Preface 2014
Contents
I. Clinical factors of esophageal cancer patients treated in 2014
1. Institution-registered cases in 2014
2. Patient background
Table 1 Age and gender
Age | Male | Female | Cases (%) |
---|---|---|---|
≤ 29 | 20 | 4 | 24 (0.3) |
30–39 | 22 | 7 | 29 (0.3) |
40–49 | 179 | 74 | 253 (2.8) |
50–59 | 995 | 230 | 1225 (13.6) |
60–69 | 2908 | 482 | 3390 (37.6) |
70–79 | 2788 | 432 | 3220 (35.7) |
80–89 | 685 | 148 | 833 (9.2) |
90 ≤ | 34 | 18 | 52 (0.6) |
Total | 7631 | 1395 | 9026 |
Table 2 Performed treatment
Treatments | Cases (%) |
---|---|
Surgery | 5355 (59.3) |
Esophagectomy | 5204 (57.7) |
Palliative surgery | 151 (1.7) |
Chemotherapy and/or radiotherapy | 4835 (53.6) |
Endoscopic treatment | 1529 (16.9) |
Table 3 Tumor location
Location of tumor | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
Cervical | 43 (2.8) | 185 (3.6) | 6 (4.0) | 305 (6.3) | 436 (4.8) |
Upper thoracic | 164 (10.7) | 598 (11.5) | 36 (23.8) | 738 (15.3) | 1160 (12.9) |
Middle thoracic | 838 (54.7) | 2386 (45.8) | 66 (43.7) | 2180 (45.1) | 4200 (46.5) |
Lower thoracic | 378 (24.7) | 1528 (29.4) | 35 (23.2) | 1296 (26.8) | 2451 (27.2) |
EG | 68 (4.4) | 378 (7.3) | 7 (4.6) | 214 (4.4) | 531 (5.9) |
E = G | 24 (1.6) | 64 (1.2) | 30 (0.6) | 94 (1.0) | |
GE | 7 (0.5) | 62 (1.2) | 40 (0.8) | 85 (0.9) | |
Unknown | 7 (0.5) | 3 (0.1) | 1 (0.7) | 32 (0.7) | 69 (0.8) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
Table 4 Histologic types of biopsy specimens
Histologic types | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
Squamous cell carcinoma | 1314 (85.9) | 4567 (87.8) | 143 (94.7) | 4450 (92.0) | 7938 (87.9) |
Squamous cell carcinoma | 993 (64.2) | 2484 (47.7) | 93 (61.6) | 2601 (53.8) | 4819 (53.4) |
Well differentiated | 104 (6.8) | 427 (8.2) | 12 (7.9) | 320 (6.6) | 640 (7.1) |
Moderately differentiated | 172 (11.2) | 1234 (23.7) | 29 (19.2) | 1098 (22.7) | 1807 (20.0) |
Poorly differentiated | 45 (2.9) | 422 (8.1) | 9 (6.0) | 431 (8.9) | 672 (7.4) |
Adenocarcinoma | 41 (2.7) | 372 (7.1) | 3 (2.0) | 199 (4.1) | 492 (5.5) |
Barrett's carcinoma | 42 (2.7) | 96 (1.8) | 1 (0.7) | 25 (0.5) | 144 (1.6) |
Adenosquamous carcinoma | 1 (0.1) | 10 (0.2) | 7 (0.1) | 18 (0.2) | |
Mucoepidermoid carcinoma | 2 (0.0) | 1 (0.0) | 3 (0.0) | ||
Basaloid carcinoma | 4 (0.3) | 32 (0.6) | 19 (0.4) | 41 (0.5) | |
Neuroendocrine tumor | 1 (0.0) | 1 (0.0) | |||
Neuroendocrine carcinoma | 1 (0.1) | 16 (0.3) | 34 (0.7) | 41 (0.5) | |
Undifferentiated carcinoma | 1 (0.1) | 4 (0.1) | 2 (0.0) | 5 (0.3) | |
Malignant melanoma | 18 (0.3) | 9 (0.2) | 24 (0.3) | ||
Carcinosarcoma | 1 (0.1) | 22 (0.4) | 12 (0.2) | 28 (0.3) | |
GIST | 7 (0.1) | 2 (0.0) | 8 (0.1) | ||
Adenoid cystic carcinoma | 1 (0.0) | 1 (0.0) | |||
Nonepithelial tumors | 2 (0.1) | 3 (0.1) | 3 (0.1) | 6 (0.1) | |
Other epithelial tumors | 36 (2.4) | 8 (0.2) | 9 (0.2) | 58 (0.6) | |
Other tumors | 26 (1.7) | 15 (0.3) | 5 (0.1) | 47 (0.5) | |
Unknown | 60 (3.9) | 31 (0.6) | 4 (2.6) | 57 (2.1) | 171 (1.9) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
Table 5 Depth of tumor invasion, cT (UICC TNM 7th)
Clinical T | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
cTX | 28 (1.8) | 17 (0.3) | 4 (2.6) | 57 (1.2) | 144 (1.6) |
cT0 | 17 (1.1) | 7 (0.1) | 3 (0.1) | 30 (0.3) | |
cT1a | 1173 (76.7) | 240 (4.6) | 112 (2.3) | 1469 (16.3) | |
