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Erschienen in:
04.03.2016 | Therapy in Practice
Severe Hyponatremia and Immune Nephritis Following an Initial Infusion of Nivolumab
Erschienen in: Targeted Oncology | Ausgabe 4/2016
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Anti-programmed cell death-1 (PD-1) antibodies pembrolizumab and nivolumab are becoming increasingly important in the treatment of melanoma and non-small cell lung cancer. These agents are known to induce many immune-related adverse events, but rapid-onset nephritis and immune-related hyponatremia have not been described to date. We describe the case of an adult patient who developed severe hyponatremia and rapid-onset nephritis following the first infusion of nivolumab for metastatic melanoma.
