Introduction
Methods
Measurements
Results
Number of patients | 505 |
Age (years)a
| 61 (32; 93) |
Paritya
| 2 (0; 8) |
Body mass index (kg/m2)a
| 26 (17; 42) |
Postmenopausal statusb
| 428 (88.1%) |
Hormone replacement therapyb
| 32 (6.5%) |
Previous urogynaecological surgery | |
Anterior compartmentc
| 184 (36.4%) |
Posterior compartmentc
| 174 (34.4%) |
Central compartmentd
| 308 (64.0%) |
Incontinence surgerye
| 66 (16.0%) |
Comorbidity | |
Central nervous system disease | 43 (8.5%) |
Cardiovascular disease | 107 (21.2%) |
Respiratory disease | 36 (7.1%) |
Gastrointestinal disease | 47 (9.3%) |
Endocrine disease | 49 (9.7%) |
Musculoskeletal disease | 71 (14.1%) |
Type of surgery | |
Anterior compartment | 321 (63.6%) |
Posterior compartment | 398 (78.8%) |
Central compartment | 98 (19.4%) |
Use of vaginal mesh material | 253 (50.1%) |
Stress incontinence surgery | 21 (4.2%) |
Stage | Preoperativea
| Postoperativeb
|
P
| |
---|---|---|---|---|
Overall | 0 | 0 (0%) | 42 (8.9%) | 0.000 |
1 | 0 (0%) | 195 (41.1%) | ||
2 | 207 (41.0%) | 215 (45.4%) | ||
3 | 283 (56.0%) | 18 (3.8%) | ||
4 | 15 (3.0%) | 4 (0.8%) | ||
Anterior | 0 | 35 (6.9%) | 171 (36.1%) | 0.000 |
1 | 116 (23%) | 139 (29.3%) | ||
2 | 160 (31.7%) | 148 (31.2%) | ||
3 | 180 (35.6%) | 12 (2.5%) | ||
4 | 14 (2.8%) | 4 (0.8%) | ||
Posterior | 0 | 36 (7.1%) | 250 (52.7%) | 0.000 |
1 | 89 (17.6%) | 144 (30.4%) | ||
2 | 232 (45.9%) | 69 (14.6%) | ||
3 | 134 (26.5%) | 7 (1.5%) | ||
4 | 14 (2.8%) | 4 (0.8%) | ||
Centrala
| 0 | 40 (8.2%) | 130 (27.4%) | 0.000 |
1 | 352 (72.6%) | 320 (67.5%) | ||
2 | 32 (6.6%) | 14 (3.0%) | ||
3 | 49 (10.1%) | 6 (1.3%) | ||
4 | 12 (2.5%) | 4 (0.8%) |
Preoperative | Postoperative |
P
a
| ||||
---|---|---|---|---|---|---|
No symptoms or little or no bother | Moderate to severe bother | No symptoms or little or no bother | Moderate to severe bother | |||
De novo | ||||||
Frequency | 320 (63.4%) | 185 (36.6%) | 410 (81.2%) | 74 (14.6%) | 31 (6.1%) | 0.000 |
Urgency | 323 (64.0%) | 182 (36.8%) | 415 (82.2%) | 65 (12.9%) | 25 (5.0%) | 0.000 |
Urge incontinence | 398 (78.8%) | 107 (21.2%) | 447 (88.5%) | 31 (6.1%) | 27 (5.3%) | 0.000 |
Nocturia | 368 (72.9%) | 137 (27.1%) | 421 (83.4%) | 56 (11.1%) | 28 (5.5%) | 0.000 |
Preoperative domain score | Postoperative domain score |
P
a
| |
---|---|---|---|
Overactive bladder | 33.0 (27.1) | 20.8 (23.0) | 0.000 |
