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Erschienen in: Rheumatology International 1/2006

01.11.2006 | Original Article

Balneotherapy and tap water therapy in the treatment of knee osteoarthritis

verfasst von: Merih Yurtkuran, Mustafa Yurtkuran, Alev Alp, Aşkın Nasırcılar, Ümit Bingöl, Lale Altan, Gülnazik Sarpdere

Erschienen in: Rheumatology International | Ausgabe 1/2006

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Abstract

To investigate if spa water is superior to tap water (TW) in relieving the symptoms of pain, joint motion, life quality in knee osteoarthritis (KOA) patients. In this randomized placebo-controlled trial, 52 patients with KOA were followed in two groups. In group I (n = 27), patients were treated in the pool full of spa water at 37°C for 20 min a day, 5 days a week, for a period of 2 weeks. In group II (n = 25), the same protocol was used but spa water was replaced by TW heated to 37°C. Patients in both groups were given a home-based standardized exercise program. Evaluation parameters were pain (pVAS), tenderness score (TS), 50-ft walking duration, quadriceps muscle strength (QMS), active flexion degree (AFD), WOMAC OA index, and Nottingham Health Profile (NHP). The first evaluation was done after the informed consent was obtained. Second and third evaluations were done at the 2nd and 12th week. PVAS, 50-ft walking duration, AFD, TS, WOMAC, and NHP variables improved in group I. Same variables except QMS improved also in group II. Comparison of the groups just after treatment showed that only pVAS (P = 0.015), NHP pain score (P = 0.020), and TS (P = 0.002) differed significantly in favor of group I at the 2nd or 12th week. Both of the thermal treatment modalities were found to be effective in the management of the clinical symptoms and quality of life in KOA patients. However, pain and tenderness improved statistically better with balneotherapy. There were no significant differences between the groups for the other variables.
Literatur
1.
Zurück zum Zitat Pritzker K (2003) Pathology of osteoarthritis. In: Brandt K, Doherty M, Lohmander LS (eds) Osteoarthritis, 2nd edn. Oxford University Press, Oxford, pp 49–58 Pritzker K (2003) Pathology of osteoarthritis. In: Brandt K, Doherty M, Lohmander LS (eds) Osteoarthritis, 2nd edn. Oxford University Press, Oxford, pp 49–58
2.
Zurück zum Zitat Jordan KM, Arden NK, Doherty M et al (2003) EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis 62:1145–1155PubMedCrossRef Jordan KM, Arden NK, Doherty M et al (2003) EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis 62:1145–1155PubMedCrossRef
3.
Zurück zum Zitat Dieppe P, Lohmander S (2005) Pathogenesis and management of pain in osteoarthritis. Lancet 365:965–973PubMedCrossRef Dieppe P, Lohmander S (2005) Pathogenesis and management of pain in osteoarthritis. Lancet 365:965–973PubMedCrossRef
4.
Zurück zum Zitat Ehrlich GE (2003) The rise of osteoarthritis. Bull WHO 81:630PubMed Ehrlich GE (2003) The rise of osteoarthritis. Bull WHO 81:630PubMed
5.
Zurück zum Zitat Woof AD, Akesson K (2001) Understanding the burden of musculoskeletal conditions. The burden is huge and not reflected in national health priorities. BMJ 322:1079–1080CrossRef Woof AD, Akesson K (2001) Understanding the burden of musculoskeletal conditions. The burden is huge and not reflected in national health priorities. BMJ 322:1079–1080CrossRef
6.
Zurück zum Zitat Dieppe P, Basler HD, Chard J, Croft P, Dixon J, Hurley M (1999) Knee replacement surgery for osteoarthritis: effectiveness, practice variations, indications and possible determinants of utilisation. Rheumatology (Oxford) 38:73–77CrossRef Dieppe P, Basler HD, Chard J, Croft P, Dixon J, Hurley M (1999) Knee replacement surgery for osteoarthritis: effectiveness, practice variations, indications and possible determinants of utilisation. Rheumatology (Oxford) 38:73–77CrossRef
7.
Zurück zum Zitat American College of Rheumatology Subcommittee on Osteoarthritis Guidelines (2000) Recommendations for the medical management of osteoarthritis of the hip and knee. Arthritis Rheum 43:1905–1915 American College of Rheumatology Subcommittee on Osteoarthritis Guidelines (2000) Recommendations for the medical management of osteoarthritis of the hip and knee. Arthritis Rheum 43:1905–1915
8.
