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Erschienen in: Archives of Osteoporosis 1/2021

01.12.2021 | Original Article

Osteoporosis treatment rate following hip fracture in a community hospital

verfasst von: Aliya A. Khan, Hajar AbuAlrob, Farhan Tariq, Madiha Tauqir, Paul Zalzal, Iman M’Hiri, Moin Khan, Mark Ginty, Brad Weening

Erschienen in: Archives of Osteoporosis | Ausgabe 1/2021

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Abstract

Summary

Treatment rates for osteoporosis after a major osteoporotic fracture are unacceptably low. We evaluate the effectiveness of an ortho-geriatric team (OGT) in initiating pharmacologic therapy for osteoporosis post-hip fracture. The OGT was able to achieve a higher treatment rate for patients post-hip fracture in comparison to usual care provided by the primary care hospitalist. Potential reasons for delaying or not proceeding with drug therapy include patient concern regarding potential rare side effects of antiresorptive therapy including osteonecrosis of the jaw and atypical femoral fracture. These events however are rare, and in this study, only 3% of hip fractures were atypical femoral fractures.

Introduction

Currently, a significant care gap for osteoporosis therapy exists post-hip fracture despite advances in pharmacologic therapy. We evaluate the effectiveness of the OGT at the Oakville Trafalgar Memorial Hospital (OTMH), Ontario, Canada, in reducing the care gap and initiating pharmacologic therapy in hip fracture patients prior to hospital discharge. We also evaluated the incidence of atypical femoral fracture (AFF) separately.

Methods

A retrospective chart review of patients 59 years and older with a hip fracture admitted to OTMH from January 1, 2016, to February 1, 2017, was conducted. The primary outcome was the proportion of hip fracture patients discharged from the hospital with appropriate treatment for their underlying osteoporosis. A sub-analysis was completed reporting the incidence of AFF among older adults.

Results

A total of 197 patients with a hip fracture were identified, 134/197 (68%) patients were seen by the OGT, 98/134 (73%) of these patients were started on pharmacologic therapy prior to discharge, and 120/134 (89%) of patients seen by the OGT were on treatment within 3 months of discharge following assessment in the complex osteoporosis clinic. Sixty-three patients of the 197 (63/197) (32%) of the hip fracture patients were seen by a hospitalist, and treatment rates prior to discharge were 5%. Only 6/197 patients had experienced an AFF during the study period, and all patients with an atypical femoral fracture had been on long-term bisphosphonate therapy. All of the patients with an AFF had thigh or groin pain for several weeks to months prior to the development of the atypical femoral fracture, providing an opportunity to stop therapy and possibly prevent the development of a complete AFF.

