Skip to main content
Erschienen in: European Radiology 11/2018

14.05.2018 | Ultrasound

Ultrasonography in diagnosing clinically occult groin hernia: systematic review and meta-analysis

verfasst von: Robert M. Kwee, Thomas C. Kwee

Erschienen in: European Radiology | Ausgabe 11/2018

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To provide an updated systematic review on the performance of ultrasonography (US) in diagnosing clinically occult groin hernia.

Methods

A systematic search was performed in MEDLINE and Embase. Methodological quality of included studies was assessed. Accuracy data of US in detecting clinically occult groin hernia were extracted. Positive predictive value (PPV) was pooled with a random effects model. For studies investigating the performance of US in hernia type classification (inguinal vs femoral), correctly classified proportion was assessed.

Results

Sixteen studies were included. In the two studies without verification bias, sensitivities were 29.4% [95% confidence interval (CI), 15.1-47.5%] and 90.9% (95% CI, 70.8-98.9%); specificities were 90.0% (95% CI, 80.5-95.9%) and 90.6% (95% CI, 83.0-95.6%). Verification bias or a variation of it (i.e. study limited to only subjects with definitive proof of disease status) was present in all other studies. Sensitivity, specificity, and negative predictive value (NPV) were not pooled. PPV ranged from 58.8 to 100%. Pooled PPV, based on data from ten studies with low risk of bias and no applicability concerns with respect to patient selection, was 85.6% (95% CI, 76.5-92.7%). Proportion of correctly classified hernias, based on data from four studies, ranged between 94.4% and 99.1%.

Conclusions

Sensitivity, specificity and NPV of US in detecting clinically occult groin hernia cannot reliably be determined based on current evidence. Further studies are necessary. Accuracy may strongly depend on the examiner's skills. PPV is high. Inguinal and femoral hernias can reliably be differentiated by US.

