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Erschienen in: Current Allergy and Asthma Reports 7/2019

01.07.2019 | Otitis (DP Skoner, Section Editor)

Role of Obesity in Otorhinolaryngologic Diseases

verfasst von: Su Young Jung, Dong Choon Park, Sang Hoon Kim, Seung Geun Yeo

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 7/2019

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Abstract

Purpose of Review

Obesity is a major public health problem associated with various diseases. Improving obesity control and achieving greater patient satisfaction are critical unmet needs. Various otorhinolaryngologic diseases can have negative effects on quality of life or actual health status depending on their type. Over the past decade, the relationship between obesity and otorhinolaryngologic conditions has been investigated. The purpose of this review was to discuss the relationship between obesity and otorhinolaryngological diseases.

Recent Findings

This is a narrative review on the current state of incidence, effects, and associated mechanisms between obesity and otorhinolaryngologic diseases. In various otologic diseases, otitis media (OM) and hearing loss (HL) are associated with obesity. In rhinologic parts, chronic rhinosinusitis (CRS) and obstructive sleep apnea (OSA) were significantly associated with obesity. Most of these diseases are reported to have higher susceptibility and severity as body mass index (BMI) increases. However, the incidence of head and neck cancer (HNC) was inversely associated with obesity, especially central adiposity. The relevance of obesity in laryngopharyngeal reflux disease (LPR) and allergic rhinitis (AR) has yet to be clarified, and this remains controversial.

Summary

This review provides a comprehensive overview of the current state of incidence, effects, and associated mechanisms between obesity and otorhinolaryngologic diseases. Various otorhinolaryngological diseases are related to obesity. As obesity can be a negative risk factor in these otorhinolaryngologic diseases, early diagnosis and treatment of these diseases in obese patients will be critical.
Literatur
1.
Zurück zum Zitat Ryan DH, Kahan S. Guideline recommendations for obesity management. Med Clin North Am. 2018;102(1):49–63.PubMed Ryan DH, Kahan S. Guideline recommendations for obesity management. Med Clin North Am. 2018;102(1):49–63.PubMed
2.
Zurück zum Zitat Tsai AG, Williamson DF, Glick HA. Direct medical cost of overweight and obesity in the USA: a quantitative systematic review. Obes Rev. 2010;12(1):50–61. Tsai AG, Williamson DF, Glick HA. Direct medical cost of overweight and obesity in the USA: a quantitative systematic review. Obes Rev. 2010;12(1):50–61.
3.
Zurück zum Zitat Sturm R, Ringel JS, Andreyeva T. Increasing obesity rates and disability trends. Health Aff (Millwood). 2004;23(2):199–205. Sturm R, Ringel JS, Andreyeva T. Increasing obesity rates and disability trends. Health Aff (Millwood). 2004;23(2):199–205.
4.
Zurück zum Zitat Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr. 2006;83(2):461S–5S.PubMed Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr. 2006;83(2):461S–5S.PubMed
5.
Zurück zum Zitat Monteiro R, Azevedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm. 2010;2010:289645.PubMedPubMedCentral Monteiro R, Azevedo I. Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm. 2010;2010:289645.PubMedPubMedCentral
6.
Zurück zum Zitat Gregor MF, Hotamisligil GS. Inflammatory mechanisms in obesity. Annu Rev. Immunol. 2011;29:415–45.PubMed Gregor MF, Hotamisligil GS. Inflammatory mechanisms in obesity. Annu Rev. Immunol. 2011;29:415–45.PubMed
7.
Zurück zum Zitat Harper JW, Zisman TL. Interaction of obesity and inflammatory bowel disease. World J Gastroenterol. 2016;22(35):7868–81.PubMedPubMedCentral Harper JW, Zisman TL. Interaction of obesity and inflammatory bowel disease. World J Gastroenterol. 2016;22(35):7868–81.PubMedPubMedCentral
8.
Zurück zum Zitat Gupta S, Lodha R, Kabra SK. Asthma, GERD and obesity: triangle of inflammation. Indian J Pediatr. 2018;85(10):887–92.PubMed Gupta S, Lodha R, Kabra SK. Asthma, GERD and obesity: triangle of inflammation. Indian J Pediatr. 2018;85(10):887–92.PubMed
9.
Zurück zum Zitat Lee S, Lane A. Chronic rhinosinusitis as a multifactorial inflammatory disorder. Curr Infect Dis Rep. 2011;13(2):159–68.PubMedPubMedCentral Lee S, Lane A. Chronic rhinosinusitis as a multifactorial inflammatory disorder. Curr Infect Dis Rep. 2011;13(2):159–68.PubMedPubMedCentral
10.
Zurück zum Zitat Bassiouni A, Naidoo Y, Wormald PJ. When FESS fails: the inflammatory load hypothesis in refractory chronic rhinosinusitis. Laryngoscope. 2012;122(2):460–6.PubMed Bassiouni A, Naidoo Y, Wormald PJ. When FESS fails: the inflammatory load hypothesis in refractory chronic rhinosinusitis. Laryngoscope. 2012;122(2):460–6.PubMed
11.
