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Erschienen in: Indian Journal of Gastroenterology 5/2012

01.09.2012 | Short Report

Safety and efficacy of therapeutic endoscopic interventions in the management of biliary leak

verfasst von: Atul Sachdev, Jeet Ram Kashyap, Sanjay D’Cruz, Divyanshoo R. Kohli, Ram Singh, Kamal Singh

Erschienen in: Indian Journal of Gastroenterology | Ausgabe 5/2012

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Abstract

Endoscopic procedures which reduce the trans-papillary pressure gradient are the treatment of choice for management of biliary leaks. We analyzed the data of 102 patients with biliary leak managed by various endoscopic procedures like endoscopic sphincterotomy (ES), ES with stenting, stenting alone or nasobiliary drainage (NBD) alone; 90 of these patients had developed a leak after cholecystectomy. In the post-cholecystectomy group, cannulation was successful in 79 patients; therapeutic intervention was not possible in 14 of them due to complete transection of common bile duct in 6, and leak proximal to ligature in 8. In the remaining 65 patients, ES with stenting was done in 52, stent alone in 6, ES alone in 5 and NBD alone in 2. All 12 patients in other etiology group were treated with ES plus stenting. The leak closed in a mean of 3 (1–10) days in all patients. Stents were removed after 6–8 weeks. Endoscopic procedures are effective in managing biliary leaks.
Literatur
1.
Zurück zum Zitat Schlumpf R, Klotz HP, Wehrli H, Herzog U. A nation’s experience in laparoscopic cholecystectomy. Prospective multicenter analysis of 3722 cases. Surg Endosc. 1994;8:35–41.PubMedCrossRef Schlumpf R, Klotz HP, Wehrli H, Herzog U. A nation’s experience in laparoscopic cholecystectomy. Prospective multicenter analysis of 3722 cases. Surg Endosc. 1994;8:35–41.PubMedCrossRef
2.
Zurück zum Zitat Khan MH, Howard TJ, Fogel EL, et al. Frequency of biliary complications after laparoscopic cholecystectomy detected by ERCP: experience at a large tertiary referral center. Gastrointest Endosc. 2007;65:247–52.PubMedCrossRef Khan MH, Howard TJ, Fogel EL, et al. Frequency of biliary complications after laparoscopic cholecystectomy detected by ERCP: experience at a large tertiary referral center. Gastrointest Endosc. 2007;65:247–52.PubMedCrossRef
3.
Zurück zum Zitat Scott TR, Zucker KA, Bailey RW. Laparoscopic cholecystectomy: a review of 12,397 patients. Surg Laparosc Endosc. 1992;2:191–8.PubMed Scott TR, Zucker KA, Bailey RW. Laparoscopic cholecystectomy: a review of 12,397 patients. Surg Laparosc Endosc. 1992;2:191–8.PubMed
4.
Zurück zum Zitat Qin YS, Li ZS, Sun ZX, Wu RP, Wang N, Yao YZ. Endoscopic management of biliary complications after orthotopic liver transplantation. Hepatobiliary Pancreat Dis Int. 2006;5:39–42.PubMed Qin YS, Li ZS, Sun ZX, Wu RP, Wang N, Yao YZ. Endoscopic management of biliary complications after orthotopic liver transplantation. Hepatobiliary Pancreat Dis Int. 2006;5:39–42.PubMed
5.
Zurück zum Zitat Morgenstern L, McGrath MF, Carroll BJ, Paz-Partlow M, Berci G. Continuing hazards of the learning curve in laparoscopic cholecystectomy. Am Surg. 1995;61:914–8.PubMed Morgenstern L, McGrath MF, Carroll BJ, Paz-Partlow M, Berci G. Continuing hazards of the learning curve in laparoscopic cholecystectomy. Am Surg. 1995;61:914–8.PubMed
6.
