Skip to main content
Erschienen in: CardioVascular and Interventional Radiology 8/2017

29.03.2017 | Technical Note

Ultrasound-Guided Biopsies of Bone Lesions Without Cortical Disruption Using Fusion Imaging and Needle Tracking: Proof of Concept

verfasst von: Julien Garnon, Guillaume Koch, Georgia Tsoumakidou, Jean Caudrelier, Basavaraj Chari, Roberto Luigi Cazzato, Afshin Gangi

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 8/2017

Einloggen, um Zugang zu erhalten

Abstract

Objective

To assess the technical feasibility and safety of combined fusion imaging and needle tracking under ultrasound guidance to target bone lesions without cortical disruption.

Materials and Methods

Between January 2016 and March 2016, seven patients underwent US-guided biopsy of bone lesions without cortical disruption. Targeted bone lesions were measuring more than 1.5 cm with a thin cortex, a trans-osseous pathway not exceeding 2 cm and without any adjacent vulnerable structures. First three procedures were performed in the CT suite to aid the needle tracking where necessary (group 1), the remaining four procedures were performed in the US suite (group 2). In group 1, deviation from the real position of the bone trocar (estimated on CT) was compared to the virtual position (estimated on the fusion CT–US images). In both group, procedure data and histopathological results were collected, and compared to the suspected diagnosis and follow-up.

Results

Mean procedure duration was 44 min. Total number of synchronisation points for combined fusion imaging were 3.3 on average. In group 1, mean deviation between the virtual and real CT coordinates was 5.3 mm on average. All biopsies yielded adequate quality analysable bone sample. Histopathological analysis revealed malignancy in three cases, non-specific inflammation in two cases, and normal bone in two cases. The four benign results were confirmed as true negative results. There were no immediate or post-procedural complications.

