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Modern Rheumatology

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01.05.2013 | Case Report

Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis

verfasst von: Mihoko Shibuya, Keishi Fujio, Kaoru Morita, Hiroaki Harada, Hiroko Kanda, Kazuhiko Yamamoto

Erschienen in: Modern Rheumatology | Ausgabe 3/2013

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Abstract

A 69-year-old man with sensorineural hearing loss and iritis was diagnosed with atypical Cogan’s syndrome. He had several systematic manifestations: aortitis, meningitis, panniculitis and seronegative arthritis. Remission induced by treatment with high doses of prednisolone was followed by relapse within 1 year. Although his condition was resistant to various immunosuppressive drugs, including methotrexate, cyclosporine, azathioprine and adalimumab, his symptoms, inflammatory response and quality of life measures were successfully improved by tocilizumab, a humanized anti-interleukin-6 receptor antibody.

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Titel: Successful treatment with tocilizumab in a case of Cogan’s syndrome complicated with aortitis
verfasst von: Mihoko Shibuya
Keishi Fujio
Kaoru Morita
Hiroaki Harada
Hiroko Kanda
Kazuhiko Yamamoto
Publikationsdatum: 01.05.2013
Verlag: Springer Japan
Erschienen in: Modern Rheumatology / Ausgabe 3/2013
Print ISSN: 1439-7595
Elektronische ISSN: 1439-7609
DOI: https://doi.org/10.1007/s10165-012-0691-0

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