Zurück zum Zitat Krouse JH, Brown RW, Fineman SM, Han JK, Heller AJ, Joe S, et al. Asthma and the unified airway. Otolaryngol Head Neck Surg. 2007;136(5S):S75–106.PubMed Krouse JH, Brown RW, Fineman SM, Han JK, Heller AJ, Joe S, et al. Asthma and the unified airway. Otolaryngol Head Neck Surg. 2007;136(5S):S75–106.PubMed
14.
Zurück zum Zitat Liu W, Zeng Q, Zhou L, Luo R, Dong H. Association of leptin with disease severity and inflammation indicators in Chinese obese children with allergic rhinitis. Pediatr Allergy Immunol. 2018;29(2):186–93.PubMed Liu W, Zeng Q, Zhou L, Luo R, Dong H. Association of leptin with disease severity and inflammation indicators in Chinese obese children with allergic rhinitis. Pediatr Allergy Immunol. 2018;29(2):186–93.PubMed
15.
Zurück zum Zitat Lim MS, Lee CH, Sim S, Hong SK, Choi HG. Physical activity, sedentary habits, sleep, and obesity are associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents. Yonsei Med J. 2017;58(5):1040–6.PubMedPubMedCentral Lim MS, Lee CH, Sim S, Hong SK, Choi HG. Physical activity, sedentary habits, sleep, and obesity are associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents. Yonsei Med J. 2017;58(5):1040–6.PubMedPubMedCentral
16.
Zurück zum Zitat Lei Y, Yang H, Zhen L. Obesity is a risk factor for allergic rhinitis in children of Wuhan (China). Asia Pac Allergy. 2016;6(2):101–4.PubMedPubMedCentral Lei Y, Yang H, Zhen L. Obesity is a risk factor for allergic rhinitis in children of Wuhan (China). Asia Pac Allergy. 2016;6(2):101–4.PubMedPubMedCentral
17.
Zurück zum Zitat Park DY, Kim YS, Kim JH, Kang JW. Association of body mass index and other factors with histamine skin reactivity in adults with allergic nasal symptoms. Am J Rhinol Allergy. 2015;29(6):e160–3.PubMed Park DY, Kim YS, Kim JH, Kang JW. Association of body mass index and other factors with histamine skin reactivity in adults with allergic nasal symptoms. Am J Rhinol Allergy. 2015;29(6):e160–3.PubMed
18.
Zurück zum Zitat Kim TH, Kang HM, Oh IH, Yeo SG. Relationship between otorhinolaryngologic diseases and obesity. Clin Exp Otorhinolaryngol. 2015;8(3):194–7.PubMedPubMedCentral Kim TH, Kang HM, Oh IH, Yeo SG. Relationship between otorhinolaryngologic diseases and obesity. Clin Exp Otorhinolaryngol. 2015;8(3):194–7.PubMedPubMedCentral
19.
Zurück zum Zitat Bhattacharyya N. Associations between obesity and inflammatory sinonasal disorders. Laryngoscope. 2013;123(8):1840–4.PubMed Bhattacharyya N. Associations between obesity and inflammatory sinonasal disorders. Laryngoscope. 2013;123(8):1840–4.PubMed
20.
Zurück zum Zitat Huang SL, Shiao G, Chou P. Association between body mass index and allergy in teenage girls in Taiwan. Clin Exp Allergy. 1999;29(3):323–9.PubMed Huang SL, Shiao G, Chou P. Association between body mass index and allergy in teenage girls in Taiwan. Clin Exp Allergy. 1999;29(3):323–9.PubMed
22.
Zurück zum Zitat Chung SD, Chen PY, Lin HC, Hung SH. Comorbidity profile of chronic rhinosinusitis: a population-based study. Laryngoscope. 2014;124(7):1536–41.PubMed Chung SD, Chen PY, Lin HC, Hung SH. Comorbidity profile of chronic rhinosinusitis: a population-based study. Laryngoscope. 2014;124(7):1536–41.PubMed
23.
Zurück zum Zitat Matsumoto M, Konno S, Kimura H, Takei N, Kimura H, Shimizu K, et al. Associations of current wheeze and body mass index with perennial and seasonal allergic rhinitis in young adults. Int Arch Allergy Immunol. 2018;176(2):143–9.PubMed Matsumoto M, Konno S, Kimura H, Takei N, Kimura H, Shimizu K, et al. Associations of current wheeze and body mass index with perennial and seasonal allergic rhinitis in young adults. Int Arch Allergy Immunol. 2018;176(2):143–9.PubMed
24.
Zurück zum Zitat Han YY, Forno E, Gogna M, Celedón JC. Obesity and rhinitis in a nationwide study of children and adults in the United States. J Allergy Clin Immunol. 2016;137(5):1460–5.PubMedPubMedCentral Han YY, Forno E, Gogna M, Celedón JC. Obesity and rhinitis in a nationwide study of children and adults in the United States. J Allergy Clin Immunol. 2016;137(5):1460–5.PubMedPubMedCentral
25.
Zurück zum Zitat Kanagalingam S, Shehab SS, Kaminsky DA, Wise RA, Lang JE, Dixon AE. Effect of obesity on sinonasal disease in asthma. J Asthma. 2018;55(5):525–31.PubMed Kanagalingam S, Shehab SS, Kaminsky DA, Wise RA, Lang JE, Dixon AE. Effect of obesity on sinonasal disease in asthma. J Asthma. 2018;55(5):525–31.PubMed
26.
