Skip to main content
Erschienen in: Der Hautarzt 12/2012

01.12.2012 | Leitthema

Hauterkrankungen beim geriatrischen Patienten

Epidemiologische Daten

verfasst von: E. Makrantonaki, A.I. Liakou, R. Eckardt, M. Zens, E. Steinhagen-Thiessen, Prof. Dr. C.C. Zouboulis

Erschienen in: Die Dermatologie | Ausgabe 12/2012

Einloggen, um Zugang zu erhalten

Zusammenfassung

In den letzten Jahren hat die Inzidenz altersassoziierter Hauterkrankungen, insbesondere entzündlicher Dermatosen, Autoimmunerkrankungen, Tumoren und paraneoplastischer Syndrome progredient zugenommen. Diese bedeutende Entwicklung liegt in einer erhöhten Früh- und lebenslangen UV-Exposition sowie im demographischen Alterungsprozess begründet. Um den demographischen Wandel zukünftig als Chance zu erleben, sind ein besseres Verständnis der Pathomechanismen dieser speziellen Erkrankungen sowie eine frühzeitige Diagnose und Therapie essenziell. Darüber hinaus muss die breite Öffentlichkeit für diesen Themenkomplex sensibilisiert und der Patient individuell aufgeklärt werden. Diese Strategie beinhaltet frühzeitige, prophylaktische Maßnahmen und eine konsequente Überwachung von Hochrisikogruppen. In der vorliegenden Arbeit wird die erwähnte Beziehung zwischen Hautalterung und der Epidemiologie assoziierter Erkrankungen unter Berücksichtigung der Risikofaktoren im Detail dargestellt.
Literatur
1.
Zurück zum Zitat United Nations (Hrsg) (2007) World population prospects the 2006 revision highlights. Department of economic and social affairs population division. United Nations Publications, New York United Nations (Hrsg) (2007) World population prospects the 2006 revision highlights. Department of economic and social affairs population division. United Nations Publications, New York
3.
Zurück zum Zitat Jazwinski SM (1999) The RAS genes: a homeostatic device in Saccharomyces cerevisiae longevity. Neurobiol Aging 20(5):471–478PubMedCrossRef Jazwinski SM (1999) The RAS genes: a homeostatic device in Saccharomyces cerevisiae longevity. Neurobiol Aging 20(5):471–478PubMedCrossRef
4.
Zurück zum Zitat Oeppen J, Vaupel JW (2002) Demography. Broken limits to life expectancy. Science 296(5570):1029–1031PubMedCrossRef Oeppen J, Vaupel JW (2002) Demography. Broken limits to life expectancy. Science 296(5570):1029–1031PubMedCrossRef
5.
Zurück zum Zitat Fisher GJ, Kang S et al (2002) Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138(11):1462–1470PubMedCrossRef Fisher GJ, Kang S et al (2002) Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138(11):1462–1470PubMedCrossRef
6.
Zurück zum Zitat Evelson P, Ordonez CP et al (1997) Oxidative stress and in vivo chemiluminescence in mouse skin exposed to UVA radiation. J Photochem Photobiol 38(2–3):215–219 Evelson P, Ordonez CP et al (1997) Oxidative stress and in vivo chemiluminescence in mouse skin exposed to UVA radiation. J Photochem Photobiol 38(2–3):215–219
7.
Zurück zum Zitat Podda M, Traber MG et al (1998) UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin. Free Radic Biol Med 24(1):55–65PubMedCrossRef Podda M, Traber MG et al (1998) UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin. Free Radic Biol Med 24(1):55–65PubMedCrossRef
8.
Zurück zum Zitat Kohen R (1999) Skin antioxidants: their role in aging and in oxidative stress-new approaches for their evaluation. Biomed Pharmacother 53(4):181–192PubMedCrossRef Kohen R (1999) Skin antioxidants: their role in aging and in oxidative stress-new approaches for their evaluation. Biomed Pharmacother 53(4):181–192PubMedCrossRef
9.
Zurück zum Zitat Rittie L, Fisher GJ (2002) UV-light-induced signal cascades and skin aging. Ageing Res Rev 1(4):705–720PubMedCrossRef Rittie L, Fisher GJ (2002) UV-light-induced signal cascades and skin aging. Ageing Res Rev 1(4):705–720PubMedCrossRef
10.
Zurück zum Zitat Uitto J (1986) Connective tissue biochemistry of the aging dermis. Age-related alterations in collagen and elastin. Dermatol Clin 4(3):433–446PubMed Uitto J (1986) Connective tissue biochemistry of the aging dermis. Age-related alterations in collagen and elastin. Dermatol Clin 4(3):433–446PubMed
11.
