Skip to main content
Erschienen in: Journal of Endocrinological Investigation 5/2016

01.05.2016 | Original Article

Branchial cleft and pouch anomalies in childhood: a report of 50 surgical cases

verfasst von: C. Spinelli, L. Rossi, S. Strambi, J. Piscioneri, G. Natale, A. Bertocchini, A. Messineo

Erschienen in: Journal of Endocrinological Investigation | Ausgabe 5/2016

Einloggen, um Zugang zu erhalten

Abstract

Background and aims

Branchial abnormalities occur when there is disturbance in the maturation of the branchial apparatus during fetal development. Branchial anomalies are congenital lesions usually present in childhood, even if they can be diagnosed later for enlargement or infection. A correct diagnosis will lead to proper management: complete surgical excision is the treatment of choice. The purpose of this article is to present clinical features, diagnostic methods and surgical treatment of branchial anomalies in childhood, based on a series of 50 patients.

Methods

We conducted a retrospective analysis of a total of 50 pediatric patients operated from June 2005 to June 2014 for the presence of branchial cleft anomalies.

Results

27 cases (54 %) presented a second branchial cleft fistula and 11 cases (22 %) a second branchial cleft cyst and one case (2 %) presented both cyst and sinus of the second branchial cleft; four cases (8 %) presented first branchial cleft cyst whereas four cases (8 %) a first branchial cleft sinus and two cases (4 %) a first branchial cleft fistula; one case (2 %) presented a piriform sinus fistula (third branchial cleft). None of our patients presented anomalies of the fourth branchial cleft. All patients underwent surgical treatment and lesions have been removed by excision or fistulectomy. No post-surgical complication occurred. The rate of recurrence was 4 %.