Key Points

• Sensitivity, specificity and NPV of ultrasound in detecting clinically occult groin hernia cannot reliably be determined based on current evidence.
• Accuracy may strongly depend on the examiner's skills.
• PPV of US in detection of clinically occult groin hernia is high [pooled PPV of 85.6% (95% confidence interval, 76.5-92.7%)].
• US has very high performance in correctly differentiating between clinically occult inguinal and femoral hernia (correctness of 94.4- 99.1%).
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Kingsnorth A, LeBlanc K (2003) Hernias: inguinal and incisional. Lancet 362:1561–1571CrossRef Kingsnorth A, LeBlanc K (2003) Hernias: inguinal and incisional. Lancet 362:1561–1571CrossRef
2.
Zurück zum Zitat Primatesta P, Goldacre MJ (1996) Inguinal hernia repair: incidence of elective and emergency surgery, readmission and mortality. Int J Epidemiol 25:835–839CrossRef Primatesta P, Goldacre MJ (1996) Inguinal hernia repair: incidence of elective and emergency surgery, readmission and mortality. Int J Epidemiol 25:835–839CrossRef
3.
Zurück zum Zitat HerniaSurge Group (2018) International guidelines for groin hernia management. Hernia 22:1–165CrossRef HerniaSurge Group (2018) International guidelines for groin hernia management. Hernia 22:1–165CrossRef
4.
5.
Zurück zum Zitat Niebuhr H, König A, Pawlak M, Sailer M, Köckerling F, Reinpold W (2017) Groin hernia diagnostics: dynamic inguinal ultrasound (DIUS). Langenbeck's Arch Surg 402:1039–1045CrossRef Niebuhr H, König A, Pawlak M, Sailer M, Köckerling F, Reinpold W (2017) Groin hernia diagnostics: dynamic inguinal ultrasound (DIUS). Langenbeck's Arch Surg 402:1039–1045CrossRef
6.
Zurück zum Zitat LeBlanc KE, LeBlanc LL, LeBlanc KA (2013) Inguinal hernias: diagnosis and management. Am Fam Physician 87:844–848PubMed LeBlanc KE, LeBlanc LL, LeBlanc KA (2013) Inguinal hernias: diagnosis and management. Am Fam Physician 87:844–848PubMed
7.
Zurück zum Zitat Robinson A, Light D, Kasim A, Nice C (2013) A systematic review and meta-analysis of the role of radiology in the diagnosis of occult inguinal hernia. Surg Endosc 27:11–18CrossRef Robinson A, Light D, Kasim A, Nice C (2013) A systematic review and meta-analysis of the role of radiology in the diagnosis of occult inguinal hernia. Surg Endosc 27:11–18CrossRef
8.
Zurück zum Zitat Lilly MC, Arregui ME (2002) Ultrasound of the inguinal floor for evaluation of hernias. Surg Endosc 16:659–662CrossRef Lilly MC, Arregui ME (2002) Ultrasound of the inguinal floor for evaluation of hernias. Surg Endosc 16:659–662CrossRef
9.
Zurück zum Zitat Light D, Ratnasingham K, Banerjee A, Cadwallader R, Uzzaman MM, Gopinath B (2011) The role of ultrasound scan in the diagnosis of occult inguinal hernias. Int J Surg 9:169–172CrossRef Light D, Ratnasingham K, Banerjee A, Cadwallader R, Uzzaman MM, Gopinath B (2011) The role of ultrasound scan in the diagnosis of occult inguinal hernias. Int J Surg 9:169–172CrossRef
10.
Zurück zum Zitat Depasquale R, Landes C, Doyle G (2009) Audit of ultrasound and decision to operate in groin pain of unknown aetiology with ultrasound technique explained. Clin Radiol 64:608–614CrossRef Depasquale R, Landes C, Doyle G (2009) Audit of ultrasound and decision to operate in groin pain of unknown aetiology with ultrasound technique explained. Clin Radiol 64:608–614CrossRef
11.
Zurück zum Zitat McGrath TA, McInnes MD, Korevaar DA, Bossuyt PM (2016) Meta-analyses of diagnostic accuracy in imaging journals: analysis of pooling techniques and their effect on summary estimates of diagnostic accuracy. Radiology 281:78–85CrossRef McGrath TA, McInnes MD, Korevaar DA, Bossuyt PM (2016) Meta-analyses of diagnostic accuracy in imaging journals: analysis of pooling techniques and their effect on summary estimates of diagnostic accuracy. Radiology 281:78–85CrossRef
12.
13.
Zurück zum Zitat McInnes MD, Bossuyt PM (2015) Pitfalls of systematic reviews and meta-analyses in imaging research. Radiology 277:13–21CrossRef McInnes MD, Bossuyt PM (2015) Pitfalls of systematic reviews and meta-analyses in imaging research. Radiology 277:13–21CrossRef