cT1b | 205 (13.4) | 1409 (27.1) | 2 (1.3) | 644 (13.3) | 1858 (20.6) |
cT2 | 9 (0.6) | 867 (16.7) | 5 (3.3) | 667 (13.8) | 1086 (12.0) |
cT3 | 46 (3.0) | 2310 (44.4) | 62 (41.1) | 2367 (49.0) | 3250 (36.0) |
cT4a | 10 (0.7) | 164 (3.2) | 13 (8.6) | 317 (6.6) | 404 (4.5) |
cT4b | 41 (2.7) | 190 (3.7) | 65 (43.0) | 668 (13.8) | 785 (8.7) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
Table 6 Lymph-node metastasis, cN (UICC TNM 7th)
Clinical N | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
cN0 | 1426 (93.3) | 2390 (45.9) | 20 (13.2) | 1310 (27.1) | 4399 (48.7) |
cN1 | 50 (3.3) | 1825 (35.1) | 60 (39.7) | 1914 (39.6) | 2627 (29.1) |
cN2 | 33 (2.2) | 867 (16.7) | 56 (37.1) | 1257 (26.0) | 1567 (17.4) |
cN3 | 20 (1.3) | 122 (2.3) | 15 (9.9) | 354 (7.3) | 433 (4.8) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
Table 7 Distant metastasis, cM (UICC TNM 7th)
Clinical M | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
cM0 | 1494 (97.7) | 5036 (96.8) | 108 (71.5) | 4210 (85.2) | 8148 (90.3) |
cM1 | 35 (2.3) | 168 (3.2) | 43 (28.5) | 715 (14.8) | 878 (9.7) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
Table 8 Clinical stage (UICC TNM 7th)
Clinical stage | Endoscopic treatment | Surgery | Chemotherapy and/or | Total (%) | |
---|---|---|---|---|---|
(%) | Esophagectomy (%) | Palliative surgery (%) | radiotherapy (%) | ||
Stage IA | 1363 (89.1) | 1307 (25.1) | 2 (1.3) | 471 (9.7) | 2899 (32.1) |
Stage IB | 5 (0.3) | 458 (8.8) | 2 (1.3) | 282 (5.8) | 558 (6.2) |
Stage IIA | 10 (0.7) | 531 (10.2) | 6 (4.0) | 400 (8.3) | 649 (7.2) |
Stage IIB | 15 (1.0) | 577 (11.1) | 1 (0.7) | 449 (9.3) | 680 (7.5) |
Stage IIIA | 14 (0.9) | 1195 (23.0) | 21 (13.9) | 1078 (22.3) | 1499 (16.6) |
Stage IIIB | 8 (0.5) | 560 (10.8) | 16 (10.6) | 567 (11.7) | 733 (8.1) |
Stage IIIC | 35 (2.3) | 385 (7.4) | 57 (37.7) | 839 (17.4) | 997 (11.0) |
Stage IV | 35 (2.3) | 168 (3.2) | 43 (28.5) | 715 (14.8) | 878 (9.7) |
Unknown | 44 (2.9) | 23 (0.4) | 3 (2.0) | 34 (0.7) | 133 (1.5) |
Total | 1529 | 5204 | 151 | 4835 | 9026 |
II. Results of endoscopically treated patients in 2014
Table 9 Details of endoscopic treatment for curative intent
Treatment details | Cases (%) |
---|---|
EMR | 104 (7.1) |
EMR + YAG laser | 1 (0.1) |
EMR + MCT/RFA | |
ESD | 1265 (86.0) |
ESD + EMR | 80 (5.4) |
ESD + PDT | |
ESD + YAG laser | 2 (0.1) |
PDT | 3 (0.2) |
YAG laser | 16 (1.1) |
Total | 1471 |
Table 10 Complications of EMR/ESD
Complications of EMR/ESD | Cases (%) |
---|---|
None | 1384 (95.8) |
Perforation | 12 (0.8) |
Bleeding | 3 (0.2) |
Mediastinitis | 5 (0.3) |
Stenosis | 41 (2.8) |
Others | |
Unknown | |
Total | 1445 |
Table 11 Pathologic depth of tumor invasion of EMR/ESD specimens
Pathological depth of tumor invasion (pT) | Cases (%) |
---|---|
pTX | 17 (1.2) |
pT0 | 68 (0.5) |
pT1a | 1127 (82.8) |
pT1b | 238 (15.0) |
pT2 | |
pT3 | 2 (0.1) |
Total | 1452 |
Figure 1 Survival of patients treated with EMR/ESD
Figure 2 Survival of patients treated with EM/ESD according to the pathological depth of tumor invasion, pT (JES 10th)
Figure 3 Survival of patients treated with EMR/ESD according to the lymphatic and venous invasion
III. Results in patients treated with chemotherapy and/or radiotherapy in 2014
Table 12 Dose of irradiation (non-surgically treated cases)
Dose of irradiation | Definitive | Palliative (%) | Recurrence (%) | Others (%) | Total (%) | |