Conclusions

Pre-operative diagnosis supplies important information to the surgeon for a proper therapy: a complete excision of the lesion without inflammatory signs is essential to avoid re-intervention and to achieve a good outcome.
Literatur
1.
Zurück zum Zitat Shrime M, Kacker A, Bent J et al (2003) Fourth branchial complex anomalies: a case series. Int J Pediatr Otorhinolaryngol 67(11):1227–1233CrossRefPubMed Shrime M, Kacker A, Bent J et al (2003) Fourth branchial complex anomalies: a case series. Int J Pediatr Otorhinolaryngol 67(11):1227–1233CrossRefPubMed
2.
Zurück zum Zitat Pereira KD, Losh GG, Oliver D et al (2004) Management of anomalies of the third and fourth branchial pouches. Int J Pediatr Otorhinolaryngol 68(1):43–50CrossRefPubMed Pereira KD, Losh GG, Oliver D et al (2004) Management of anomalies of the third and fourth branchial pouches. Int J Pediatr Otorhinolaryngol 68(1):43–50CrossRefPubMed
3.
Zurück zum Zitat Joice P, Sudarshan T, Hussain SS (2012) First branchial arch abnormality: diagnostic dilemma and excision with facial nerve preservation. J Laryngol Otol 126(9):918–922CrossRefPubMed Joice P, Sudarshan T, Hussain SS (2012) First branchial arch abnormality: diagnostic dilemma and excision with facial nerve preservation. J Laryngol Otol 126(9):918–922CrossRefPubMed
4.
Zurück zum Zitat Luschka H (1848) Ueber fistula colli congenital. Archiv fur Physiologische Heilkunde. 7:25–27 Luschka H (1848) Ueber fistula colli congenital. Archiv fur Physiologische Heilkunde. 7:25–27
5.
Zurück zum Zitat Wenglowski R (1912) Ueber die Halsfisteln und Cysten. Langenbeck. Arhiv fur Klinische Chirurgie 98:151–208 Wenglowski R (1912) Ueber die Halsfisteln und Cysten. Langenbeck. Arhiv fur Klinische Chirurgie 98:151–208
6.
7.
Zurück zum Zitat Choi SS, Zaltal GH (1995) Branchial anomalies: a review of 52 cases. Laryngoscope 105:909–913CrossRefPubMed Choi SS, Zaltal GH (1995) Branchial anomalies: a review of 52 cases. Laryngoscope 105:909–913CrossRefPubMed
8.
Zurück zum Zitat Bajaj Y, Ifeacho S, Tweedie D et al (2011) Branchial anomalies in children. Int J Pediatr Otorhinolaryngol 75(8):1020–1023CrossRefPubMed Bajaj Y, Ifeacho S, Tweedie D et al (2011) Branchial anomalies in children. Int J Pediatr Otorhinolaryngol 75(8):1020–1023CrossRefPubMed
9.
Zurück zum Zitat Maran AGD, Buckanan DR (1978) Branchial cysts, sinuses and fistulae. Clin Otolaryngol 3:77–92CrossRefPubMed Maran AGD, Buckanan DR (1978) Branchial cysts, sinuses and fistulae. Clin Otolaryngol 3:77–92CrossRefPubMed
10.
Zurück zum Zitat Nicoucar K, Giger R, Jaecklin T et al (2010) Management of congenital third branchial arch anomalies: a systematic review. Otolaryngol Head Neck Surg 142(1):21–28.e2 Nicoucar K, Giger R, Jaecklin T et al (2010) Management of congenital third branchial arch anomalies: a systematic review. Otolaryngol Head Neck Surg 142(1):21–28.e2
11.
Zurück zum Zitat Zaifullah S, Yunus MR, See GB (2013) Diagnosis and treatment of branchial cleft anomalies in UKMMC: a 10-year retrospective study. Eur Arch Otorhinolaryngol 270(4):1501–1506CrossRefPubMed Zaifullah S, Yunus MR, See GB (2013) Diagnosis and treatment of branchial cleft anomalies in UKMMC: a 10-year retrospective study. Eur Arch Otorhinolaryngol 270(4):1501–1506CrossRefPubMed
12.
Zurück zum Zitat Papadogeorgakis N, Petsinis V, Parara E et al (2009) Branchial cleft cysts in adults. Diagnostic procedures and treatment in a series of 18 cases. Oral Maxillofac Surg. 13(2):79–85CrossRefPubMed Papadogeorgakis N, Petsinis V, Parara E et al (2009) Branchial cleft cysts in adults. Diagnostic procedures and treatment in a series of 18 cases. Oral Maxillofac Surg. 13(2):79–85CrossRefPubMed
13.
Zurück zum Zitat Chen PS, Lin YC, Lin YS (2012) Nasopharyngeal branchial cleft cyst. J Chin Med Assoc 75(12):660–662CrossRefPubMed Chen PS, Lin YC, Lin YS (2012) Nasopharyngeal branchial cleft cyst. J Chin Med Assoc 75(12):660–662CrossRefPubMed
14.
15.