Zurück zum Zitat Ryan ME, Geenen JE, Lehman GA, et al. Endoscopic intervention for biliary leaks after laparoscopic cholecystectomy: a multicenter review. Gastrointest Endosc. 1998;47:261–6.PubMedCrossRef Ryan ME, Geenen JE, Lehman GA, et al. Endoscopic intervention for biliary leaks after laparoscopic cholecystectomy: a multicenter review. Gastrointest Endosc. 1998;47:261–6.PubMedCrossRef
7.
Zurück zum Zitat Al Karawi MA, Sanai FM, Mohamed Ael S, Mohamed SA. Endoscopic management of postcholecystectomy bile duct injuries: review. Saudi J Gastroenterol. 2000;6:67–78.PubMed Al Karawi MA, Sanai FM, Mohamed Ael S, Mohamed SA. Endoscopic management of postcholecystectomy bile duct injuries: review. Saudi J Gastroenterol. 2000;6:67–78.PubMed
8.
Zurück zum Zitat Browder IW, Dowling JB, Koontz KK, Litwin MS. Early management of operative injuries of the extrahepatic biliary tract. Ann Surg. 1987;205:649–58.PubMedCrossRef Browder IW, Dowling JB, Koontz KK, Litwin MS. Early management of operative injuries of the extrahepatic biliary tract. Ann Surg. 1987;205:649–58.PubMedCrossRef
9.
Zurück zum Zitat Lillemoe KD. Benign post-operative bile duct strictures. Baillieres Clin Gastroenterol. 1997;11:749–79.PubMedCrossRef Lillemoe KD. Benign post-operative bile duct strictures. Baillieres Clin Gastroenterol. 1997;11:749–79.PubMedCrossRef
10.
Zurück zum Zitat Bridges A, Wilcox CM, Varadarajulu S. Endoscopic management of traumatic bile leaks. Gastrointest Endosc. 2007;65:1081–5.PubMedCrossRef Bridges A, Wilcox CM, Varadarajulu S. Endoscopic management of traumatic bile leaks. Gastrointest Endosc. 2007;65:1081–5.PubMedCrossRef
11.
Zurück zum Zitat Shah JN. Endoscopic treatment of bile leaks: current standards and recent innovations. Gastrointest Endosc. 2007;65:1069–72.PubMedCrossRef Shah JN. Endoscopic treatment of bile leaks: current standards and recent innovations. Gastrointest Endosc. 2007;65:1069–72.PubMedCrossRef
12.
Zurück zum Zitat Pawa S, Al-Kawas FH. ERCP in the management of biliary complications after cholecystectomy. Curr Gastroenterol Rep. 2009;11:160–6.PubMedCrossRef Pawa S, Al-Kawas FH. ERCP in the management of biliary complications after cholecystectomy. Curr Gastroenterol Rep. 2009;11:160–6.PubMedCrossRef
13.
Zurück zum Zitat Donnellan F, Zeb F, Courtney G, Aftab AR. Successful outcome of sphincterotomy and 7 French pigtail stent insertion in the management of post-cholecystectomy bile leaks. Hepatobiliary Pancreat Dis Int. 2009;8:309–11.PubMed Donnellan F, Zeb F, Courtney G, Aftab AR. Successful outcome of sphincterotomy and 7 French pigtail stent insertion in the management of post-cholecystectomy bile leaks. Hepatobiliary Pancreat Dis Int. 2009;8:309–11.PubMed
14.
Zurück zum Zitat Katsinelos P, Kountouras J, Paroutoglou G, et al. A comparative study of 10-Fr vs. 7-Fr straight plastic stents in the treatment of postcholecystectomy bile leak. Surg Endosc. 2008;22:101–6.PubMedCrossRef Katsinelos P, Kountouras J, Paroutoglou G, et al. A comparative study of 10-Fr vs. 7-Fr straight plastic stents in the treatment of postcholecystectomy bile leak. Surg Endosc. 2008;22:101–6.PubMedCrossRef
15.
Zurück zum Zitat Kaffes AJ, Hourigan L, De Luca N, Byth K, Williams SJ, Bourke MJ. Impact of endoscopic intervention in 100 patients with suspected postcholecystectomy bile leak. Gastrointest Endosc. 2005;61:269–75.PubMedCrossRef Kaffes AJ, Hourigan L, De Luca N, Byth K, Williams SJ, Bourke MJ. Impact of endoscopic intervention in 100 patients with suspected postcholecystectomy bile leak. Gastrointest Endosc. 2005;61:269–75.PubMedCrossRef