---|---|---|---|---|---|---|
(Gy) | Radiation alone (%) | With chemotherapy (%) | ||||
-29 | 2 (1.2) | 16 (1.7) | 26 (8.4) | 2 (6.3) | 3 (37.5) | 49 (3.3) |
30–39 | 3 (1.8) | 17 (1.8) | 53 (17.1) | 5 (15.6) | 78 (5.6) | |
40–49 | 5 (3.0) | 34 (3.5) | 56 (18.1) | 4 (12.5) | 2 (25.0) | 101 (6.8) |
50–59 | 26 (15.8) | 246 (25.5) | 77 (24.8) | 8 (25.0) | 1 (12.5) | 359 (24.2) |
60–69 | 124 (75.2) | 620 (64.4) | 90 (29.0) | 11 (34.4) | 2 (25.0) | 849 (57.3) |
70- | 4 (2.4) | 28 (2.9) | 5 (1.6) | 2 (.3) | 39 (2.6) | |
Unknown | 1 (0.6) | 2 (0.2) | 3 (1.0) | 6 (0.4) | ||
Total | 165 | 963 | 310 | 32 | 8 | 1481 |
Median (min–max) | 60.0 (10.0–70.0) | 60.0 (2.0–92.0) | 50.0 (2.0–90.0) | 50.4 (8.0–70.0) | 60.0 (50.0–63.4) | 60.0 (2.0–92.0) |
Table 13 Dose of irradiation (surgically treated cases)
Dose of | Preoperative | Postoperative |
---|---|---|
irradiation (Gy) | irradiation (%) | irradiation (%) |
-29 | 12 (3.7) | |
30–39 | 55 (16.9) | 3 (5.0) |
40–49 | 199 (61.0) | 9 (15.0) |
50–59 | 40 (12.3) | 20 (33.3) |
60–69 | 16 (4.9) | 24 (40.0) |
70- | 1 (0.3) | 3 (5.0) |
Unknown | 3 (0.9) | 1 (1.7) |
Total | 326 | 60 |
Median (min—max) | 40.0 (1.8- 70.0) | 54.0 (30.0 – 97.5) |
Figure 4 Survival of patients treated with chemotherapy and/or radiotherapy
Figure 5 Survival of patients treated with definitive chemoradiotherapy according to the clinical stage (UICC TNM 7th)
Figure 6 Survival of patients underwent radiotherapy alone according to the clinical stage ( UICC TNM 7th)
IV. Results in patients who underwent esophagectomy in 2014
Table 14 Treatment modalities of esophagectomy
Treatment modalities | Cases (%) |
---|---|
Esophagectomy alone | 2307 (44.3) |
Esophagectomy + postoperative chemotherapy | 387 (7.4) |
Esophagectomy + postoperative chemoradiotherapy | 109 (2.1) |
Esophagectomy + postoperative radiotherapy | 39 (0.7) |
Preoperative chemotherapy + Esophagectomy | 1784 (34.3) |
Preoperative chemoradiotherapy + Esophagectomy | 335 (6.4) |
Definitive radiotherapy + Esophagectomy | 6 (0.1) |
Definitive chemoradiotherapy + Esophagectomy | 124 (2.4) |
Others | 113 (2.2) |
Total | 5204 |
Table 15 Tumor location
Locations | Cases (%) |
---|---|
Cervical | 209 (3.8) |
Upper thoracic | 655 (12.0) |
Middle thoracic | 2448 (44.9) |
Lower thoracic | 1570 (28.8) |
EG | 380 (7.0) |
E = G | 98 (1.8) |
GE | 80 (1.5) |
Unknown | 11 (0.2) |
Total | 5451 |
Table 16 Approaches to tumor resection
Approaches | Cases (%) |
---|---|
Cervical | 176 (3.4) |
Right thoracic | 4492 (86.3) |
Left thoracic | 54 (1.0) |
Left thoracoabdominal | 82 (1.6) |
Abdominal | 187 (3.6) |
Transhiatal lower esophagectomy | 133 (2.6) |
Transhiatal thoracic esophagectomy | 64 (1.2) |
Sternotomy | 6 (0.1) |
Others | 7 (0.1) |
Unknown | 3 (0.1) |
Total | 5204 |
Table 17 Video-assisted surgery
Video-assisted surgery | Cases (%) |
---|---|
None | 2330 (44.6) |
Thoracoscopy | 1206 (23.2) |
Thoracoscopy + laparoscopy | 1281 (24.6) |
Thoracoscopy + laparoscopy + mediastinoscopy | 9 (0.2) |
Thoracoscopy + laparoscopy + other | |
Thoracoscopy + mediastinoscopy | 1 (0.0) |
Thoracoscopy + other | 4 (0.1) |
Laparoscopy | 265 (5.1) |
Laparoscopy + mediastinoscopy | 41 (0.8) |
Laparoscopy + mediastinoscopy + other | 1 (0.0) |
Mediastinoscopy | 49 (0.9) |
Laparoscopy + other | 1 (0.0) |
Others | 15 (0.3) |
Unknown | 1 (0.0) |
Total | 5204 |
