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Erschienen in: Current Infectious Disease Reports 3/2010

01.05.2010

Aspergillus Infections in the Head and Neck

verfasst von: Adrienne M. Laury, John M. DelGaudio

Erschienen in: Current Infectious Disease Reports | Ausgabe 3/2010

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Abstract

Aspergillus is a chronic colonizer as well as a nidus of infection in the sinuses and ears. In the sinuses, the severity of the disease is classified by the invasiveness of the infection. Invasive fungal sinusitis varies in its presentation based upon the infective organism and shows reduced morbidity if identified early, which requires a high index of suspicion. Allergic fungal sinusitis was recently further classified using a radiologic staging system and was proven to have symptomatic improvement with the concomitant use of surgery and immunotherapy. Finally, fungal ball appears to be a chronic problem that is usually cured with surgery. Aspergillus in the ear is a relatively common problem often related to prolonged antibiotic use and almost always successfully treated with topical antifungals.
Literatur
1.
Zurück zum Zitat Lackner A, Stammberger H, Buzina W, et al.: Fungi: a normal content of human nasal mucus. Am J Rhinol 2005, 19:125–129.PubMed Lackner A, Stammberger H, Buzina W, et al.: Fungi: a normal content of human nasal mucus. Am J Rhinol 2005, 19:125–129.PubMed
2.
Zurück zum Zitat Laskownick A, Kurdzielewica J, Macura A, Odrasinska-Cholewa B: Mycotic sinusitis in children. Mykosen. 1978, 21:407–411. Laskownick A, Kurdzielewica J, Macura A, Odrasinska-Cholewa B: Mycotic sinusitis in children. Mykosen. 1978, 21:407–411.
3.
Zurück zum Zitat De Shazo RD, O’Brien M, Chapin K, et al.: A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1987, 123:1181–1188. De Shazo RD, O’Brien M, Chapin K, et al.: A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1987, 123:1181–1188.
4.
Zurück zum Zitat Waitzman AA, Birt BD: Fungal sinusitis. J Otolaryngol 1994, 23:244–249.PubMed Waitzman AA, Birt BD: Fungal sinusitis. J Otolaryngol 1994, 23:244–249.PubMed
5.
Zurück zum Zitat Parikh SL, Venkatraman F, DelGaudio JM: Invasive fungal sinusitis: a 15 year review from a single institution. Am J Rhinol 2004, 18:75–81.PubMed Parikh SL, Venkatraman F, DelGaudio JM: Invasive fungal sinusitis: a 15 year review from a single institution. Am J Rhinol 2004, 18:75–81.PubMed
6.
Zurück zum Zitat • Ingley AP, Parikh SL, Delgaudio JM: Orbital and cranial nerve presentations and sequelae are hallmarks of invasive fungal sinusitis caused by Mucor in contrast to Aspergillus. Am J Rhinol 2008, 22:155–158. This article examines the increased morbid sequelae when IFS is caused by Mucor as opposed to Aspergillus.CrossRefPubMed • Ingley AP, Parikh SL, Delgaudio JM: Orbital and cranial nerve presentations and sequelae are hallmarks of invasive fungal sinusitis caused by Mucor in contrast to Aspergillus. Am J Rhinol 2008, 22:155–158. This article examines the increased morbid sequelae when IFS is caused by Mucor as opposed to Aspergillus.CrossRefPubMed
7.
