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Erschienen in: Quality of Life Research 6/2018

15.02.2018

Hysterectomy and perceived physical function in middle-aged Australian women: a 20-year population-based prospective cohort study

verfasst von: Louise F. Wilson, Nirmala Pandeya, Julie Byles, Gita D. Mishra

Erschienen in: Quality of Life Research | Ausgabe 6/2018

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Abstract

Purpose

Hysterectomy is one of the most common gynaecological procedures worldwide. Changes in endocrine function may impact age-associated decline in physical function and these changes may be accelerated by hysterectomy. The aim of this study was to investigate associations between hysterectomy status and self-reported physical function limitations.

Methods

Our study sample (n = 8624) came from the mid-cohort (born 1945–1950) of the Australian Longitudinal Study on Women’s Health (ALSWH). Self-report of physical function was measured by the Physical Functioning (PF) subscale of the Medical Outcomes Study Short Form Health Survey (SF-36) over seven surveys (1998–2016), categorised into substantial, moderate and minimal PF-limitations. The associations between hysterectomy status and de novo substantial or moderate PF-limitations versus minimal PF-limitations were investigated using log-multinomial regression.

Results

By Survey 8 (2016), 20% of the study sample had a hysterectomy with ovarian conservation (hysterectomy only) and 9% had a hysterectomy and both ovaries removed (hysterectomy-bilateral oophorectomy). Women with a hysterectomy only had a small increase in risk of substantial PF-limitations (versus minimal PF-limitations) compared to women with no hysterectomy (relative risk [RR]: 1.13; 95% confidence interval [95% CI] 1.00–1.27); the point estimate was stronger for women with a hysterectomy-bilateral oophorectomy (RR: 1.26; 95% CI 1.09–1.46). In a supplementary analysis, the increased risk of substantial PF-limitations was seen only in women who had surgery before the age of 45 years.