Conclusion

The OGT was able to initiate anti-osteoporosis therapy in significantly more patients in comparison to usual care, and higher treatment rates are possible with an OGT.
Literatur
1.
Zurück zum Zitat Khan A, Fortier M, Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Graves L, Guthrie B, Johnston S, Rowe T, Sodhi N, Wilks P, Wolfman W (2014) Menopause and osteoporosis working group. Osteoporosis in menopause. J Obstet Gynaecol Can 36(9):839–840PubMedCrossRef Khan A, Fortier M, Reid R, Abramson BL, Blake J, Desindes S, Dodin S, Graves L, Guthrie B, Johnston S, Rowe T, Sodhi N, Wilks P, Wolfman W (2014) Menopause and osteoporosis working group. Osteoporosis in menopause. J Obstet Gynaecol Can 36(9):839–840PubMedCrossRef
2.
Zurück zum Zitat Jiang HX, Majumdar SR, Dick DA, Moreau M, Raso J, Otto DD, Johnston DW (2005) Development and initial validation of a risk score for predicting in-hospital and 1-year mortality in patients with hip fractures. J Bone Miner Res 20(3):494–500PubMedCrossRef Jiang HX, Majumdar SR, Dick DA, Moreau M, Raso J, Otto DD, Johnston DW (2005) Development and initial validation of a risk score for predicting in-hospital and 1-year mortality in patients with hip fractures. J Bone Miner Res 20(3):494–500PubMedCrossRef
3.
Zurück zum Zitat Panula J, Pihlajamäki H, Mattila VM, Jaatinen P, Vahlberg T, Aarnio P, Kivelä SL (2011) Mortality and cause of death in hip fracture patients aged 65 or older: a population-based study. BMC Musculoskelet Disord 12:105PubMedPubMedCentralCrossRef Panula J, Pihlajamäki H, Mattila VM, Jaatinen P, Vahlberg T, Aarnio P, Kivelä SL (2011) Mortality and cause of death in hip fracture patients aged 65 or older: a population-based study. BMC Musculoskelet Disord 12:105PubMedPubMedCentralCrossRef
4.
Zurück zum Zitat Johnell O, Kanis JA (2004) An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 15(11):897–902PubMedCrossRef Johnell O, Kanis JA (2004) An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 15(11):897–902PubMedCrossRef
6.
Zurück zum Zitat Vestergaard P, Rejnmark L, Mosekilde L (2007) Increased mortality in patients with a hip fracture-effect of pre-morbid conditions and post-fracture complications. Osteoporos Int 18(12):1583–1593PubMedCrossRef Vestergaard P, Rejnmark L, Mosekilde L (2007) Increased mortality in patients with a hip fracture-effect of pre-morbid conditions and post-fracture complications. Osteoporos Int 18(12):1583–1593PubMedCrossRef
7.
Zurück zum Zitat Valizadeh M, Mazloomzadeh S, Golmohammadi S, Larijani B (2012) Mortality after low trauma hip fracture: a prospective cohort study. BMC Musculoskelet Disord 13:143PubMedPubMedCentralCrossRef Valizadeh M, Mazloomzadeh S, Golmohammadi S, Larijani B (2012) Mortality after low trauma hip fracture: a prospective cohort study. BMC Musculoskelet Disord 13:143PubMedPubMedCentralCrossRef
8.
Zurück zum Zitat Leibson CL, Tosteson AN, Gabriel SE, Ransom JE, Melton LJ (2002) Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study. J Am Geriatr Soc 50(10):1644–1650PubMedCrossRef Leibson CL, Tosteson AN, Gabriel SE, Ransom JE, Melton LJ (2002) Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study. J Am Geriatr Soc 50(10):1644–1650PubMedCrossRef
9.
Zurück zum Zitat De Joode SGCJ, Kalmet PHS, Fiddelers AAA, Poeze M, Blokhuis TJ (2019) Long-term functional outcome after a low-energy hip fracture in elderly patients. J Orthop Traumatol 20(1):20PubMedPubMedCentralCrossRef De Joode SGCJ, Kalmet PHS, Fiddelers AAA, Poeze M, Blokhuis TJ (2019) Long-term functional outcome after a low-energy hip fracture in elderly patients. J Orthop Traumatol 20(1):20PubMedPubMedCentralCrossRef
10.
Zurück zum Zitat Salpakoski A, Törmäkangas T, Edgren J, Sihvonen S, Pekkonen M, Heinonen A, Pesola M, Kallinen M, Rantanen T, Sipilä S (2014) Walking recovery after a hip fracture: a prospective follow-up study among community-dwelling over 60-year old men and women. Biomed Res Int 2014:289549PubMedPubMedCentralCrossRef Salpakoski A, Törmäkangas T, Edgren J, Sihvonen S, Pekkonen M, Heinonen A, Pesola M, Kallinen M, Rantanen T, Sipilä S (2014) Walking recovery after a hip fracture: a prospective follow-up study among community-dwelling over 60-year old men and women. Biomed Res Int 2014:289549PubMedPubMedCentralCrossRef
11.