Table 18 Fields of lymph-node dissection according to the location of the tumor
Field of lymphadenectomy | Cervical | Upper thoracic | Middle thoracic | Lower thoracic | Abdominal | E = G | GE | Unknown | Total |
---|---|---|---|---|---|---|---|---|---|
None | 8 (4.2) | 15 (2.5) | 46 (1.9) | 26 (1.7) | 4 (1.1) | 1 (1.1) | 4 (6.0) | 104 (2.0) | |
C | 47 (24.5) | 11 (1.8) | 33 (1.4) | 14 (0.9) | 105 (2.0) | ||||
C + UM | 21 (10.9) | 1 (0.2) | 2 (0.1) | 1 (0.3) | 25 (0.5) | ||||
C + UM + MLM | 4 (2.1) | 21 (3.4) | 50 (2.1) | 12 (0.8) | 1 (0.3) | 88 (1.7) | |||
C + UM + MLM + A | 83 (43.2) | 394 (64.6) | 1205 (64.6) | 577 (37.7) | 43 (12.0) | 6 (6.8) | 6 (9.0) | 1 (50.0) | 2315 (44.5) |
C + UM + A | 6 (3.1) | 10 (1.6) | 22 (0.9) | 10 (0.7) | 1 (0.3) | 49 (0.9) | |||
C + MLM | 1 (0.5) | 1 (0.2) | 2 (0.0) | ||||||
C + MLM + A | 1 (0.5) | 3 (0.5) | 15 (0.4) | 6 (0.4) | 3 (0.8) | 1 (1.1) | 29 (0.6) | ||
C + A | 4 (2.1) | 1 (0.2) | 1 (0.0) | 2 (0.1) | 8 (0.2) | ||||
UM | 2 (1.0) | 4 (0.7) | 11 (0.5) | 2 (0.1) | 19 (0.4) | ||||
UM + MLM | 3 (1.6) | 8 (1.3) | 40 (1.7) | 27 (1.8) | 4 (1.1) | 82 (1.6) | |||
UM + MLM + A | 5 (2.6) | 125 (20.5) | 847 (35.9) | 675 (44.1) | 115 (32.2) | 24 (27.3) | 3 (4.5) | 1 (50.0) | 1795 (34.5) |
UM + A | 5 (0.8) | 14 (0.6) | 9 (0.6) | 3 (0.8) | 1 (1.1) | 32 (0.6) | |||
MLM | 2 (0.3) | 11 (0.5) | 15 (1.0) | 3 (0.8) | 2 (2.3) | 1 (1.5) | 34 (0.7) | ||
MLM + A | 4 (0.7) | 48 (2.0) | 130 (8.5) | 139 (38.9) | 39 (44.3) | 33 (49.3) | 399 (7.7) | ||
A | 1 (0.5) | 5 (0.8) | 14 (0.6) | 24 (1.6) | 40 (11.2) | 14 (15.9) | 20 (29.9) | 118 (2.3) | |
Total | 192 | 610 | 2359 | 1529 | 357 | 88 | 67 | 2 | 5204 |
Table 19 Reconstruction route
Route | Cases (%) |
---|---|
None | 47 (0.9) |
Subcutaneous | 345 (6.6) |
Retrosternal | 2315 (44.5) |
Posterior mediastinal | 1920 (36.9) |
Intrathoracic | 465 (8.9) |
Cervical | 65 (1.2) |
Others | 41 (0.8) |
Unknown | 6 (0.1) |
Total | 5204 |
Table 20 Organs used for reconstruction
Organs | Cases (%) |
---|---|
None | 85 (1.6) |
Whole stomach | 105 (2.0) |
Gastric tube | 4425 (84.3) |
Jejunum | 272 (5.2) |
Free jejunum | 119 (2.3) |
Colon | 197 (3.8) |
Free colon | 10 (0.2) |
Others | 36 (0.7) |
Total organs | 5249 |
Total cases | 5119 |
Table 21 Histological classification
Histological classification | Cases (%) |
---|---|
Squamous cell carcinoma | 4324 (83.1) |
Squamous cell carcinoma | 751 (14.4) |
Well differentiated | 764 (14.7) |
Moderately differentiated | 2172 (41.7) |
Poorly differentiated | 637 (12.2) |
Adenocarcinoma | 347 (6.7) |
Barrett's carcinoma | 113 (2.2) |
Adenosquamous carcinoma | 29 (0.6) |
Mucoepidermoid carcinoma | 6 (0.1) |
Basaloid carcinoma | 82 (1.6) |
Neuroendocrine tumor | 2 (0.0) |
Neuroendocrine carcinoma | 25 (0.5) |
Undifferentiated carcinoma | 5 (0.1) |
Malignant melanoma | 19 (0.4) |
Carcinosarcoma | 37 (0.7) |
GIST | 7 (0.1) |
Adenoid cystic carcinoma | 1 (0.0) |
Sarcoma | 2 (0.0) |
Other carcinomas | 8 (0.2) |
Other tumors | 54 (1.0) |
Unknown | 143 (2.7) |
Total | 5204 |
Table 22 Depth of tumor invasion, pT (JES 10th)
Pathological depth of tumor invasion | Cases (%) |
---|---|
pTx | 42 (0.8) |
pT0 | 227 (4.4) |
pT1a | 645 (12.4) |
pT1b | 1475 (28.3) |
pT2 | 590 (11.3) |
pT3 | 1962 (37.7) |
pT4a | 141 (2.7) |
pT4b | 122 (2.3) |
Total | 5204 |
Table 23 Pathological grading of lymph-node metastasis, pN (JES 10th)
