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Journal of Bone and Mineral Metabolism

Erschienen in:

01.09.2010 | Case Report

Mediastinal parathyroid carcinoma presenting with severe skeletal manifestations

verfasst von: Tuck Y. Yong, Jordan Y. Z. Li

Erschienen in: Journal of Bone and Mineral Metabolism | Ausgabe 5/2010

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Abstract

Parathyroid carcinoma is a rare malignancy, accounting for about 1% of primary hyperparathyroidism. We report the case of a 23-year-old man who presented with poorly united mid-shaft fracture of the left femur with severe hypercalcaemia in the setting of 99 mTc sestamibi-avid lesions in the mediastinal and thoracic vertebrae. The patient underwent surgery, and histopathology revealed a low-grade parathyroid carcinoma. After surgery, the patient developed severe hungry bone syndrome requiring intensive calcium, magnesium and active vitamin D supplementation. A review of the literature was undertaken with regards to mediastinal parathyroid carcinoma, management of refractory hypercalcaemia in this setting and hungry bone syndrome.

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Titel: Mediastinal parathyroid carcinoma presenting with severe skeletal manifestations
verfasst von: Tuck Y. Yong
Jordan Y. Z. Li
Publikationsdatum: 01.09.2010
Verlag: Springer Japan
Erschienen in: Journal of Bone and Mineral Metabolism / Ausgabe 5/2010
Print ISSN: 0914-8779
Elektronische ISSN: 1435-5604
DOI: https://doi.org/10.1007/s00774-010-0173-4

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