Zurück zum Zitat Ashcroft GS, Herrick SE et al (1997) Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA. J Pathol 183(2):169–176PubMedCrossRef Ashcroft GS, Herrick SE et al (1997) Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA. J Pathol 183(2):169–176PubMedCrossRef
12.
Zurück zum Zitat Eaglstein WH (1989) Wound healing and aging. Clin Geriatr Med 5(1):183–188PubMed Eaglstein WH (1989) Wound healing and aging. Clin Geriatr Med 5(1):183–188PubMed
13.
Zurück zum Zitat Zouboulis CC, Makrantonaki E (2011) Clinical aspects and molecular diagnostics of skin aging. Clin Dermatol 29:3–14PubMedCrossRef Zouboulis CC, Makrantonaki E (2011) Clinical aspects and molecular diagnostics of skin aging. Clin Dermatol 29:3–14PubMedCrossRef
14.
Zurück zum Zitat Arnaud L, Mathian A, Boddaert J, Amoura Z (2012) Late-onset systemic lupus erythematosus: epidemiology, diagnosis and treatment. Drugs Aging 29(3):181–189PubMedCrossRef Arnaud L, Mathian A, Boddaert J, Amoura Z (2012) Late-onset systemic lupus erythematosus: epidemiology, diagnosis and treatment. Drugs Aging 29(3):181–189PubMedCrossRef
15.
Zurück zum Zitat Lalani S, Pope J, Leon F de et al (2010) Clinical features and prognosis of late-onset systemic lupus erythematosus: results from the 1000 faces of lupus study. J Rheumatol 37(1):38–44PubMedCrossRef Lalani S, Pope J, Leon F de et al (2010) Clinical features and prognosis of late-onset systemic lupus erythematosus: results from the 1000 faces of lupus study. J Rheumatol 37(1):38–44PubMedCrossRef
16.
Zurück zum Zitat Boddaert J, Huong DL, Amoura Z et al (2004) Late-onset systemic lupus erythematosus: a personal series of 47 patients and pooled analysis of 714 cases in the literature. Medicine (Baltimore) 83(6):348–359 Boddaert J, Huong DL, Amoura Z et al (2004) Late-onset systemic lupus erythematosus: a personal series of 47 patients and pooled analysis of 714 cases in the literature. Medicine (Baltimore) 83(6):348–359
17.
Zurück zum Zitat Ingen-Housz-Oro S, Alexandre M, Le Roux-Villet C et al (2012) Pemphigus in elderly adults: clinical presentation, treatment, and prognosis. J Am Geriatr Soc 60(6):1185–1187PubMedCrossRef Ingen-Housz-Oro S, Alexandre M, Le Roux-Villet C et al (2012) Pemphigus in elderly adults: clinical presentation, treatment, and prognosis. J Am Geriatr Soc 60(6):1185–1187PubMedCrossRef
18.
Zurück zum Zitat Langan SM, Smeeth L, Hubbard R et al (2008) Bullous pemphigoid and pemphigus vulgaris – incidence and mortality in the UK: population based cohort study. BMJ 337:a180PubMedCrossRef Langan SM, Smeeth L, Hubbard R et al (2008) Bullous pemphigoid and pemphigus vulgaris – incidence and mortality in the UK: population based cohort study. BMJ 337:a180PubMedCrossRef
19.
Zurück zum Zitat Kwon HH, Kwon IH, Youn JI (2012) Clinical study of psoriasis occurring over the age of 60 years: Is elderly-onset psoriasis a distinct subtype? Int J Dermatol 51(1):53–58PubMedCrossRef Kwon HH, Kwon IH, Youn JI (2012) Clinical study of psoriasis occurring over the age of 60 years: Is elderly-onset psoriasis a distinct subtype? Int J Dermatol 51(1):53–58PubMedCrossRef
20.
Zurück zum Zitat Ferrándiz C, Pujol RM, García-Patos V et al (2002) Psoriasis of early and late onset: a clinical and epidemiologic study from Spain. J Am Acad Dermatol 46(6):867–873PubMedCrossRef Ferrándiz C, Pujol RM, García-Patos V et al (2002) Psoriasis of early and late onset: a clinical and epidemiologic study from Spain. J Am Acad Dermatol 46(6):867–873PubMedCrossRef
21.
Zurück zum Zitat Piérard-Franchimont C, Piérard GE (2012) Drug-related psoriasis. Rev Med Liege 67(3):139–142PubMed Piérard-Franchimont C, Piérard GE (2012) Drug-related psoriasis. Rev Med Liege 67(3):139–142PubMed
22.
Zurück zum Zitat Bansal R, Tutrone WD, Weinberg JM (2002) Viral skin infections in the elderly: diagnosis and management. Drugs Aging 19(7):503–514PubMedCrossRef Bansal R, Tutrone WD, Weinberg JM (2002) Viral skin infections in the elderly: diagnosis and management. Drugs Aging 19(7):503–514PubMedCrossRef
23.
Zurück zum Zitat Weinberg JM, Scheinfeld NS (2003) Cutaneous infections in the elderly: diagnosis and management. Dermatol Ther 16(3):195–205PubMedCrossRef Weinberg JM, Scheinfeld NS (2003) Cutaneous infections in the elderly: diagnosis and management. Dermatol Ther 16(3):195–205PubMedCrossRef