Zurück zum Zitat Sybilski AJ, Raciborski F, Lipiec A, Tomaszewska A, Lusawa A, Furmańczyk K, et al. Obesity—a risk factor for asthma, but not for atopic dermatitis, allergic rhinitis and sensitization. Public Health Nutr. 2015;18(3):530–6.PubMed Sybilski AJ, Raciborski F, Lipiec A, Tomaszewska A, Lusawa A, Furmańczyk K, et al. Obesity—a risk factor for asthma, but not for atopic dermatitis, allergic rhinitis and sensitization. Public Health Nutr. 2015;18(3):530–6.PubMed
27.
Zurück zum Zitat Sidell D, Shapiro NL, Bhattacharyya N. Obesity and the risk of chronic rhinosinusitis, allergic rhinitis, and acute otitis media in school-age children. Laryngoscope. 2013;123(10):2360–3.PubMed Sidell D, Shapiro NL, Bhattacharyya N. Obesity and the risk of chronic rhinosinusitis, allergic rhinitis, and acute otitis media in school-age children. Laryngoscope. 2013;123(10):2360–3.PubMed
28.
Zurück zum Zitat Konno S, Hizawa N, Fukutomi Y, Taniguchi M, Kawagishi Y, Okada C, et al. The prevalence of rhinitis and its association with smoking and obesity in a nationwide survey of Japanese adults. Allergy. 2012;67(5):653–60.PubMed Konno S, Hizawa N, Fukutomi Y, Taniguchi M, Kawagishi Y, Okada C, et al. The prevalence of rhinitis and its association with smoking and obesity in a nationwide survey of Japanese adults. Allergy. 2012;67(5):653–60.PubMed
29.
Zurück zum Zitat Kusunoki T, Morimoto T, Nishikomori R, Heike T, Ito M, Hosoi S, et al. Obesity and the prevalence of allergic diseases in schoolchildren. Pediatr Allergy Immunol. 2008;19(6):527–34.PubMed Kusunoki T, Morimoto T, Nishikomori R, Heike T, Ito M, Hosoi S, et al. Obesity and the prevalence of allergic diseases in schoolchildren. Pediatr Allergy Immunol. 2008;19(6):527–34.PubMed
30.
Zurück zum Zitat Andersen IG, Holm JC, Homøe P. Obstructive sleep apnea in children and adolescents with and without obesity. Eur Arch Otorhinolaryngol. 2019;276(3):871–8.PubMed Andersen IG, Holm JC, Homøe P. Obstructive sleep apnea in children and adolescents with and without obesity. Eur Arch Otorhinolaryngol. 2019;276(3):871–8.PubMed
31.
Zurück zum Zitat Evangelisti M, Shafiek H, Rabasco J, Forlani M, Montesano M, Barreto M, et al. Oximetry in obese children with sleep-disordered breathing. Sleep Med. 2016;27–28:86–91.PubMed Evangelisti M, Shafiek H, Rabasco J, Forlani M, Montesano M, Barreto M, et al. Oximetry in obese children with sleep-disordered breathing. Sleep Med. 2016;27–28:86–91.PubMed
32.
Zurück zum Zitat Mathew R, Castriotta RJ. High hypopnea/apnea ratio (HAR) in extreme obesity. J Clin Sleep Med. 2014;10(4):391–6.PubMedPubMedCentral Mathew R, Castriotta RJ. High hypopnea/apnea ratio (HAR) in extreme obesity. J Clin Sleep Med. 2014;10(4):391–6.PubMedPubMedCentral
33.
Zurück zum Zitat Kim H, Kim MS, Lee JE, Kim JW, Lee CH, Yoon IY, et al. Treatment outcomes and compliance according to obesity in patients with obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2013;270(11):2885–90.PubMed Kim H, Kim MS, Lee JE, Kim JW, Lee CH, Yoon IY, et al. Treatment outcomes and compliance according to obesity in patients with obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2013;270(11):2885–90.PubMed
34.
Zurück zum Zitat Arnardottir ES, Maislin G, Jackson N, Schwab RJ, Benediktsdottir B, Teff K, et al. The role of obesity, different fat compartments and sleep apnea severity in circulating leptin levels: the Icelandic Sleep Apnea Cohort study. Int J Obes (Lond). 2013;37(6):835–42. Arnardottir ES, Maislin G, Jackson N, Schwab RJ, Benediktsdottir B, Teff K, et al. The role of obesity, different fat compartments and sleep apnea severity in circulating leptin levels: the Icelandic Sleep Apnea Cohort study. Int J Obes (Lond). 2013;37(6):835–42.
35.
Zurück zum Zitat Antczak J, Horn B, Richter A, Jernajczyk W, Bodenschatz R, W Schmidt EW. The influence of obesity on sleep quality in male sleep apnea patients before and during therapy. J Physiol Pharmacol. 2008;59(Suppl 6):123–34.PubMed Antczak J, Horn B, Richter A, Jernajczyk W, Bodenschatz R, W Schmidt EW. The influence of obesity on sleep quality in male sleep apnea patients before and during therapy. J Physiol Pharmacol. 2008;59(Suppl 6):123–34.PubMed
36.