Lymph-node metastasis | Cases (%) |
---|---|
pN0 | 2568 (49.3) |
pN1 | 962 (18.5) |
pN2 | 966 (18.6) |
pN3 | 371 (7.1) |
pN4 | 321 (6.2) |
Unknown | 16 (0.3) |
Total | 5204 |
Table 24 Pathological findings of lymph-node metastasis, pN (UICC TNM 7th)
Lymph-node metastasis | Cases (%) |
---|---|
pN0 | 2611 (50.2) |
pN1 (1–2) | 1397 (26.8) |
pN2 (3–6) | 787 (15.1) |
pN3 (7-) | 373 (7.2) |
Unknown | 36 (0.7) |
Total | 5204 |
Table 25 Pathological findings of distant organ metastasis, pM (JES 10th)
Distant metastasis (M) | Cases (%) |
---|---|
MX | 110 (2.1) |
M0 | 4998 (96.0) |
M1 | 96 (1.8) |
Total | 5204 |
Table 26 Residual tumor
Residual tumor (R) | Cases (%) |
---|---|
RX | 95 (1.8) |
R0 | 4663 (89.6) |
R1 | 257 (4.9) |
R2 | 189 (3.6) |
Total | 5204 |
Figure 7 Survival of patients who underwent esophagectomy
Figure 8 Survival of patients who underwent esophagectomy according to the clinical stage (JES 10th)
Figure 9 Survival of patients who underwent esophagectomy according to the clinical stage (UICC TNM 7th)
Figure 10 Survival of patients who underwent esophagectomy according to the depth of tumor invasion, pT (JES 10th)
Figure 11 Survival of patients who underwent esophagectomy according to lymph node metastasis (JES 10th)
Figure 12 Survival of patients who underwent esophagectomy according to lymph node metastasis (UICC TNM 7th)
Figure 13 Survival of patients who underwent esophagectomy according to the pathological stage (JES 10th)
Figure 14 Survival of patients who underwent esophagectomy according to the pathological stage (UICC TNM 7th)
Figure 15 Survival of patients who underwent esophagectomy according to the residual tumor (R)
I. Clinical features of esophageal cancer patients treated in 2014
Institutions |
---|
Ageo Central General Hospital |
Aichi Cancer Center |
Aichi Medical University Hospital |
Aizawa Hospital |
Akita University Hospital |
Arao Municipal Hospital |
Asahi Rousai Hospital |
Asahikawa Medical University Hospital |
Cancer Institute Hospital of JFCR |
Chiba Cancer Center |
Chiba University Hospital |
Chiba-ken Saiseikai Narashino Hospital |
Dokkyo Medical University Hospital |
Dokkyo Medical University Saitama Medical Center |
Edogawa Hospital |
Ehime Prefectural Central Hospital |
Eijyu General Hospital |
Fuchu Hospital |
Fuji City General Hospital |
Fujinomiya City General Hospital |
Fujioka General Hospital |
Fujisaki Hospital |
Fujita Health University Hospital |
Fukaya Red Cross Hospital |
Fukui University Hospital |
Fukui-ken Saiseikai Hospital |
Fukuoka City Hospital |
Fukuoka Shin Mizumaki Hospital |
Fukuoka University Chikushi Hospital |
Fukuoka University Hospital |
Fukushima Medical University Hospital |
Fukuyama City Hospital |
Fussa Hospital |
Gifu Prefectural General Center |
Gifu University Hospital |
Gunma Prefectural Cancer Center |
Gunma Saiseikai Maebashi Hospital |
Gunma University Hospital |
Hachinohe City Hospital |
Hagi City Hospital |
Hakodate City Hospital |
Hakodate Goryokaku Hospital |
Hakodate National Hospital |
Hamamatsu University Hospital |
Hannan Chuo Hospital |
Hasuda Hospital |
Heartlife Hospital |
Higashiosaka City Medical Center |
Hiraka General Hospital |
Hiratsuka City Hospital |
Hirosaki University Hospital |
Hiroshima City Asa Hospital |
Hiroshima City Hospital |
Hiroshima Prefectural Hospital |
Hiroshima Red Cross Hospital & Atomic-Bomb Survivors Hospital |