24.
Zurück zum Zitat Weinberg JM, Vafaie J, Scheinfeld NS (2010) Skin infections in the elderly. Dermatol Clin 22(1):51–61 Weinberg JM, Vafaie J, Scheinfeld NS (2010) Skin infections in the elderly. Dermatol Clin 22(1):51–61
26.
Zurück zum Zitat Rabe E, Guex JJ, Puskas A et al (2012) Epidemiology of chronic venous disorders in geographically diverse populations: results from the Vein Consult Program. Int Angiol 31(2):105–115PubMed Rabe E, Guex JJ, Puskas A et al (2012) Epidemiology of chronic venous disorders in geographically diverse populations: results from the Vein Consult Program. Int Angiol 31(2):105–115PubMed
27.
Zurück zum Zitat Carpentier PH, Maricq HR, Biro C et al (2004) Prevalence, risk factors, and clinical patterns of chronic venous disorders of lower limbs: a population-based study in France. J Vasc Surg 40:650–659PubMedCrossRef Carpentier PH, Maricq HR, Biro C et al (2004) Prevalence, risk factors, and clinical patterns of chronic venous disorders of lower limbs: a population-based study in France. J Vasc Surg 40:650–659PubMedCrossRef
28.
Zurück zum Zitat Fowkes FG, Evans CJ, Lee AJ (2001) Prevalence and risk factors of chronic venous insufficiency. Angiology 52(1):5–15CrossRef Fowkes FG, Evans CJ, Lee AJ (2001) Prevalence and risk factors of chronic venous insufficiency. Angiology 52(1):5–15CrossRef
29.
Zurück zum Zitat Jawien A, Grzela T, Ochwat A (2003) Prevalence of chronic venous insufficiency in men and women in Poland: multicentre cross-sectional study in 40,095 patients. Phlebology 18:110–122CrossRef Jawien A, Grzela T, Ochwat A (2003) Prevalence of chronic venous insufficiency in men and women in Poland: multicentre cross-sectional study in 40,095 patients. Phlebology 18:110–122CrossRef
30.
Zurück zum Zitat Lozano FS, Masegosa A, Alvarez J et al (2009) Occurrence and management of chronic venous disease in primary health care in Spain. A comparison of DETECT-2006 with DETECT-2000. Int Angiol 28:62–67PubMed Lozano FS, Masegosa A, Alvarez J et al (2009) Occurrence and management of chronic venous disease in primary health care in Spain. A comparison of DETECT-2006 with DETECT-2000. Int Angiol 28:62–67PubMed
31.
Zurück zum Zitat Rabe E, Pannier-Fischer F, Bromen K et al (2003) Bonner Venenstudie der Deutschen Gesellschaft für Phlebologie – Epidemiologische Untersuchung zur Frage der Häufigkeit und Ausprägung von chronischen Venenkrankheiten in der städtischen und ländlichen Wohnbevölkerung. Phlebologie 32:1–14 Rabe E, Pannier-Fischer F, Bromen K et al (2003) Bonner Venenstudie der Deutschen Gesellschaft für Phlebologie – Epidemiologische Untersuchung zur Frage der Häufigkeit und Ausprägung von chronischen Venenkrankheiten in der städtischen und ländlichen Wohnbevölkerung. Phlebologie 32:1–14
32.
Zurück zum Zitat Eklöf B, Perrin M, Delis KT et al (2009) Updated terminology of chronic venous disorders: the VEIN-TERM transatlantic interdisciplinary consensus document. J Vasc Surg 49:498–501PubMedCrossRef Eklöf B, Perrin M, Delis KT et al (2009) Updated terminology of chronic venous disorders: the VEIN-TERM transatlantic interdisciplinary consensus document. J Vasc Surg 49:498–501PubMedCrossRef
33.
Zurück zum Zitat Nicolaides AN, Allegra C, Bergan J et al (2008) Management of chronic venous disorders of the lower limbs: guidelines according to scientific evidence. Int Angiol 27:1–59PubMed Nicolaides AN, Allegra C, Bergan J et al (2008) Management of chronic venous disorders of the lower limbs: guidelines according to scientific evidence. Int Angiol 27:1–59PubMed
34.
Zurück zum Zitat Kottner J, Wilborn D, Dassen T, Lahmann N (2009) The trend of pressure ulcer prevalence rates in German hospitals: results of seven crosssectional studies. J Tissue Viability 18:36–46PubMedCrossRef Kottner J, Wilborn D, Dassen T, Lahmann N (2009) The trend of pressure ulcer prevalence rates in German hospitals: results of seven crosssectional studies. J Tissue Viability 18:36–46PubMedCrossRef
35.