Zurück zum Zitat Work WP (1972) Newer concepts of first branchial cleft defects. Laryngoscope 82(9):1581–1593CrossRefPubMed Work WP (1972) Newer concepts of first branchial cleft defects. Laryngoscope 82(9):1581–1593CrossRefPubMed
16.
Zurück zum Zitat Olsen KD, Maragos NE, Weiland LH (1980) First branchial cleft anomalies. Laryngoscope 90(3):423–436CrossRefPubMed Olsen KD, Maragos NE, Weiland LH (1980) First branchial cleft anomalies. Laryngoscope 90(3):423–436CrossRefPubMed
17.
Zurück zum Zitat Magdy EA, Ashram YA (2013) First branchial cleft anomalies: presentation, variability and safe surgical management. Eur Arch Otorhinolaryngol 270(6):1917–1925CrossRefPubMed Magdy EA, Ashram YA (2013) First branchial cleft anomalies: presentation, variability and safe surgical management. Eur Arch Otorhinolaryngol 270(6):1917–1925CrossRefPubMed
18.
Zurück zum Zitat Arnot RS (1971) Defects of the first branchial cleft. South African J Surg 9:93–99 Arnot RS (1971) Defects of the first branchial cleft. South African J Surg 9:93–99
19.
Zurück zum Zitat Franciosi JP, Sell LL, Conley SF et al (2002) Pyriform sinus malformations: a cadaveric representation. J Pediatr Surg 37(3):533–538CrossRefPubMed Franciosi JP, Sell LL, Conley SF et al (2002) Pyriform sinus malformations: a cadaveric representation. J Pediatr Surg 37(3):533–538CrossRefPubMed
20.
Zurück zum Zitat Nathan K, Bajaj Y, Jephson CG (2012) Stridor as a presentation of fourth branchial pouch sinus. J Laryngol Otol 126(4):432–434CrossRefPubMed Nathan K, Bajaj Y, Jephson CG (2012) Stridor as a presentation of fourth branchial pouch sinus. J Laryngol Otol 126(4):432–434CrossRefPubMed
23.
Zurück zum Zitat Shankar VG, Babu TA, Swami HB (2012) A rare case of complete second arch branchial fistula in a 7-year-old child. Natl J Maxillofac Surg 3(2):226–228CrossRefPubMedPubMedCentral Shankar VG, Babu TA, Swami HB (2012) A rare case of complete second arch branchial fistula in a 7-year-old child. Natl J Maxillofac Surg 3(2):226–228CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat D’Souza AR, Uppal HS, De R et al (2002) Updating concepts of first branchial cleft defects: a literature review. Int J Pediatr Otorhinolaryngol 62:103–109CrossRefPubMed D’Souza AR, Uppal HS, De R et al (2002) Updating concepts of first branchial cleft defects: a literature review. Int J Pediatr Otorhinolaryngol 62:103–109CrossRefPubMed
25.
Zurück zum Zitat Yalçin S, Karlidağ T, Kaygusuz I et al (2003) First branchial cleft sinus presenting with cholesteatoma and external auditory canal atresia. Int J Pediatr Otorhinolaryngol 67(7):811–814CrossRefPubMed Yalçin S, Karlidağ T, Kaygusuz I et al (2003) First branchial cleft sinus presenting with cholesteatoma and external auditory canal atresia. Int J Pediatr Otorhinolaryngol 67(7):811–814CrossRefPubMed
26.
Zurück zum Zitat Lambert PR, Dodson EE (1996) Congenital malformations of the external auditory canal. Otolaryngol Clin North Am 29(5):741–760PubMed Lambert PR, Dodson EE (1996) Congenital malformations of the external auditory canal. Otolaryngol Clin North Am 29(5):741–760PubMed
27.
Zurück zum Zitat Abdollahi Fakhim S, Naderpoor M, Mousaviagdas M (2014) First branchial cleft fistula associated with external auditory canal stenosis and middle ear cholesteatoma. Iran J Otorhinolaryngol 26(77):263–266 Abdollahi Fakhim S, Naderpoor M, Mousaviagdas M (2014) First branchial cleft fistula associated with external auditory canal stenosis and middle ear cholesteatoma. Iran J Otorhinolaryngol 26(77):263–266
28.
Zurück zum Zitat Kumar R, Sikka K, Sagar P et al (2013) First branchial cleft anomalies: avoiding the misdiagnosis. Indian J Otolaryngol Head Neck Surg. 65(3):260–263CrossRefPubMedPubMedCentral Kumar R, Sikka K, Sagar P et al (2013) First branchial cleft anomalies: avoiding the misdiagnosis. Indian J Otolaryngol Head Neck Surg. 65(3):260–263CrossRefPubMedPubMedCentral
29.