Zurück zum Zitat Daltro C, Gregorio PB, Alves E, Abreu M, Bomfim D, Chicourel MH, et al. Prevalence and severity of sleep apnea in a group of morbidly obese patients. Obes Surg. 2007;17(6):809–14.PubMed Daltro C, Gregorio PB, Alves E, Abreu M, Bomfim D, Chicourel MH, et al. Prevalence and severity of sleep apnea in a group of morbidly obese patients. Obes Surg. 2007;17(6):809–14.PubMed
37.
Zurück zum Zitat Redline S, Tishler PV, Schluchter M, Aylor J, Clark K, Graham G. Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems. Am J Respir Crit Care Med. 1999;159(5 Pt 1):1527–32.PubMed Redline S, Tishler PV, Schluchter M, Aylor J, Clark K, Graham G. Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems. Am J Respir Crit Care Med. 1999;159(5 Pt 1):1527–32.PubMed
38.
Zurück zum Zitat Newman AB, Foster G, Givelber R, Nieto FJ, Redline S, Young T. Progression and regression of sleep-disordered breathing with changes in weight: the Sleep Heart Health Study. Arch Intern Med. 2005;165(20):2408–13.PubMed Newman AB, Foster G, Givelber R, Nieto FJ, Redline S, Young T. Progression and regression of sleep-disordered breathing with changes in weight: the Sleep Heart Health Study. Arch Intern Med. 2005;165(20):2408–13.PubMed
39.
Zurück zum Zitat Peppard PE, Young T, Palta M, Dempsey J, Skatrud J. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA. 2000;284(23):3015–21.PubMed Peppard PE, Young T, Palta M, Dempsey J, Skatrud J. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA. 2000;284(23):3015–21.PubMed
40.
Zurück zum Zitat Punjabi NM, Sorkin JD, Katzel LI, Goldberg AP, Schwartz AR, Smith PL. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med. 2002;165(5):677–82.PubMed Punjabi NM, Sorkin JD, Katzel LI, Goldberg AP, Schwartz AR, Smith PL. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med. 2002;165(5):677–82.PubMed
41.
Zurück zum Zitat Richman RM, Elliott LM, Burns CM, Bearpark HM, Steinbeck KS, Caterson ID. The prevalence of obstructive sleep apnoea in an obese female population. Int J Obes Relat Metab Disord. 1994;18(3):173–7.PubMed Richman RM, Elliott LM, Burns CM, Bearpark HM, Steinbeck KS, Caterson ID. The prevalence of obstructive sleep apnoea in an obese female population. Int J Obes Relat Metab Disord. 1994;18(3):173–7.PubMed
42.
Zurück zum Zitat Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med. 1994;154(15):1705–11.PubMed Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med. 1994;154(15):1705–11.PubMed
43.
Zurück zum Zitat Shinohara E, Kihara S, Yamashita S, Yamane M, Nishida M, Arai T, et al. Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects. J Intern Med. 1997;241(1):11–8.PubMed Shinohara E, Kihara S, Yamashita S, Yamane M, Nishida M, Arai T, et al. Visceral fat accumulation as an important risk factor for obstructive sleep apnoea syndrome in obese subjects. J Intern Med. 1997;241(1):11–8.PubMed
44.
Zurück zum Zitat Young T, Shahar E, Nieto FJ, Redline S, Newman AB, Gottlieb DJ, et al. Sleep Heart Health Study Research Group. Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study. Arch Intern Med. 2002;162(8):893–900.PubMed Young T, Shahar E, Nieto FJ, Redline S, Newman AB, Gottlieb DJ, et al. Sleep Heart Health Study Research Group. Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study. Arch Intern Med. 2002;162(8):893–900.PubMed
45.
Zurück zum Zitat Kaya S, Selimoğlu E, Cureoğlu S, Selimoğlu MA. Relationship between chronic otitis media with effusion and overweight or obesity in children. J Laryngol Otol. 2017;131(10):866–70.PubMed Kaya S, Selimoğlu E, Cureoğlu S, Selimoğlu MA. Relationship between chronic otitis media with effusion and overweight or obesity in children. J Laryngol Otol. 2017;131(10):866–70.PubMed
46.
Zurück zum Zitat Choi HG, Sim S, Kim SY, Lee HJ. A high-fat diet is associated with otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2015;79(12):2327–31.PubMed Choi HG, Sim S, Kim SY, Lee HJ. A high-fat diet is associated with otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2015;79(12):2327–31.PubMed
47.
Zurück zum Zitat Kuhle S, Kirk SF, Ohinmaa A, Urschitz MS, Veugelers PJ. The association between childhood overweight and obesity and otitis media. Pediatr Obes. 2012;7(2):151–7.PubMed Kuhle S, Kirk SF, Ohinmaa A, Urschitz MS, Veugelers PJ. The association between childhood overweight and obesity and otitis media. Pediatr Obes. 2012;7(2):151–7.PubMed
48.
Zurück zum Zitat Shin IH, Park DC, Kwon C, Yeo SG. Changes in taste function related to obesity and chronic otitis media with effusion. Arch Otolaryngol Head Neck Surg. 2011;137(3):242–6.PubMed Shin IH, Park DC, Kwon C, Yeo SG. Changes in taste function related to obesity and chronic otitis media with effusion. Arch Otolaryngol Head Neck Surg. 2011;137(3):242–6.PubMed
49.