Zurück zum Zitat Theisen S, Drabik A, Stock S (2011) Pressure ulcers in older hospitalised patients and its impact on length of stay: a retrospective observational study. J Clin Nurs 21:380–387PubMedCrossRef Theisen S, Drabik A, Stock S (2011) Pressure ulcers in older hospitalised patients and its impact on length of stay: a retrospective observational study. J Clin Nurs 21:380–387PubMedCrossRef
36.
Zurück zum Zitat Iizaka S, Okuwa M, Sugama J, Sanada H (2010) The impact of malnutrition and nutrition-related factors on the development and severity of pressure ulcers in older patients receiving home care. Clinical Nutrition 29:47–53PubMedCrossRef Iizaka S, Okuwa M, Sugama J, Sanada H (2010) The impact of malnutrition and nutrition-related factors on the development and severity of pressure ulcers in older patients receiving home care. Clinical Nutrition 29:47–53PubMedCrossRef
37.
Zurück zum Zitat Goldberg LH, Mamelak AJ (2010) Review of actinic keratosis. Part I: etiology, epidemiology and clinical presentation. J Drugs Dermatol 9:1125–1132PubMed Goldberg LH, Mamelak AJ (2010) Review of actinic keratosis. Part I: etiology, epidemiology and clinical presentation. J Drugs Dermatol 9:1125–1132PubMed
38.
Zurück zum Zitat Schmitt JV, Miot HA (2012) Actinic keratosis: a clinical and epidemiological revision. An Bras Dermatol 87:425–434PubMedCrossRef Schmitt JV, Miot HA (2012) Actinic keratosis: a clinical and epidemiological revision. An Bras Dermatol 87:425–434PubMedCrossRef
39.
Zurück zum Zitat Traianou A, Ulrich M, Apalla Z et al (2012) Risk factors for actinic keratosis in eight European centres: a case-control study. Br Assoc Dermatologists 167(2):36–42CrossRef Traianou A, Ulrich M, Apalla Z et al (2012) Risk factors for actinic keratosis in eight European centres: a case-control study. Br Assoc Dermatologists 167(2):36–42CrossRef
40.
Zurück zum Zitat Bath-Hextall F, Leonardi-Bee J, Smith C et al (2007) Trends in incidence of skin basal cell carcinoma. Additional evidence from a UK primary care database study. Int J Cancer 121:2105–2108PubMedCrossRef Bath-Hextall F, Leonardi-Bee J, Smith C et al (2007) Trends in incidence of skin basal cell carcinoma. Additional evidence from a UK primary care database study. Int J Cancer 121:2105–2108PubMedCrossRef
41.
Zurück zum Zitat Flohil SC, Vries E de, Neumann HAM et al (2011) Incidence, prevalence, and future trends of primary basal cell carcinoma in the Netherlands. Acta Derm Venereol 91:24–30PubMed Flohil SC, Vries E de, Neumann HAM et al (2011) Incidence, prevalence, and future trends of primary basal cell carcinoma in the Netherlands. Acta Derm Venereol 91:24–30PubMed
42.
Zurück zum Zitat Birch-Johansen F, Jensen A, Mortensen L et al (2010) Trends in the incidence of nonmelanoma skin cancer in Denmark 1978–2007: rapid incidence increase among young Danish women. Int J Cancer 127:2190–2198PubMedCrossRef Birch-Johansen F, Jensen A, Mortensen L et al (2010) Trends in the incidence of nonmelanoma skin cancer in Denmark 1978–2007: rapid incidence increase among young Danish women. Int J Cancer 127:2190–2198PubMedCrossRef
43.
Zurück zum Zitat Karagas MR, Greenberg ER, Spencer SK et al (1999) Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA. New Hampshire Skin Cancer Study Group. Int J Cancer 81:555–559PubMedCrossRef Karagas MR, Greenberg ER, Spencer SK et al (1999) Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA. New Hampshire Skin Cancer Study Group. Int J Cancer 81:555–559PubMedCrossRef
44.
Zurück zum Zitat Buettner PG, Raasch BA (1998) Incidence rates of skin cancer in Townsville, Australia. Int J Cancer 78:587–593PubMedCrossRef Buettner PG, Raasch BA (1998) Incidence rates of skin cancer in Townsville, Australia. Int J Cancer 78:587–593PubMedCrossRef
45.
Zurück zum Zitat Chinem VP, Miot HA (2011) Epidemiology of basal cell carcinoma. An Bras Dermatol 86:292–305PubMedCrossRef Chinem VP, Miot HA (2011) Epidemiology of basal cell carcinoma. An Bras Dermatol 86:292–305PubMedCrossRef
46.
Zurück zum Zitat Trakatelli M, Ulrich C, Marmol V del et al (2007) Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: accurate and comparable data are needed for effective public health monitoring and interventions. Br J Dermatol 156(3):1–7PubMedCrossRef Trakatelli M, Ulrich C, Marmol V del et al (2007) Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: accurate and comparable data are needed for effective public health monitoring and interventions. Br J Dermatol 156(3):1–7PubMedCrossRef