Zurück zum Zitat Pendleton A, Arden N, Dougados M et al (2000) EULAR recommendations for the management of knee osteoarthritis: report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis 59:936–944PubMedCrossRef Pendleton A, Arden N, Dougados M et al (2000) EULAR recommendations for the management of knee osteoarthritis: report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis 59:936–944PubMedCrossRef
9.
Zurück zum Zitat Yurtkuran M, Kocagil T (1999) TENS, electroacupuncture and ice massage: comparison of treatment for osteoarthritis of the knee. Am J Acupunct 27:133–140PubMed Yurtkuran M, Kocagil T (1999) TENS, electroacupuncture and ice massage: comparison of treatment for osteoarthritis of the knee. Am J Acupunct 27:133–140PubMed
10.
Zurück zum Zitat Ay A, Yurtkuran M (2005) Influence of aquatic and weight-bearing exercises on quantitative ultrasound variables in postmenopausal women. Am J Phys Med Rehabil 84(1):52–61PubMedCrossRef Ay A, Yurtkuran M (2005) Influence of aquatic and weight-bearing exercises on quantitative ultrasound variables in postmenopausal women. Am J Phys Med Rehabil 84(1):52–61PubMedCrossRef
11.
Zurück zum Zitat Sukenik S, Flusser D, Abu-Shakra (1999) The role of spa therapy in various rheumatic disease. Rheum Dis North Am 25:883–897CrossRef Sukenik S, Flusser D, Abu-Shakra (1999) The role of spa therapy in various rheumatic disease. Rheum Dis North Am 25:883–897CrossRef
12.
Zurück zum Zitat Yurtkuran M, Kahraman Z, Sivriglu K, Afşin Y, Doğan M (1997) Balneotherapy in low back pain. Eur J Phys Med Rehabil 7:120–123 Yurtkuran M, Kahraman Z, Sivriglu K, Afşin Y, Doğan M (1997) Balneotherapy in low back pain. Eur J Phys Med Rehabil 7:120–123
13.
Zurück zum Zitat Yurtkuran M, Yurtkuran MA, Dilek K, Güllülü M, Karakoç Y, Özbek L et al (1999) A randomized, controlled study of balneotherapy in patients with rheumatoid arthritis. Phys Rehabil Kur Med 9:92–96 Yurtkuran M, Yurtkuran MA, Dilek K, Güllülü M, Karakoç Y, Özbek L et al (1999) A randomized, controlled study of balneotherapy in patients with rheumatoid arthritis. Phys Rehabil Kur Med 9:92–96
14.
Zurück zum Zitat Sukenik S, Baradin R, Codish S, Neumann L, Flusser D, Abu-Shakra M et al (2001) Balneotherapy at the Dead Sea area for patients with psoriatic arthritis and concomitant fibromyalgia. Isr Med Assoc J 3:147–150PubMed Sukenik S, Baradin R, Codish S, Neumann L, Flusser D, Abu-Shakra M et al (2001) Balneotherapy at the Dead Sea area for patients with psoriatic arthritis and concomitant fibromyalgia. Isr Med Assoc J 3:147–150PubMed
15.
Zurück zum Zitat Neumann L, Sukenik S, Bolotin M, Abu-Shakra M, Amir M, Flusser D (2001) The effect of balneotherapy at the Dead Sea on the quality of life of patients with fibromyalgia syndrome. Clin Rheumatol 20:15–19PubMedCrossRef Neumann L, Sukenik S, Bolotin M, Abu-Shakra M, Amir M, Flusser D (2001) The effect of balneotherapy at the Dead Sea on the quality of life of patients with fibromyalgia syndrome. Clin Rheumatol 20:15–19PubMedCrossRef
16.
Zurück zum Zitat Altan L, Bingöl U, Aykaç M, Koc Z, Yurtkuran M (2004) Investigation of the effects of pool-based exercise on fibromyalgia syndrome. Rheumatol Int 24(5):272–277PubMedCrossRef Altan L, Bingöl U, Aykaç M, Koc Z, Yurtkuran M (2004) Investigation of the effects of pool-based exercise on fibromyalgia syndrome. Rheumatol Int 24(5):272–277PubMedCrossRef
17.
