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Erschienen in:
01.07.2015 | Original Article
Comparison of myocardial F-18 FDG uptake between overnight and non-overnight fasting in non-diabetic healthy subjects
Erschienen in: Japanese Journal of Radiology | Ausgabe 7/2015
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Purpose
To evaluate whether an overnight or non-overnight fast for suppressing
physiological FDG uptake by the myocardium is better in non-diabetic healthy subjects before F-18 FDG PET/CT studies.
Materials and methods
One hundred two subjects who underwent whole-body F-18 FDG PET/CT for routine health checkups were retrospectively reviewed. For quantitative assessment, a region of interest was drawn around the entire left ventricle visible in the axial view containing the highest visual uptake in order to measure the maximum standardized uptake value (SUVmax). FDG uptake in the myocardium was visually graded as follows: grade 0 = minimal, 1 = mostly minimal or mild, 2 = mostly intense or moderate, and 3 = homogeneously intense. Adequate suppression of myocardial uptake was quantitatively defined as a SUVmax ≤5.0 and grade 0 by visual assessment.
Results
With regard to the SUVmax, myocardial uptake was not different between the overnight and the non-overnight fasting subjects (P = 0.753). In subjects who had adequate suppression of myocardial uptake, no significant difference was observed between the overnight and non-overnight fasting subjects either in terms of visual or quantitative assessment (P = 0.539 and P = 0.678, respectively).
Conclusion
Both overnight and non-overnight fasts are not adequate for suppressing the physiological uptake of FDG by the myocardium.