Zurück zum Zitat Adachi JD, Adami S, Gehlbach S, Anderson FA Jr, Boonen S, Chapurlat RD, Compston JE, Cooper C, Delmas P, Díez-Pérez A, Greenspan SL, Hooven FH, LaCroix AZ, Lindsay R, Netelenbos JC, Wu O, Pfeilschifter J, Roux C, Saag KG, Sambrook PN, Silverman S, Siris ES, Nika G (2010) Watts NB; GLOW Investigators. Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women. Mayo Clin Proc 85(9):806–813PubMedPubMedCentralCrossRef Adachi JD, Adami S, Gehlbach S, Anderson FA Jr, Boonen S, Chapurlat RD, Compston JE, Cooper C, Delmas P, Díez-Pérez A, Greenspan SL, Hooven FH, LaCroix AZ, Lindsay R, Netelenbos JC, Wu O, Pfeilschifter J, Roux C, Saag KG, Sambrook PN, Silverman S, Siris ES, Nika G (2010) Watts NB; GLOW Investigators. Impact of prevalent fractures on quality of life: baseline results from the global longitudinal study of osteoporosis in women. Mayo Clin Proc 85(9):806–813PubMedPubMedCentralCrossRef
12.
Zurück zum Zitat Cranney AB, Coyle D, Hopman WM, Hum V, Power B, Tugwell PS (2005 Dec) Prospective evaluation of preferences and quality of life in women with hip fractures. J Rheumatol 32(12):2393–2399PubMed Cranney AB, Coyle D, Hopman WM, Hum V, Power B, Tugwell PS (2005 Dec) Prospective evaluation of preferences and quality of life in women with hip fractures. J Rheumatol 32(12):2393–2399PubMed
13.
Zurück zum Zitat Tidermark J, Bergström G (2007) Responsiveness of the EuroQol (EQ-5D) and the Nottingham Health Profile (NHP) in elderly patients with femoral neck fractures. Qual Life Res 16(2):321–330PubMedCrossRef Tidermark J, Bergström G (2007) Responsiveness of the EuroQol (EQ-5D) and the Nottingham Health Profile (NHP) in elderly patients with femoral neck fractures. Qual Life Res 16(2):321–330PubMedCrossRef
14.
Zurück zum Zitat Hallberg I, Rosenqvist AM, Kartous L, Lofman O, Wahlstrom O, Toss G (2004) Health-related quality of life after osteoporotic fractures. Osteoporos Int 15(10):834–841PubMedCrossRef Hallberg I, Rosenqvist AM, Kartous L, Lofman O, Wahlstrom O, Toss G (2004) Health-related quality of life after osteoporotic fractures. Osteoporos Int 15(10):834–841PubMedCrossRef
15.
Zurück zum Zitat Peterson MG, Allegrante JP, Cornell CN, MacKenzie CR, Robbins L, Horton R, Ganz SB, Augurt A (2002) Measuring recovery after a hip fracture using the SF-36 and Cummings scales. Osteoporos Int 13(4):296–302PubMedCrossRef Peterson MG, Allegrante JP, Cornell CN, MacKenzie CR, Robbins L, Horton R, Ganz SB, Augurt A (2002) Measuring recovery after a hip fracture using the SF-36 and Cummings scales. Osteoporos Int 13(4):296–302PubMedCrossRef
16.
Zurück zum Zitat Haentjens P, Magaziner J, Colón-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, Boonen S (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 16;152(6):380-90. Haentjens P, Magaziner J, Colón-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, Boonen S (2010) Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med 16;152(6):380-90.
17.
Zurück zum Zitat Abrahamsen B, van Staa T, Ariely R, Olson M, Cooper C (2009) Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int 20(10):1633–1650PubMedCrossRef Abrahamsen B, van Staa T, Ariely R, Olson M, Cooper C (2009) Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int 20(10):1633–1650PubMedCrossRef
18.
Zurück zum Zitat Jacobsen SJ, Goldberg J, Miles TP, Brody JA, Stiers W, Rimm AA (1992) Race and sex differences in mortality following fracture of the hip. Am J Public Health 82(8):1147–1150PubMedPubMedCentralCrossRef Jacobsen SJ, Goldberg J, Miles TP, Brody JA, Stiers W, Rimm AA (1992) Race and sex differences in mortality following fracture of the hip. Am J Public Health 82(8):1147–1150PubMedPubMedCentralCrossRef
19.
Zurück zum Zitat Singer A, Exuzides A, Spangler L, O’Malley C, Colby C, Johnston K, Agodoa I, Baker J, Kagan R (2015) Burden of illness for osteoporotic fractures compared with other serious diseases among postmenopausal women in the United States. Mayo Clin Proc 90(1):53–62PubMedCrossRef Singer A, Exuzides A, Spangler L, O’Malley C, Colby C, Johnston K, Agodoa I, Baker J, Kagan R (2015) Burden of illness for osteoporotic fractures compared with other serious diseases among postmenopausal women in the United States. Mayo Clin Proc 90(1):53–62PubMedCrossRef
20.
Zurück zum Zitat Kannus P, Parkkari J, Sievanen H, Heinonen A, Vuori I, Jarvinen M (1998) Epidemiology of hip fracture. Bone 18:57S–63SCrossRef Kannus P, Parkkari J, Sievanen H, Heinonen A, Vuori I, Jarvinen M (1998) Epidemiology of hip fracture. Bone 18:57S–63SCrossRef
21.
Zurück zum Zitat Wade SW, Strader C, Fitzpatrick LA, Anthony MS (2012) Sex- and age-specific incidence of non-traumatic fractures in selected industrialized countries. Arch Osteoporos 7:219–227PubMedCrossRef Wade SW, Strader C, Fitzpatrick LA, Anthony MS (2012) Sex- and age-specific incidence of non-traumatic fractures in selected industrialized countries. Arch Osteoporos 7:219–227PubMedCrossRef