47.
Zurück zum Zitat De Vries E, Micallef R, Brewster DH et al (2012) EPIDERM Group. Population-based estimates of the occurrence of multiple vs first primary basal cell carcinomas in 4 European regions. Arch Dermatol 148:347–354CrossRef De Vries E, Micallef R, Brewster DH et al (2012) EPIDERM Group. Population-based estimates of the occurrence of multiple vs first primary basal cell carcinomas in 4 European regions. Arch Dermatol 148:347–354CrossRef
49.
Zurück zum Zitat Schwartzberg JB, Elgart GW, Romanelli P et al (2005) Accuracy and predictors of basal cell carcinoma diagnosis. Dermatol Surg 31:534–537PubMedCrossRef Schwartzberg JB, Elgart GW, Romanelli P et al (2005) Accuracy and predictors of basal cell carcinoma diagnosis. Dermatol Surg 31:534–537PubMedCrossRef
50.
51.
Zurück zum Zitat Haliasos EC, Kerner M, Jaimes N et al (2012) Dermoscopy for the pediatric dermatologist, Part II: dermoscopy of genetic syndromes with cutaneous manifestations and pediatric vascular lesions. Pediatr Dermatol doi: 10.1111/j.1525-1470.2012.01874.x (Epub ahead of print) Haliasos EC, Kerner M, Jaimes N et al (2012) Dermoscopy for the pediatric dermatologist, Part II: dermoscopy of genetic syndromes with cutaneous manifestations and pediatric vascular lesions. Pediatr Dermatol doi: 10.1111/j.1525-1470.2012.01874.x (Epub ahead of print)
52.
Zurück zum Zitat Bergman R, Mercer A, Indelman M et al (2012) KID syndrome: histopathological, immunohistochemical and molecular analysis of precancerous and cancerous skin lesions. Br J Dermatol 166(2):455–457PubMedCrossRef Bergman R, Mercer A, Indelman M et al (2012) KID syndrome: histopathological, immunohistochemical and molecular analysis of precancerous and cancerous skin lesions. Br J Dermatol 166(2):455–457PubMedCrossRef
53.
Zurück zum Zitat Grossman D, Leffell DJ (2012) Squamous cell carcinoma. In: Goldsmith LA, Katz SI, Gilchrest BA et (Hrsg) Fitzpatrick’s dermatology in general medicine, 8 Aufl. McGraw-Hill, Columbus, S 1283–1294 Grossman D, Leffell DJ (2012) Squamous cell carcinoma. In: Goldsmith LA, Katz SI, Gilchrest BA et (Hrsg) Fitzpatrick’s dermatology in general medicine, 8 Aufl. McGraw-Hill, Columbus, S 1283–1294
54.
Zurück zum Zitat Lee LA, Huang CG, Liao CT et al (2012) Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One 7:e40767PubMedCrossRef Lee LA, Huang CG, Liao CT et al (2012) Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One 7:e40767PubMedCrossRef
55.
Zurück zum Zitat Marques-Silva L, Farias LC, Fraga CA et al (2012) HPV-16/18 detection does not affect the prognosis of head and neck squamous cell carcinoma in younger and older patients. Oncol Lett 3:945–949PubMed Marques-Silva L, Farias LC, Fraga CA et al (2012) HPV-16/18 detection does not affect the prognosis of head and neck squamous cell carcinoma in younger and older patients. Oncol Lett 3:945–949PubMed
56.
Zurück zum Zitat Arron ST, Jennings L, Nindl I et al (2011) Viral Working Group of the International Transplant Skin Cancer Collaborative (ITSCC) & Skin Care in Organ Transplant Patients, Europe (SCOPE). Viral oncogenesis and its role in nonmelanoma skin cancer. Br J Dermatol 164:1201–1213PubMedCrossRef Arron ST, Jennings L, Nindl I et al (2011) Viral Working Group of the International Transplant Skin Cancer Collaborative (ITSCC) & Skin Care in Organ Transplant Patients, Europe (SCOPE). Viral oncogenesis and its role in nonmelanoma skin cancer. Br J Dermatol 164:1201–1213PubMedCrossRef
57.
Zurück zum Zitat Andersson K, Michael KM, Luostarinen T et al (2012) Prospective study of human papillomavirus seropositivity and risk of nonmelanoma skin cancer. Am J Epidemiol 175:685–695PubMedCrossRef Andersson K, Michael KM, Luostarinen T et al (2012) Prospective study of human papillomavirus seropositivity and risk of nonmelanoma skin cancer. Am J Epidemiol 175:685–695PubMedCrossRef
58.