Conclusion

The use of combined fusion imaging and needle tracking ultrasound guidance to target bone lesions without cortical disruption seems technically feasible, provided the patient and lesion selection is appropriate.
Literatur
1.
Zurück zum Zitat Vieillard MH, Boutry N, Chastanet P, Duquesnoy B, Cotten A, Cortet B. Contribution of percutaneous biopsy to the definite diagnosis in patients with suspected bone tumor. Joint Bone Spine. 2005;72(1):53–60.CrossRefPubMed Vieillard MH, Boutry N, Chastanet P, Duquesnoy B, Cotten A, Cortet B. Contribution of percutaneous biopsy to the definite diagnosis in patients with suspected bone tumor. Joint Bone Spine. 2005;72(1):53–60.CrossRefPubMed
2.
Zurück zum Zitat Monfardini L, Preda L, Aurilio G, Rizzo S, Bagnardi V, Renne G, Maccagnoni S, Vigna PD, Davide D, Bellomi M. CT-guided bone biopsy in cancer patients with suspected bone metastases: retrospective review of 308 procedures. Radiol Med. 2014;119(11):852–60. doi:10.1007/s11547-014-0401-4.CrossRefPubMed Monfardini L, Preda L, Aurilio G, Rizzo S, Bagnardi V, Renne G, Maccagnoni S, Vigna PD, Davide D, Bellomi M. CT-guided bone biopsy in cancer patients with suspected bone metastases: retrospective review of 308 procedures. Radiol Med. 2014;119(11):852–60. doi:10.​1007/​s11547-014-0401-4.CrossRefPubMed
3.
Zurück zum Zitat Tselikas L, Joskin J, Roquet F, Farouil G, Dreuil S, Hakimé A, Teriitehau C, Auperin A, de Baere T, Deschamps F. Percutaneous bone biopsies: comparison between flat-panel cone-beam CT and CT-scan guidance. Cardiovasc Intervent Radiol. 2015;38(1):167–76. doi:10.1007/s00270-014-0870-9.CrossRefPubMed Tselikas L, Joskin J, Roquet F, Farouil G, Dreuil S, Hakimé A, Teriitehau C, Auperin A, de Baere T, Deschamps F. Percutaneous bone biopsies: comparison between flat-panel cone-beam CT and CT-scan guidance. Cardiovasc Intervent Radiol. 2015;38(1):167–76. doi:10.​1007/​s00270-014-0870-9.CrossRefPubMed
5.
Zurück zum Zitat Saifuddin A, Mitchell R, Burnett SJ, Sandison A, Pringle JA. Ultrasound-guided needle biopsy of primary bone tumours. J Bone Joint Surg Br. 2000;82(1):50–4.CrossRefPubMed Saifuddin A, Mitchell R, Burnett SJ, Sandison A, Pringle JA. Ultrasound-guided needle biopsy of primary bone tumours. J Bone Joint Surg Br. 2000;82(1):50–4.CrossRefPubMed
7.
Zurück zum Zitat Song KD, Lee MW, Rhim H, Cha DI, Chong Y, Lim HK. Fusion imaging-guided radiofrequency ablation for hepatocellular carcinomas not visible on conventional ultrasound. AJR Am J Roentgenol. 2013;201(5):1141–7. doi:10.2214/AJR.13.10532.CrossRefPubMed Song KD, Lee MW, Rhim H, Cha DI, Chong Y, Lim HK. Fusion imaging-guided radiofrequency ablation for hepatocellular carcinomas not visible on conventional ultrasound. AJR Am J Roentgenol. 2013;201(5):1141–7. doi:10.​2214/​AJR.​13.​10532.CrossRefPubMed
8.
Zurück zum Zitat Makino Y, Imai Y, Ohama H, Igura T, Kogita S, Sawai Y, Fukuda K, Takamura M, Ohashi H, Murakami T. Ultrasonography fusion imaging system increases the chance of radiofrequency ablation for hepatocellular carcinoma with poor conspicuity on conventional ultrasonography. Oncology. 2013;84(Suppl 1):44–50. doi:10.1159/000345889.CrossRefPubMed Makino Y, Imai Y, Ohama H, Igura T, Kogita S, Sawai Y, Fukuda K, Takamura M, Ohashi H, Murakami T. Ultrasonography fusion imaging system increases the chance of radiofrequency ablation for hepatocellular carcinoma with poor conspicuity on conventional ultrasonography. Oncology. 2013;84(Suppl 1):44–50. doi:10.​1159/​000345889.CrossRefPubMed
9.
Zurück zum Zitat Hakime A, Deschamps F, De Carvalho EG, Barah A, Auperin A, De Baere T. Electromagnetic-tracked biopsy under ultrasound guidance: preliminary results. Cardiovasc Intervent Radiol. 2012;35(4):898–905. doi:10.1007/s00270-011-0278-8.CrossRefPubMed Hakime A, Deschamps F, De Carvalho EG, Barah A, Auperin A, De Baere T. Electromagnetic-tracked biopsy under ultrasound guidance: preliminary results. Cardiovasc Intervent Radiol. 2012;35(4):898–905. doi:10.​1007/​s00270-011-0278-8.CrossRefPubMed
10.
Zurück zum Zitat Patel IJ, Davidson JC, Nikolic B, Salazar GM, Schwartzberg MS, Walker TG, et al. Consensus guidelines for periprocedural management of coagulation status and hemostasis risk in percutaneous image-guided interventions. J Vasc Interv Radiol. 2012;23(6):727–36.CrossRefPubMed Patel IJ, Davidson JC, Nikolic B, Salazar GM, Schwartzberg MS, Walker TG, et al. Consensus guidelines for periprocedural management of coagulation status and hemostasis risk in percutaneous image-guided interventions. J Vasc Interv Radiol. 2012;23(6):727–36.CrossRefPubMed
11.
Zurück zum Zitat Khalil JG, Mott MP, Parsons TW 3rd, Banka TR, van Holsbeeck M. 2011 mid-America orthopaedic association Dallas B. Phemister physician in training award: Can musculoskeletal tumors be diagnosed with ultrasound fusion-guided biopsy? Clin Orthop Relat Res. 2012;470(8):2280–7. doi:10.1007/s11999-012-2405-5.CrossRefPubMedPubMedCentral Khalil JG, Mott MP, Parsons TW 3rd, Banka TR, van Holsbeeck M. 2011 mid-America orthopaedic association Dallas B. Phemister physician in training award: Can musculoskeletal tumors be diagnosed with ultrasound fusion-guided biopsy? Clin Orthop Relat Res. 2012;470(8):2280–7. doi:10.​1007/​s11999-012-2405-5.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Crocetti L, Lencioni R, Debeni S, See TC, Pina CD, Bartolozzi C. Targeting liver lesions for radiofrequency ablation: an experimental feasibility study using a CT–US fusion imaging system. Invest Radiol. 2008;43(1):33–9.CrossRefPubMed Crocetti L, Lencioni R, Debeni S, See TC, Pina CD, Bartolozzi C. Targeting liver lesions for radiofrequency ablation: an experimental feasibility study using a CT–US fusion imaging system. Invest Radiol. 2008;43(1):33–9.CrossRefPubMed
14.
Zurück zum Zitat Appelbaum L, Solbiati L, Sosna J, Nissenbaum Y, Greenbaum N, Goldberg SN. Evaluation of an electromagnetic image-fusion navigation system for biopsy of small lesions: assessment of accuracy in an in vivo swine model. Acad Radiol. 2013;20(2):209–17. doi:10.1016/j.acra.2012.09.020.CrossRefPubMed Appelbaum L, Solbiati L, Sosna J, Nissenbaum Y, Greenbaum N, Goldberg SN. Evaluation of an electromagnetic image-fusion navigation system for biopsy of small lesions: assessment of accuracy in an in vivo swine model. Acad Radiol. 2013;20(2):209–17. doi:10.​1016/​j.​acra.​2012.​09.​020.CrossRefPubMed
15.
Zurück zum Zitat März K, Franz AM, Seitel A, Winterstein A, Hafezi M, Saffari A, Bendl R, Stieltjes B, Meinzer HP, Mehrabi A, Maier-Hein L. Interventional real-time ultrasound imaging with an integrated electromagnetic field generator. Comput Assist Radiol Surg. 2014;9(5):759–68. doi:10.1007/s11548-014-0990-3.CrossRef März K, Franz AM, Seitel A, Winterstein A, Hafezi M, Saffari A, Bendl R, Stieltjes B, Meinzer HP, Mehrabi A, Maier-Hein L. Interventional real-time ultrasound imaging with an integrated electromagnetic field generator. Comput Assist Radiol Surg. 2014;9(5):759–68. doi:10.​1007/​s11548-014-0990-3.CrossRef
Metadaten
Titel
Ultrasound-Guided Biopsies of Bone Lesions Without Cortical Disruption Using Fusion Imaging and Needle Tracking: Proof of Concept
verfasst von
Julien Garnon
Guillaume Koch
Georgia Tsoumakidou
Jean Caudrelier
Basavaraj Chari
Roberto Luigi Cazzato
Afshin Gangi
Publikationsdatum
29.03.2017
Verlag
Springer US
Erschienen in
CardioVascular and Interventional Radiology / Ausgabe 8/2017
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-017-1638-9

Weitere Artikel der Ausgabe 8/2017

CardioVascular and Interventional Radiology 8/2017 Zur Ausgabe

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Klinik aktuell Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.