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Knee Surgery, Sports Traumatology, Arthroscopy

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01.08.2011 | Knee

The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments

verfasst von: Jan Philipp Benthien, Peter Behrens

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 8/2011

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Abstract

Purpose

Articular resurfacing by treatment of chondral defects may include chondral abrasion, autologous chondrocyte Implantation (ACI), matrix-induced chondrocyte transplantation (MACT) or osteochondral autologous transplantation (OATS). This technical note describes the method of autologous matrix-induced chondrogenesis (AMIC), a one-step procedure combining subchondral microfracture with the fixation of a collagen I/III membrane with fibrin glue or sutures.

Methods

This is a technical note on the AMIC procedure and its further development.

Results and conclusion

This method is applied primarily in chondral or osteochondral lesions of the knee. Indications and contraindications are provided; the technique is described. The further development of AMIC is described with an increased focus on the subchondral zone and the complex of cartilage and bone, the osteochondral unit, which receives increased attention in cartilage research.

Level of evidence

IV.

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Titel: The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments
verfasst von: Jan Philipp Benthien
Peter Behrens
Publikationsdatum: 01.08.2011
Verlag: Springer-Verlag
Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 8/2011
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI: https://doi.org/10.1007/s00167-010-1356-1

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Springer Medizin

The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments

Abstract

Purpose

Methods

Results and conclusion

Level of evidence

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Update Orthopädie und Unfallchirurgie

Springer Medizin

Abstract

Purpose

Methods

Results and conclusion

Level of evidence

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