22.
Zurück zum Zitat Johnell O, Kanis J, Gullber G (2001) Mortality, morbidity and assessment of fracture risk in male osteoporosis. Calcif Tissue Int 69:182–184PubMedCrossRef Johnell O, Kanis J, Gullber G (2001) Mortality, morbidity and assessment of fracture risk in male osteoporosis. Calcif Tissue Int 69:182–184PubMedCrossRef
23.
Zurück zum Zitat Juby AG, De Geus-Wenceslau CM (2002) Evaluation of osteoporosis treatment in seniors after hip fracture. Osteoporos Int 13(3):205–210PubMedCrossRef Juby AG, De Geus-Wenceslau CM (2002) Evaluation of osteoporosis treatment in seniors after hip fracture. Osteoporos Int 13(3):205–210PubMedCrossRef
24.
Zurück zum Zitat Khosla S, Cauley JA, Compston J, Kiel DP, Rosen C, Saag KG, Shane E (2017) Addressing the crisis in the treatment of osteoporosis: a path forward. J Bone Miner Res 32(3):424–430PubMedCrossRef Khosla S, Cauley JA, Compston J, Kiel DP, Rosen C, Saag KG, Shane E (2017) Addressing the crisis in the treatment of osteoporosis: a path forward. J Bone Miner Res 32(3):424–430PubMedCrossRef
25.
Zurück zum Zitat Lewiecki EM (2016) Hip fractures and declining DXA testing: at a breaking point? J Bone Miner Res 31(Suppl 1) Lewiecki EM (2016) Hip fractures and declining DXA testing: at a breaking point? J Bone Miner Res 31(Suppl 1)
26.
Zurück zum Zitat Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041):1535–1541PubMedCrossRef Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348(9041):1535–1541PubMedCrossRef
27.
Zurück zum Zitat Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, Palermo L, Prineas R, Rubin SM, Scott JC, Vogt T, Wallace R, Yates AJ, LaCroix AZ (1998) Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 280(24):2077–2082PubMedCrossRef Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, Palermo L, Prineas R, Rubin SM, Scott JC, Vogt T, Wallace R, Yates AJ, LaCroix AZ (1998) Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 280(24):2077–2082PubMedCrossRef
28.
Zurück zum Zitat Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T, Keller M, Chesnut CH 3rd, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 282(14):1344–1352PubMedCrossRef Harris ST, Watts NB, Genant HK, McKeever CD, Hangartner T, Keller M, Chesnut CH 3rd, Brown J, Eriksen EF, Hoseyni MS, Axelrod DW, Miller PD (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 282(14):1344–1352PubMedCrossRef
29.
Zurück zum Zitat McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ (2001) Reginster JY; Hip Intervention Program Study Group. Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med 344(5):333–340PubMedCrossRef McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ (2001) Reginster JY; Hip Intervention Program Study Group. Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med 344(5):333–340PubMedCrossRef
30.
Zurück zum Zitat Black DM, Delmas PD, Eastell R, Reid IR, Boonen S, Cauley JA, Cosman F, Lakatos P, Leung PC, Man Z, Mautalen C, Mesenbrink P, Hu H, Caminis J, Tong K, Rosario-Jansen T, Krasnow J, Hue TF, Sellmeyer D, Eriksen EF (2007) Cummings SR; HORIZON Pivotal Fracture Trial. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 356(18):1809–1822PubMedCrossRef Black DM, Delmas PD, Eastell R, Reid IR, Boonen S, Cauley JA, Cosman F, Lakatos P, Leung PC, Man Z, Mautalen C, Mesenbrink P, Hu H, Caminis J, Tong K, Rosario-Jansen T, Krasnow J, Hue TF, Sellmeyer D, Eriksen EF (2007) Cummings SR; HORIZON Pivotal Fracture Trial. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 356(18):1809–1822PubMedCrossRef
31.
Zurück zum Zitat Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD (2010) Scientific Advisory Council of Osteoporosis Canada. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ 23;182(17):1864-73. Papaioannou A, Morin S, Cheung AM, Atkinson S, Brown JP, Feldman S, Hanley DA, Hodsman A, Jamal SA, Kaiser SM, Kvern B, Siminoski K, Leslie WD (2010) Scientific Advisory Council of Osteoporosis Canada. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ 23;182(17):1864-73.
32.
Zurück zum Zitat United States Public Health Service. Office of the Surgeon General. Bone health and osteoporosis: a report of the surgeon general. Rockville, MD.: U.S. Dept. of Health and Human Services Public Health Service Office of the Surgeon General; 2004. United States Public Health Service. Office of the Surgeon General. Bone health and osteoporosis: a report of the surgeon general. Rockville, MD.: U.S. Dept. of Health and Human Services Public Health Service Office of the Surgeon General; 2004.