Incontinenceb
| 24.9 (26.6) | 19.0 (22.2) | 0.000 |
Obstructive micturitionc
| 28.4 (29.4) | 15.3 (22.4) | 0.000 |
Genital prolapsed
| 51.4 (33.6) | 6.0 (15.6) | 0.000 |
Frequency OR (95% CI) | Urgency OR (95% CI) | Urge incontinence OR (95% CI) | Nocturia OR (95% CI) | ||
---|---|---|---|---|---|
Follow-up (months) | 1.0 (0.91; 1.0) | 1.0 (0.9; 1.0) | 1.0 (0. 9; 1.0)a
| 1.0 (1.0; 1.1) | |
Age (years) | 1.0 (1.0; 1.0) | 1.0 (1.0; 1.0) | 1.0 (1.0; 1.0) | 1.0 (1.0; 1.0)a
| |
Parity | ≤2 | Ref. | Ref. | Ref. | Ref. |
>2 | 0.9 (0.6; 1. 5) | 0.7 (0. 5; 1.2)a
| 0.7 (0.4; 1.2)a
| 1.1 (0.7; 1.7) | |
Body mass index (kg/m2) |
1.1 (1.0; 1.1)
| 1.0 (1.0; 1.1) | 1.0 (1.0; 1.1) | 1.1 (1.0; 1.1)a
| |
Postmenopausal statusb
| Yes | 1.0 (0. 5; 2.0) | 1.4 (0.6; 3.1) | 0.8 (0.4; 1.8) | 1.3 (0.6; 2.8) |
No | Ref. | Ref. | Ref. | Ref. | |
Previous urogynaecological surgery | |||||
Prolapse surgeryc
| Yes | 1.0 (0.7; 1.6) | 1.3 (0.8; 2.0)a
| 1.2 (0.7; 2.1) | 1.4 (0.9; 2.2)a
|
No | Ref. | Ref. | Ref. | Ref. | |
Hysterectomyd
| Yes | 1.3 (0.8; 2.1)a
|
1.9 (1.1; 3.2)
| 1.3 (0.7; 2.4) | 0.9 (0.6; 1.5) |
No | Ref. | Ref. | Ref. | Ref. | |
Incontinence surgerye
| Yes | 1.7 (0.96; 3.1)a
| 1.2 (0.7; 2.3) |
2.1 (1. 1; 4.2)
| 1.4 (0.7; 2.7)a
|
No | Ref. | Ref. | Ref. | Ref. | |
Type of surgery | |||||
Anterior compartment | Yes | 0.7 (0.4; 1.1)a
|
0.5 (0.3; 0.8)
|
0.6 (0.3; 1.0)
| 0.9 (0.6; 1.5) |
No | Ref. | Ref. | Ref. | Ref. | |
Posterior compartment | Yes | 0.9 (0.5; 1.6) | 1.1 (0.6; 1.9) | 1.0 (0.5; 2.0) | 0.6 (0.4; 1.0)a
|
No | Ref. | Ref. | Ref. | Ref. | |
Central compartment | Yes | 0.5 (0.3; 1.1)a
| 0.7 (0.3; 1.2)a
|
0.3 (0.1; 0.8)
| 0.6 (0.3; 1.3)a
|
No | Ref. | Ref. | Ref. | Ref. | |
Concomitant stress incontinence surgery | Yes | 1.4 (0.5; 3.82) | 1.9 (0.7; 5.1)a
| 1.9 (0.6; 5.8)a
| 0.5 (0.1; 2.3) |
No | Ref. | Ref. | Ref. | Ref. | |
Mesh | Yes | 0.9 (0.6; 1.4) |
0.6 (0.4; 0.9)
| 1.2 (0.7; 2.0) | 0.9 (0.6; 1.5) |
No | Ref. | Ref. | Ref. | Ref. | |
Preoperative POP-Q stage | |||||
Anterior | 0/1 | Ref. | Ref. | Ref. | Ref. |
2 | 0.7 (0.4; 1.2) |
0.5 (0.3; 0.9)
| 0.7 (0.4; 1.4) | 0.7 (0.4; 1.3) | |
3/4 |
0.5 (0.3; 0.9)
|
0.3 (0.2; 0.5)
|
0.4 (0.2; 0.9)
| 0.7 (0.4; 1.2) | |
Posterior | 0/1 | Ref. | Ref. | Ref. | Ref. |
2 |
0.6 (0.36; 1.0)
| 0.8 (0.4; 1.4) | 0.6 (0.3; 1.2) | 0.6 (0.3; 1.0) | |
