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European Journal of Nuclear Medicine and Molecular Imaging

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01.07.2008 | Guidelines

EANM Dosimetry Committee series on standard operational procedures for pre-therapeutic dosimetry I: blood and bone marrow dosimetry in differentiated thyroid cancer therapy

verfasst von: Michael Lassmann, Heribert Hänscheid, Carlo Chiesa, Cecilia Hindorf, Glenn Flux, Markus Luster

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 7/2008

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Abstract

Introduction

The purpose of the EANM Dosimetry Committee Series on “Standard Operational Procedures for Pre-therapeutic Dosimetry” (SOP) is to provide advice to scientists and clinicians on how to perform pre-therapeutic and/or therapeutic patient-specific absorbed dose assessments.

Material and Methods

This particular SOP gives advice on how to tailor the therapeutic activity to be administered for systemic treatment of differentiated thyroid cancer (DTC) such that the absorbed dose to the blood does not exceed 2 Gy (a widely accepted limit for bone marrow toxicity). The methodology of blood-based dosimetry has been developed in the 1960s and refined in a series of international multi-centre trials in the framework of the introduction of new diagnostic and therapeutic tools, e.g. recombinant human thyroid-stimulating hormone in the management of DTC.

Conclusion

The intention is to guide the user through a series of measurements and calculations which the authors consider to be the best and most reproducible way at present.

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Titel: EANM Dosimetry Committee series on standard operational procedures for pre-therapeutic dosimetry I: blood and bone marrow dosimetry in differentiated thyroid cancer therapy
verfasst von: Michael Lassmann
Heribert Hänscheid
Carlo Chiesa
Cecilia Hindorf
Glenn Flux
Markus Luster
Publikationsdatum: 01.07.2008
Verlag: Springer-Verlag
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 7/2008
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-008-0761-x

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

EANM Dosimetry Committee series on standard operational procedures for pre-therapeutic dosimetry I: blood and bone marrow dosimetry in differentiated thyroid cancer therapy

Abstract

Introduction

Material and Methods

Conclusion

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Abstract

Introduction

Material and Methods

Conclusion

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