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13.01.2022 | Original Paper

The Relationship Between Harmful Alcohol Use and Antiretroviral Non-adherence in People Accessing HIV Treatment in Cape Town, South Africa: An Event-Level Analysis

verfasst von: Alexandra L. Rose, Jennifer M. Belus, Tianzhou Ma, Jasper S. Lee, Christine Wan, Andres De Los Reyes, John A. Joska, Lena S. Andersen, Bronwyn Myers, Jessica F. Magidson

Erschienen in: AIDS and Behavior | Ausgabe 6/2022

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Abstract

Harmful alcohol consumption can significantly compromise adherence to antiretroviral therapy (ART). Prior research has identified aggregate relationships between alcohol use and ART non-adherence, largely relying on concurrent assessment of these domains. There is relatively limited evidence on more nuanced day-level associations between alcohol use and ART non-adherence, despite potentially important clinical implications. We recruited adults with HIV treatment adherence challenges and harmful alcohol use (n = 53) from HIV care in South Africa. We examined relationships between alcohol use and same and next day ART adherence, accounting for the role of weekends/holidays and participant demographics, including gender. Results demonstrated that ART adherence was significantly worse on weekend/holiday days. Next day adherence was significantly worse in the context of weekend alcohol use and among men. These results suggest the importance of tailoring intervention strategies to support ART adherence during weekend drinking and for men engaged in heavy episodic drinking.

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Titel: The Relationship Between Harmful Alcohol Use and Antiretroviral Non-adherence in People Accessing HIV Treatment in Cape Town, South Africa: An Event-Level Analysis
verfasst von: Alexandra L. Rose
Jennifer M. Belus
Tianzhou Ma
Jasper S. Lee
Christine Wan
Andres De Los Reyes
John A. Joska
Lena S. Andersen
Bronwyn Myers
Jessica F. Magidson
Publikationsdatum: 13.01.2022
Verlag: Springer US
Erschienen in: AIDS and Behavior / Ausgabe 6/2022
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-021-03552-x

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