Skip to main content
Erschienen in: Supportive Care in Cancer 11/2019

15.03.2019 | Original Article

Feasibility of a mindful yoga program for women with metastatic breast cancer: results of a randomized pilot study

verfasst von: Laura S. Porter, James W. Carson, Maren Olsen, Kimberly M. Carson, Linda Sanders, Lee Jones, Kelly Westbrook, Francis J. Keefe

Erschienen in: Supportive Care in Cancer | Ausgabe 11/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Patients with metastatic breast cancer (MBC) experience high levels of symptoms. Yoga interventions have shown promise for improving cancer symptoms but have rarely been tested in patients with advanced disease. This study examined the acceptability of a comprehensive yoga program for MBC and the feasibility of conducting a randomized trial testing the intervention.

Methods

Sixty-three women with MBC were randomized with a 2:1 allocation to yoga or a support group comparison condition. Both interventions involved eight weekly group sessions. Feasibility was quantified using rates of accrual, attrition, and session attendance. Acceptability was assessed with a standardized self-report measure. Pain, fatigue, sleep quality, psychological distress, mindfulness, and functional capacity were assessed at baseline, post-intervention, and 3 and 6 months post-intervention.

Results

We met goals for accrual and retention, with 50% of eligible patients enrolled and 87% of randomized participants completing post-intervention surveys. Sixty-five percent of women in the yoga condition and 90% in the support group attended ≥ 4 sessions. Eighty percent of participants in the yoga condition and 65% in the support group indicated that they were highly satisfied with the intervention. Following treatment, women in the yoga intervention had modest improvements in some outcomes; however, overall symptom levels were low for women in both conditions.

