virus (RSV) infection: effects on RSV quantity and clinical outcome. J Infect Dis 2002; 185: 1222–1228 Buckingham SC, Jafri HS, Bush AJ et al. (2002) A randomized, double-blind, placebo-controlled trial of dexamethasone in severe respiratory syncytial virus (RSV) infection: effects on RSV quantity and clinical outcome. J Infect Dis 2002; 185: 1222–1228
7.
Zurück zum Zitat Cole PD, Suh JS, Stiles J et al. (2001) Benign outcome of RSV infection in children with cancer. Med Pediatr Oncol 37: 24–29PubMedCrossRef Cole PD, Suh JS, Stiles J et al. (2001) Benign outcome of RSV infection in children with cancer. Med Pediatr Oncol 37: 24–29PubMedCrossRef
8.
Zurück zum Zitat Döring G, Gusenleitner W, Belohradsky BH et al. (2006) The risk of respiratory syncytial virus-related hospitalizations in preterm infants of 29 to 35 weeks gestational age. Pediatr Infect Dis J 25: 1188–1190CrossRef Döring G, Gusenleitner W, Belohradsky BH et al. (2006) The risk of respiratory syncytial virus-related hospitalizations in preterm infants of 29 to 35 weeks gestational age. Pediatr Infect Dis J 25: 1188–1190CrossRef
9.
Zurück zum Zitat Ermers MJJ, Hoebee B, Hodemaekers HM et al. (2007) IL-13 genetic polymorphism identifies children with late wheezing after respiratory syncytial virus infection. J Allergy Clin Immunol 119: 1086–1091PubMedCrossRef Ermers MJJ, Hoebee B, Hodemaekers HM et al. (2007) IL-13 genetic polymorphism identifies children with late wheezing after respiratory syncytial virus infection. J Allergy Clin Immunol 119: 1086–1091PubMedCrossRef
10.
Zurück zum Zitat Garcia DF, Hiatt PW, Jewell A et al. (2007) Human metapneumovirus and respiratory syncytial virus infections in older children with cystic fibrosis. Pediatr Pulmonol 42: 66–74PubMedCrossRef Garcia DF, Hiatt PW, Jewell A et al. (2007) Human metapneumovirus and respiratory syncytial virus infections in older children with cystic fibrosis. Pediatr Pulmonol 42: 66–74PubMedCrossRef
11.
Zurück zum Zitat Greenough A, Broughton S (2005) Chronic manifestations of respiratory syncytial virus infection in premature infants. Pediatr Infect Dis J 24: S184–188PubMedCrossRef Greenough A, Broughton S (2005) Chronic manifestations of respiratory syncytial virus infection in premature infants. Pediatr Infect Dis J 24: S184–188PubMedCrossRef
12.
Zurück zum Zitat Henderson J, Hilliard TN, Sherriff A et al. and the ALSPAC Study Team (2005) Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: a longitudinal birth cohort study. Pediatr Allergy Immunol 16: 386–392PubMedCrossRef Henderson J, Hilliard TN, Sherriff A et al. and the ALSPAC Study Team (2005) Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: a longitudinal birth cohort study. Pediatr Allergy Immunol 16: 386–392PubMedCrossRef
13.
Zurück zum Zitat Hiatt PW, Grace SC, Kozinetz CA et al. (1999) Effects of viral lower respiratory tract infection on lung function in infants with cystic fibrosis. Pediatrics 103: 619–626PubMedCrossRef Hiatt PW, Grace SC, Kozinetz CA et al. (1999) Effects of viral lower respiratory tract infection on lung function in infants with cystic fibrosis. Pediatrics 103: 619–626PubMedCrossRef
14.
Zurück zum Zitat Horn SD, Smout RJ (2003) Effect of prematurity on respiratory syncytial virus hospital resource use and outcomes. J Pediatr 143: S133–141PubMed Horn SD, Smout RJ (2003) Effect of prematurity on respiratory syncytial virus hospital resource use and outcomes. J Pediatr 143: S133–141PubMed
15.
Zurück zum Zitat Hu C, Wedde-Beer K, Auais A et al. (2002) Nerve growth factor and nerve growth factor receptors in respiratory syncytial virus-infected lungs. Am J Physiol Lung Cell Mol Physiol 283: 494–502 Hu C, Wedde-Beer K, Auais A et al. (2002) Nerve growth factor and nerve growth factor receptors in respiratory syncytial virus-infected lungs. Am J Physiol Lung Cell Mol Physiol 283: 494–502