Hiroshima University Hospital |
Hitachi General Hospital |
Hofu Institute of Gastroenterology |
Hokkaido University Hospital |
Hospital of the University of Occupational and Environmental Health, Japan |
Hyogo Cancer Center |
Hyogo Prefectural Amagasaki General Medical Center |
Hyogo Prefectural Nishinomiya Hospital |
Ibaraki Prefectural Central Hospital |
Iizuka Hospital |
Ikeda City Hospital |
Imari Arita Kyoritsu Hospital |
International University of Health and Welfare Atami Hospital |
International University of Health and Welfare Hospital |
International University of Health and Welfare Mita Hospital |
Isehara Kyodo Hospital |
Iseikai Hospital |
Ishikawa Prefectural Central Hospital |
Itami City Hospital |
Iwata City Hospital |
Iwate Medical University Hospital |
Iwate Prefectural Central Hospital |
Iwate Prefectural Chubu Hospital |
JA Hiroshima General Hospital |
JA Kouseiren Enshu Hospital |
JA Onomichi General Hospital |
Japanese Red Cross Ashikaga Hospital |
Japanese Red Cross Fukuoka Hospital |
Japanese Red Cross Ishinomaki Hospital |
Japanese Red Cross Kitami Hospital |
Japanese Red Cross Kyoto Daiichi Hospital |
Japanese Red Cross Maebashi Hospital |
Japanese Red Cross Medical Center |
Japanese Red Cross Musashino Hospital |
Japanese Red Cross Nagoya Daiichi Hospital |
Japanese Red Cross Nagoya Daini Hospital |
Japanese Red Cross Saitama Hospital |
Japanese Red Cross Tottori Hospital |
Japanese Red Cross Wakayama Medical Center |
Japanese Red Cross Yamaguchi Hospital |
JCHO Gunma Chuo Hospital |
JCHO Kyushu Hospital |
JCHO Osaka Hospital |
JCHO Saitama Medical Center |
Jichi Medical University Hospital |
Jichi Medical University Saitama Medical Center |
Juntendo University Hospital |
Juntendo University Nerima Hospital |
Juntendo University Shizuoka Hospital |
Juntendo University Urayasu Hospital |
Junwakai Memorial Hospital |
Kagawa Prefectural Central Hospital |
Kagawa Rosai Hospital |
Kagawa University Hospital |
Kagoshima City Hospital |
Kagoshima University Hospital |
Kakogawa Central City Hospital |
Kanagawa Cancer Center |
Kanagawa Prefectural Ashigarakami Hospital |
Kanazawa Medical University Hospital |
Kanazawa University Hospital |
Kansai Denryoku Hospital |
Kansai Medical University Hospital |
Kansai Medical University Medical Center |
Kansai Rosai Hospital |
Kashiwa Kousei General Hospital |
Kasugai Municipal Hospital |
Kawakita General Hospital |
Kawasaki Medical School Hospital |
Kawasaki Medical School Kawasaki Hospital |
Kawasaki Municipal Hospital |
Kawasaki Municipal Ida Hospital |
Kawasaki Saiwai Hospital |
Keio University Hospital |
Keiyukai Sapporo Hospital |
Kindai University Hospital |
Kindai University Nara Hospital |
Kinki Central Hospital |
Kiryu Kousei General Hospital |
Kishiwada City Hospital |
Kitaakita Municipal Hospital |
Kitaharima Medical Center |
Kitakyushu Municipal Medical Center |
Kitano Hospital |
Kitasato University Hospital |
Kobe City Medical Center General Hospital |
Kobe University Hospital |
Kochi Health Science Center |
Kochi University Hospital |
Kokura Memorial Hospital |
Kosei Hospital |
Kouseiren Takaoka Hospital |
Kumagai General Hospital |
Kumamoto University Hospital |
Kumamoto Regional Medical Center |
Kurashiki Central Hospital |
Kurume University Hospital |
Kyonan Medical Center Fujikawa Hospital |
Kyorin University Hospital |
