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Erschienen in:

25.09.2018 | Main topic

Leadless pacing

verfasst von: PD Dr. J. Sperzel, C. Hamm, A. Hain

Erschienen in: Herz | Ausgabe 7/2018

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Abstract

Leadless self-contained intracardiac pacemakers were developed with the aim of abolishing the short- and long-term risk of lead- and pocket-related complications associated with transvenous devices. Leadless pacemakers promise minimally invasive procedures, long battery lives, and small amounts of foreign materials in the body. Experiences with the pioneering single-chamber devices have provided reasons for optimism about the future of the leadless concept. In the future, as more patients receive and live longer with implantable devices, the total risk of procedure- and lead-related complications is expected to increase, adding a sense of urgency to the need for leadless alternatives to transvenous pacemakers. This review surveys the performance of currently available leadless pacemakers as well as emerging new innovative adaptations and applications of the leadless concept.

Mittal T (2005) Pacemakers—A journey through the years. Indian J Thorac Cardiovasc Surg 21:236–249. https://doi.org/10.1007/s12055-005-0060-0 CrossRef

Kirkfeldt RE, Johansen JB, Nohr EA et al (2011) Risk factors for lead complications in cardiac pacing: a population-based cohort study of 28,860 Danish patients. Heart Rhythm 8:1622–1628. https://doi.org/10.1016/j.hrthm.2011.04.014 CrossRefPubMed

Udo EO, Zuithoff NPA, van Hemel NM et al (2012) Incidence and predictors of short- and long-term complications in pacemaker therapy: the FOLLOWPACE study. Heart Rhythm 9:728–735. https://doi.org/10.1016/j.hrthm.2011.12.014 CrossRefPubMed

Kirkfeldt RE, Johansen JB, Nohr EA et al (2014) Complications after cardiac implantable electronic device implantations: an analysis of a complete, nationwide cohort in Denmark. Eur Heart J 35:1186–1194. https://doi.org/10.1093/eurheartj/eht511 CrossRefPubMed

Ponikowski P, Voors AA, Anker SD et al (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 37:2129–2200. https://doi.org/10.1093/eurheartj/ehw128 CrossRefPubMed

Ubrich R, Kreiser K, Sinnecker D, Schneider S (2016) Magnetic resonance imaging at 1.5-T in a patient with implantable leadless pacemaker. Eur Heart J 37:2441–2441. https://doi.org/10.1093/eurheartj/ehv360 CrossRefPubMed

Cay S, Ozeke O, Ozcan F et al (2016) An important advantage of the leadless pacemakers: magnetic resonance imaging compatibility. Europace 18(628):1–629. https://doi.org/10.1093/europace/euv246 CrossRef

Reddy VY, Exner DV, Cantillon DJ et al (2015) Percutaneous implantation of an entirely intracardiac leadless pacemaker. N Engl J Med 373:1125–1135. https://doi.org/10.1056/NEJMoa1507192 CrossRefPubMed

Reddy VY, Knops RE, Sperzel J et al (2014) Permanent leadless cardiac pacing: results of the LEADLESS trial. Circulation 129:1466–1471. https://doi.org/10.1161/CIRCULATIONAHA.113.006987 CrossRefPubMed

10.

Sperzel J, Defaye P, Delnoy P‑P et al (2018) Primary safety results from the LEADLESS Observational Study. Europace. https://doi.org/10.1093/europace/eux359 CrossRefPubMed

11.

Reynolds D, Duray GZ, Omar R et al (2016) A leadless intracardiac transcatheter pacing system. N Engl J Med 374:533–541. https://doi.org/10.1056/NEJMoa1511643 CrossRefPubMed

12.

Roberts PR, Clementy N, Al Samadi F et al (2017) A leadless pacemaker in the real-world setting: the micra transcatheter pacing system post-approval registry. Heart Rhythm 14:1375–1379. https://doi.org/10.1016/j.hrthm.2017.05.017 CrossRefPubMed

13.