Conclusions

Compared to women with no hysterectomy, women with hysterectomy-bilateral oophorectomy were at increased risk of substantial PF-limitations versus minimal PF-limitations over 18 years of follow-up.
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Literatur
1.
Zurück zum Zitat Maltais, M. L., Desroches, J., & Dionne, I. J. (2009). Changes in muscle mass and strength after menopause. Journal of Musculoskelet Neuronal Interact, 9(4), 186–197. Maltais, M. L., Desroches, J., & Dionne, I. J. (2009). Changes in muscle mass and strength after menopause. Journal of Musculoskelet Neuronal Interact, 9(4), 186–197.
2.
Zurück zum Zitat Murray, E. T., Hardy, R., Strand, B. H., Cooper, R., Guralnik, J. M., & Kuh, D. (2011). Gender and life course occupational social class differences in trajectories of functional limitations in midlife: findings from the 1946 British birth cohort. Journal of Gerontology. Series A, Biological Sciences and Medical Sciences, 66(12), 1350–1359. https://doi.org/10.1093/gerona/glr139.CrossRef Murray, E. T., Hardy, R., Strand, B. H., Cooper, R., Guralnik, J. M., & Kuh, D. (2011). Gender and life course occupational social class differences in trajectories of functional limitations in midlife: findings from the 1946 British birth cohort. Journal of Gerontology. Series A, Biological Sciences and Medical Sciences, 66(12), 1350–1359. https://​doi.​org/​10.​1093/​gerona/​glr139.CrossRef
3.
Zurück zum Zitat Holmes, J., Powell-Griner, E., Lethbridge-Cejku, M., & Heyman, K. (2009). Aging differently: Physical limitations among adults aged 50 years and over: United States, 2001–2007. NCHS Data Brief(20), 1–8. Holmes, J., Powell-Griner, E., Lethbridge-Cejku, M., & Heyman, K. (2009). Aging differently: Physical limitations among adults aged 50 years and over: United States, 2001–2007. NCHS Data Brief(20), 1–8.
4.
Zurück zum Zitat Copeland, J. L., Chu, S. Y., & Tremblay, M. S. (2004). Aging, physical activity, and hormones in women—A review. Journal of Aging and Physical Activity, 12(1), 101–116.CrossRefPubMed Copeland, J. L., Chu, S. Y., & Tremblay, M. S. (2004). Aging, physical activity, and hormones in women—A review. Journal of Aging and Physical Activity, 12(1), 101–116.CrossRefPubMed
6.
Zurück zum Zitat Redburn, J. C., & Murphy, M. F. (2001). Hysterectomy prevalence and adjusted cervical and uterine cancer rates in England and Wales. BJOG, 108(4), 388–395.PubMed Redburn, J. C., & Murphy, M. F. (2001). Hysterectomy prevalence and adjusted cervical and uterine cancer rates in England and Wales. BJOG, 108(4), 388–395.PubMed
10.
Zurück zum Zitat Nahas, E., Pontes, A., Traiman, P., NahasNeto, J., Dalben, I., & De Luca, L. (2003). Inhibin B and ovarian function after total abdominal hysterectomy in women of reproductive age. Gynecological Endocrinology, 17(2), 125–131.CrossRefPubMed Nahas, E., Pontes, A., Traiman, P., NahasNeto, J., Dalben, I., & De Luca, L. (2003). Inhibin B and ovarian function after total abdominal hysterectomy in women of reproductive age. Gynecological Endocrinology, 17(2), 125–131.CrossRefPubMed
11.
Zurück zum Zitat Atay, V., Ceyhan, T., Baser, I., Gungor, S., Goktolga, U., & Muhcu, M. (2007). Hysterectomy with preservation of both ovaries does not result in premature ovarian failure. Journal of International Medical Research, 35(3), 416–421.CrossRefPubMed Atay, V., Ceyhan, T., Baser, I., Gungor, S., Goktolga, U., & Muhcu, M. (2007). Hysterectomy with preservation of both ovaries does not result in premature ovarian failure. Journal of International Medical Research, 35(3), 416–421.CrossRefPubMed
12.
Zurück zum Zitat Lee, D. Y., Park, H. J., Kim, B. G., Bae, D. S., Yoon, B. K., & Choi, D. (2010). Change in the ovarian environment after hysterectomy as assessed by ovarian arterial blood flow indices and serum anti-Mullerian hormone levels. European Journal of Obstetrics & Gynecology and Reproductive Biology, 151(1), 82–85. https://doi.org/10.1016/j.ejogrb.2010.02.037.CrossRef Lee, D. Y., Park, H. J., Kim, B. G., Bae, D. S., Yoon, B. K., & Choi, D. (2010). Change in the ovarian environment after hysterectomy as assessed by ovarian arterial blood flow indices and serum anti-Mullerian hormone levels. European Journal of Obstetrics & Gynecology and Reproductive Biology, 151(1), 82–85. https://​doi.​org/​10.​1016/​j.​ejogrb.​2010.​02.​037.CrossRef
13.