16.
Zurück zum Zitat Mavrogiannis C, Liatsos C, Papanikolaou IS, Karagiannis S, Galanis P, Romanos A. Biliary stenting alone versus biliary stenting plus sphincterotomy for the treatment of post-laparoscopic cholecystectomy biliary leaks: a prospective randomized study. Eur J Gastroenterol Hepatol. 2006;18:405–9.PubMedCrossRef Mavrogiannis C, Liatsos C, Papanikolaou IS, Karagiannis S, Galanis P, Romanos A. Biliary stenting alone versus biliary stenting plus sphincterotomy for the treatment of post-laparoscopic cholecystectomy biliary leaks: a prospective randomized study. Eur J Gastroenterol Hepatol. 2006;18:405–9.PubMedCrossRef
17.
Zurück zum Zitat Agarwal N, Sharma BC, Garg S, Kumar R, Sarin SK. Endoscopic management of postoperative bile leaks. Hepatobiliary Pancreat Dis Int. 2006;5:273–7.PubMed Agarwal N, Sharma BC, Garg S, Kumar R, Sarin SK. Endoscopic management of postoperative bile leaks. Hepatobiliary Pancreat Dis Int. 2006;5:273–7.PubMed
18.
Zurück zum Zitat Pinkas H, Brady PG. Biliary leaks after laparoscopic cholecystectomy: time to stent or time to drain. Hepatobiliary Pancreat Dis Int. 2008;7:628–32.PubMed Pinkas H, Brady PG. Biliary leaks after laparoscopic cholecystectomy: time to stent or time to drain. Hepatobiliary Pancreat Dis Int. 2008;7:628–32.PubMed
19.
Zurück zum Zitat Cote GA, Ansstas M, Shah S, et al. Findings at endoscopic retrograde cholangiopancreatography after endoscopic treatment of postcholecystectomy bile leaks. Surg Endosc. 2010;24:1752–6.PubMedCrossRef Cote GA, Ansstas M, Shah S, et al. Findings at endoscopic retrograde cholangiopancreatography after endoscopic treatment of postcholecystectomy bile leaks. Surg Endosc. 2010;24:1752–6.PubMedCrossRef
20.
Zurück zum Zitat Salih M, Hamid S, Shah HA, Abbas Z, Jafri W. Endoscopic management of biliary leaks after open and laparoscopic cholecystectomy. J Pak Med Assoc. 2007;57:117–9.PubMed Salih M, Hamid S, Shah HA, Abbas Z, Jafri W. Endoscopic management of biliary leaks after open and laparoscopic cholecystectomy. J Pak Med Assoc. 2007;57:117–9.PubMed
21.
Zurück zum Zitat Sandha GS, Bourke MJ, Haber GB, Kortan PP. Endoscopic therapy for bile leak based on a new classification: results in 207 patients. Gastrointest Endosc. 2004;4:567–74.CrossRef Sandha GS, Bourke MJ, Haber GB, Kortan PP. Endoscopic therapy for bile leak based on a new classification: results in 207 patients. Gastrointest Endosc. 2004;4:567–74.CrossRef
22.
Zurück zum Zitat Freeman ML, Nelson DB, Sherman S, et al. Complications of endoscopic biliary sphincterotomy. N Engl J Med. 1996;335:909–18.PubMedCrossRef Freeman ML, Nelson DB, Sherman S, et al. Complications of endoscopic biliary sphincterotomy. N Engl J Med. 1996;335:909–18.PubMedCrossRef
23.
Zurück zum Zitat Freeman ML. Complications of endoscopic sphincterotomy. Endoscopy. 1998;30:A216–20. Freeman ML. Complications of endoscopic sphincterotomy. Endoscopy. 1998;30:A216–20.
Metadaten
Titel
Safety and efficacy of therapeutic endoscopic interventions in the management of biliary leak
verfasst von
Atul Sachdev
Jeet Ram Kashyap
Sanjay D’Cruz
Divyanshoo R. Kohli
Ram Singh
Kamal Singh
Publikationsdatum
01.09.2012
Verlag
Springer-Verlag
Erschienen in
Indian Journal of Gastroenterology / Ausgabe 5/2012
Print ISSN: 0254-8860
Elektronische ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-012-0209-x

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