Tjong FVY, Reddy VY (2017) Permanent leadless cardiac pacemaker therapy: a comprehensive review. Circulation 135:1458–1470. https://doi.org/10.1161/CIRCULATIONAHA.116.025037 CrossRefPubMed

14.

Wilkoff BL, Bello D, Taborsky M et al (2011) Magnetic resonance imaging in patients with a pacemaker system designed for the magnetic resonance environment. Heart Rhythm 8:65–73. https://doi.org/10.1016/j.hrthm.2010.10.002 CrossRefPubMed

15.

Knops RE, Brouwer TF, Barr CS et al (2016) The learning curve associated with the introduction of the subcutaneous implantable defibrillator. Europace 18:1010–1015. https://doi.org/10.1093/europace/euv299 CrossRefPubMed

16.

Minha S, Waksman R, Satler LP et al (2016) Learning curves for transfemoral transcatheter aortic valve replacement in the PARTNER-I trial: success and safety. Catheter Cardiovasc Interv 87:165–175. https://doi.org/10.1002/ccd.26121 CrossRefPubMed

17.

El-Chami M, Kowal RC, Soejima K et al (2017) Impact of operator experience and training strategy on procedural outcomes with leadless pacing: Insights from the Micra Transcatheter Pacing Study. Pacing Clin Electrophysiol 40:834–842. https://doi.org/10.1111/pace.13094 CrossRefPubMed

18.

Duray GZ, Ritter P, El-Chami M et al (2017) Long-term performance of a transcatheter pacing system: 12-Month results from the Micra Transcatheter Pacing Study. Heart Rhythm 14:702–709. https://doi.org/10.1016/j.hrthm.2017.01.035 CrossRefPubMed

19.

Tjong FVY, Knops RE, Udo EO et al (2018) Leadless pacemaker versus transvenous single-chamber pacemaker therapy: a propensity score-matched analysis. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2018.04.027 CrossRefPubMed

20.

Lakkireddy D, Knops R, Atwater B et al (2017) A worldwide experience of the management of battery failures and chronic device retrieval of the Nanostim leadless pacemaker. Heart Rhythm 14:1756–1763. https://doi.org/10.1016/j.hrthm.2017.07.004 CrossRefPubMed

21.

Richter S, Döring M, Ebert M et al (2018) Battery malfunction of a leadless cardiac pacemaker—a worrisome single-center experience. Circulation. https://doi.org/10.1161/CIRCULATIONAHA.117.033371 CrossRefPubMed

22.

Beurskens NEG, Tjong FVY, Quast A‑FBE, Knops RE (2018) Successful replacement of the longest worldwide in situ nanostim leadless cardiac pacemaker for a micra transcatheter pacing system. J Interv Card Electrophysiol 51:161–162. https://doi.org/10.1007/s10840-017-0310-2 CrossRefPubMedPubMedCentral

23.

Grubman E, Ritter P, Ellis CR et al (2017) To retrieve, or not to retrieve: system revisions with the micra transcatheter pacemaker. Heart Rhythm 14:1801–1806. https://doi.org/10.1016/j.hrthm.2017.07.015 CrossRefPubMed

24.

Omdahl P, Eggen MD, Bonner MD et al (2016) Right ventricular anatomy can accommodate multiple micra transcatheter pacemakers. Pacing Clin Electrophysiol 39:393–397. https://doi.org/10.1111/pace.12804 CrossRefPubMedPubMedCentral

25.

Crotti N (2018) Abbott is developing a dual-chamber leadless pacemaker. Med Des Outsourcing. https://www.medicaldesignandoutsourcing.com/abbott-is-developing-a-dual-chamber-leadless-pacer/. Accessed 2 Aug 2018

26.

Bereuter L, Gysin M, Kueffer T et al (2018) 38Leadless cardiac dual-chamber pacing. Ep Eur 20:i1–i1. https://doi.org/10.1093/europace/euy015 CrossRef

27.