33.
Zurück zum Zitat Tarride JE, Hopkins RB, Leslie WD, Morin S, Adachi JD, Papaioannou A, Bessette L, Brown JP, Goeree R (2012) The burden of illness of osteoporosis in Canada. Osteoporos Int 23(11):2591–2600PubMedPubMedCentralCrossRef Tarride JE, Hopkins RB, Leslie WD, Morin S, Adachi JD, Papaioannou A, Bessette L, Brown JP, Goeree R (2012) The burden of illness of osteoporosis in Canada. Osteoporos Int 23(11):2591–2600PubMedPubMedCentralCrossRef
34.
Zurück zum Zitat Wiktorowicz ME, Goerre R, Papaioannou A, Adachi JD, Papadimitropoulos E (2001) Economic implications of hip fracture: health service use, institutional care and cost in Canada. Osteoporos Int 12(4):271–278PubMedCrossRef Wiktorowicz ME, Goerre R, Papaioannou A, Adachi JD, Papadimitropoulos E (2001) Economic implications of hip fracture: health service use, institutional care and cost in Canada. Osteoporos Int 12(4):271–278PubMedCrossRef
35.
Zurück zum Zitat Jean S, O'Donnell S, Lagacé C, Walsh P, Bancej C, Brown JP, Morin S, Papaioannou A, Jaglal SB (2013) Leslie WD; Osteoporosis Surveillance Expert Working Group. Trends in hip fracture rates in Canada: an age-period-cohort analysis. J Bone Miner Res 28(6):1283–1289PubMedCrossRef Jean S, O'Donnell S, Lagacé C, Walsh P, Bancej C, Brown JP, Morin S, Papaioannou A, Jaglal SB (2013) Leslie WD; Osteoporosis Surveillance Expert Working Group. Trends in hip fracture rates in Canada: an age-period-cohort analysis. J Bone Miner Res 28(6):1283–1289PubMedCrossRef
36.
Zurück zum Zitat Beaupre LA, Cinats JG, Senthilselvan A, Lier D, Jones CA, Scharfenberger A, Johnston DW, Saunders LD (2006) Reduced morbidity for elderly patients with a hip fracture after implementation of a perioperative evidence-based clinical pathway. Qual Saf Health Care 15(5):375–379PubMedPubMedCentralCrossRef Beaupre LA, Cinats JG, Senthilselvan A, Lier D, Jones CA, Scharfenberger A, Johnston DW, Saunders LD (2006) Reduced morbidity for elderly patients with a hip fracture after implementation of a perioperative evidence-based clinical pathway. Qual Saf Health Care 15(5):375–379PubMedPubMedCentralCrossRef
38.
Zurück zum Zitat Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ 1;181(5):265-71. Ioannidis G, Papaioannou A, Hopman WM, Akhtar-Danesh N, Anastassiades T, Pickard L, Kennedy CC, Prior JC, Olszynski WP, Davison KS, Goltzman D, Thabane L, Gafni A, Papadimitropoulos EA, Brown JP, Josse RG, Hanley DA, Adachi JD (2009) Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ 1;181(5):265-71.
39.
Zurück zum Zitat Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Eisman JA, McCloskey EV, Mellstrom D, Melton LJ 3rd, Pols HA, Reeve J, Silman AJ, Tenenhouse A (2004) A family history of fracture and fracture risk: a meta-analysis. Bone. 35(5):1029–1037PubMedCrossRef Kanis JA, Johansson H, Oden A, Johnell O, De Laet C, Eisman JA, McCloskey EV, Mellstrom D, Melton LJ 3rd, Pols HA, Reeve J, Silman AJ, Tenenhouse A (2004) A family history of fracture and fracture risk: a meta-analysis. Bone. 35(5):1029–1037PubMedCrossRef
40.
Zurück zum Zitat Chen P, Krege JH, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Papadimitropoulos E, Kreiger N, Olszynski WP, Josse RG, Goltzman D, CaMOS Research Group (2009) Vertebral fracture status and the World Health Organization risk factors for predicting osteoporotic fracture risk. J Bone Miner Res 24(3):495–502PubMedCrossRef Chen P, Krege JH, Adachi JD, Prior JC, Tenenhouse A, Brown JP, Papadimitropoulos E, Kreiger N, Olszynski WP, Josse RG, Goltzman D, CaMOS Research Group (2009) Vertebral fracture status and the World Health Organization risk factors for predicting osteoporotic fracture risk. J Bone Miner Res 24(3):495–502PubMedCrossRef
41.
Zurück zum Zitat Gallagher JC, Melton LJ, Riggs BL, Bergstrath E (1980) Epidemiology of fractures of the proximal femur in Rochester, Minnesota. Clin Orthop Relat Res 150:163–171CrossRef Gallagher JC, Melton LJ, Riggs BL, Bergstrath E (1980) Epidemiology of fractures of the proximal femur in Rochester, Minnesota. Clin Orthop Relat Res 150:163–171CrossRef
42.
Zurück zum Zitat McLellan A, Reid D, Forbes K, Reid R, Campbell C, Gregori A, Raby N, Simpson A (2004) Effectiveness of strategies for the secondary prevention of osteoporotic fractures in Scotland (CEPS 99/03). NHS Quality Improvement Scotland, Glasgow McLellan A, Reid D, Forbes K, Reid R, Campbell C, Gregori A, Raby N, Simpson A (2004) Effectiveness of strategies for the secondary prevention of osteoporotic fractures in Scotland (CEPS 99/03). NHS Quality Improvement Scotland, Glasgow