16.
Zurück zum Zitat Kim CK, Chung CY, Choi SJ et al. (2000) Bronchoalveolar lavage cellular composition in acute asthma and acute bronchiolitis. J Pediatr 137: 517–522PubMedCrossRef Kim CK, Chung CY, Choi SJ et al. (2000) Bronchoalveolar lavage cellular composition in acute asthma and acute bronchiolitis. J Pediatr 137: 517–522PubMedCrossRef
17.
Zurück zum Zitat Kim CK, Kim SW, Park CS et al. (2003) Bronchoalveolar lavage cytokine profiles in acute asthma and acute bronchiolitis. J Allergy Clin Immunol 112: 64–71PubMedCrossRef Kim CK, Kim SW, Park CS et al. (2003) Bronchoalveolar lavage cytokine profiles in acute asthma and acute bronchiolitis. J Allergy Clin Immunol 112: 64–71PubMedCrossRef
18.
Zurück zum Zitat King KA, Hu C, Rodriguez MM et al. (2001) Exaggerated neurogenic inflammation and substance P receptor upregulation in RSV-infected weanling rats. Am J Respir Cell Mol Biol 24: 101–107PubMed King KA, Hu C, Rodriguez MM et al. (2001) Exaggerated neurogenic inflammation and substance P receptor upregulation in RSV-infected weanling rats. Am J Respir Cell Mol Biol 24: 101–107PubMed
19.
Zurück zum Zitat Kneyber MCJ, Steyerberg EW, de Groot R et al. (2000) Long-term effects of respiratory syncytial virus (RSV) bronchiolitis in infants and young children: a quantitative review. Acta Paediatr 89: 654–660PubMedCrossRef Kneyber MCJ, Steyerberg EW, de Groot R et al. (2000) Long-term effects of respiratory syncytial virus (RSV) bronchiolitis in infants and young children: a quantitative review. Acta Paediatr 89: 654–660PubMedCrossRef
20.
Zurück zum Zitat Law BJ, Langley JM, Allen U et al. (2004) The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation. Pediatr Infect Dis J 23: 806–814PubMedCrossRef Law BJ, Langley JM, Allen U et al. (2004) The Pediatric Investigators Collaborative Network on Infections in Canada study of predictors of hospitalization for respiratory syncytial virus infection for infants born at 33 through 35 completed weeks of gestation. Pediatr Infect Dis J 23: 806–814PubMedCrossRef
21.
Zurück zum Zitat Lee KK, Hegele RG, Manfreda J et al. (2007) Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: the Canadian Asthma Primary Prevention Study. Pediatr Pulmonol 42: 290–297PubMedCrossRef Lee KK, Hegele RG, Manfreda J et al. (2007) Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: the Canadian Asthma Primary Prevention Study. Pediatr Pulmonol 42: 290–297PubMedCrossRef
22.
Zurück zum Zitat Madhi SA, Schoub B, Simmank K et al. (2000) Increased burden of respiratory viral associated severe lower respiratory tract infections in children infected with human immunodeficiency virus type-1. J Pediatr 137: 78–84PubMedCrossRef Madhi SA, Schoub B, Simmank K et al. (2000) Increased burden of respiratory viral associated severe lower respiratory tract infections in children infected with human immunodeficiency virus type-1. J Pediatr 137: 78–84PubMedCrossRef
23.
Zurück zum Zitat Malfroot A, Adam G, Ciofu O et al. for the ECFS Vaccination group (2005) Immunisation in the current management of cystic fibrosis patients. J Cyst Fibros 4: 77–87PubMedCrossRef Malfroot A, Adam G, Ciofu O et al. for the ECFS Vaccination group (2005) Immunisation in the current management of cystic fibrosis patients. J Cyst Fibros 4: 77–87PubMedCrossRef
24.
Zurück zum Zitat McCormick J, Southern KW (2007) A survey of palivizumab for infants with cystic fibrosis in the UK. Arch Dis Child 92: 87–88PubMedCrossRef McCormick J, Southern KW (2007) A survey of palivizumab for infants with cystic fibrosis in the UK. Arch Dis Child 92: 87–88PubMedCrossRef
25.
