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Heart Failure Reviews

Erschienen in:

14.06.2019

Re-evaluating the causes and consequences of non-resolving inflammation in chronic cardiovascular disease

verfasst von: Amanda B. Pullen, Jeevan Kumar Jadapalli, Boutayna Rhourri-Frih, Ganesh V. Halade

Erschienen in: Heart Failure Reviews | Ausgabe 2/2020

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Abstract

Cardiac injuries, like heart attacks, drive the secondary pathology with advanced heart failure. In this process, non-resolving inflammation is a prime component of accelerated cardiovascular disease and subsequent fatal events associated with imbalanced diet, physical inactivity, disrupted circadian rhythms, neuro-hormonal stress, and poly- or co-medication. Laboratory rodents have established that splenic leukocyte–directed resolution mechanisms are essential for cardiac repair after injury. Here, we discuss the impact of three lifestyle-related factors that are prime causes of derailed cardiac healing, putative non-resolving inflammation-resolution mechanisms in cardiovascular diseases, and progressive heart failure after cardiac injury. The presented review resurfaces the lifestyle-related risks and future research directions required to understand the molecular and cellular mechanisms between the causes of cardiovascular disease and their related consequences of non-resolving inflammation.

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Titel: Re-evaluating the causes and consequences of non-resolving inflammation in chronic cardiovascular disease
verfasst von: Amanda B. Pullen
Jeevan Kumar Jadapalli
Boutayna Rhourri-Frih
Ganesh V. Halade
Publikationsdatum: 14.06.2019
Verlag: Springer US
Erschienen in: Heart Failure Reviews / Ausgabe 2/2020
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI: https://doi.org/10.1007/s10741-019-09817-x

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Re-evaluating the causes and consequences of non-resolving inflammation in chronic cardiovascular disease

Abstract

Neu im Fachgebiet Kardiologie

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

Update Kardiologie

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Abstract

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