Erschienen in:
01.04.2009 | Original Article
Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity
verfasst von:
N. Kearney, L. McCann, J. Norrie, L. Taylor, P. Gray, M. McGee-Lennon, M. Sage, M. Miller, R. Maguire
Erschienen in:
Supportive Care in Cancer
|
Ausgabe 4/2009
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Abstract
Objectives
To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.
Design
A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.
Setting
Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.
Participants
One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.
Interventions
A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©).
Main outcome measures
Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea).
Results
There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand–foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).
Conclusion
The study demonstrates that ASyMS© can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.