Zurück zum Zitat Nelson HM, Daly KA, Davey CS, Himes JH, Synder DJ, Bartoshuk LM. Otitis media and associations with overweight status in toddlers. Physiol Behav. 2011;102(5):511–7.PubMed Nelson HM, Daly KA, Davey CS, Himes JH, Synder DJ, Bartoshuk LM. Otitis media and associations with overweight status in toddlers. Physiol Behav. 2011;102(5):511–7.PubMed
50.
Zurück zum Zitat Seaberg RM, Chadha NK, Hubbard BJ, Gordon KA, Allemang BA, Harrison BJ, et al. Chorda tympani nerve function in children: relationship to otitis media and body mass index. Int J Pediatr Otorhinolaryngol. 2010;74(12):1393–6.PubMed Seaberg RM, Chadha NK, Hubbard BJ, Gordon KA, Allemang BA, Harrison BJ, et al. Chorda tympani nerve function in children: relationship to otitis media and body mass index. Int J Pediatr Otorhinolaryngol. 2010;74(12):1393–6.PubMed
51.
Zurück zum Zitat Kim SH, Park DC, Byun JY, Park MS, Cha CI, Yeo SG. The relationship between overweight and otitis media with effusion in children. Int J Obes (Lond). 2011;35(2):279–82. Kim SH, Park DC, Byun JY, Park MS, Cha CI, Yeo SG. The relationship between overweight and otitis media with effusion in children. Int J Obes (Lond). 2011;35(2):279–82.
52.
Zurück zum Zitat Kim JB, Park DC, Cha CI, Yeo SG. Relationship between pediatric obesity and otitis media with effusion. Arch Otolaryngol Head Neck Surg. 2007;133(4):379–82.PubMed Kim JB, Park DC, Cha CI, Yeo SG. Relationship between pediatric obesity and otitis media with effusion. Arch Otolaryngol Head Neck Surg. 2007;133(4):379–82.PubMed
54.
Zurück zum Zitat Hwang JH, Wu CC, Hsu CJ, Liu TC, Yang WS. Association of central obesity with the severity and audiometric configurations of age-related hearing impairment. Obesity (Silver Spring). 2009;17(9):1796–801. Hwang JH, Wu CC, Hsu CJ, Liu TC, Yang WS. Association of central obesity with the severity and audiometric configurations of age-related hearing impairment. Obesity (Silver Spring). 2009;17(9):1796–801.
56.
Zurück zum Zitat Hwang JH. Role of obesity on the prognosis of sudden sensorineural hearing loss in adults. Otolaryngol Head Neck Surg. 2015;153(2):251–6.PubMed Hwang JH. Role of obesity on the prognosis of sudden sensorineural hearing loss in adults. Otolaryngol Head Neck Surg. 2015;153(2):251–6.PubMed
57.
Zurück zum Zitat Lalwani AK, Katz K, Liu YH, Kim S, Weitzman M. Obesity is associated with sensorineural hearing loss in adolescents. Laryngoscope. 2013;123:3178–84.PubMed Lalwani AK, Katz K, Liu YH, Kim S, Weitzman M. Obesity is associated with sensorineural hearing loss in adolescents. Laryngoscope. 2013;123:3178–84.PubMed
58.
Zurück zum Zitat Curhan SG, Eavey R, Wang M, Stampfer MJ, Curhan GC. Body mass index, waist circumference, physical activity, and risk of hearing loss in women. Am J Med. 2013;126(12):1142.e1–8. Curhan SG, Eavey R, Wang M, Stampfer MJ, Curhan GC. Body mass index, waist circumference, physical activity, and risk of hearing loss in women. Am J Med. 2013;126(12):1142.e1–8.
59.
Zurück zum Zitat Kim TS, Park SW, Kim do Y, Kim EB, Chung JW, So HS. Visceral adipose tissue is significantly associated with hearing thresholds in adult women. Clin Endocrinol (Oxf). 2014;80(3):368–75.PubMed Kim TS, Park SW, Kim do Y, Kim EB, Chung JW, So HS. Visceral adipose tissue is significantly associated with hearing thresholds in adult women. Clin Endocrinol (Oxf). 2014;80(3):368–75.PubMed
60.
Zurück zum Zitat Barrenas ML, Jonsson B, Tuvemo T, Hellstrom PA, Lundgren M. High risk of sensorineural hearing loss in men born small for gestational age with and without obesity or height catch-up growth: a prospective longitudinal register study on birth size in 245 000 Swedish conscripts. J Clin Endocrinol Metab. 2005;90(8):4452–6.PubMed Barrenas ML, Jonsson B, Tuvemo T, Hellstrom PA, Lundgren M. High risk of sensorineural hearing loss in men born small for gestational age with and without obesity or height catch-up growth: a prospective longitudinal register study on birth size in 245 000 Swedish conscripts. J Clin Endocrinol Metab. 2005;90(8):4452–6.PubMed
61.
Zurück zum Zitat Rodrigues MM, Dibbern RS, Santos VJ, Passeri LA. Influence of obesity on the correlation between laryngopharyngeal reflux and obstructive sleep apnea. Braz J Otorhinolaryngol. 2014;80(1):5–10.PubMed Rodrigues MM, Dibbern RS, Santos VJ, Passeri LA. Influence of obesity on the correlation between laryngopharyngeal reflux and obstructive sleep apnea. Braz J Otorhinolaryngol. 2014;80(1):5–10.PubMed
62.
