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03.01.2021 | Original Article

Porcine circovirus genotypes and their copathogens in pigs with respiratory disease in southern provinces of Vietnam

verfasst von: Phat Xuan Dinh, Minh Nam Nguyen, Hien The Nguyen, Vu Hoang Tran, Quy Dinh Tran, Kim Hoang Dang, Dai Tan Vo, Hien Thanh Le, Nam Thi Thu Nguyen, Toan Tat Nguyen, Duy Tien Do

Erschienen in: Archives of Virology | Ausgabe 2/2021

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Abstract

This study was conducted to investigate the genetic diversity of porcine circovirus type 2 (PCV2) and its coinfecting pathogens in pigs with respiratory disease in Vietnam. Samples from 127 clinical cases were obtained from different southern provinces of Vietnam from January 2018 to January 2020 for PCR and sequence analysis. The infection rate of PCV2 was 78.8%, and the major pathogens found in coinfections with PCV2 were porcine reproductive and respiratory syndrome virus, Mycoplasma hyopneumoniae, and Haemophilus parasuis. Forty-three PCV2-positive clinical samples were selected for amplification and sequencing of the ORF2 region. Phylogenetic analysis of PCV2 ORF2 showed that five of the sequences belonged to PCV2b (11.6%) and 38 belonged to PCV2d (88.4%), indicating that PCV2d strains were predominant in southern provinces of Vietnam. Alignment of the predicted amino acid sequences of the PCV2 capsid protein revealed polymorphic sites in the antibody recognition regions. This study demonstrates the prevalence of the PCV2d genotype in southern Vietnam and presents a comprehensive overview of the coinfecting pathogens associated with PCV2 in young pigs with respiratory disease.

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Titel: Porcine circovirus genotypes and their copathogens in pigs with respiratory disease in southern provinces of Vietnam
verfasst von: Phat Xuan Dinh
Minh Nam Nguyen
Hien The Nguyen
Vu Hoang Tran
Quy Dinh Tran
Kim Hoang Dang
Dai Tan Vo
Hien Thanh Le
Nam Thi Thu Nguyen
Toan Tat Nguyen
Duy Tien Do
Publikationsdatum: 03.01.2021
Verlag: Springer Vienna
Erschienen in: Archives of Virology / Ausgabe 2/2021
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-020-04878-y

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Porcine circovirus genotypes and their copathogens in pigs with respiratory disease in southern provinces of Vietnam

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