nach oben

Lasers in Medical Science

Erschienen in:

01.11.2012 | Brief Report

Effect of irradiation with red and infrared laser in the treatment of oral mucositis

A pilot study with patients undergoing chemotherapy with 5-FU

verfasst von: C. B. Cunha, F. P. Eduardo, D. M. Zezell, L. M. Bezinelli, P. P. L. Shitara, L. Correa

Erschienen in: Lasers in Medical Science | Ausgabe 6/2012

Einloggen, um Zugang zu erhalten

Excerpt

Oral mucositis (OM) is considered the cause of high morbidity and one of the main side effects of chemotherapy for antineoplastic treatment. The impact of OM on the patient’s health ranges from worsening quality of life during chemotherapy through to increased treatment costs [1, 2]. OM refers to lesions of the oral mucosa that vary from erythematous to ulcerative, and may result in various degrees of signs and symptoms, such as burning and pain when swallowing and speaking. These symptoms predispose the patient to nutritional disturbances and ulcerations may increase the risk of opportunist infections [2]. …

Vera-Llonch M, Oster G, Ford CM, Lu J, Sonis S (2007) Oral mucositis and autologous hematopoietic stem-cell transplantation following high-dose melfalan conditioning for multiple myeloma. Supportive Oncol 5:231–235

Elting LS, Keefe DM, Sonis ST, Garden AS, Spijkervet FK, Barash A, Tishler RB, Canty TP, Kudrimoti MK, Vera-Llonch M (2008) Burden of illness Head and Neck writing committee. Patient- reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer 113(10):2704–2713PubMedCrossRef

Chansky K, Benedetti J, Macdonald JS (2005) Differences between men and women treated with 5-fluoracil therapy for colorectal carcinoma. Cancer Care 15(6):1665–1671

Tebbutt NC, Norman AR, Cunningham D, Allen M, Chau I, Oates J, Hill M (2003) Analysis of the time course and prognostic factors determining toxicity due to infused fluorouracil. Br J Cancer 19;88(10):1510–1515

Alterio D, Jereczec-Fossa BA, Fiore MR, Piperno G, Nassarin M, Orechia R (2007) Cancer treatment-induced oral mucositis. Anticancer Res 27:1105–1126PubMed

Clarkson JE, Worthington HV, Furness S, McCabe M, Khalid T, Meyer S (2010) Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev 4(8):CD001973

Bensadoun RJ (2006) Low level LASER therapy (LLLT): a new paradigm in the management of cancer therapy-induced mucositis. Indian J Med Res 124:375–378PubMed

Antunes HS, Azevedo AM, Silva-Bouzas LF (2009) Low-power laser in the preventions of induces oral mucositis in the bone transplantation patients: a randomized trial. Blood 109:225–255

Schubert MM, Eduardo FP, Guthrie KA, Franquin JC, Bensadoun RJ, Migliorati CA, Lloid CM, Eduardo CP, Walter NF, Marques MM, Hamdi M (2007) A phase III randomized double-blind placebo-controlled clinical trial to determine the efficacy of low level laser therapy for the prevention of oral mucositis in patients undergoing hematopoietic cell transplantation. Support Care Cancer 15(10):1145–1154PubMedCrossRef

10.

Eduardo FP, Bezinelli L, Luiz AC, Correa L, Vogel C, Eduardo CP (2008) Severity of oral mucositis in Patients undergoing Hematopoietic Cell transplantation and an oral laser Phototherapy protocol: a survey of 30 patients. Photomed Laser Surg 26:1–7CrossRef

11.

Lopes NNF, Plaper M, Chavantes MC, Lalla RV, Yoshimura EM, Alves MTS (2009) Cyclooxygenase-2 and vascular endothelial factor expression in 5-fluoracil-induced oral mucositis in hamsters: evaluation of two low-intensity laser protocols. Support Care Cancer 17(11):1409–1415PubMedCrossRef

12.

França CM, Nunez SC, Prates RA, Noborikawa E, Faria RM, Ribeiro MS (2009) Low-intensity red laser on the prevention and treatment of induced-oral mucositis in hamsters. J Photochem Photobiol B 94:25–31PubMedCrossRef

13.

