Erschienen in:
01.02.2005 | Short Communication
Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report
verfasst von:
Isabel M. Oberacher-Velten, Jost B. Jonas, Anselm Jünemann, Barbara Schmidt
Erschienen in:
Graefe's Archive for Clinical and Experimental Ophthalmology
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Ausgabe 2/2005
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Abstract
Background
Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis.
Patient
A 31-year-old man presented with bilateral optic neuropathy, disc edema, and unilateral tonic pupil, which were found to be associated with acute HHV-6 infection. The patient had been suffering from juvenile diabetes for 5 years. One week after onset of intravenous antiviral therapy with foscarnet, disc edema subsided, and tonic pupil reaction was no longer detectable.
Conclusions
HHV-6 infection may play a role as a causative agent in patients with optic neuropathy and tonic pupil.