Zurück zum Zitat MedImmune Inc. (2007) Synagis® (palivizumab) for intramuscular administration [online]. Available from URL: http://www.synagis.com/content/sitetools/synagis_pi.pdf [accessed 2007 Jul 8] MedImmune Inc. (2007) Synagis® (palivizumab) for intramuscular administration [online]. Available from URL: http://​www.​synagis.​com/​content/​sitetools/​synagis_​pi.​pdf [accessed 2007 Jul 8]
26.
Zurück zum Zitat Meert K, Heidemann S, Abella B et al. (1990) Does prematurity alter the course of respiratory syncytial virus infection? Crit Care Med 18: 1357–1359PubMedCrossRef Meert K, Heidemann S, Abella B et al. (1990) Does prematurity alter the course of respiratory syncytial virus infection? Crit Care Med 18: 1357–1359PubMedCrossRef
27.
Zurück zum Zitat Noble V, Murray M, Webb MS et al. (1997) Respiratory status and allergy nine to 10 years after acute bronchiolitis. Arch Dis Child 76: 315–319PubMedCrossRef Noble V, Murray M, Webb MS et al. (1997) Respiratory status and allergy nine to 10 years after acute bronchiolitis. Arch Dis Child 76: 315–319PubMedCrossRef
28.
Zurück zum Zitat Nuijten MJ, Wittenberg W, Lebmeier M (2007) Cost effectiveness of palivizumab for respiratory syncytial virus prophylaxis in high-risk children: a UK analysis. Pharmacoeconomics 25: 55–71PubMedCrossRef Nuijten MJ, Wittenberg W, Lebmeier M (2007) Cost effectiveness of palivizumab for respiratory syncytial virus prophylaxis in high-risk children: a UK analysis. Pharmacoeconomics 25: 55–71PubMedCrossRef
29.
Zurück zum Zitat Piedimonte G (2003) Contribution of neuroimmune mechanisms to airway inflammation and remodeling during and after respiratory syncytial virus infection. Pediatr Infect Dis J 22: S66–75PubMedCrossRef Piedimonte G (2003) Contribution of neuroimmune mechanisms to airway inflammation and remodeling during and after respiratory syncytial virus infection. Pediatr Infect Dis J 22: S66–75PubMedCrossRef
30.
Zurück zum Zitat Piedimonte G, Renzetti G, Auais A et al. (2005) Leukotriene synthesis during respiratory syncytial virus bronchiolitis: influence of age and atopy. Pediatr Pulmonol 40: 285–291PubMedCrossRef Piedimonte G, Renzetti G, Auais A et al. (2005) Leukotriene synthesis during respiratory syncytial virus bronchiolitis: influence of age and atopy. Pediatr Pulmonol 40: 285–291PubMedCrossRef
31.
Zurück zum Zitat Red Book® (2006) Report of the Committee on Infectious Diseases, 27th edn. Red Book; American Academy of Pediatrics, Elk Grove Village Red Book® (2006) Report of the Committee on Infectious Diseases, 27th edn. Red Book; American Academy of Pediatrics, Elk Grove Village
32.
Zurück zum Zitat Resch B, Gusenleitner W, Müller W (2002) The impact of respiratory syncytial virus infection: a prospective study in hospitalized infants younger than 2 years. Infection 30: 193–197PubMedCrossRef Resch B, Gusenleitner W, Müller W (2002) The impact of respiratory syncytial virus infection: a prospective study in hospitalized infants younger than 2 years. Infection 30: 193–197PubMedCrossRef
33.
Zurück zum Zitat Resch B, Berger A, Urlesberger B et al. (2004) Österreichische Empfehlungen zur RSV Prophylaxe bei Frühgeborenen mit Palivizumab – Update 2003. Monatschr Kinderheilkd 152: 223–224 Resch B, Berger A, Urlesberger B et al. (2004) Österreichische Empfehlungen zur RSV Prophylaxe bei Frühgeborenen mit Palivizumab – Update 2003. Monatschr Kinderheilkd 152: 223–224
34.
Zurück zum Zitat Resch B, Pasnocht A, Gusenleitner W et al. (2005) Rehospitalisations for respiratory disease and respiratory syncytial virus infection in preterm infants of 29–36 weeks gestational age. J Infect 50: 397–403PubMedCrossRef Resch B, Pasnocht A, Gusenleitner W et al. (2005) Rehospitalisations for respiratory disease and respiratory syncytial virus infection in preterm infants of 29–36 weeks gestational age. J Infect 50: 397–403PubMedCrossRef
