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01.01.2014 | Original Article

Temperature imaging of laser-induced thermotherapy (LITT) by MRI: evaluation of different sequences in phantom

verfasst von: Babak Bazrafshan, Frank Hübner, Parviz Farshid, Renate Hammerstingl, Jijo Paul, Vitali Vogel, Werner Mäntele, Thomas J. Vogl

Erschienen in: Lasers in Medical Science | Ausgabe 1/2014

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Abstract

The purpose of this study was to evaluate magnetic resonance (MR) temperature imaging of the laser-induced thermotherapy (LITT) comparing the proton resonance frequency (PRF) and T ₁ thermometry methods. LITT was applied to a liver-mimicking acrylamide gel phantom. Temperature rise up to 70 °C was measured using a MR-compatible fiber-optic thermometer. MR imaging was performed by a 1.5-T scanner utilizing fast gradient echo sequences including a segmented echo planar imaging (seg-EPI) sequence for PRF and the following sequences for T ₁ method: fast low-angle shot (FLASH), inversion recovery turbo flash (IRTF), saturation recovery turbo flash (SRTF), and true fast imaging (TRUFI). Temperature-induced change of the pixel values in circular regions of interest, selected on images under the temperature probe tip, was recorded. For each sequence, a calibration constant could be determined to be −0.0088 ± 0.0002 ppm °C⁻¹ (EPI), −1.15 ± 0.03 °C⁻¹ (FLASH), −1.49 ± 0.03 °C⁻¹ (IRTF), −1.21 ± 0.03 °C⁻¹ (SRTF), and −2.52 ± 0.12 °C⁻¹ (TRUFI). These constants were evaluated in further LITT experiments in phantom comparing the calculated temperatures with the fiber optic-measured ones; temperature precisions of 0.60 °C (EPI), 0.81 °C (FLASH), 1.85 °C (IRTF), 1.95 °C (SRTF), and 3.36 °C (TRUFI) were obtained. Furthermore, performing the Bland–Altman analysis, temperature accuracy was determined to be 0.23 °C (EPI), 0.31 °C (FLASH), 1.66 °C (IRTF), 1.19 °C (SRTF), and 3.20 °C (TRUFI). In conclusion, the seg-EPI sequence was found to be more convenient for MR temperature imaging of LITT due to its relatively high precision and accuracy. Among the T ₁ method sequences, FLASH showed the highest accuracy and robustness.

40 vol% acrylamide/bisacrylamide; mixture ratio 29:1

59 wt%; microsphere diameter, 0.45–3.51 μm

0.5 mmol gadopentetate dimeglumine (Gd-DTPA) in 1 ml Magnevist solution

10 wt% solution; diluted in distilled water

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Titel: Temperature imaging of laser-induced thermotherapy (LITT) by MRI: evaluation of different sequences in phantom
verfasst von: Babak Bazrafshan
Frank Hübner
Parviz Farshid
Renate Hammerstingl
Jijo Paul
Vitali Vogel
Werner Mäntele
Thomas J. Vogl
Publikationsdatum: 01.01.2014
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 1/2014
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-013-1306-5

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Temperature imaging of laser-induced thermotherapy (LITT) by MRI: evaluation of different sequences in phantom

Abstract

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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