Zurück zum Zitat • DelGaudio JM, Clemson LA: An early detection protocol for invasive fungal sinusitis in neutropenic patients successfully reduces extent of disease at presentation and long term morbidity. Laryngoscope 2008, 119:180–183. This article describes the components of an early detection protocol and its reduction in short- and long-term comorbidities related to IFS.CrossRef • DelGaudio JM, Clemson LA: An early detection protocol for invasive fungal sinusitis in neutropenic patients successfully reduces extent of disease at presentation and long term morbidity. Laryngoscope 2008, 119:180–183. This article describes the components of an early detection protocol and its reduction in short- and long-term comorbidities related to IFS.CrossRef
8.
Zurück zum Zitat DelGaudio JM, Swain RE, Kingdom TT, et al.: Computed tomographic findings in patients with invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 2003, 129:236–240.CrossRefPubMed DelGaudio JM, Swain RE, Kingdom TT, et al.: Computed tomographic findings in patients with invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 2003, 129:236–240.CrossRefPubMed
10.
Zurück zum Zitat Otto KJ, DelGaudio JM: Invasive fungal rhinosinusitis: what is the appropriate follow-up? Am J Rhinol 2006, 20:582–585.CrossRefPubMed Otto KJ, DelGaudio JM: Invasive fungal rhinosinusitis: what is the appropriate follow-up? Am J Rhinol 2006, 20:582–585.CrossRefPubMed
11.
Zurück zum Zitat Aribandi M, McCoy V, Bazan C: Imaging features of invasive and noninvasive fungal sinusitis: a review. Radiographics 2007, 27:1283–1296.CrossRefPubMed Aribandi M, McCoy V, Bazan C: Imaging features of invasive and noninvasive fungal sinusitis: a review. Radiographics 2007, 27:1283–1296.CrossRefPubMed
12.
Zurück zum Zitat Stringer SP, Ryan MW: Chronic invasive fungal rhinosinusitis. Otolaryngol Clin North Am 2000, 33:375–387.CrossRefPubMed Stringer SP, Ryan MW: Chronic invasive fungal rhinosinusitis. Otolaryngol Clin North Am 2000, 33:375–387.CrossRefPubMed
13.
Zurück zum Zitat Bent JP 3rd, Kuhn FA: Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg 1994, 111:580–588.CrossRefPubMed Bent JP 3rd, Kuhn FA: Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg 1994, 111:580–588.CrossRefPubMed
14.
Zurück zum Zitat Marfani MS, Jawaid MA, Shaikh SM, Thaheem K: Allergic fungal rhinosinusitis with skull base and orbital erosion. J Laryngol Otol 2009, 3:1–5. Marfani MS, Jawaid MA, Shaikh SM, Thaheem K: Allergic fungal rhinosinusitis with skull base and orbital erosion. J Laryngol Otol 2009, 3:1–5.
15.
Zurück zum Zitat Telmesani LM: Prevalence of allergic fungal sinusitis among patients with nasal polyps. Ann Saudi Med 2009, 29:212–214.PubMed Telmesani LM: Prevalence of allergic fungal sinusitis among patients with nasal polyps. Ann Saudi Med 2009, 29:212–214.PubMed
16.
Zurück zum Zitat Tritt S, McMains KC, Kountakis SE: Unilateral nasal polyposis: clinical presentation and pathology. Am J Otolaryngol 2008, 29:230–232.CrossRefPubMed Tritt S, McMains KC, Kountakis SE: Unilateral nasal polyposis: clinical presentation and pathology. Am J Otolaryngol 2008, 29:230–232.CrossRefPubMed
17.
Zurück zum Zitat Dhiwaker M, Thakar A, Bahadur S, et al.: Preoperative diagnosis of allergic fungal sinusitis. Laryngoscope 2003, 113:688–694.CrossRef Dhiwaker M, Thakar A, Bahadur S, et al.: Preoperative diagnosis of allergic fungal sinusitis. Laryngoscope 2003, 113:688–694.CrossRef
18.
Zurück zum Zitat Ferguson BJ, Barnes L, Bernstein JM, et al.: geographic variation in allergic fungal sinusitis. Otolaryngol Clin North Am 2000, 33:441–449.CrossRefPubMed Ferguson BJ, Barnes L, Bernstein JM, et al.: geographic variation in allergic fungal sinusitis. Otolaryngol Clin North Am 2000, 33:441–449.CrossRefPubMed
19.