14.
Zurück zum Zitat Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JA, Bossuyt PM, QUADAS-2 Group (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRef Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JA, Bossuyt PM, QUADAS-2 Group (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155:529–536CrossRef
15.
Zurück zum Zitat Alam A, Nice C, Uberoi R (2005) The accuracy of ultrasound in the diagnosis of clinically occult groin hernias in adults. Eur Radiol 15:2457–2561CrossRef Alam A, Nice C, Uberoi R (2005) The accuracy of ultrasound in the diagnosis of clinically occult groin hernias in adults. Eur Radiol 15:2457–2561CrossRef
16.
Zurück zum Zitat Freeman MF, Tukey JW (1950) Transformations related to the angular and the square root. Ann Math Stat 21:607–611CrossRef Freeman MF, Tukey JW (1950) Transformations related to the angular and the square root. Ann Math Stat 21:607–611CrossRef
17.
Zurück zum Zitat DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177–188CrossRef DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177–188CrossRef
18.
Zurück zum Zitat Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560CrossRef Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560CrossRef
19.
Zurück zum Zitat Deitch EA, Soncrant MC (1981) Ultrasonic diagnosis of surgical disease of the inguinal-femoral region. Surg Gynecol Obstet 152:319–322PubMed Deitch EA, Soncrant MC (1981) Ultrasonic diagnosis of surgical disease of the inguinal-femoral region. Surg Gynecol Obstet 152:319–322PubMed
20.
Zurück zum Zitat Kervancioglu R, Bayram MM, Ertaskin I, Ozkur A (2000) Ultrasonographic evaluation of bilateral groins in children with unilateral inguinal hernia. Acta Radiol 41:653–657CrossRef Kervancioglu R, Bayram MM, Ertaskin I, Ozkur A (2000) Ultrasonographic evaluation of bilateral groins in children with unilateral inguinal hernia. Acta Radiol 41:653–657CrossRef
21.
Zurück zum Zitat Chen KC, Chu CC, Chou TY, Wu CJ (1998) Ultrasonography for inguinal hernias in boys. J Pediatr Surg 33:1784–1787CrossRef Chen KC, Chu CC, Chou TY, Wu CJ (1998) Ultrasonography for inguinal hernias in boys. J Pediatr Surg 33:1784–1787CrossRef
22.
Zurück zum Zitat Kraft BM, Kolb H, Kuckuk B et al (2003) Diagnosis and classification of inguinal hernias. Surg Endosc 17:2021–2024CrossRef Kraft BM, Kolb H, Kuckuk B et al (2003) Diagnosis and classification of inguinal hernias. Surg Endosc 17:2021–2024CrossRef
23.
Zurück zum Zitat Dattola P, Alberti A, Dattola A, Giannetto G, Basile G, Basile M (2002) Inguino-crural hernias: preoperative diagnosis and post-operative follow-up by high-resolution ultrasonography. A personal experience. Ann Ital Chir 73:65–68PubMed Dattola P, Alberti A, Dattola A, Giannetto G, Basile G, Basile M (2002) Inguino-crural hernias: preoperative diagnosis and post-operative follow-up by high-resolution ultrasonography. A personal experience. Ann Ital Chir 73:65–68PubMed
24.
Zurück zum Zitat Korenkov M, Paul A, Troidl H (1999) Color duplex sonography: diagnostic tool in the differentiation of inguinal hernias. J Ultrasound Med 18:565–568CrossRef Korenkov M, Paul A, Troidl H (1999) Color duplex sonography: diagnostic tool in the differentiation of inguinal hernias. J Ultrasound Med 18:565–568CrossRef
25.
Zurück zum Zitat Djuric-Stefanovic A, Saranovic D, Ivanovic A et al (2008) The accuracy of ultrasonography in classification of groin hernias according to the criteria of the unified classification system. Hernia 12:395–400CrossRef Djuric-Stefanovic A, Saranovic D, Ivanovic A et al (2008) The accuracy of ultrasonography in classification of groin hernias according to the criteria of the unified classification system. Hernia 12:395–400CrossRef
26.
Zurück zum Zitat Yeh HC, Lehr-Janus C, Cohen BA, Rabinowitz JG (1984) Ultrasonography and CT of abdominal and inguinal hernias. J Clin Ultrasound 12:479–486CrossRef Yeh HC, Lehr-Janus C, Cohen BA, Rabinowitz JG (1984) Ultrasonography and CT of abdominal and inguinal hernias. J Clin Ultrasound 12:479–486CrossRef
27.