Chow R, Armati P, Laakso EL, Bjordal JM, Baxter GD (2011) Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review. Photomed Laser Surg 29:365–381.

14.

Kuhn A, Porto FA, Miraglia P, Brunetto AL (2009) Low-level infrared laser therapy in chemotherapy-induced oral mucositis: a randomized placebo-controlled trial in children. J Pediatr Hematol Oncol 31(1):33–37PubMedCrossRef

15.

Monopoli M, Woo S, Valley M, Sonis S. A site-based scoring system of chemotherapy-induced oral mucositis in bone marrow transplant recipients. Presented at the Sixth Annual Meeting of the Society of Oral Oncology. Keystone, CO; August 1, 1991. Abstract

16.

Enwemeka CS (2009) Intricacies of dose in laser phototherapy for tissue repair and pain relief. Photomed Laser Surg 27(3):387–393PubMedCrossRef

17.

Sonis ST (2010) New thoughts on the initiation of mucositis. Oral Dis 16(7):597–600PubMedCrossRef

18.

Reddy GK (2004) Photobiological basis and clinical role of low-intensity lasers in biology and medicine. J Clin Laser Med Surg 22(2):141–150PubMedCrossRef

19.

Cauwels RG, Martens LC (2011) Low level laser therapy in oral mucositis: a pilot study. Eur Arch Paediatr Dent 12(2):118–123PubMed

20.

Arora H, Pai KM, Maiya A, Vidyasagar MS, Rajeev A. Efficacy of He–Ne Laser in the prevention and treatment of radiotherapy-induced oral mucositis in oral cancer patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008 105(2):180–186, 186.e1

21.

Silva GB, Mendonça EF, Bariani C, Antunes HS, Silva MA (2011) The prevention of induced oral mucositis with low-level laser therapy in bone marrow transplantation patients: a randomized clinical trial. Photomed Laser Surg 29(1):27–31PubMedCrossRef

22.

Raber-Durlacher JE, Elad S, Barach A (2010) Oral mucositis—review. Oral Oncol 46:452–456PubMedCrossRef

23.

Santos PSS, Coracin FL, Barros JC, Dulley FL, Nunes FD, Magalhães MG (2010) Impact of oral care prior to HSCT on the severity and clinical outcomes of oral mucositis. Clin Transplant 10:1–4CrossRef

24.

Papadeas E, Naxakis S, Riga M (2007) Prevention of 5-fluorouracil — related stomatitis by oral cryotherapy: a randomized controlled study. Eur J Oncol Nurs 11:60–65PubMedCrossRef

Titel: Effect of irradiation with red and infrared laser in the treatment of oral mucositis
A pilot study with patients undergoing chemotherapy with 5-FU
verfasst von: C. B. Cunha
F. P. Eduardo
D. M. Zezell
L. M. Bezinelli
P. P. L. Shitara
L. Correa
Publikationsdatum: 01.11.2012
Verlag: Springer-Verlag
Erschienen in: Lasers in Medical Science / Ausgabe 6/2012
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-012-1089-0

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Effect of irradiation with red and infrared laser in the treatment of oral mucositis

A pilot study with patients undergoing chemotherapy with 5-FU

Excerpt

Live-Webinar "Urologie und Sexualmedizin in der Praxis"

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 6/2012

Low-level laser therapy for oral mucous membrane pemphigoid

Treatment of persistent Mongolian spots with Q-switched alexandrite laser

Comparing an optical parametric oscillator (OPO) as a viable alternative for mid-infrared tissue ablation with a free electron laser (FEL)

Custom-made, root-analogue direct laser metal forming implant: a case report

Effect of low-level laser therapy on proliferation, differentiation, and adhesion of steroid-treated osteoblasts

Photodynamic inactivation of biofilms formed by Candida spp., Trichosporon mucoides, and Kodamaea ohmeri by cationic nanoemulsion of zinc 2,9,16,23-tetrakis(phenylthio)-29H, 31H-phthalocyanine (ZnPc)