Zurück zum Zitat Can IH, Doğan S, Dönmez M et al (2012) A different type of branchial fistula as part of a branchiootorenal syndrome. J Pediatr Surg 47(2):404–407CrossRefPubMed Can IH, Doğan S, Dönmez M et al (2012) A different type of branchial fistula as part of a branchiootorenal syndrome. J Pediatr Surg 47(2):404–407CrossRefPubMed
30.
Zurück zum Zitat Teng Y, Wang H, Xu R et al (2012) Primary branchiogenic carcinoma in the first branchial cleft of a child. Oncol Lett. 4(6):1371–1373 [Epub 2012 Sep 12] PubMedPubMedCentral Teng Y, Wang H, Xu R et al (2012) Primary branchiogenic carcinoma in the first branchial cleft of a child. Oncol Lett. 4(6):1371–1373 [Epub 2012 Sep 12] PubMedPubMedCentral
31.
Zurück zum Zitat Cain RB, Kasznica P, Brundage WJ (2012) Right-sided pyriform sinus fistula: a case report and review of the literature. Case Rep Otolaryngol 2012:934968PubMedPubMedCentral Cain RB, Kasznica P, Brundage WJ (2012) Right-sided pyriform sinus fistula: a case report and review of the literature. Case Rep Otolaryngol 2012:934968PubMedPubMedCentral
32.
Zurück zum Zitat Shino M, Yasuoka Y, Nakajima K et al (2014) A case of pyriform sinus fistula infection with double tracts. Case Rep Otolaryngol 2014:126840PubMedPubMedCentral Shino M, Yasuoka Y, Nakajima K et al (2014) A case of pyriform sinus fistula infection with double tracts. Case Rep Otolaryngol 2014:126840PubMedPubMedCentral
33.
Zurück zum Zitat Sun Z, Fu K, Zhang Z et al (2012) Multidetector computerized tomographic fistulography in the evaluation of congenital branchial cleft fistulae and sinuses. Oral Surg Oral Med Oral Pathol Oral Radiol 113(5):688–694CrossRefPubMed Sun Z, Fu K, Zhang Z et al (2012) Multidetector computerized tomographic fistulography in the evaluation of congenital branchial cleft fistulae and sinuses. Oral Surg Oral Med Oral Pathol Oral Radiol 113(5):688–694CrossRefPubMed
34.
36.
Zurück zum Zitat Panchbhai AS, Choudhary MS (2012) Branchial cleft cyst at an unusual location: a rare case with a brief review. Dentomaxillofac Radiol 41(8):696–702CrossRefPubMedPubMedCentral Panchbhai AS, Choudhary MS (2012) Branchial cleft cyst at an unusual location: a rare case with a brief review. Dentomaxillofac Radiol 41(8):696–702CrossRefPubMedPubMedCentral
37.
Zurück zum Zitat Guarisco JL, Fatakia A (2008) Intraoperative fistulograms in the management of branchial apparatus abnormalities in children. Int J Pediatr Otorhinolaryngol 72:1777–1782CrossRefPubMed Guarisco JL, Fatakia A (2008) Intraoperative fistulograms in the management of branchial apparatus abnormalities in children. Int J Pediatr Otorhinolaryngol 72:1777–1782CrossRefPubMed
38.
Zurück zum Zitat Liberman M, Kay S, Emil S et al (2002) Ten years of experience with third and fourth branchial remnants. J Pediatr Surg 37(5):685–690CrossRefPubMed Liberman M, Kay S, Emil S et al (2002) Ten years of experience with third and fourth branchial remnants. J Pediatr Surg 37(5):685–690CrossRefPubMed
39.
Zurück zum Zitat Guo YX, Guo CB (2012) Relation between a first branchial cleft anomaly and the facial nerve. Br J Oral Maxillofac Surg 50(3):259–263CrossRefPubMed Guo YX, Guo CB (2012) Relation between a first branchial cleft anomaly and the facial nerve. Br J Oral Maxillofac Surg 50(3):259–263CrossRefPubMed
40.
Zurück zum Zitat Liu Y, Li T, Xue J et al (2012) First branchial cleft fistula presenting with internal opening on the Eustachian tube: illustrated cases and literature review. Int J Pediatr Otorhinolaryngol 76(5):642–645CrossRefPubMed Liu Y, Li T, Xue J et al (2012) First branchial cleft fistula presenting with internal opening on the Eustachian tube: illustrated cases and literature review. Int J Pediatr Otorhinolaryngol 76(5):642–645CrossRefPubMed
41.
Zurück zum Zitat Waldhausen JH (2006) Branchial cleft and arch anomalies in children. Semin Pediatr Surg 15(2):64–69CrossRefPubMed Waldhausen JH (2006) Branchial cleft and arch anomalies in children. Semin Pediatr Surg 15(2):64–69CrossRefPubMed