35.
Zurück zum Zitat Resch B, Gusenleitner W, Müller W et al. (2006) Observational study of respiratory syncytial virus-associated hospitalizations and use of palivizumab in premature infants aged 29–32 weeks. Eur J Clin Microbiol Infect Dis 25: 120–122PubMedCrossRef Resch B, Gusenleitner W, Müller W et al. (2006) Observational study of respiratory syncytial virus-associated hospitalizations and use of palivizumab in premature infants aged 29–32 weeks. Eur J Clin Microbiol Infect Dis 25: 120–122PubMedCrossRef
36.
Zurück zum Zitat Resch B, Nuijten MJ, Lebmeier M et al. (2006) The cost-effectiveness of palivizumab in Austria. Value Health 9: A94 Resch B, Nuijten MJ, Lebmeier M et al. (2006) The cost-effectiveness of palivizumab in Austria. Value Health 9: A94
37.
Zurück zum Zitat Sampalis JS (2003) Morbidity and mortality after RSV-associated hospitalizations among premature Canadian infants. J Pediatr 143: S150–156PubMedCrossRef Sampalis JS (2003) Morbidity and mortality after RSV-associated hospitalizations among premature Canadian infants. J Pediatr 143: S150–156PubMedCrossRef
38.
Zurück zum Zitat Schauer U, Hoffjan S, Bittscheidt J et al. (2002) RSV bronchiolitis and risk of wheeze and allergic sensitisation in the first year of life. Eur Respir J 20:1277–1283PubMedCrossRef Schauer U, Hoffjan S, Bittscheidt J et al. (2002) RSV bronchiolitis and risk of wheeze and allergic sensitisation in the first year of life. Eur Respir J 20:1277–1283PubMedCrossRef
39.
Zurück zum Zitat Schwarze J, O’Donnell DR, Rohwedder A et al. (2004) Latency and persistence of respiratory syncytial virus despite T cell immunity. Am J Respir Crit Care Med 169: 801–805PubMedCrossRef Schwarze J, O’Donnell DR, Rohwedder A et al. (2004) Latency and persistence of respiratory syncytial virus despite T cell immunity. Am J Respir Crit Care Med 169: 801–805PubMedCrossRef
40.
Zurück zum Zitat Sigurs N, Bjarnason R, Sigurbergsson F et al. (2000) Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 161: 1501–1507PubMed Sigurs N, Bjarnason R, Sigurbergsson F et al. (2000) Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med 161: 1501–1507PubMed
41.
Zurück zum Zitat Sigurs N, Gustafsson PM, Bjarnason R et al. (2005) Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 171: 137–141PubMedCrossRef Sigurs N, Gustafsson PM, Bjarnason R et al. (2005) Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 171: 137–141PubMedCrossRef
42.
Zurück zum Zitat Simoes EAF, Groothuis JR, Carbonell-Estrany X et al., and the Palivizumab Long-Term Respiratory Outcomes Study Group (2007) Palivizumab prophylaxis, respiratory syncytial virus, and subsequent recurrent wheezing. J Pediatr 151: 34–42PubMedCrossRef Simoes EAF, Groothuis JR, Carbonell-Estrany X et al., and the Palivizumab Long-Term Respiratory Outcomes Study Group (2007) Palivizumab prophylaxis, respiratory syncytial virus, and subsequent recurrent wheezing. J Pediatr 151: 34–42PubMedCrossRef
43.
Zurück zum Zitat Stein RT, Sherrill D, Morgan WJ et al. (1999) Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 354: 541–545PubMedCrossRef Stein RT, Sherrill D, Morgan WJ et al. (1999) Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet 354: 541–545PubMedCrossRef
44.
Zurück zum Zitat Sznajder M, Stheneur C, Albonico V et al.; General Pediatrics Group of the French Society of Pediatrics (2005) Respiratory development of 5- to 6-year-old children experiencing a first bronchiolitis episode before age one. Allergy Immunol 37: 392–396 Sznajder M, Stheneur C, Albonico V et al.; General Pediatrics Group of the French Society of Pediatrics (2005) Respiratory development of 5- to 6-year-old children experiencing a first bronchiolitis episode before age one. Allergy Immunol 37: 392–396