Zurück zum Zitat Verhagen AP, Bierma-Zeinstra SMA, Cardoso JR, de Bie RA, Boers M, de Vet HCW (2005) Balneotherapy for rheumatoid arthritis. Cochrane Database Syst Rev 1 Verhagen AP, Bierma-Zeinstra SMA, Cardoso JR, de Bie RA, Boers M, de Vet HCW (2005) Balneotherapy for rheumatoid arthritis. Cochrane Database Syst Rev 1
18.
Zurück zum Zitat Elkayam O, Wigler I, Tishler M, Rosenblum I, Caspi D, Segal R (1991) Effect of spa therapy in Tiberias on patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 18:1799–1803PubMed Elkayam O, Wigler I, Tishler M, Rosenblum I, Caspi D, Segal R (1991) Effect of spa therapy in Tiberias on patients with rheumatoid arthritis and osteoarthritis. J Rheumatol 18:1799–1803PubMed
19.
Zurück zum Zitat Franke A, Reiner L, Pratzel HG, Franke T, Resch KL (2000) Long term efficacy of radon spa therapy in rheumatoid arthritis; a randomized sham-controlled study and follow-up. Rheumatology 39:894–902PubMedCrossRef Franke A, Reiner L, Pratzel HG, Franke T, Resch KL (2000) Long term efficacy of radon spa therapy in rheumatoid arthritis; a randomized sham-controlled study and follow-up. Rheumatology 39:894–902PubMedCrossRef
20.
Zurück zum Zitat Lehmann JE (ed) (1990) Krusen’s handbook of physical Medicine and rehabilitation. W.B. Saunders Company, Philadelphia Lehmann JE (ed) (1990) Krusen’s handbook of physical Medicine and rehabilitation. W.B. Saunders Company, Philadelphia
21.
Zurück zum Zitat Nguyen M, Revel M, Dougados M (1997) Prolonged effects of 3 week therapy in a spa resort on lumbar spine, knee and hip osteoarthritis: follow-up after 6 months. A randomized controlled trial. Br J Rheumatol 36:77–81PubMedCrossRef Nguyen M, Revel M, Dougados M (1997) Prolonged effects of 3 week therapy in a spa resort on lumbar spine, knee and hip osteoarthritis: follow-up after 6 months. A randomized controlled trial. Br J Rheumatol 36:77–81PubMedCrossRef
22.
Zurück zum Zitat Guillemin F, Virion JM, Escudier P, De Talance N, Weryha G (2001) Effect on osteoarthritis of spa therapy at Bourbonne-les Bains. Joint Bone Spine 68:499–503PubMedCrossRef Guillemin F, Virion JM, Escudier P, De Talance N, Weryha G (2001) Effect on osteoarthritis of spa therapy at Bourbonne-les Bains. Joint Bone Spine 68:499–503PubMedCrossRef
23.
Zurück zum Zitat Verhagen AP, de Vet HC, de Bie RA, Kessels AG, Boers M, Knipschild PG (2001) Balneotherapy for rheumatoid arthritis and osteoarthritis (Cochrane review). In: The Cochrane Library, Issue 1. Oxford: Update Software Verhagen AP, de Vet HC, de Bie RA, Kessels AG, Boers M, Knipschild PG (2001) Balneotherapy for rheumatoid arthritis and osteoarthritis (Cochrane review). In: The Cochrane Library, Issue 1. Oxford: Update Software
24.
Zurück zum Zitat Altman RD, Blach DA, Bole GG, Brandt KD, Cooke DV, Greenwald RA (1999) Development of criteria for osteoarthritis. J Rheumatol 26:1959–1963 Altman RD, Blach DA, Bole GG, Brandt KD, Cooke DV, Greenwald RA (1999) Development of criteria for osteoarthritis. J Rheumatol 26:1959–1963
25.
Zurück zum Zitat Kellgren JS, Lawrence JS (1957) Radiological assessment of osteoarthrosis. Ann Rheum Dis 16:494–502PubMed Kellgren JS, Lawrence JS (1957) Radiological assessment of osteoarthrosis. Ann Rheum Dis 16:494–502PubMed
26.