Zurück zum Zitat Wise SK, Venkatraman G, Wise JC, DelGaudio JM: Ethnic and Gender Differences in Bone Erosion in Allergic Fungal Sinusitis. Am J Rhinol 2004, 19:397–405. Wise SK, Venkatraman G, Wise JC, DelGaudio JM: Ethnic and Gender Differences in Bone Erosion in Allergic Fungal Sinusitis. Am J Rhinol 2004, 19:397–405.
20.
Zurück zum Zitat • Wise SK, Rogers GA, Ghegan MD, et al.: Radiologic Staging System for Allergic Fungal Rhinosinusitis. J Otolaryngol Head Neck Surg 2009, 140:735–740. This article defines a radiologic staging system for AFRS in order to differentiate severity and possibly treatment in the future.CrossRef • Wise SK, Rogers GA, Ghegan MD, et al.: Radiologic Staging System for Allergic Fungal Rhinosinusitis. J Otolaryngol Head Neck Surg 2009, 140:735–740. This article defines a radiologic staging system for AFRS in order to differentiate severity and possibly treatment in the future.CrossRef
21.
Zurück zum Zitat Chang H, Han DH, Mo J, et al.: Early compliance and efficacy of sublingual immunotherapy in patients with allergic rhinitis for house dust mites. Clin Exp Otorhinolaryngol 2009, 2:136–140.CrossRefPubMed Chang H, Han DH, Mo J, et al.: Early compliance and efficacy of sublingual immunotherapy in patients with allergic rhinitis for house dust mites. Clin Exp Otorhinolaryngol 2009, 2:136–140.CrossRefPubMed
22.
Zurück zum Zitat Palma-Carlos AG, Santos AS, Branco-Ferreira M, et al.: Clinical efficacy and safety of preseasonal sublingual immunotherapy with grass pollen carbamylated allergoid in rhinitic patients. A double-blind, placebo-controlled study. Allergol Immunopathol (Madr) 2006, 34:194–198.CrossRef Palma-Carlos AG, Santos AS, Branco-Ferreira M, et al.: Clinical efficacy and safety of preseasonal sublingual immunotherapy with grass pollen carbamylated allergoid in rhinitic patients. A double-blind, placebo-controlled study. Allergol Immunopathol (Madr) 2006, 34:194–198.CrossRef
23.
Zurück zum Zitat Bassichis BA, Marple BF, Mabry RL, et al.: Use of immunotherapy in previously treated patients with allergic fungal sinusitis. Otolaryngol Head Neck Surg 2001, 125:487–490.PubMed Bassichis BA, Marple BF, Mabry RL, et al.: Use of immunotherapy in previously treated patients with allergic fungal sinusitis. Otolaryngol Head Neck Surg 2001, 125:487–490.PubMed
24.
Zurück zum Zitat Daudia A, Jones NS: Advances in management of paranasal sinus aspergillosis. J Laryngol Otol 2008, 122:331–335.CrossRefPubMed Daudia A, Jones NS: Advances in management of paranasal sinus aspergillosis. J Laryngol Otol 2008, 122:331–335.CrossRefPubMed
25.
Zurück zum Zitat Chan KO, Genowa KA, Javar AR: Effectiveness of itraconazole in the management of refractory allergic fungal rhinosinusitis. J Otolaryngol Head Neck Surg 2008, 37:870–874.PubMed Chan KO, Genowa KA, Javar AR: Effectiveness of itraconazole in the management of refractory allergic fungal rhinosinusitis. J Otolaryngol Head Neck Surg 2008, 37:870–874.PubMed
26.
Zurück zum Zitat deShazo RD, O’Brien M, Chapin K, et al.: Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 1997, 99:475–485.CrossRefPubMed deShazo RD, O’Brien M, Chapin K, et al.: Criteria for the diagnosis of sinus mycetoma. J Allergy Clin Immunol 1997, 99:475–485.CrossRefPubMed
27.
Zurück zum Zitat Dufour X, Kauffmann-Lacroix C, Ferrie JC, et al.: Paranasal sinus fungus ball and surgery: a review of 175 cases. Rhinology 2005, 43:34–39.PubMed Dufour X, Kauffmann-Lacroix C, Ferrie JC, et al.: Paranasal sinus fungus ball and surgery: a review of 175 cases. Rhinology 2005, 43:34–39.PubMed
