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Intensive Care Medicine

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20.08.2016 | Understanding the Disease

Cardiac dysfunction in sepsis

verfasst von: Anders Aneman, Antoine Vieillard-Baron

Erschienen in: Intensive Care Medicine | Ausgabe 12/2016

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Excerpt

The incidence of cardiac dysfunction in septic shock, septic cardiomyopathy, is between 40 and 60 % as diagnosed within the first 3 days [1]. Its recognition, treatment and focus for clinical research are hampered by the lack of a consensus definition. An acute or acute-on-chronic but reversible ventricular dysfunction, typically visualized at echocardiography, is generally agreed upon. The systemic nature of sepsis and the interdependence of the left (LV) and right (RV) ventricles mean that heart function is affected globally. …

Vieillard-Baron A, Caille V, Charron C, Belliard G, Page B, Jardin F (2008) Actual incidence of global left ventricular hypokinesia in adult septic shock. Crit Care Med 36:1701–1706CrossRefPubMed

Teboul JL, Saugel B, Cecconi M, De Backer D, Hofer CK, Monnet X, Perel A, Pinsky, Reuter DA, Rhodes A, Squara P, Vincent JL, Scheeren TW (2016) Less invasive hemodynamic monitoring in critically ill patients. Intensive Care Med. doi:10.1007/s00134-016-4375-7

Cecconi M, De Backer D, Antonelli M, Beale R, Bakker J, Hofer C, Jaeschke R, Mebazaa A, Pinsky MR, Teboul JL, Vincent JL, Rhodes A (2014) Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med 40:1795–1815CrossRefPubMedPubMedCentral

Bull TM, Clark B, McFann K, Moss M, National Institutes of Health, National Heart, Lung, and Blood Institute ARDS Network (2010) Pulmonary vascular dysfunction is associated with poor outcomes in patients with acute lung injury. Am J Repsir Crit Care Med 182:1123–1128CrossRef

Vieillard-Baron A, Matthay M, Teboul JL, Bein T, Schultz M, Magder S, Marini JJ (2016) Experts’ opinion on management of hemodynamics in ARDS patients: focus on the effects of mechanical ventilation. Intensive Care Med 42:739–749CrossRefPubMed

Huang SJ, Nalos M, McLean AS (2013) Is early ventricular dysfunction or dilatation associated with lower mortality rate in adult severe sepsis and septic shock? A meta-analysis. Crit Care 17:R96. doi:10.1186/cc12741 CrossRefPubMedPubMedCentral

Chang WT, Lee WH, Lee WT, Chen PS, Su YR, Liu PY, Liu YW, Tsai WC (2015) Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients. Intensive Care Med 41:1791–1799CrossRefPubMed

Gonzalez C, Begot E, Dalmay F, Pichon N, François B, Fedou AL, Chapellas C, Galy A, Mancia C, Daix T, Vignon P (2016) Prognostic impact of left ventricular diastolic function in patients with septic shock. Ann Intensive Care 6:36. doi:10.1186/s13613-016-0136-6 CrossRefPubMedPubMedCentral

Landesberg G, Gilon D, Meroz Y, Georgieva M, Levin PD, Goodman S et al (2012) Diastolic dysfunction and mortality in severe sepsis and septic shock. Eur Heart J 33:895–903CrossRefPubMed

10.

Orde SR, Pulido JN, Masaki M, Gillespie S, Spoon JN, Kane GC, Oh JK (2014) Outcome prediction in sepsis: speckle tracking echocardiography based assessment of myocardial function. Crit Care 18:R149. doi:10.1186/cc13987 CrossRefPubMedPubMedCentral

11.

Zangrillo A, Putzu A, Monaco F, Oriani A, Frau G, De Luca M, Di Tomasso N, Bignami E, Lomivorotov V, Likhvantsev V, Landoni G (2015) Levosimendan reduces mortality in patients with severe sepsis and septic shock: a meta-analysis of randomized trials. J Crit Care 30:908–913CrossRefPubMed

12.

Orme RM, Perkins GD, McAuley DF, Liu KD, Mason AJ, Morelli A, Singer M, Ashby D, Gordon AC (2014) An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial. Trials 15:199. doi:10.1186/1745-6215-15-199 CrossRefPubMedPubMedCentral

13.

Vieillard Baron A, Schmitt JM, Beauchet A, Augarde R, Prin S, Page B, Jardin F (2001) Early preload adaptation in septic shock? A transesophageal echocardiographic study. Anesthesiology 94:400–406CrossRefPubMed

14.

Asfar P, Russell JA, Tuckermann J, Radermacher P (2016) Selepressin in septic shock: a step toward decatecholaminization? Crit Care Med 44:234–236CrossRefPubMed

15.

Morelli A, Singer M, Ranieri VM, D’Egidio A, Mascia L, Orecchioni A, Piscioneri F, Guarracino F, Greco E, Peruzzi M, Biondi-Zoccai G, Frati G, Romano SM (2016) Heart rate reduction with esmolol is associated with improved arterial elastance in patients with septic shock: a prospective observational study. Intensive Care Med. doi:10.1007/s00134-016-4351-2

Titel: Cardiac dysfunction in sepsis
verfasst von: Anders Aneman
Antoine Vieillard-Baron
Publikationsdatum: 20.08.2016
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 12/2016
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-016-4503-4

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