3/4 | 1.1 (0.6; 1.9) | 1.5 (0.8; 2.6) | 1. 3 (0.6; 2.54) | 0.9 (0.5; 1.5) | |
Central | 0/1 | Ref. | Ref. | Ref. | Ref. |
2 | 0.4 (0.1; 1.5) | 1.0 (0.4; 2.6) | 0.2 (0.0; 1.7) | 0.7 (0.2; 2.2) | |
3/4 | 1.1 (0.6; 2.2) | 0. 6 (0.3; 1.3) | 0.6 (0.2; 1.7) | 1.4 (0.7; 2.7) | |
Moderate to severe bother preoperative OAB symptoms | |||||
Frequency | Yes |
9.52 (5.6; 16.1)
|
6.4 (3.8; 10.6)
|
4.6 (2.6; 8.43)
|
3.7 (2.3; 6.1)
|
No | Ref. | Ref. | Ref. | Ref. | |
Urgency | Yes |
6.0 (3.7; 9.8)
|
7.4 (4.4; 12.5)
|
3.9 (2.2; 7.0)
|
2.5 (1.5; 4.0)
|
No | Ref. | Ref. | Ref. | Ref. | |
Urge incontinence | Yes |
4.4 (2.7; 7.15)
|
2.8 (1.7; 4.6)
|
5.5 (3.1; 9.8)
|
2.4 (1.5; 4.1)
|
No | Ref. | Ref. | Ref. | Ref. | |
Nocturia | Yes |
4.4 (2.7; 7.0)
|
3.5 (2.2; 5.6)
|
2.1 (1.2; 3.7)
|
8.45 (5.0; 14.0)
|
No | Ref. | Ref. | Ref. | Ref. | |
Other preoperative micturition symptoms | |||||
Stress incontinence | Yes |
7.9 (4.5; 14.0)
|
6.2 (3.5; 11.0)
|
22.0 (11.5; 42.3)
|
2.4 (1.3; 4.4)
|
No | Ref. | Ref. | Ref. | Ref. | |
Urinary retention | Yes |
16.5 (8.9; 30.8)
|
10.4 (5.7; 18.7)
|
10.2 (5.4; 19.1)
|
7.5 (4.2; 13.5)
|
No | Ref. | Ref. | Ref. | Ref. |
Frequency | Urgency | Urge incontinence | Nocturia | ||
---|---|---|---|---|---|
Follow-up (months) | 0.9 (0.9; 1.0)a
| ||||
Previous urogynaecological surgery | |||||
Hysterectomyb
| Yes | 2.3 (1.2; 4.3) | |||
No | Ref. | ||||
Type of surgery | |||||
Anterior | Yes | 0.5 (0.2; 1.0) | |||
No | Ref. | ||||
Mesh | Yes | 0.4 (0.2; 0.8) | |||
No | Ref. | ||||
Preoperative POP-Q stage | |||||
Anterior | 0/1 | Ref. | Ref. | ||
2 | 0.8 (0.4; 1.5) | 0.5 (0.3; 1.0) | |||
3/4 | 0.4 (0.2; 0.8) | 0.3 (0.2; 0.7) | |||
Posterior | 0/1 | Ref. | |||
2 | 0.5 (0.2; 0.9) | ||||
3/4 | 0.9 (0.4; 1.9) | ||||
Moderate to severe bother preoperative OAB symptoms | |||||
Frequency | Yes | 6.1 (3.3; 11.3) | 2.9 (1.4; 5.9) | 2.8 (1.3; 6.1) | |
No | Ref. | Ref. | Ref. | ||
Urgency | Yes | 4.1 (2.0; 8.4) | |||
No | Ref. | ||||
Urge incontinence | Yes | 2.1 (1.11; 3.7) | 4.1 (1.9; 8.7) | 2.4 (1.2; 4.8) | |
No | Ref. | Ref. | Ref. | ||
Nocturia | Yes | 1.8 (1.0; 3.2) | 7.4 (4.2; 13.2) | ||
No | Ref. | Ref. | |||
Other preoperative micturition symptoms | |||||
Stress incontinence | Yes | 0.4 (0.2; 0.8) | |||
No | Ref. | ||||
Urinary retention | Yes | 2.0 (1.1; 3.6) | |||
No | Ref. | ||||
Variance explained by the modelc
| 32.1% | 31.8% | 21.7% | 26.2% |