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Erschienen in: CardioVascular and Interventional Radiology 1/2016

01.01.2016 | Review

Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications

verfasst von: Fei Sun, Verónica Crisóstomo, Claudia Báez-Díaz, Francisco M. Sánchez

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 1/2016

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Abstract

Pathological features of benign prostatic hyperplasia (BPH) dictate various responses to prostatic artery embolization (PAE). Typically, BPH originates in the transition zone and periurethral region, where should be considered the primary target area in PAE procedures. Given that histological heterogeneity of components in hyperplasia nodules, epithelial or stromal, identifying the more responsive nodules to PAE will have clinical implications. Since some lower urinary tract symptoms (LUTS) in patients with BPH are usually related to bladder outlet obstruction-induced changes in bladder function rather than to outflow obstruction directly, proper selection of candidate patients prior to PAE is of great clinical importance. BPH is a typical chronic progressive condition, suggesting PAE could aim not only to relieve LUTS but also to delay or prevent the clinical progression. Awareness of the pathological background of BPH is essential for interventional radiologists to improve clinical outcomes and develop new treatment strategies in clinical practice of PAE.
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Metadaten
Titel
Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications
verfasst von
Fei Sun
Verónica Crisóstomo
Claudia Báez-Díaz
Francisco M. Sánchez
Publikationsdatum
01.01.2016
Verlag
Springer US
Erschienen in
CardioVascular and Interventional Radiology / Ausgabe 1/2016
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-015-1233-x

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