28.
Zurück zum Zitat Nicolai P, Lombardi D, Tomenzoli D, et al.: Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. Laryngoscope 2009, 119:2275–2279.CrossRefPubMed Nicolai P, Lombardi D, Tomenzoli D, et al.: Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. Laryngoscope 2009, 119:2275–2279.CrossRefPubMed
29.
Zurück zum Zitat Mensi M, Salgarello S, Pinsi G, Piccioni M: Mycetoma of the maxillary sinus: endodontic and microbiological correlations. Oral Surg Oral Med Oral Path Oral Radiol Endod 2004, 98:119–123CrossRef Mensi M, Salgarello S, Pinsi G, Piccioni M: Mycetoma of the maxillary sinus: endodontic and microbiological correlations. Oral Surg Oral Med Oral Path Oral Radiol Endod 2004, 98:119–123CrossRef
30.
Zurück zum Zitat Klossek JM, Serrano E, Péloquin L, et al.: Functional endoscopic sinus surgery and mycetomas of the paranasal sinuses. Laryngoscope 1997, 107:112–117.CrossRefPubMed Klossek JM, Serrano E, Péloquin L, et al.: Functional endoscopic sinus surgery and mycetomas of the paranasal sinuses. Laryngoscope 1997, 107:112–117.CrossRefPubMed
31.
Zurück zum Zitat Dufour X, Kauffmann-Lacroix C, Ferrie JC, et al.: Paranasal sinus fungus ball: epidemiology, clinical features and diagnosis. A retrospective analysis of 173 cases from a single medical center in France, 1989–2002. Medical Mycol 2006, 44:61–67.CrossRef Dufour X, Kauffmann-Lacroix C, Ferrie JC, et al.: Paranasal sinus fungus ball: epidemiology, clinical features and diagnosis. A retrospective analysis of 173 cases from a single medical center in France, 1989–2002. Medical Mycol 2006, 44:61–67.CrossRef
32.
Zurück zum Zitat Mugliston T, O’Donoghue G: Otomycosis: a continuing problem. J Laryngol Otol 1985, 99:327–333.PubMed Mugliston T, O’Donoghue G: Otomycosis: a continuing problem. J Laryngol Otol 1985, 99:327–333.PubMed
33.
Zurück zum Zitat Vennewald I, Schonlebe J, Klemm E: Mycological and histological investigations in humans with middle ear infections. Mycoses 2003, 46:12–18.CrossRefPubMed Vennewald I, Schonlebe J, Klemm E: Mycological and histological investigations in humans with middle ear infections. Mycoses 2003, 46:12–18.CrossRefPubMed
34.
Zurück zum Zitat Ho T, Vrabec JT, Yoo D, Coker NJ: Otomycosis: Clinical features and treatment implications. Otolaryngol Head Neck Surg 2006, 135:787–791.CrossRefPubMed Ho T, Vrabec JT, Yoo D, Coker NJ: Otomycosis: Clinical features and treatment implications. Otolaryngol Head Neck Surg 2006, 135:787–791.CrossRefPubMed
35.
Zurück zum Zitat Del Palacio A, Cuetara MS, Lopez-Suso MJ, et al.: Randomized prospective comparative study: short-term treatment with ciclopiroxolamine (cream and solution) versus boric acid in the treatment of otomycosis. Mycoses 2002, 45:317–328.CrossRefPubMed Del Palacio A, Cuetara MS, Lopez-Suso MJ, et al.: Randomized prospective comparative study: short-term treatment with ciclopiroxolamine (cream and solution) versus boric acid in the treatment of otomycosis. Mycoses 2002, 45:317–328.CrossRefPubMed
Metadaten
Titel
Aspergillus Infections in the Head and Neck
verfasst von
Adrienne M. Laury
John M. DelGaudio
Publikationsdatum
01.05.2010
Verlag
Current Science Inc.
Erschienen in
Current Infectious Disease Reports / Ausgabe 3/2010
Print ISSN: 1523-3847
Elektronische ISSN: 1534-3146
DOI
https://doi.org/10.1007/s11908-010-0095-2

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