43.
Zurück zum Zitat Port L, Center J, Briffa NK, Nguyen T, Cumming R, Eisman J (2003) Osteoporotic fracture: missed opportunity for intervention. Osteoporos Int 14(9):780–784PubMedCrossRef Port L, Center J, Briffa NK, Nguyen T, Cumming R, Eisman J (2003) Osteoporotic fracture: missed opportunity for intervention. Osteoporos Int 14(9):780–784PubMedCrossRef
44.
Zurück zum Zitat Edwards BJ, Bunta AD, Simonelli C, Bolander M, Fitzpatrick LA (2007) Prior fractures are common in patients with subsequent hip fractures. Clin Orthop Relat Res 461:226–230PubMedCrossRef Edwards BJ, Bunta AD, Simonelli C, Bolander M, Fitzpatrick LA (2007) Prior fractures are common in patients with subsequent hip fractures. Clin Orthop Relat Res 461:226–230PubMedCrossRef
45.
Zurück zum Zitat Greene D, Dell RM (2010) Outcomes of an osteoporosis disease-management program managed by nurse practitioners. J Am Acad Nurse Pract 22(6):326–329PubMedCrossRef Greene D, Dell RM (2010) Outcomes of an osteoporosis disease-management program managed by nurse practitioners. J Am Acad Nurse Pract 22(6):326–329PubMedCrossRef
46.
Zurück zum Zitat Walters S, Khan T, Ong T, Sahota O (2017) Fracture liaison services: improving outcomes for patients with osteoporosis. Clin Interv Aging 12:117–127PubMedPubMedCentralCrossRef Walters S, Khan T, Ong T, Sahota O (2017) Fracture liaison services: improving outcomes for patients with osteoporosis. Clin Interv Aging 12:117–127PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Bogoch ER, Elliot-Gibson V, Beaton DE, Jamal SA, Josse RG, Murray TM (2006) Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. J Bone Joint Surg Am 88(1):25–34PubMed Bogoch ER, Elliot-Gibson V, Beaton DE, Jamal SA, Josse RG, Murray TM (2006) Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. J Bone Joint Surg Am 88(1):25–34PubMed
48.
Zurück zum Zitat Ryg J, Rejnmark L, Overgaard S, Brixen K, Vestergaard P (2009) Hip fracture patients at risk of second hip fracture: a nationwide population-based cohort study of 169,145 cases during 1977-2001. J Bone Miner Res 24(7):1299–1307PubMedCrossRef Ryg J, Rejnmark L, Overgaard S, Brixen K, Vestergaard P (2009) Hip fracture patients at risk of second hip fracture: a nationwide population-based cohort study of 169,145 cases during 1977-2001. J Bone Miner Res 24(7):1299–1307PubMedCrossRef
49.
Zurück zum Zitat Hoff M, Meyer HE, Skurtveit S, Langhammer A, Søgaard AJ, Syversen U, Dhainaut A, Skovlund E, Abrahamsen B, Schei B (2017) Validation of FRAX and the impact of self-reported falls among elderly in a general population: the HUNT study. Norway Osteoporos Int 28(10):2935–2944PubMedCrossRef Hoff M, Meyer HE, Skurtveit S, Langhammer A, Søgaard AJ, Syversen U, Dhainaut A, Skovlund E, Abrahamsen B, Schei B (2017) Validation of FRAX and the impact of self-reported falls among elderly in a general population: the HUNT study. Norway Osteoporos Int 28(10):2935–2944PubMedCrossRef
50.
Zurück zum Zitat Hajcsar EE, Hawker G, Bogoch ER (2000) Investigation and treatment of osteoporosis in patients with fragility fractures. CMAJ 3;163(7):819-22. Hajcsar EE, Hawker G, Bogoch ER (2000) Investigation and treatment of osteoporosis in patients with fragility fractures. CMAJ 3;163(7):819-22.
51.
Zurück zum Zitat Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int 19(1):79–86PubMedCrossRef Bessette L, Ste-Marie LG, Jean S, Davison KS, Beaulieu M, Baranci M, Bessant J, Brown JP (2008) The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int 19(1):79–86PubMedCrossRef
52.
Zurück zum Zitat Solomon DH, Johnston SS, Boytsov NN, McMorrow D, Lane JM, Krohn KD (2014) Osteoporosis medication use after hip fracture in U.S. patients between 2002 and 2011. J Bone Miner Res 29(9):1929–1937PubMedCrossRef Solomon DH, Johnston SS, Boytsov NN, McMorrow D, Lane JM, Krohn KD (2014) Osteoporosis medication use after hip fracture in U.S. patients between 2002 and 2011. J Bone Miner Res 29(9):1929–1937PubMedCrossRef
53.
Zurück zum Zitat Kanis JA, Svedbom A, Harvey N, McCloskey EV (2014) The osteoporosis treatment gap. J Bone Miner Res 29(9):1926–1928PubMedCrossRef Kanis JA, Svedbom A, Harvey N, McCloskey EV (2014) The osteoporosis treatment gap. J Bone Miner Res 29(9):1926–1928PubMedCrossRef
54.
Zurück zum Zitat Dell RM, Adams AL, Greene DF, Funahashi TT, Silverman SL, Eisemon EO, Zhou H, Burchette RJ, Ott SM (2012) Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res 27:2544–2550PubMedCrossRef Dell RM, Adams AL, Greene DF, Funahashi TT, Silverman SL, Eisemon EO, Zhou H, Burchette RJ, Ott SM (2012) Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res 27:2544–2550PubMedCrossRef