Zurück zum Zitat Allam E, Zhang W, Al-Shibani N et al (2011) Effects of cigarette smoke condensate on oral squamous cell carcinoma cells. Arch Oral Biol 56:1154–1161PubMedCrossRef Allam E, Zhang W, Al-Shibani N et al (2011) Effects of cigarette smoke condensate on oral squamous cell carcinoma cells. Arch Oral Biol 56:1154–1161PubMedCrossRef
59.
Zurück zum Zitat Ritchie SA, Patel MJ, Miller SJ (2012) Therapeutic options to decrease actinic keratosis and squamous cell carcinoma incidence and progression in solid organ transplant recipients: a practical approach. Dermatol Surg 38(10):1604–1621PubMedCrossRef Ritchie SA, Patel MJ, Miller SJ (2012) Therapeutic options to decrease actinic keratosis and squamous cell carcinoma incidence and progression in solid organ transplant recipients: a practical approach. Dermatol Surg 38(10):1604–1621PubMedCrossRef
60.
Zurück zum Zitat Rüegg CP, Graf N, Mühleisen B et al (2012) Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients. J Am Acad Dermatol [Epub ahead of print] Rüegg CP, Graf N, Mühleisen B et al (2012) Squamous cell carcinoma of the skin induces considerable sustained cost of care in organ transplant recipients. J Am Acad Dermatol [Epub ahead of print]
61.
Zurück zum Zitat Chamberlain AJ, Fritschi L, Giles GG et al (2002) Nodular type and older age as the most significant associations of thick melanoma in Victoria, Australia. Arch Dermatol 138:609–614PubMedCrossRef Chamberlain AJ, Fritschi L, Giles GG et al (2002) Nodular type and older age as the most significant associations of thick melanoma in Victoria, Australia. Arch Dermatol 138:609–614PubMedCrossRef
62.
Zurück zum Zitat Lasithiotakis KG, Leiter U, Gorkievicz R et al (2006) The incidence and mortality of cutaneous melanoma in southern Germany: trends by anatomic site and pathologic characteristics, 1976–2003. Cancer 107:1331–1339PubMedCrossRef Lasithiotakis KG, Leiter U, Gorkievicz R et al (2006) The incidence and mortality of cutaneous melanoma in southern Germany: trends by anatomic site and pathologic characteristics, 1976–2003. Cancer 107:1331–1339PubMedCrossRef
63.
Zurück zum Zitat Chang AE, Karnell LH, Menck HR (1998) The national cancer data base report on cutaneous and noncutaneous melanoma: a summary of 84.836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83:1664–1678PubMedCrossRef Chang AE, Karnell LH, Menck HR (1998) The national cancer data base report on cutaneous and noncutaneous melanoma: a summary of 84.836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society. Cancer 83:1664–1678PubMedCrossRef
64.
Zurück zum Zitat Morris BT, Sober AJ (1986) Cutaneous malignant melanoma in the older patient. Dermatol Clin 4:473–480PubMed Morris BT, Sober AJ (1986) Cutaneous malignant melanoma in the older patient. Dermatol Clin 4:473–480PubMed
65.
Zurück zum Zitat Keefe M, White JE, Perkins P (1990) Nodular melanomas in the over 50 age group the next target for health education. Br J Dermatol 123(37):59CrossRef Keefe M, White JE, Perkins P (1990) Nodular melanomas in the over 50 age group the next target for health education. Br J Dermatol 123(37):59CrossRef
66.
Zurück zum Zitat Kolb GF (2002) Bösartige Erkrankungen im Alter – Der alte Tumorpatient. Internist 43:959–964PubMedCrossRef Kolb GF (2002) Bösartige Erkrankungen im Alter – Der alte Tumorpatient. Internist 43:959–964PubMedCrossRef
68.
Zurück zum Zitat Stone SP, Buescher LS (2005) Life-threatening paraneoplastic cutaneous syndromes. Clin Dermatol 23(3):301–306PubMedCrossRef Stone SP, Buescher LS (2005) Life-threatening paraneoplastic cutaneous syndromes. Clin Dermatol 23(3):301–306PubMedCrossRef
69.
Zurück zum Zitat Abreu Velez AM, Howard MS (2010) Diagnosis and treatment of cutaneous paraneoplastic disorders. Dermatol Ther 23(6):662–675CrossRef Abreu Velez AM, Howard MS (2010) Diagnosis and treatment of cutaneous paraneoplastic disorders. Dermatol Ther 23(6):662–675CrossRef
Metadaten
Titel
Hauterkrankungen beim geriatrischen Patienten
Epidemiologische Daten
verfasst von
E. Makrantonaki
A.I. Liakou
R. Eckardt
M. Zens
E. Steinhagen-Thiessen
Prof. Dr. C.C. Zouboulis
Publikationsdatum
01.12.2012
Verlag
Springer-Verlag
Erschienen in
Die Dermatologie / Ausgabe 12/2012
Print ISSN: 2731-7005
Elektronische ISSN: 2731-7013
DOI
https://doi.org/10.1007/s00105-012-2466-0