Zurück zum Zitat Huskisson EC (1983) Visual analogue scale. In: Melzack R (ed) Pain measurement and assessment. Raven Press, New York, pp 33–37 Huskisson EC (1983) Visual analogue scale. In: Melzack R (ed) Pain measurement and assessment. Raven Press, New York, pp 33–37
27.
Zurück zum Zitat Fisher AA (1986) Pressure threshold meter: its use for quantification of tender spots. Arch Phys Med Rehabil 67:836–838 Fisher AA (1986) Pressure threshold meter: its use for quantification of tender spots. Arch Phys Med Rehabil 67:836–838
28.
Zurück zum Zitat Yurtkuran M, Çeliktaş M (1996) A randomised controlled trial of balneotherapy in the treatment of patients with primary fibromyalgia syndrome. Phys Rehabil Kur Med 6:109–112 Yurtkuran M, Çeliktaş M (1996) A randomised controlled trial of balneotherapy in the treatment of patients with primary fibromyalgia syndrome. Phys Rehabil Kur Med 6:109–112
29.
Zurück zum Zitat Bellamy N, Buchanan WW, Goldsmith CH, Camphell J, Stiff LW (1986) Validation study of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Arthritis Rheum 29:1039–1049 Bellamy N, Buchanan WW, Goldsmith CH, Camphell J, Stiff LW (1986) Validation study of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Arthritis Rheum 29:1039–1049
30.
Zurück zum Zitat Bellamy N, Buchanan WW, Goldsmith CH, Camphell J, Stiff LW (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip and knee. J Rheumatol 15:1833–1840PubMed Bellamy N, Buchanan WW, Goldsmith CH, Camphell J, Stiff LW (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip and knee. J Rheumatol 15:1833–1840PubMed
31.
Zurück zum Zitat Bores M, Brooks P, Strand VC et al (1998) The OMERACT filter for outcome measures in rheumatology. J Rheumatol 25:198–199 Bores M, Brooks P, Strand VC et al (1998) The OMERACT filter for outcome measures in rheumatology. J Rheumatol 25:198–199
32.
Zurück zum Zitat Martini CJM, Waugh IM (1978) A method for self. Assessment of disability before and after hip replacement operation. BMJ 2:258–259 Martini CJM, Waugh IM (1978) A method for self. Assessment of disability before and after hip replacement operation. BMJ 2:258–259
33.
Zurück zum Zitat Kucukdeveci AA, Mckenna SP, Kutlay S, Gursel Y, Whalley D, Arasıl T (2000) The development and psychometric assessment of the Turkish version of the Nottingham Health Profile. Int J Rehabil Res 23:31–38PubMedCrossRef Kucukdeveci AA, Mckenna SP, Kutlay S, Gursel Y, Whalley D, Arasıl T (2000) The development and psychometric assessment of the Turkish version of the Nottingham Health Profile. Int J Rehabil Res 23:31–38PubMedCrossRef
34.
Zurück zum Zitat Becker BE (1994) The biologic aspects of hydrotherapy. J Back Musculoskeletal Rehabil 4:255–264 Becker BE (1994) The biologic aspects of hydrotherapy. J Back Musculoskeletal Rehabil 4:255–264
35.
Zurück zum Zitat Golland A (1981) Basic hydrotherapy. Physiotherapy 67:258–262PubMed Golland A (1981) Basic hydrotherapy. Physiotherapy 67:258–262PubMed
36.
Zurück zum Zitat Sukenik S (1994) Spa treatment for arthritis at the Dead Sea area. Editorial. Isr J Med Sci 30:919–921PubMed Sukenik S (1994) Spa treatment for arthritis at the Dead Sea area. Editorial. Isr J Med Sci 30:919–921PubMed
37.
Zurück zum Zitat O’hare JP, Heywood A, Summerhayes C et al (1985) Observations on the effect of immersion in bath spa water. BMJ 291:1747–1751PubMedCrossRef O’hare JP, Heywood A, Summerhayes C et al (1985) Observations on the effect of immersion in bath spa water. BMJ 291:1747–1751PubMedCrossRef
38.
Zurück zum Zitat Lange U, Muller-Ladner U, Schmidt KL (2005) Balneotherapy in rheumatic diseases—an overview of novel and known aspects. Rheumatol Int 12:1–3 Lange U, Muller-Ladner U, Schmidt KL (2005) Balneotherapy in rheumatic diseases—an overview of novel and known aspects. Rheumatol Int 12:1–3
39.