Zurück zum Zitat Malouf PA, Descallar J, Berney CR (2018) Bilateral totally extraperitoneal (TEP) repair of the ultrasound-diagnosed asymptomatic contralateral inguinal hernia. Surg Endosc 32:955–962CrossRef Malouf PA, Descallar J, Berney CR (2018) Bilateral totally extraperitoneal (TEP) repair of the ultrasound-diagnosed asymptomatic contralateral inguinal hernia. Surg Endosc 32:955–962CrossRef
28.
Zurück zum Zitat Bradley M, Morgan J, Pentlow B, Roe A (2006) The positive predictive value of diagnostic ultrasound for occult herniae. Ann R Coll Surg Engl 88:165–167CrossRef Bradley M, Morgan J, Pentlow B, Roe A (2006) The positive predictive value of diagnostic ultrasound for occult herniae. Ann R Coll Surg Engl 88:165–167CrossRef
29.
Zurück zum Zitat Robinson P, Hensor E, Lansdown MJ, Ambrose NS, Chapman AH (2006) Inguinofemoral hernia: accuracy of sonography in patients with indeterminate clinical features. AJR Am J Roentgenol 187:1168–1178CrossRef Robinson P, Hensor E, Lansdown MJ, Ambrose NS, Chapman AH (2006) Inguinofemoral hernia: accuracy of sonography in patients with indeterminate clinical features. AJR Am J Roentgenol 187:1168–1178CrossRef
30.
Zurück zum Zitat Vasileff WK, Nekhline M, Kolowich PA, Talpos GB, Eyler WR, van Holsbeeck M (2017) Inguinal hernia in athletes: role of dynamic ultrasound. Sports Health 9:414–421CrossRef Vasileff WK, Nekhline M, Kolowich PA, Talpos GB, Eyler WR, van Holsbeeck M (2017) Inguinal hernia in athletes: role of dynamic ultrasound. Sports Health 9:414–421CrossRef
31.
Zurück zum Zitat Gupta H, Subedi N, Robinson P (2016) Effectiveness of sonography in detecting clinically occult femoral hernias. J Ultrasound Med 35:1675–1679CrossRef Gupta H, Subedi N, Robinson P (2016) Effectiveness of sonography in detecting clinically occult femoral hernias. J Ultrasound Med 35:1675–1679CrossRef
32.
Zurück zum Zitat Roshanaei A, Tahmasebi M, Gharibvand MM, Askari M (2016) The accuracy of ultrasound in detecting occult inguinal hernia in patients with inconclusive clinical findings, compared with surgical results. Int J Pharm Technol 8:1 Roshanaei A, Tahmasebi M, Gharibvand MM, Askari M (2016) The accuracy of ultrasound in detecting occult inguinal hernia in patients with inconclusive clinical findings, compared with surgical results. Int J Pharm Technol 8:1
33.
Zurück zum Zitat Brandel DW, Girish G, Brandon CJ, Dong Q, Yablon C, Jamadar DA (2016) Role of sonography in clinically occult femoral hernias. J Ultrasound Med 35:121–128CrossRef Brandel DW, Girish G, Brandon CJ, Dong Q, Yablon C, Jamadar DA (2016) Role of sonography in clinically occult femoral hernias. J Ultrasound Med 35:121–128CrossRef
34.
Zurück zum Zitat Lee RK, Griffith JF, Ng WH (2015) High accuracy of ultrasound in diagnosing the presence and type of groin hernia. J Clin Ultrasound 43:538–547CrossRef Lee RK, Griffith JF, Ng WH (2015) High accuracy of ultrasound in diagnosing the presence and type of groin hernia. J Clin Ultrasound 43:538–547CrossRef
35.
Zurück zum Zitat Kim B, Robinson P, Modi H, Gupta H, Horgan K, Achuthan R (2015) Evaluation of the usage and influence of groin ultrasound in primary and secondary healthcare settings. Hernia 19:367–371CrossRef Kim B, Robinson P, Modi H, Gupta H, Horgan K, Achuthan R (2015) Evaluation of the usage and influence of groin ultrasound in primary and secondary healthcare settings. Hernia 19:367–371CrossRef
36.
Zurück zum Zitat Palumbo VD, Tomasello G, Bruno A et al (2014) The value of diagnostic ultrasound for detecting occult inguinal hernia in patients with groin pain. Acta Med Mediterr 30:2 Palumbo VD, Tomasello G, Bruno A et al (2014) The value of diagnostic ultrasound for detecting occult inguinal hernia in patients with groin pain. Acta Med Mediterr 30:2
37.
Zurück zum Zitat Miller J, Cho J, Michael MJ, Saouaf R, Towfigh S (2014) Role of imaging in the diagnosis of occult hernias. JAMA Surg 149:1077–1080CrossRef Miller J, Cho J, Michael MJ, Saouaf R, Towfigh S (2014) Role of imaging in the diagnosis of occult hernias. JAMA Surg 149:1077–1080CrossRef
38.
