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07.03.2018 | Original Article

Light-emitting diode therapy (photobiomodulation) effects on oxygen uptake and cardiac output dynamics during moderate exercise transitions: a randomized, crossover, double-blind, and placebo-controlled study

verfasst von: Thomas Beltrame, Cleber Ferraresi, Nivaldo Antonio Parizotto, Vanderlei Salvador Bagnato, Richard L. Hughson

Erschienen in: Lasers in Medical Science | Ausgabe 5/2018

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Abstract

Light-emitting diodes (LEDs) might have a beneficial impact on cytochrome-c oxidase enzyme activity. Thus, it was hypothesized that photobiomodulation by light-emitting diode therapy (LEDT) could influence aerobic metabolism dynamics. Possible LEDT-mediated aerobic improvements were investigated mainly by a precise characterization of the pulmonary O₂ uptake dynamics during moderate exercise transitions. Eight healthy young adults were enrolled in this randomized, double-blind, placebo-controlled, crossover study. A multi-diode array of LEDs was used for muscular pre-conditioning 30 min and 6 h before exercise testing. Pulmonary O₂ uptake, carbon dioxide output, cardiac output, heart rate, stroke volume, and total arteriovenous oxygen difference dynamics were evaluated by frequency domain analysis. Comparisons revealed no statistical (p > 0.05) differences between LEDT and placebo, suggesting no significant changes in aerobic system dynamics. These results challenge earlier publications that reported changes in pulmonary O₂ uptake during incremental exercise until exhaustion after LEDT. Perhaps, increments in peak pulmonary O₂ uptake after LEDT may be a consequence of higher exercise tolerance caused by non-aerobic-related factors as opposed to an improved aerobic response.

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Titel: Light-emitting diode therapy (photobiomodulation) effects on oxygen uptake and cardiac output dynamics during moderate exercise transitions: a randomized, crossover, double-blind, and placebo-controlled study
verfasst von: Thomas Beltrame
Cleber Ferraresi
Nivaldo Antonio Parizotto
Vanderlei Salvador Bagnato
Richard L. Hughson
Publikationsdatum: 07.03.2018
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 5/2018
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-018-2473-1

Springer Medizin

Abstract

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