Mihalcz A, Kassai I, Geller L, Szili-Török T (2014) Alternative techniques for left ventricular pacing in cardiac resynchronization therapy. Pacing Clin Electrophysiol 37:255–261. https://doi.org/10.1111/pace.12320 CrossRefPubMed

28.

Reddy VY, Miller MA, Neuzil P et al (2017) Cardiac resynchronization therapy with wireless left ventricular endocardial pacing: the SELECT-LV study. J Am Coll Cardiol 69:2119–2129. https://doi.org/10.1016/j.jacc.2017.02.059 CrossRefPubMed

29.

Auricchio A, Delnoy P‑P, Butter C et al (2014) Feasibility, safety, and short-term outcome of leadless ultrasound-based endocardial left ventricular resynchronization in heart failure patients: results of the wireless stimulation endocardially for CRT (WiSE-CRT) study. Europace 16:681–688. https://doi.org/10.1093/europace/eut435 CrossRefPubMed

30.

van Rees JB, de Bie MK, Thijssen J et al (2011) Implantation-related complications of implantable cardioverter-defibrillators and cardiac resynchronization therapy devices: a systematic review of randomized clinical trials. J Am Coll Cardiol 58:995–1000. https://doi.org/10.1016/j.jacc.2011.06.007 CrossRefPubMed

31.

Maisel WH, Kramer DB (2008) Implantable cardioverter-defibrillator lead performance. Circulation 117:2721–2723. https://doi.org/10.1161/CIRCULATIONAHA.108.776807 CrossRefPubMed

32.

Bardy GH, Smith WM, Hood MA et al (2010) An entirely subcutaneous implantable cardioverter-defibrillator. N Engl J Med 363:36–44. https://doi.org/10.1056/NEJMoa0909545 CrossRefPubMed

33.

Burke MC, Gold MR, Knight BP et al (2015) Safety and efficacy of the totally subcutaneous implantable defibrillator: 2‑year results from a pooled analysis of the IDE study and EFFORTLESS registry. J Am Coll Cardiol 65:1605–1615. https://doi.org/10.1016/j.jacc.2015.02.047 CrossRefPubMed

34.

Boersma L, Barr C, Knops R et al (2017) Implant and midterm outcomes of the subcutaneous implantable cardioverter-defibrillator registry: the EFFORTLESS study. J Am Coll Cardiol 70:830–841. https://doi.org/10.1016/j.jacc.2017.06.040 CrossRefPubMed

35.

Priori SG, Blomström-Lundqvist C, Mazzanti A et al (2015) 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J 36:2793–2867. https://doi.org/10.1093/eurheartj/ehv316 CrossRefPubMed

36.

Al-Khatib SM, Stevenson WG, Ackerman MJ et al (2017) 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. https://doi.org/10.1161/CIR.0000000000000549 CrossRefPubMedPubMedCentral

37.

Markewitz A (2011) Annual report 2009 of the German cardiac pacemaker registry: federal section pacemaker and AQUA – institute for applied quality improvement and research in health Ltd. Herzschrittmacherther Elektrophysiol 22:259–280. https://doi.org/10.1007/s00399-011-0149-7 CrossRefPubMed

38.

Quast A‑FBE, Tjong FVY, Koop BE et al (2018) Device orientation of a leadless pacemaker and subcutaneous implantable cardioverter-defibrillator in canine and human subjects and the effect on intrabody communication. Europace. https://doi.org/10.1093/europace/euy019 CrossRefPubMed

Titel: Leadless pacing
verfasst von: PD Dr. J. Sperzel
C. Hamm
A. Hain
Publikationsdatum: 25.09.2018
Verlag: Springer Medizin
Erschienen in: Herz / Ausgabe 7/2018
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI: https://doi.org/10.1007/s00059-018-4752-9

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