55.
Zurück zum Zitat Khan AA, Leslie WD, Lentle B, Iles S, Kaiser SM, Frame H, Burrell S, Cheung AM (2015) Atypical femoral fractures: a teaching perspective. Can Assoc Radiol J 66(2):102–107PubMedCrossRef Khan AA, Leslie WD, Lentle B, Iles S, Kaiser SM, Frame H, Burrell S, Cheung AM (2015) Atypical femoral fractures: a teaching perspective. Can Assoc Radiol J 66(2):102–107PubMedCrossRef
56.
Zurück zum Zitat Khan AA, Kaiser S (2017) Atypical femoral fracture. CMAJ 10;189(14):E542 Khan AA, Kaiser S (2017) Atypical femoral fracture. CMAJ 10;189(14):E542
57.
Zurück zum Zitat Khan AA, Morrison A, Hanley DA, Felsenberg D, McCauley LK, O'Ryan F, Reid IR, Ruggiero SL, Taguchi A, Tetradis S, Watts NB, Brandi ML, Peters E, Guise T, Eastell R, Cheung AM, Morin SN, Masri B, Cooper C, Morgan SL, Obermayer-Pietsch B, Langdahl BL, Al Dabagh R, Davison KS, Kendler DL, Sándor GK, Josse RG, Bhandari M, El Rabbany M, Pierroz DD, Sulimani R, Saunders DP, Brown JP, Compston J, International Task Force on Osteonecrosis of the Jaw (2015) Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus. J Bone Miner Res 30(1):3–23PubMedCrossRef Khan AA, Morrison A, Hanley DA, Felsenberg D, McCauley LK, O'Ryan F, Reid IR, Ruggiero SL, Taguchi A, Tetradis S, Watts NB, Brandi ML, Peters E, Guise T, Eastell R, Cheung AM, Morin SN, Masri B, Cooper C, Morgan SL, Obermayer-Pietsch B, Langdahl BL, Al Dabagh R, Davison KS, Kendler DL, Sándor GK, Josse RG, Bhandari M, El Rabbany M, Pierroz DD, Sulimani R, Saunders DP, Brown JP, Compston J, International Task Force on Osteonecrosis of the Jaw (2015) Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus. J Bone Miner Res 30(1):3–23PubMedCrossRef
58.
Zurück zum Zitat Khan AA, Morrison A, Kendler DL, Rizzoli R, Hanley DA, Felsenberg D, McCauley LK, O'Ryan F, Reid IR, Ruggiero SL, Taguchi A, Tetradis S, Watts NB, Brandi ML, Peters E15, Guise T, Eastell R, Cheung AM, Morin SN, Masri B, Cooper C, Morgan SL, Obermayer-Pietsch B, Langdahl BL, Dabagh RA, Davison KS, Sándor GK, Josse RG, Bhandari M, El Rabbany M, Pierroz DD, Sulimani R, Saunders DP, Brown JP, Compston J (2017) International Task Force on Osteonecrosis of the. Case-based review of osteonecrosis of the jaw (ONJ) and application of the international recommendations for management from the International Task Force on ONJ. J Clin Densitom 20(1):8–24PubMedCrossRef Khan AA, Morrison A, Kendler DL, Rizzoli R, Hanley DA, Felsenberg D, McCauley LK, O'Ryan F, Reid IR, Ruggiero SL, Taguchi A, Tetradis S, Watts NB, Brandi ML, Peters E15, Guise T, Eastell R, Cheung AM, Morin SN, Masri B, Cooper C, Morgan SL, Obermayer-Pietsch B, Langdahl BL, Dabagh RA, Davison KS, Sándor GK, Josse RG, Bhandari M, El Rabbany M, Pierroz DD, Sulimani R, Saunders DP, Brown JP, Compston J (2017) International Task Force on Osteonecrosis of the. Case-based review of osteonecrosis of the jaw (ONJ) and application of the international recommendations for management from the International Task Force on ONJ. J Clin Densitom 20(1):8–24PubMedCrossRef
59.
Zurück zum Zitat Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster DW, Ebeling PR, Einhorn TA, Genant HK, Geusens P, Klaushofer K, Lane JM, McKiernan F, McKinney R, Ng A, Nieves J, O'Keefe R, Papapoulos S, Howe TS, van der Meulen MC, Weinstein RS, Whyte MP (2014) Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 29(1):1–23PubMedCrossRef Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster DW, Ebeling PR, Einhorn TA, Genant HK, Geusens P, Klaushofer K, Lane JM, McKiernan F, McKinney R, Ng A, Nieves J, O'Keefe R, Papapoulos S, Howe TS, van der Meulen MC, Weinstein RS, Whyte MP (2014) Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 29(1):1–23PubMedCrossRef
60.
61.
Zurück zum Zitat Kanis JA, Borgström F, Compston J, Dreinhöfer K, Nolte E, Jonsson L, Lems WF, McCloskey EV, Rizzoli R, Stenmark J (2013) SCOPE: a scorecard for osteoporosis in Europe. Arch Osteoporos 8(1-2):144PubMedPubMedCentralCrossRef Kanis JA, Borgström F, Compston J, Dreinhöfer K, Nolte E, Jonsson L, Lems WF, McCloskey EV, Rizzoli R, Stenmark J (2013) SCOPE: a scorecard for osteoporosis in Europe. Arch Osteoporos 8(1-2):144PubMedPubMedCentralCrossRef
62.