Kyoto University Hospital |
Kyoto-Katsura Hospital |
Kyushu Central Hospital |
Kyushu University Hospital |
Machida Municipal Hospital |
Matsudo City General Hospital |
Matsushita Memorial Hospital |
Matsuyama Red Cross Hospital |
Mie University Hospital |
Minamiosaka Hospital |
Minoh City Hospital |
Mito Red Cross Hospital |
Mitsui Memorial Hospital |
Miyazaki University Hospital |
Moriguchi Keijinkai Hospital |
Nagahama City Hospital |
Nagahama Red Cross Hospital |
Nagano Municipal Hospital |
Nagaoka Chuo General Hospital |
Nagasaki University Hospital |
Nagoya City University Hospital |
Nagoya City West Medical Center |
Nagoya Tokushukai General Hospital |
Nagoya University Hospital |
Nanpuh Hospital |
Nara City Hospital |
Nara Medical University Hospital |
Nasu Red Cross Hospital |
National Cancer Center Hospital |
National Cancer Center Hospital East |
National Center for Global Health and Medicine |
National Defence Medical College Hospital |
Nerima Hikarigaoka Hospital |
New Tokyo Hospital |
NHO Beppu Medical Center |
NHO Chiba Medical Center |
NHO Iwakuni Clinical Center |
NHO Kure Medical Center |
NHO Kyoto Medical Center |
NHO Kyushu Cancer Center |
NHO Kyushu Medical Center |
NHO Matsumoto Medical Center |
NHO Mito Medical Center |
NHO Miyakonojo Medical Center |
NHO Nagasaki Medical Center |
NHO Nagoya Medical Center |
NHO Okayama Medical Center |
NHO Osaka Medical Center |
NHO Saga Hospital |
NHO Saitama Hospital |
NHO Sendai Medical Center |
NHO Shikoku Cancer Center |
NHO Takasaki General Medical Center |
NHO Tokyo Medical Center |
NHO Yokohama Medical Center |
Nihonkai General Hospital |
Niigata Cancer Center Hospital |
Niigata City General Hospital |
Niigata Prefectural Shibata Hospital |
Niigata University Medical & Dental Hospital |
Nikko Memorial Hospital |
Nippon Medical School Chiba Hokusou Hospital |
Nippon Medical School Hospital |
Nippon Medical School Musashi Kosugi Hospital |
Nippon Medical School Tama Nagayama Hospital |
Nishi Kobe Medical Center |
Northern Okinawa Medical Center |
NTT Medical Center Tokyo |
Numazu City Hospital |
Obihiro Kousei Hospital |
Ogaki Municipal Hospital |
Ogikubo Hospital |
Ogori Daiichi General Hospital |
Ohta Hospital |
Ohta Nishinouchi Hospital |
Oita Prefectural Hospital |
Oita Red Cross Hospital |
Oita University Hospital |
Okayama City Hospital |
Okayama Red Cross General Hospital |
Okayama Saiseikai General Hospital |
Okayama University Hospital |
Okitama Public General Hospital |
Onomichi Municipal Hospital |
Osaka City General Hospital |
Osaka City University Hospital |
Osaka General Medical Center |
Osaka International Cancer Institute |
Osaka Medical College Hospital |
Osaka Police Hospital |
Osaka Red Cross Hospital |
Osaka University Hospital |
Osaki City Hospital |
Otemae Hospital |
Otsu City Hospital |
Rinku General Medical Center |
Saga Prefectural Hospital Koseikan |
Saga University Hospital |
Saiseikai Fukuoka General Hospital |
Saiseikai Karatsu Hospital |
Saiseikai Kyoto Hospital |
Saiseikai Noe Hospital |
Saiseikai Utsunomiya Hospital |
Saiseikai Yamaguchi General Hospital |
Saiseikai Yokohama Tobu Hospital |
Saitama Medical University International Medical Center |
Saitama Medical University Saitama Medical Center |
Sakai City Medical Center |
Saku Central Hospital |
Sapporo Medical University Hospital |