42.
Zurück zum Zitat Chen J, Chen W, Zhang J et al (2014) Endoscope-assisted second branchial cleft cyst resection via an incision along skin line on lateral neck. Eur Arch Otorhinolaryngol 271(10):2789–2793CrossRefPubMed Chen J, Chen W, Zhang J et al (2014) Endoscope-assisted second branchial cleft cyst resection via an incision along skin line on lateral neck. Eur Arch Otorhinolaryngol 271(10):2789–2793CrossRefPubMed
43.
Zurück zum Zitat Kajosaari L, Mäkitie A, Salminen P et al (2014) Second branchial cleft fistulae: patient characteristics and surgical outcome. Int J Pediatr Otorhinolaryngol 78(9):1503–1507CrossRefPubMed Kajosaari L, Mäkitie A, Salminen P et al (2014) Second branchial cleft fistulae: patient characteristics and surgical outcome. Int J Pediatr Otorhinolaryngol 78(9):1503–1507CrossRefPubMed
44.
Zurück zum Zitat Mou JW, Chan KW, Wong YS et al (2014) Recurrent deep neck abscess and piriform sinus tract: a 15-year review on the diagnosis and management. J Pediatr Surg 49(8):1264–1267CrossRefPubMed Mou JW, Chan KW, Wong YS et al (2014) Recurrent deep neck abscess and piriform sinus tract: a 15-year review on the diagnosis and management. J Pediatr Surg 49(8):1264–1267CrossRefPubMed
45.
Zurück zum Zitat Ahmed J, De S, Hore ID, Bailey CM et al (2008) Treatment of piriform fossa sinuses with monopolar diathermy. J Laryngol Otol 122(8):840–844 Epub 2007 Aug 1 CrossRefPubMed Ahmed J, De S, Hore ID, Bailey CM et al (2008) Treatment of piriform fossa sinuses with monopolar diathermy. J Laryngol Otol 122(8):840–844 Epub 2007 Aug 1 CrossRefPubMed
46.
Zurück zum Zitat Wong PY, Moore A, Daya H (2014) Management of third branchial pouch anomalies—an evolution of a minimally invasive technique. Int J Pediatr Otorhinolaryngol 78(3):493–498CrossRefPubMed Wong PY, Moore A, Daya H (2014) Management of third branchial pouch anomalies—an evolution of a minimally invasive technique. Int J Pediatr Otorhinolaryngol 78(3):493–498CrossRefPubMed
47.
Zurück zum Zitat Kim MG, Lee NH, Ban JH et al (2009) Sclerotherapy of branchial cleft cysts using OK-432. Otolaryngol Head Neck Surg 141(3):329–334CrossRefPubMed Kim MG, Lee NH, Ban JH et al (2009) Sclerotherapy of branchial cleft cysts using OK-432. Otolaryngol Head Neck Surg 141(3):329–334CrossRefPubMed
48.
Zurück zum Zitat Agaton-Bonilla FC, Gay-Escoda C (1996) Diagnosis and treatment of branchial cleft cysts and fistulae. A retrospective study of 183 patients. Int J Oral Maxillofac Surg 25(6):449–452CrossRefPubMed Agaton-Bonilla FC, Gay-Escoda C (1996) Diagnosis and treatment of branchial cleft cysts and fistulae. A retrospective study of 183 patients. Int J Oral Maxillofac Surg 25(6):449–452CrossRefPubMed
Metadaten
Titel
Branchial cleft and pouch anomalies in childhood: a report of 50 surgical cases
verfasst von
C. Spinelli
L. Rossi
S. Strambi
J. Piscioneri
G. Natale
A. Bertocchini
A. Messineo
Publikationsdatum
01.05.2016
Verlag
Springer International Publishing
Erschienen in
Journal of Endocrinological Investigation / Ausgabe 5/2016
Elektronische ISSN: 1720-8386
DOI
https://doi.org/10.1007/s40618-015-0390-8

Weitere Artikel der Ausgabe 5/2016

Journal of Endocrinological Investigation 5/2016 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

Nach Herzinfarkt mit Typ-1-Diabetes schlechtere Karten als mit Typ 2?

29.05.2024 Herzinfarkt Nachrichten

Bei Menschen mit Typ-2-Diabetes sind die Chancen, einen Myokardinfarkt zu überleben, in den letzten 15 Jahren deutlich gestiegen – nicht jedoch bei Betroffenen mit Typ 1.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Costims – das nächste heiße Ding in der Krebstherapie?

28.05.2024 Onkologische Immuntherapie Nachrichten

„Kalte“ Tumoren werden heiß – CD28-kostimulatorische Antikörper sollen dies ermöglichen. Am besten könnten diese in Kombination mit BiTEs und Checkpointhemmern wirken. Erste klinische Studien laufen bereits.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.