Weitere Artikel der Ausgabe 12/2012

Der Hautarzt 12/2012 Zur Ausgabe

Panorama Dermatologische Praxis

Panorama Dermatologische Praxis

Leitthema

Geriatrie

CME Zertifizierte Fortbildung

Prinzipien der Steroidtherapie

Leitlinien kompakt für die Dermatologie

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Studienlage spricht für Isotretinoin zur Rosazea-Therapie

23.05.2024 Rosazea Nachrichten

Isotretinoin wird off-label zur Behandlung von Rosazea eingesetzt. Wie solide die Evidenz dafür ist, wurde jetzt in einem systematischen Review überprüft.

So sicher sind Tattoos: Neue Daten zur Risikobewertung

22.05.2024 Melanom Nachrichten

Das größte medizinische Problem bei Tattoos bleiben allergische Reaktionen. Melanome werden dadurch offensichtlich nicht gefördert, die Farbpigmente könnten aber andere Tumoren begünstigen.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Riesenzellarteriitis: 15% der Patienten sind von okkulter Form betroffen

16.05.2024 Riesenzellarteriitis Nachrichten

In einer retrospektiven Untersuchung haben Forschende aus Belgien und den Niederlanden die okkulte Form der Riesenzellarteriitis genauer unter die Lupe genommen. In puncto Therapie und Rezidivraten stellten sie keinen sehr großen Unterschied zu Erkrankten mit kranialen Symptomen fest.

Update Dermatologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.