Zurück zum Zitat •• The GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017;377(1):13–27. Showed on the impact of obesity on the health of humankind in the last 25 years. The prevalence of obesity has been steadily increasing, and the mortality rate associated with this disease has also increased. •• The GBD 2015 Obesity Collaborators, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, et al. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017;377(1):13–27. Showed on the impact of obesity on the health of humankind in the last 25 years. The prevalence of obesity has been steadily increasing, and the mortality rate associated with this disease has also increased.
63.
Zurück zum Zitat Heymsfield SB, Wadden TA. Mechanisms, pathophysiology, and management of obesity. N Engl J Med. 2017;376(15):1492.PubMed Heymsfield SB, Wadden TA. Mechanisms, pathophysiology, and management of obesity. N Engl J Med. 2017;376(15):1492.PubMed
64.
Zurück zum Zitat Heymsfield SB, Gonzalez MC, Shen W, Redman L, Thomas D. Weight loss composition is one-fourth fat-free mass: a critical review and critique of this widely cited rule. Obes Rev. 2014;15(4):310–21.PubMedPubMedCentral Heymsfield SB, Gonzalez MC, Shen W, Redman L, Thomas D. Weight loss composition is one-fourth fat-free mass: a critical review and critique of this widely cited rule. Obes Rev. 2014;15(4):310–21.PubMedPubMedCentral
65.
Zurück zum Zitat Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S, et al. Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem. 2010;285(23):17271–6.PubMedPubMedCentral Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S, et al. Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins. J Biol Chem. 2010;285(23):17271–6.PubMedPubMedCentral
66.
Zurück zum Zitat Ferrannini E, Camastra S, Gastaldelli A, Maria Sironi A, Natali A, Muscelli E, et al. Beta-cell function in obesity: effects of weight loss. Diabetes. 2004;53(Suppl 3):S26–33.PubMed Ferrannini E, Camastra S, Gastaldelli A, Maria Sironi A, Natali A, Muscelli E, et al. Beta-cell function in obesity: effects of weight loss. Diabetes. 2004;53(Suppl 3):S26–33.PubMed
67.
Zurück zum Zitat Grant RW, Dixit VD. Adipose tissue as an immunological organ. Obesity (Silver Spring). 2015;23(3):512–8.PubMedCentral Grant RW, Dixit VD. Adipose tissue as an immunological organ. Obesity (Silver Spring). 2015;23(3):512–8.PubMedCentral
68.
Zurück zum Zitat Shen W, Wang Z, Punyanita M, Lei J, Sinav A, Kral JG, et al. Adipose tissue quantification by imaging methods: a proposed classification. Obes Res. 2003;11(1):5–16.PubMedPubMedCentral Shen W, Wang Z, Punyanita M, Lei J, Sinav A, Kral JG, et al. Adipose tissue quantification by imaging methods: a proposed classification. Obes Res. 2003;11(1):5–16.PubMedPubMedCentral
69.
Zurück zum Zitat Tchkonia T, Thomou T, Zhu Y, Karagiannides I, Pothoulakis C, Jensen MD, et al. Mechanisms and metabolic implications of regional differences among fat depots. Cell Metab. 2013;17(5):644–56.PubMedPubMedCentral Tchkonia T, Thomou T, Zhu Y, Karagiannides I, Pothoulakis C, Jensen MD, et al. Mechanisms and metabolic implications of regional differences among fat depots. Cell Metab. 2013;17(5):644–56.PubMedPubMedCentral
70.
Zurück zum Zitat Ashrafian H, Toma T, Rowland SP, Harling L, Tan A, Efthimiou E, et al. Bariatric surgery or non-surgical weight loss for obstructive sleep apnoea? A systematic review and comparison of meta-analyses. Obes Surg. 2015 Jul;25(7):1239–50.PubMed Ashrafian H, Toma T, Rowland SP, Harling L, Tan A, Efthimiou E, et al. Bariatric surgery or non-surgical weight loss for obstructive sleep apnoea? A systematic review and comparison of meta-analyses. Obes Surg. 2015 Jul;25(7):1239–50.PubMed
71.
Zurück zum Zitat Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med. 2005;143(3):199–211.PubMed Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med. 2005;143(3):199–211.PubMed
72.
Zurück zum Zitat Klein JO. The burden of otitis media. Vaccine. 2000;19(Suppl 1):S2–8.PubMed Klein JO. The burden of otitis media. Vaccine. 2000;19(Suppl 1):S2–8.PubMed
73.
Zurück zum Zitat Coker TR, Chan LS, Newberry SJ, Limbos MA, Suttorp MJ, Shekelle PG, et al. Diagnosis, microbial epidemiology, and antibiotic treatment of acute otitis media in children: a systematic review. JAMA. 2010;304(19):2161–9.PubMed Coker TR, Chan LS, Newberry SJ, Limbos MA, Suttorp MJ, Shekelle PG, et al. Diagnosis, microbial epidemiology, and antibiotic treatment of acute otitis media in children: a systematic review. JAMA. 2010;304(19):2161–9.PubMed
74.
Zurück zum Zitat Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective cohort study. J Infect Dis. 1989;160(1):83–94.PubMed Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective cohort study. J Infect Dis. 1989;160(1):83–94.PubMed
75.