Seikei-kai Chiba Medical Center |
Seirei Hamamatsu General Hospital |
Sendai City Hospital |
Sendai Kosei Hospital |
Shiga General Hospital |
Shiga University of Medical Science Hospital |
Shimane University Hospital |
Shin Takeo Hospital |
Shinko Hospital |
Shinshu University Hospital |
Shizuoka Cancer Center |
Shizuoka City Shizuoka Hospital |
Shizuoka General Hospital |
Showa University Hospital |
Southern Tohoku General Hospital |
St. Luke's International Hospital |
St. Marianna University School of Medicine Hospital |
St. Mary's Hospital |
Steel Memorial Yawata Hospital |
Suita Municipal Hospital |
Tachikawa Hospital |
Tagawa Municipal Hospital |
Takatsuki Red Cross Hospital |
Teikyo University Chiba Medical Center |
Teikyo University Hospital |
Teikyo University Hospital Mizonokuchi |
Teine Keijinkai Hospital |
Tenri Hospital |
The Hospital of Hyogo College of Medicine |
The Jikei University Daisan Hospital |
The Jikei University Hospital |
Tochigi Cancer Center |
Toda Central General Hospital |
Toho University Ohashi Medical Center |
Toho University Omori Medical Center |
Toho University Sakura Medical Center |
Tohoku University Hospital |
Tokai University Hachioji Hospital |
Tokai University Hospital |
Tokai University Tokyo Hospital |
Tokushima Red Cross Hospital |
Tokushima University Hospital |
Tokyo Dental College Ichikawa General Hospital |
Tokyo Medical and Dental University Hospital |
Tokyo Medical University Hachioji Medical Center |
Tokyo Medical University Hospital |
Tokyo Medical University Ibaraki Medical Center |
Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital |
Tokyo Metropolitan Tama Medical Center |
Tokyo University Hospital |
Tokyo Women's Medical University Hospital |
Tokyo Women's Medical University Medical Center East |
Tokyo Women's Medical University Yachiyo Medical Center |
Tonan Hospital |
Toshima Hospital |
Tottori Prefectural Central Hospital |
Tottori University Hospital |
Toyama Prefectural Central Hospital |
Toyama University Hospital |
Toyonaka Municipal Hospital |
Toyota Kosei Hospital |
Toyota Memorial Hospital |
Tsuchiura Kyodo Hospital |
Tsukuba University Hospital |
Tsuruoka Municipal Shonal Hospital |
University Hospital, Kyoto Prefectural University of Medicine |
University of the Ryukyus Hospital |
Wakayama Medical University Hospital |
Yamagata Prefectural Central Hospital |
Yamagata University Hospital |
Yamaguchi University Hospital |
Yamanashi Prefectural Central Hospital |
Yamanashi University Hospital |
Yao Municipal Hospital |
Yokkaichi Hospital |
Yokohama City Municipal Hospital |
Yokohama City University Hospital |
Yokohama City University Medical Center |
Yonezawa City Hospital |
Yuai Memorial Hospital |
II. Results in patients treated with chemotherapy and/or radiotherapy in 2014
III. Results in patients who underwent esophagectomy in 2014
Cause of death | Cases (%) |
---|---|
Death due to recurrence | 1806 (62.0) |
Death due to other cancer | 231 (7.9) |
Death due to other disease (with recurrence) | 65 (2.2) |
Death due to other disease (without recurrence) | 402 (13.8) |
Death due to other disease (recurrence unknown) | 12 (0.4) |
Operative death* | 39 (1.3) |
Postoperative hospital death** | 65 (2.2) |
Unknown | 291 (10.0) |
Total of death cases | 2911 |
Follow-up period (months) | |
---|---|
Median (min.–max.) | 55.29 (0.07–78.78) |