Zurück zum Zitat El Khoudary, S. R., McClure, C. K., VoPham, T., Karvonen-Gutierrez, C. A., Sternfeld, B., Cauley, J. A., Khalil, N., & Sutton-Tyrrell, K. (2014). Longitudinal assessment of the menopausal transition, endogenous sex hormones, and perception of physical functioning: The Study of Women’s Health Across the Nation. Journal of Gerontology: Series A Biological Sciences and Medical Sciences, 69(8), 1011–1017. https://doi.org/10.1093/gerona/glt285.CrossRef El Khoudary, S. R., McClure, C. K., VoPham, T., Karvonen-Gutierrez, C. A., Sternfeld, B., Cauley, J. A., Khalil, N., & Sutton-Tyrrell, K. (2014). Longitudinal assessment of the menopausal transition, endogenous sex hormones, and perception of physical functioning: The Study of Women’s Health Across the Nation. Journal of Gerontology: Series A Biological Sciences and Medical Sciences, 69(8), 1011–1017. https://​doi.​org/​10.​1093/​gerona/​glt285.CrossRef
14.
Zurück zum Zitat Sowers, M., Pope, S., Welch, G., Sternfeld, B., & Albrecht, G. (2001). The association of menopause and physical functioning in women at midlife. Journal of American Geriatrics Society, 49(11), 1485–1492.CrossRef Sowers, M., Pope, S., Welch, G., Sternfeld, B., & Albrecht, G. (2001). The association of menopause and physical functioning in women at midlife. Journal of American Geriatrics Society, 49(11), 1485–1492.CrossRef
18.
19.
21.
Zurück zum Zitat Ware, J. E., Snow, K. K., Kosinski, M., & Gandek, B. (1993). SF-36 health survey manual and interpretation guide. Boston, MA: The Health Institute, New England Medical Center. Ware, J. E., Snow, K. K., Kosinski, M., & Gandek, B. (1993). SF-36 health survey manual and interpretation guide. Boston, MA: The Health Institute, New England Medical Center.
22.
Zurück zum Zitat Rose, M. S., Koshman, M. L., Spreng, S., & Sheldon, R. (1999). Statistical issues encountered in the comparison of health-related quality of life in diseased patients to published general population norms: problems and solutions. Journal of Clinical Epidemiology, 52(5), 405–412.CrossRefPubMed Rose, M. S., Koshman, M. L., Spreng, S., & Sheldon, R. (1999). Statistical issues encountered in the comparison of health-related quality of life in diseased patients to published general population norms: problems and solutions. Journal of Clinical Epidemiology, 52(5), 405–412.CrossRefPubMed
23.
Zurück zum Zitat World Health Organisation Consultation on Obesity. (1999). Obesity: Preventing and managing the global epidemic: Report of a WHO Consultation. Geneva: WHO. World Health Organisation Consultation on Obesity. (1999). Obesity: Preventing and managing the global epidemic: Report of a WHO Consultation. Geneva: WHO.
24.
Zurück zum Zitat Commonwealth Department of Health and Aged Care. (1999). An active way to better health: national physical activity guidelines for adults. Canberra: AGPS. Commonwealth Department of Health and Aged Care. (1999). An active way to better health: national physical activity guidelines for adults. Canberra: AGPS.
25.
Zurück zum Zitat Welch, C., Bartlett, J., & Petersen, I. (2014). Application of multiple imputation using the two-fold fully conditional specification algorithm in longitudinal clinical data. Stata J, 14(2), 418–431.PubMedPubMedCentral Welch, C., Bartlett, J., & Petersen, I. (2014). Application of multiple imputation using the two-fold fully conditional specification algorithm in longitudinal clinical data. Stata J, 14(2), 418–431.PubMedPubMedCentral
27.
Zurück zum Zitat StataCorp. (2011). Stata statistical software: Release 12. College Station: StataCorp LP. StataCorp. (2011). Stata statistical software: Release 12. College Station: StataCorp LP.
28.
Zurück zum Zitat Colditz, G. A., Stampfer, M. J., Willett, W. C., Stason, W. B., Rosner, B., Hennekens, C. H., & Speizer, F. E. (1987). Reproducibility and validity of self-reported menopausal status in a prospective cohort study. American Journal of Epidemiology, 126(2), 319–325.CrossRefPubMed Colditz, G. A., Stampfer, M. J., Willett, W. C., Stason, W. B., Rosner, B., Hennekens, C. H., & Speizer, F. E. (1987). Reproducibility and validity of self-reported menopausal status in a prospective cohort study. American Journal of Epidemiology, 126(2), 319–325.CrossRefPubMed
29.
Zurück zum Zitat Green, A., Purdie, D., Green, L., Dick, M. L., Bain, C., & Siskind, V. (1997). Validity of self-reported hysterectomy and tubal sterilisation. The Survey of Women’s Health Study Group. Australian and New Zealand Journal of Public Health, 21(3), 337–340.CrossRefPubMed Green, A., Purdie, D., Green, L., Dick, M. L., Bain, C., & Siskind, V. (1997). Validity of self-reported hysterectomy and tubal sterilisation. The Survey of Women’s Health Study Group. Australian and New Zealand Journal of Public Health, 21(3), 337–340.CrossRefPubMed
Metadaten
Titel
Hysterectomy and perceived physical function in middle-aged Australian women: a 20-year population-based prospective cohort study
verfasst von
Louise F. Wilson
Nirmala Pandeya
Julie Byles
Gita D. Mishra
Publikationsdatum
15.02.2018
Verlag
Springer International Publishing
Erschienen in
Quality of Life Research / Ausgabe 6/2018
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-1812-9

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