Zurück zum Zitat Ahmed S, Arjmand E, Sidell D. Role of obesity in otitis media in children. Curr Allergy Asthma Rep. 2014;14(11):469.PubMed Ahmed S, Arjmand E, Sidell D. Role of obesity in otitis media in children. Curr Allergy Asthma Rep. 2014;14(11):469.PubMed
76.
Zurück zum Zitat Lee SK, Yeo SG. Relationship between pediatric obesity and otitis media with effusion. Curr Allergy Asthma Rep. 2009;9(6):465–72.PubMed Lee SK, Yeo SG. Relationship between pediatric obesity and otitis media with effusion. Curr Allergy Asthma Rep. 2009;9(6):465–72.PubMed
77.
Zurück zum Zitat Peracchio HL, Henebery KE, Sharafi M, Hayes JE, Duffy VB. Otitis media exposure associates with dietary preference and adiposity: a community-based observational study of at-risk preschoolers. Physiol Behav. 2012;106(2):264–71.PubMed Peracchio HL, Henebery KE, Sharafi M, Hayes JE, Duffy VB. Otitis media exposure associates with dietary preference and adiposity: a community-based observational study of at-risk preschoolers. Physiol Behav. 2012;106(2):264–71.PubMed
78.
Zurück zum Zitat Griffith IP. Observations on the pathology of chorda tympani nerve in temporal bone sections. J Laryngol Otol. 1977;91(2):151–7.PubMed Griffith IP. Observations on the pathology of chorda tympani nerve in temporal bone sections. J Laryngol Otol. 1977;91(2):151–7.PubMed
79.
Zurück zum Zitat Nash SD, Cruickshanks KJ, Klein R, Klein BE, Nieto FJ, Huang GH, et al. The prevalence of hearing impairment and associated risk factors: the Beaver Dam Offspring Study. Arch Otolaryngol Head Neck Surg. 2011;137(5):432–9.PubMedPubMedCentral Nash SD, Cruickshanks KJ, Klein R, Klein BE, Nieto FJ, Huang GH, et al. The prevalence of hearing impairment and associated risk factors: the Beaver Dam Offspring Study. Arch Otolaryngol Head Neck Surg. 2011;137(5):432–9.PubMedPubMedCentral
80.
Zurück zum Zitat Owens E, Talbott CB, Schubert ED. Vowel discrimination of hearing-impaired listeners. J Speech Hear Res. 1968;11(3):648–55.PubMed Owens E, Talbott CB, Schubert ED. Vowel discrimination of hearing-impaired listeners. J Speech Hear Res. 1968;11(3):648–55.PubMed
81.
Zurück zum Zitat • Dhanda N, Taheri S. A narrative review of obesity and hearing loss. Int J Obes (Lond). 2017;41(7):1066–73. Study showing that obesity can increase the incidence of some kind of hearing loss in general population.PubMed • Dhanda N, Taheri S. A narrative review of obesity and hearing loss. Int J Obes (Lond). 2017;41(7):1066–73. Study showing that obesity can increase the incidence of some kind of hearing loss in general population.PubMed
82.
Zurück zum Zitat Jung SY, Shim HS, Hah YM, Kim SH, Yeo SG. Association of metabolic syndrome with sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg. 2018;144(4):308–14.PubMedPubMedCentral Jung SY, Shim HS, Hah YM, Kim SH, Yeo SG. Association of metabolic syndrome with sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg. 2018;144(4):308–14.PubMedPubMedCentral
83.
Zurück zum Zitat Stachler RJ, Chandrasekhar SS, Archer SM, Rosenfeld RM, Schwartz SR, Barrs DM, et al. American Academy of Otolaryngology-Head and Neck Surgery. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg. 2012;146(3 Suppl):S1–35.PubMed Stachler RJ, Chandrasekhar SS, Archer SM, Rosenfeld RM, Schwartz SR, Barrs DM, et al. American Academy of Otolaryngology-Head and Neck Surgery. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg. 2012;146(3 Suppl):S1–35.PubMed
84.
Zurück zum Zitat Boulet LP. Obesity and atopy. Clin Exp Allergy. 2015;45(1):75–86.PubMed Boulet LP. Obesity and atopy. Clin Exp Allergy. 2015;45(1):75–86.PubMed
85.
Zurück zum Zitat Medoff BD, Okamoto Y, Leyton P, Weng M, Sandall BP, Raher MJ, et al. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol. 2009;41(4):397–406.PubMedPubMedCentral Medoff BD, Okamoto Y, Leyton P, Weng M, Sandall BP, Raher MJ, et al. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol. 2009;41(4):397–406.PubMedPubMedCentral
86.
Zurück zum Zitat Bouloumie A, Marumo T, Lafontan M, Busse R. Leptin induces oxidative stress in human endothelial cells. FASEB J. 1999;13(10):1231–8.PubMed Bouloumie A, Marumo T, Lafontan M, Busse R. Leptin induces oxidative stress in human endothelial cells. FASEB J. 1999;13(10):1231–8.PubMed
87.
Zurück zum Zitat Strachan D, Sibbald B, Weiland S, Aït-Khaled N, Anabwani G, Anderson HR, et al. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol. 1997;8(4):161–76.PubMed Strachan D, Sibbald B, Weiland S, Aït-Khaled N, Anabwani G, Anderson HR, et al. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol. 1997;8(4):161–76.PubMed
88.