45.
Zurück zum Zitat Thomas NJ, Hollenbeak CS, Ceneviva GD et al. (2007) Palivizumab prophylaxis to prevent respiratory syncytial virus mortality after pediatric bone marrow transplantation: a decision tree model. J Pediatr Hematol Oncol 29: 227–232PubMedCrossRef Thomas NJ, Hollenbeak CS, Ceneviva GD et al. (2007) Palivizumab prophylaxis to prevent respiratory syncytial virus mortality after pediatric bone marrow transplantation: a decision tree model. J Pediatr Hematol Oncol 29: 227–232PubMedCrossRef
46.
Zurück zum Zitat Tortorolo L, Langer A, Polidori G et al. (2005) Neurotrophin overexpression in lower airways of infants with respiratory syncytial virus infection. Am J Respir Crit Care Med 172: 233–237PubMedCrossRef Tortorolo L, Langer A, Polidori G et al. (2005) Neurotrophin overexpression in lower airways of infants with respiratory syncytial virus infection. Am J Respir Crit Care Med 172: 233–237PubMedCrossRef
47.
Zurück zum Zitat Van Ewijk BE, Van der Zalm MM, Wolfs TFW et al. (2005) Viral respiratory infections in cystic fibrosis. J Cyst Fibros 4: 31–36CrossRef Van Ewijk BE, Van der Zalm MM, Wolfs TFW et al. (2005) Viral respiratory infections in cystic fibrosis. J Cyst Fibros 4: 31–36CrossRef
48.
Zurück zum Zitat Van Ewijk BE, Wolfs TFW, Aerts PC et al. (2007) RSV mediates Pseudomonas aeruginosa binding to cystic fibrosis and normal epithelial cells. Pediatr Res 61: 398–403CrossRef Van Ewijk BE, Wolfs TFW, Aerts PC et al. (2007) RSV mediates Pseudomonas aeruginosa binding to cystic fibrosis and normal epithelial cells. Pediatr Res 61: 398–403CrossRef
49.
Zurück zum Zitat Van Woensel JBM, Kimpen JLL, Sprikkelman AB et al. (2000) Long-term effects of prednisolone in the acute phase of bronchiolitis caused by respiratory syncytial virus. Pediatr Pulmonol 30: 92–96CrossRef Van Woensel JBM, Kimpen JLL, Sprikkelman AB et al. (2000) Long-term effects of prednisolone in the acute phase of bronchiolitis caused by respiratory syncytial virus. Pediatr Pulmonol 30: 92–96CrossRef
50.
Zurück zum Zitat Wat D, Doull I (2003) Respiratory virus infections in cystic fibrosis. Paediatr Respir Rev 4: 172–177PubMedCrossRef Wat D, Doull I (2003) Respiratory virus infections in cystic fibrosis. Paediatr Respir Rev 4: 172–177PubMedCrossRef
51.
Zurück zum Zitat Wenzel SE, Gibbs RL, Lehr MV et al. (2002) Respiratory outcome in high-risk children 7 to 10 years after prophylaxis with respiratory syncytial virus immunoglobulin. Am J Med 112: 627–633PubMedCrossRef Wenzel SE, Gibbs RL, Lehr MV et al. (2002) Respiratory outcome in high-risk children 7 to 10 years after prophylaxis with respiratory syncytial virus immunoglobulin. Am J Med 112: 627–633PubMedCrossRef
52.
Zurück zum Zitat Wilkesmann A, Ammann RA, Schildgen O et al., and the DSM RSV Ped Study Group (2007) Hospitalized children with respiratory syncytial virus infection and neuromuscular impairment face an increased risk of a complicated course. Pediatr Infect Dis J 26: 485–491PubMedCrossRef Wilkesmann A, Ammann RA, Schildgen O et al., and the DSM RSV Ped Study Group (2007) Hospitalized children with respiratory syncytial virus infection and neuromuscular impairment face an increased risk of a complicated course. Pediatr Infect Dis J 26: 485–491PubMedCrossRef
Metadaten
Titel
Konsensuspapier zur Prophylaxe der RSV-Infektion mit Palivizumab und Post-RSV-Atemwegserkrankung
verfasst von
Österreichische Gesellschaft für Kinder- und Jugendheilkunde (ÖGKJ)
Publikationsdatum
01.04.2008
Verlag
Springer-Verlag
Erschienen in
Monatsschrift Kinderheilkunde / Ausgabe 4/2008
Print ISSN: 0026-9298
Elektronische ISSN: 1433-0474
DOI
https://doi.org/10.1007/s00112-008-1722-y

