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Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging 4/2007

01.04.2007 | Review Article

Stress-induced abnormalities in myocardial perfusion imaging that are not related to perfusion but are of diagnostic and prognostic importance

verfasst von: John P. Higgins, Johanna A. Higgins, Gethin Williams

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 4/2007

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Abstract

Introduction

Certain stress-induced ancillary findings on myocardial perfusion scintigraphy increase the likelihood that the patient has coronary artery disease (CAD); furthermore, among CAD patients, they indicate more severe and extensive disease, placing these patients at higher risk for future cardiac events. Indeed, in studies with no obvious perfusion defect yet with serious CAD—for example, balanced ischemia—it can be these high-risk findings that necessitate invasive intervention.

Discussion

Besides reversible perfusion defects, such findings include increased pulmonary radiotracer uptake, transient cavity dilatation, increased end-diastolic or end-systolic volume, decreased post-stress ejection fraction, and increased right ventricular tracer uptake on stress images. The pathophysiology underlying these findings is clearly different as they do not always occur together, and each independently predicts more severe and extensive CAD. In the current review, these findings are defined and their significance in diagnosing patients with suspected or known CAD is discussed.
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Metadaten
Titel
Stress-induced abnormalities in myocardial perfusion imaging that are not related to perfusion but are of diagnostic and prognostic importance
verfasst von
John P. Higgins
Johanna A. Higgins
Gethin Williams
Publikationsdatum
01.04.2007
Verlag
Springer-Verlag
Erschienen in
European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 4/2007
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-006-0293-1

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