Zurück zum Zitat Forestier R (2001) Magnitude and duration of the effects of two spa therapy courses on knee and hip osteoarthritis: an open prospective study in 51 consecutive patients. With fibromyalgia syndome. Clin Rheumatol 20:15–19CrossRef Forestier R (2001) Magnitude and duration of the effects of two spa therapy courses on knee and hip osteoarthritis: an open prospective study in 51 consecutive patients. With fibromyalgia syndome. Clin Rheumatol 20:15–19CrossRef
40.
Zurück zum Zitat Lehmann J, Lateur B (1994) Ultrasound, shortwave, microwave, laser, superficial heat and cold in the treatment of pain. In: Wall P, Melzack R (eds) Textbook of pain. Churchill Livingstone, London, pp 1237–1246 Lehmann J, Lateur B (1994) Ultrasound, shortwave, microwave, laser, superficial heat and cold in the treatment of pain. In: Wall P, Melzack R (eds) Textbook of pain. Churchill Livingstone, London, pp 1237–1246
41.
Zurück zum Zitat Yurtkuran M, Ulus H, İrdesel J (1993) The effect of balneotherapy on plasma endorphine level in patients with osteoarthritis. Phys Rehabil Kur Med 3:130–138CrossRef Yurtkuran M, Ulus H, İrdesel J (1993) The effect of balneotherapy on plasma endorphine level in patients with osteoarthritis. Phys Rehabil Kur Med 3:130–138CrossRef
42.
Zurück zum Zitat Davis B, Harrison R (1988) Treatment of specific conditions. In: Davis B, Harrison R (eds) Hydrotherapy in practise. Churchill Livingstone, Singapore, pp 137–170 Davis B, Harrison R (1988) Treatment of specific conditions. In: Davis B, Harrison R (eds) Hydrotherapy in practise. Churchill Livingstone, Singapore, pp 137–170
43.
Zurück zum Zitat Kondrad K, Tatrai T, Hunka A, Vereckei E, Korondi I (1992) Controlled trial of balneotherapy in treatment of low back pain. Ann Rheum Dis 51:820–822CrossRef Kondrad K, Tatrai T, Hunka A, Vereckei E, Korondi I (1992) Controlled trial of balneotherapy in treatment of low back pain. Ann Rheum Dis 51:820–822CrossRef
44.
Zurück zum Zitat Böhmer H, Resch KL, Gutenbrunner C (1999) Sulfat-Heilwässer-eine zeitgemäße medikamentöse Alternative? Phys Rehabil Kur Med 9:1–5 Böhmer H, Resch KL, Gutenbrunner C (1999) Sulfat-Heilwässer-eine zeitgemäße medikamentöse Alternative? Phys Rehabil Kur Med 9:1–5
45.
Zurück zum Zitat Karagülle MZ, Tütüncü ZN, Aslan O et al (1996) Effects of therma sulfur bath cure on adjuvant arthritic rats. Phys Rehabil Kur Med 6:53–57 Karagülle MZ, Tütüncü ZN, Aslan O et al (1996) Effects of therma sulfur bath cure on adjuvant arthritic rats. Phys Rehabil Kur Med 6:53–57
46.
Zurück zum Zitat Kovacs I, Bender T (2002) The therapeutic effects of Cserkeszölö thermal water in osteoarthritis of the knee: a double blind, controlled, follow up study. Rheumatol Int 21:258–261CrossRef Kovacs I, Bender T (2002) The therapeutic effects of Cserkeszölö thermal water in osteoarthritis of the knee: a double blind, controlled, follow up study. Rheumatol Int 21:258–261CrossRef
47.
Zurück zum Zitat Sukenic S, Flusser D, Codish S, Ahu-Shakra M (1999) Balneotherapy at the dead sea area for knee osteoarthritis. Isr Med Assoc J 1:83–85 Sukenic S, Flusser D, Codish S, Ahu-Shakra M (1999) Balneotherapy at the dead sea area for knee osteoarthritis. Isr Med Assoc J 1:83–85
48.
Zurück zum Zitat Wigler I, Elkayam O, Paran D, Yaron M (1995) Spa therapy for gonarthrosis: a prospective study. Rheumatol Int 15:65–68PubMedCrossRef Wigler I, Elkayam O, Paran D, Yaron M (1995) Spa therapy for gonarthrosis: a prospective study. Rheumatol Int 15:65–68PubMedCrossRef
49.