Zurück zum Zitat Dore N, Kennedy C, Fisher P, Dolovich L, Farrauto L, Papaioannou A (2013) Improving care after hip fracture: the fracture? Think osteoporosis (FTOP) program. BMC Geriatr 13:130PubMedPubMedCentralCrossRef Dore N, Kennedy C, Fisher P, Dolovich L, Farrauto L, Papaioannou A (2013) Improving care after hip fracture: the fracture? Think osteoporosis (FTOP) program. BMC Geriatr 13:130PubMedPubMedCentralCrossRef
63.
Zurück zum Zitat De Bruin IJA, Wyers CE, van den Bergh JPW, Geusens PPMM (2017) Fracture liaison services: do they reduce fracture rates? Ther Adv Musculoskelet Dis 9(7):157–164PubMedPubMedCentralCrossRef De Bruin IJA, Wyers CE, van den Bergh JPW, Geusens PPMM (2017) Fracture liaison services: do they reduce fracture rates? Ther Adv Musculoskelet Dis 9(7):157–164PubMedPubMedCentralCrossRef
64.
Zurück zum Zitat Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24(2):393–406PubMedCrossRef Ganda K, Puech M, Chen JS, Speerin R, Bleasel J, Center JR, Eisman JA, March L, Seibel MJ (2013) Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis. Osteoporos Int 24(2):393–406PubMedCrossRef
65.
Zurück zum Zitat Dell R (2011) Fracture prevention in Kaiser Permanente Southern California. Osteoporos Int 22(suppl 3):457–460PubMedCrossRef Dell R (2011) Fracture prevention in Kaiser Permanente Southern California. Osteoporos Int 22(suppl 3):457–460PubMedCrossRef
66.
Zurück zum Zitat Javaid MK, Sami A, Lems W, Mitchell P, Thomas T, Singer A, Speerin R, Fujita M, Pierroz DD, Akesson K, Halbout P, Ferrari S, Cooper C (2020) A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network. Osteoporos Int 31:1193–1204PubMedPubMedCentralCrossRef Javaid MK, Sami A, Lems W, Mitchell P, Thomas T, Singer A, Speerin R, Fujita M, Pierroz DD, Akesson K, Halbout P, Ferrari S, Cooper C (2020) A patient-level key performance indicator set to measure the effectiveness of fracture liaison services and guide quality improvement: a position paper of the IOF Capture the Fracture Working Group, National Osteoporosis Foundation and Fragility Fracture Network. Osteoporos Int 31:1193–1204PubMedPubMedCentralCrossRef
67.
Zurück zum Zitat Bubbear JS (2016) Atypical femur fractures in patients treated with bisphosphonates: identification, management, and prevention. Rambam Maimonides Med J 7(4):e0032PubMedCentralCrossRef Bubbear JS (2016) Atypical femur fractures in patients treated with bisphosphonates: identification, management, and prevention. Rambam Maimonides Med J 7(4):e0032PubMedCentralCrossRef
69.
Zurück zum Zitat Johansson H, Siggeirsdóttir K, Harvey NC, Odén A, Gudnason V, McCloskey E, Sigurdsson G, Kanis JA (2017) Imminent risk of fracture after fracture. Osteoporos Int 28(3):775–780PubMedCrossRef Johansson H, Siggeirsdóttir K, Harvey NC, Odén A, Gudnason V, McCloskey E, Sigurdsson G, Kanis JA (2017) Imminent risk of fracture after fracture. Osteoporos Int 28(3):775–780PubMedCrossRef
70.
Zurück zum Zitat Ahmed LA, Center JR, Bjørnerem A, Bluic D, Joakimsen RM, Jørgensen L, Meyer HE, Nguyen ND, Nguyen TV, Omsland TK, Størmer J, Tell GS, van Geel TA, Eisman JA, Emaus N (2013) Progressively increasing fracture risk with advancing age after initial incident fragility fracture: the Tromsø study. J Bone Miner Res 28(10):2214–2221PubMedCrossRef Ahmed LA, Center JR, Bjørnerem A, Bluic D, Joakimsen RM, Jørgensen L, Meyer HE, Nguyen ND, Nguyen TV, Omsland TK, Størmer J, Tell GS, van Geel TA, Eisman JA, Emaus N (2013) Progressively increasing fracture risk with advancing age after initial incident fragility fracture: the Tromsø study. J Bone Miner Res 28(10):2214–2221PubMedCrossRef
71.
Zurück zum Zitat Kanis JA, Johnell O (1999) The burden of osteoporosis. J Endocrinol Investig 22(8):583–588CrossRef Kanis JA, Johnell O (1999) The burden of osteoporosis. J Endocrinol Investig 22(8):583–588CrossRef
72.
Zurück zum Zitat Nymark T, Lauritsen JM, Ovesen O, Röck ND, Jeune B (2006) Short time-frame from first to second hip fracture in the Funen County Hip Fracture Study. Osteoporos Int 17(9):1353–1357PubMedCrossRef Nymark T, Lauritsen JM, Ovesen O, Röck ND, Jeune B (2006) Short time-frame from first to second hip fracture in the Funen County Hip Fracture Study. Osteoporos Int 17(9):1353–1357PubMedCrossRef
Metadaten
Titel
Osteoporosis treatment rate following hip fracture in a community hospital
verfasst von
Aliya A. Khan
Hajar AbuAlrob
Farhan Tariq
Madiha Tauqir
Paul Zalzal
Iman M’Hiri
Moin Khan
Mark Ginty
Brad Weening
Publikationsdatum
01.12.2021
Verlag
Springer London
Erschienen in
Archives of Osteoporosis / Ausgabe 1/2021
Print ISSN: 1862-3522
Elektronische ISSN: 1862-3514
DOI
https://doi.org/10.1007/s11657-020-00861-x

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