Weitere Artikel der Ausgabe 4/2008

Monatsschrift Kinderheilkunde 4/2008 Zur Ausgabe

Durch übermäßige Internetnutzung wird oft die Schule verpasst

Häufige Fehlzeiten in der Schule können durch physische und psychische Probleme verursacht werden. Wie in einer Studie aus Finnland nun belegt wird, führt auch die exzessive Nutzung des Internets gehäuft zu Abwesenheiten.

Kinder mit anhaltender Sinusitis profitieren häufig von Antibiotika

30.04.2024 Rhinitis und Sinusitis Nachrichten

Persistieren Sinusitisbeschwerden bei Kindern länger als zehn Tage, ist eine Antibiotikatherapie häufig gut wirksam: Ein Therapieversagen ist damit zu über 40% seltener zu beobachten als unter Placebo.

Neuer Typ-1-Diabetes bei Kindern am Wochenende eher übersehen

23.04.2024 Typ-1-Diabetes Nachrichten

Wenn Kinder an Werktagen zum Arzt gehen, werden neu auftretender Typ-1-Diabetes und diabetische Ketoazidosen häufiger erkannt als bei Arztbesuchen an Wochenenden oder Feiertagen.

Neue Studienergebnisse zur Myopiekontrolle mit Atropin

22.04.2024 Fehlsichtigkeit Nachrichten

Augentropfen mit niedrig dosiertem Atropin können helfen, das Fortschreiten einer Kurzsichtigkeit bei Kindern zumindest zu verlangsamen, wie die Ergebnisse einer aktuellen Studie mit verschiedenen Dosierungen zeigen.

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.