Zurück zum Zitat Alabraba E, Psarelli E, Meakin K et al (2014) The role of ultrasound in the management of patients with occult groin hernias. Int J Surg 12:918–922CrossRef Alabraba E, Psarelli E, Meakin K et al (2014) The role of ultrasound in the management of patients with occult groin hernias. Int J Surg 12:918–922CrossRef
39.
Zurück zum Zitat Grant T, Neuschler E, Hartz W 3rd (2011) Groin pain in women: use of sonography to detect occult hernias. J Ultrasound Med 30:1701–1707CrossRef Grant T, Neuschler E, Hartz W 3rd (2011) Groin pain in women: use of sonography to detect occult hernias. J Ultrasound Med 30:1701–1707CrossRef
40.
Zurück zum Zitat Højer AM, Rygaard H, Jess P (1997) CT in the diagnosis of abdominal wall hernias: a preliminary study. Eur Radiol 7:1416–1418CrossRef Højer AM, Rygaard H, Jess P (1997) CT in the diagnosis of abdominal wall hernias: a preliminary study. Eur Radiol 7:1416–1418CrossRef
41.
Zurück zum Zitat Jaffe TA, O'Connell MJ, Harris JP, Paulson EK, Delong DM (2005) MDCT of abdominal wall hernias: is there a role for Valsalva's maneuver? AJR Am J Roentgenol 184:847–851CrossRef Jaffe TA, O'Connell MJ, Harris JP, Paulson EK, Delong DM (2005) MDCT of abdominal wall hernias: is there a role for Valsalva's maneuver? AJR Am J Roentgenol 184:847–851CrossRef
42.
Zurück zum Zitat Ng TT, Hamlin JA, Kahn AM (2009) Herniography: analysis of its role and limitations. Hernia 13:7–11CrossRef Ng TT, Hamlin JA, Kahn AM (2009) Herniography: analysis of its role and limitations. Hernia 13:7–11CrossRef
43.
Zurück zum Zitat Jacobson JA, Khoury V, Brandon CJ (2015) ultrasound of the groin: techniques, pathology, and pitfalls. AJR Am J Roentgenol 205:513–523CrossRef Jacobson JA, Khoury V, Brandon CJ (2015) ultrasound of the groin: techniques, pathology, and pitfalls. AJR Am J Roentgenol 205:513–523CrossRef
44.
Zurück zum Zitat Gallegos NC, Dawson J, Jarvis M, Hobsley M (1991) Risk of strangulation in groin hernias. Br J Surg 78:1171–1173CrossRef Gallegos NC, Dawson J, Jarvis M, Hobsley M (1991) Risk of strangulation in groin hernias. Br J Surg 78:1171–1173CrossRef
45.
Zurück zum Zitat Burkhardt JH, Arshanskiy Y, Munson JL, Scholz FJ (2011) Diagnosis of inguinal region hernias with axial CT: the lateral crescent sign and other key findings. Radiographics 31:E1–E12CrossRef Burkhardt JH, Arshanskiy Y, Munson JL, Scholz FJ (2011) Diagnosis of inguinal region hernias with axial CT: the lateral crescent sign and other key findings. Radiographics 31:E1–E12CrossRef
46.
Zurück zum Zitat de Groot JA, Dendukuri N, Janssen KJ et al (2012) Adjusting for partial verification or workup bias in meta-analyses of diagnostic accuracy studies. Am J Epidemiol 175:847–853CrossRef de Groot JA, Dendukuri N, Janssen KJ et al (2012) Adjusting for partial verification or workup bias in meta-analyses of diagnostic accuracy studies. Am J Epidemiol 175:847–853CrossRef
47.
Zurück zum Zitat Vecchio TJ (1966) Predictive value of a single diagnostic test in unselected populations. N Engl J Med 274:1171–1173CrossRef Vecchio TJ (1966) Predictive value of a single diagnostic test in unselected populations. N Engl J Med 274:1171–1173CrossRef
48.
Zurück zum Zitat Terrin N, Schmid CH, Lau J (2005) In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias. J Clin Epidemiol 58:894–901CrossRef Terrin N, Schmid CH, Lau J (2005) In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias. J Clin Epidemiol 58:894–901CrossRef
Metadaten
Titel
Ultrasonography in diagnosing clinically occult groin hernia: systematic review and meta-analysis
verfasst von
Robert M. Kwee
Thomas C. Kwee
Publikationsdatum
14.05.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 11/2018
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-018-5489-9

Weitere Artikel der Ausgabe 11/2018

European Radiology 11/2018 Zur Ausgabe

Mammakarzinom: Brustdichte beeinflusst rezidivfreies Überleben

26.05.2024 Mammakarzinom Nachrichten

Frauen, die zum Zeitpunkt der Brustkrebsdiagnose eine hohe mammografische Brustdichte aufweisen, haben ein erhöhtes Risiko für ein baldiges Rezidiv, legen neue Daten nahe.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.