Conclusions

Findings suggest that the yoga intervention content was highly acceptable to patients with MBC, but that there are challenges to implementing an intervention involving eight group-based in-person sessions. Alternative modes of delivery may be necessary to reach patients most in need of intervention.
Literatur
2.
Zurück zum Zitat Irvin WJ, Muss H, Mayer D (2011) Symptom management in metastatic breast cancer. Oncologist 16(9):1203–1214CrossRef Irvin WJ, Muss H, Mayer D (2011) Symptom management in metastatic breast cancer. Oncologist 16(9):1203–1214CrossRef
5.
Zurück zum Zitat Buffart LM, van Uffelen JGZ, Riphagen II, Brug J, van Mechelen W, Brown WJ, Chinapaw MJM (2012) Physical and psychosocial benefits of yoga in cancer patients and survivors, a systematic review and meta-analysis of randomized controlled trials. BMC Cancer 12:559CrossRef Buffart LM, van Uffelen JGZ, Riphagen II, Brug J, van Mechelen W, Brown WJ, Chinapaw MJM (2012) Physical and psychosocial benefits of yoga in cancer patients and survivors, a systematic review and meta-analysis of randomized controlled trials. BMC Cancer 12:559CrossRef
7.
Zurück zum Zitat Clark D (2002) Between hope and acceptance: the medicalisation of dying. BMJ 324:905–907CrossRef Clark D (2002) Between hope and acceptance: the medicalisation of dying. BMJ 324:905–907CrossRef
9.
Zurück zum Zitat Carson JW, Carson KM, Porter LS, Keefe FJ, Seewaldt VL (2009) Yoga of Awareness program for menopausal symptoms in breast cancer survivors: results from a randomized trial. Support Care Cancer 17(10):1301–1309CrossRef Carson JW, Carson KM, Porter LS, Keefe FJ, Seewaldt VL (2009) Yoga of Awareness program for menopausal symptoms in breast cancer survivors: results from a randomized trial. Support Care Cancer 17(10):1301–1309CrossRef
10.
Zurück zum Zitat Carson JW, Carson KM, Jones KD, Bennett RM, Wright CL, Mist SD (2010) A pilot randomized controlled trial of the Yoga of Awareness program in the management of fibromyalgia. Pain 151(2):530–539CrossRef Carson JW, Carson KM, Jones KD, Bennett RM, Wright CL, Mist SD (2010) A pilot randomized controlled trial of the Yoga of Awareness program in the management of fibromyalgia. Pain 151(2):530–539CrossRef
11.
Zurück zum Zitat Carson JW, Carson KM, Jones KD, Mist SD, Bennett RM (2012) Follow-up of Yoga of Awareness for fibromyalgia: results at 3 months and replication in the wait-list group. Clin J Pain 28(9):804–813CrossRef Carson JW, Carson KM, Jones KD, Mist SD, Bennett RM (2012) Follow-up of Yoga of Awareness for fibromyalgia: results at 3 months and replication in the wait-list group. Clin J Pain 28(9):804–813CrossRef
12.
Zurück zum Zitat Carson J, Carson KM, Porter LS, Keefe FJ, Shaw H, Miller JM (2007) Yoga for women with metastatic breast cancer: results from a pilot study. J Pain Symptom Manag 33(3):331–341CrossRef Carson J, Carson KM, Porter LS, Keefe FJ, Shaw H, Miller JM (2007) Yoga for women with metastatic breast cancer: results from a pilot study. J Pain Symptom Manag 33(3):331–341CrossRef
13.
Zurück zum Zitat Nguyen TD, Attkisson CC, Stegner BL (1983) Assessment of patient satisfaction: development and refinement of a service evaluation questionnaire. Eval Prog Plan 6:299–314CrossRef Nguyen TD, Attkisson CC, Stegner BL (1983) Assessment of patient satisfaction: development and refinement of a service evaluation questionnaire. Eval Prog Plan 6:299–314CrossRef
15.
Zurück zum Zitat Cleeland CS, Ryan KM (1994) Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singap 23:129–138PubMed Cleeland CS, Ryan KM (1994) Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singap 23:129–138PubMed
17.
Zurück zum Zitat Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193–213CrossRef Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 28(2):193–213CrossRef
18.
Zurück zum Zitat Carpenter JS, Andrykowski MA (1998) Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 45(1):5–13CrossRef Carpenter JS, Andrykowski MA (1998) Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 45(1):5–13CrossRef
19.
Zurück zum Zitat Herrmann C (1997) International experiences with the Hospital Anxiety and Depression Scale—a review of validation data and clinical results. J Psychosom Res 42(1):17–41CrossRef Herrmann C (1997) International experiences with the Hospital Anxiety and Depression Scale—a review of validation data and clinical results. J Psychosom Res 42(1):17–41CrossRef
20.
Zurück zum Zitat Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370CrossRef Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370CrossRef
22.
Zurück zum Zitat Baer RA, Smith GT, Lykins E, Button D, Krietemeyer J, Sauer S, Walsh E, Duggan D, Williams JMG (2008) Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment 15(3):329–342CrossRef Baer RA, Smith GT, Lykins E, Button D, Krietemeyer J, Sauer S, Walsh E, Duggan D, Williams JMG (2008) Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment 15(3):329–342CrossRef
24.
Zurück zum Zitat Breitbart W, Rosenfeld B, Gibson C, Pessin H, Poppito S, Nelson C, Tomarken A, Timm AK, Berg A, Jacobson C, Sorger B, Abbey J, Olden M (2010) Meaning-centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial. Psycho-Oncology 19(1):21–28CrossRef Breitbart W, Rosenfeld B, Gibson C, Pessin H, Poppito S, Nelson C, Tomarken A, Timm AK, Berg A, Jacobson C, Sorger B, Abbey J, Olden M (2010) Meaning-centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial. Psycho-Oncology 19(1):21–28CrossRef
25.
Zurück zum Zitat Helgeson VS, Cohen S, Schulz R, Yasko J (1999) Education and peer discussion group interventions and adjustment to breast cancer. Arch Gen Psychiatry 56(4):340–347CrossRef Helgeson VS, Cohen S, Schulz R, Yasko J (1999) Education and peer discussion group interventions and adjustment to breast cancer. Arch Gen Psychiatry 56(4):340–347CrossRef
26.
Zurück zum Zitat Keefe FJ, Caldwell DS, Baucom D, Salley A, Robinson E, Timmons K, Beaupre P, Weisberg J, Helms M (1996) Spouse-assisted coping skills training in the management of osteoarthritic knee pain. Arthritis Care Res 9(4):279–291CrossRef Keefe FJ, Caldwell DS, Baucom D, Salley A, Robinson E, Timmons K, Beaupre P, Weisberg J, Helms M (1996) Spouse-assisted coping skills training in the management of osteoarthritic knee pain. Arthritis Care Res 9(4):279–291CrossRef
27.
Zurück zum Zitat Kraemer HC, Mintz J, Noda A, Tinklenberg J, Yesavage JA (2006) Caution regarding the use of pilot studies to guide power calculations for study proposals. Arch Gen Psychiatry 63(5):484–489CrossRef Kraemer HC, Mintz J, Noda A, Tinklenberg J, Yesavage JA (2006) Caution regarding the use of pilot studies to guide power calculations for study proposals. Arch Gen Psychiatry 63(5):484–489CrossRef
Metadaten
Titel
Feasibility of a mindful yoga program for women with metastatic breast cancer: results of a randomized pilot study
verfasst von
Laura S. Porter
James W. Carson
Maren Olsen
Kimberly M. Carson
Linda Sanders
Lee Jones
Kelly Westbrook
Francis J. Keefe
Publikationsdatum
15.03.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 11/2019
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-019-04710-7

Weitere Artikel der Ausgabe 11/2019

Supportive Care in Cancer 11/2019 Zur Ausgabe

Bei seelischem Stress sind Checkpoint-Hemmer weniger wirksam

03.06.2024 NSCLC Nachrichten

Wie stark Menschen mit fortgeschrittenem NSCLC von einer Therapie mit Immun-Checkpoint-Hemmern profitieren, hängt offenbar auch davon ab, wie sehr die Diagnose ihre psychische Verfassung erschüttert

Antikörper mobilisiert Neutrophile gegen Krebs

03.06.2024 Onkologische Immuntherapie Nachrichten

Ein bispezifischer Antikörper formiert gezielt eine Armee neutrophiler Granulozyten gegen Krebszellen. An den Antikörper gekoppeltes TNF-alpha soll die Zellen zudem tief in solide Tumoren hineinführen.

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.