Zurück zum Zitat Ulrik CS. Asthma and obesity: is weight reduction the key to achieve asthma control? Curr Opin Pulm Med. 2016;22(1):69–73.PubMed Ulrik CS. Asthma and obesity: is weight reduction the key to achieve asthma control? Curr Opin Pulm Med. 2016;22(1):69–73.PubMed
89.
Zurück zum Zitat Gharibeh T, Mehra R. Obstructive sleep apnea syndrome: natural history, diagnosis, and emerging treatment options. Nat Sci Sleep. 2010;2:233–55.PubMedPubMedCentral Gharibeh T, Mehra R. Obstructive sleep apnea syndrome: natural history, diagnosis, and emerging treatment options. Nat Sci Sleep. 2010;2:233–55.PubMedPubMedCentral
90.
Zurück zum Zitat Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006–14.PubMedPubMedCentral Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep disordered breathing in adults. Am J Epidemiol. 2013;177(9):1006–14.PubMedPubMedCentral
91.
Zurück zum Zitat Lumeng JC, Chervin RD. Epidemiology of pediatric obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):242–52.PubMedPubMedCentral Lumeng JC, Chervin RD. Epidemiology of pediatric obstructive sleep apnea. Proc Am Thorac Soc. 2008;5(2):242–52.PubMedPubMedCentral
92.
Zurück zum Zitat Lam JC, Mak JC, Ip MS. Obesity, obstructive sleep apnoea and metabolic syndrome. Respirology. 2012;17(2):223–36.PubMed Lam JC, Mak JC, Ip MS. Obesity, obstructive sleep apnoea and metabolic syndrome. Respirology. 2012;17(2):223–36.PubMed
94.
Zurück zum Zitat Campagnolo AM, Priston J, Thoen RH, Medeiros T, Assunção AR. Laryngopharyngeal reflux: diagnosis, treatment and latest research. Int Arch Otorhinolaryngol. 2014;18(2):184–91.PubMed Campagnolo AM, Priston J, Thoen RH, Medeiros T, Assunção AR. Laryngopharyngeal reflux: diagnosis, treatment and latest research. Int Arch Otorhinolaryngol. 2014;18(2):184–91.PubMed
95.
Zurück zum Zitat Sidhwa F, Moore A, Alligood E, Fisichella PM. Diagnosis and treatment of the extraesophageal manifestations of gastroesophageal reflux disease. Ann Surg. 2017;265(1):63–7.PubMed Sidhwa F, Moore A, Alligood E, Fisichella PM. Diagnosis and treatment of the extraesophageal manifestations of gastroesophageal reflux disease. Ann Surg. 2017;265(1):63–7.PubMed
96.
Zurück zum Zitat Halum SL, Postma GN, Johnston C, Belafsky PC, Koufman JA. Patients with isolated laryngopharyngeal reflux are not obese. Laryngoscope. 2005;115(6):1042–5.PubMed Halum SL, Postma GN, Johnston C, Belafsky PC, Koufman JA. Patients with isolated laryngopharyngeal reflux are not obese. Laryngoscope. 2005;115(6):1042–5.PubMed
97.
Zurück zum Zitat Etemadi A, O’Doherty MG, Freedman ND, Hollenbeck AR, Dawsey SM, Abnet CC. A prospective cohort study of body size and risk of head and neck cancers in the NIH-AARP diet and health study. Cancer Epidemiol Biomarkers Prev. 2014;23(11):2422–9.PubMedPubMedCentral Etemadi A, O’Doherty MG, Freedman ND, Hollenbeck AR, Dawsey SM, Abnet CC. A prospective cohort study of body size and risk of head and neck cancers in the NIH-AARP diet and health study. Cancer Epidemiol Biomarkers Prev. 2014;23(11):2422–9.PubMedPubMedCentral
99.
Zurück zum Zitat Gaudet MM, Olshan AF, Chuang SC, Berthiller J, Zhang ZF, Lissowska J, et al. Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Int J Epidemiol. 2010;39(4):1091–102.PubMedPubMedCentral Gaudet MM, Olshan AF, Chuang SC, Berthiller J, Zhang ZF, Lissowska J, et al. Body mass index and risk of head and neck cancer in a pooled analysis of case-control studies in the International Head and Neck Cancer Epidemiology (INHANCE) Consortium. Int J Epidemiol. 2010;39(4):1091–102.PubMedPubMedCentral
100.
Zurück zum Zitat • Ward, HA WPA, Muller DC, Steffen A, Johansson M, Norat T, et al. Measured adiposity in relation to head and neck cancer risk in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev. 2017;26(6):895–904. Study showing thatstrategies to reduce obesity may beneficially impact head and neck cancer incidence. • Ward, HA WPA, Muller DC, Steffen A, Johansson M, Norat T, et al. Measured adiposity in relation to head and neck cancer risk in the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev. 2017;26(6):895–904. Study showing thatstrategies to reduce obesity may beneficially impact head and neck cancer incidence.
Metadaten
Titel
Role of Obesity in Otorhinolaryngologic Diseases
verfasst von
Su Young Jung
Dong Choon Park
Sang Hoon Kim
Seung Geun Yeo
Publikationsdatum
01.07.2019
Verlag
Springer US
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 7/2019
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-019-0865-3

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