Zurück zum Zitat Nguyen M, Revel M, Dougados M (1997) Prolonged effects of 3 week therapy in a Spa resort on lumbar spine, knee and hip osteoarthritis: follow-up after 6 months. A randomized controlled trial. Br J Rheumatol 36:77–81PubMedCrossRef Nguyen M, Revel M, Dougados M (1997) Prolonged effects of 3 week therapy in a Spa resort on lumbar spine, knee and hip osteoarthritis: follow-up after 6 months. A randomized controlled trial. Br J Rheumatol 36:77–81PubMedCrossRef
50.
Zurück zum Zitat Goldsmith CH, Boers M, Bombardier C, Tugwell P (1993) Criteria for clinically important changes in outcomes: development, scoring and evaluation of rheumatoid arthritis patient and trial profiles. OMERACT committee. J Rheumatol 20:561–565PubMed Goldsmith CH, Boers M, Bombardier C, Tugwell P (1993) Criteria for clinically important changes in outcomes: development, scoring and evaluation of rheumatoid arthritis patient and trial profiles. OMERACT committee. J Rheumatol 20:561–565PubMed
51.
Zurück zum Zitat Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P (1997) Recommendations for a core set outcome measure for future phase III clinical trials in knee, hip and hand OA. Consensus development at OMERACT III. J Rheumatol 24:799–802PubMed Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P (1997) Recommendations for a core set outcome measure for future phase III clinical trials in knee, hip and hand OA. Consensus development at OMERACT III. J Rheumatol 24:799–802PubMed
52.
Zurück zum Zitat Angst F, Aeschlimann A, Steiner W, Stucki G (2001) Responsiveness of the WOMAC osteoarthritis index as compared with the SF-36 in patients with osteoarthritis of the legs undergoing a comprehensive rehabilitation intervention. Ann Rheum Dis 60:834–840PubMed Angst F, Aeschlimann A, Steiner W, Stucki G (2001) Responsiveness of the WOMAC osteoarthritis index as compared with the SF-36 in patients with osteoarthritis of the legs undergoing a comprehensive rehabilitation intervention. Ann Rheum Dis 60:834–840PubMed
53.
Zurück zum Zitat Salaffi F, Stancati A, Silvestri CA, Ciapetti A, Grassi W (2004) Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale. Eur J Pain 8(4):283–291PubMedCrossRef Salaffi F, Stancati A, Silvestri CA, Ciapetti A, Grassi W (2004) Minimal clinically important changes in chronic musculoskeletal pain intensity measured on a numerical rating scale. Eur J Pain 8(4):283–291PubMedCrossRef
54.
Zurück zum Zitat Wann-Hansson C, Hallberg I, Risberg B et al (2004) A comparison of the Nottingham Health Profile and Short Form 36 Health Survey in patients with chronic lower limb ischaemia in a longitudinal perspective. Health Qual Life Outcomes 2(1):9PubMedCrossRef Wann-Hansson C, Hallberg I, Risberg B et al (2004) A comparison of the Nottingham Health Profile and Short Form 36 Health Survey in patients with chronic lower limb ischaemia in a longitudinal perspective. Health Qual Life Outcomes 2(1):9PubMedCrossRef
55.
Zurück zum Zitat Szücs L, Ratko L, Lesko T, Szoor I, Genti G et al (1989) Double blind trial on the effectiveness of the Puspokladany thermal water on arthrosis of the knee joint. Roy Soc Health J 109:7–9 Szücs L, Ratko L, Lesko T, Szoor I, Genti G et al (1989) Double blind trial on the effectiveness of the Puspokladany thermal water on arthrosis of the knee joint. Roy Soc Health J 109:7–9
Metadaten
Titel
Balneotherapy and tap water therapy in the treatment of knee osteoarthritis
verfasst von
Merih Yurtkuran
Mustafa Yurtkuran
Alev Alp
Aşkın Nasırcılar
Ümit Bingöl
Lale Altan
Gülnazik Sarpdere
Publikationsdatum
01.11.2006
Verlag
Springer-Verlag
Erschienen in
Rheumatology International / Ausgabe 1/2006
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-006-0158-8

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