Erschienen in:
01.10.2012 | Diagnostic Neuroradiology
Diagnosis of moyamoya disease using 3-T MRI and MRA: value of cisternal moyamoya vessels
verfasst von:
Takeshi Sawada, Akira Yamamoto, Yukio Miki, Ken-ichiro Kikuta, Tomohisa Okada, Mitsunori Kanagaki, Seiko Kasahara, Susumu Miyamoto, Jun C. Takahashi, Hidenao Fukuyama, Kaori Togashi
Erschienen in:
Neuroradiology
|
Ausgabe 10/2012
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Abstract
Introduction
The purpose of this study was to propose new magnetic resonance (MR) criteria of diagnosing moyamoya disease (MMD) from cisternal moyamoya vessels (MMVs) on 3-T magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA) and compare the diagnostic accuracy of the existing MR criteria and the proposed MR criteria.
Methods
Participants comprised 20 consecutive patients with MMD (4 males, 16 females) diagnosed clinically using conventional angiography and 20 controls (13 male and 7 female arteriosclerosis patients). In these participants, 3-T MRI/MRA was evaluated by the existing MR criteria, which use MMVs in the basal ganglia, and the proposed MR criteria, which use cisternal MMVs, and then these two criteria were statistically compared by McNemar’s test.
Results
Diagnostic accuracy was 62.5% with the existing MR criteria and 97.5% with the proposed MR criteria. The proposed MR criteria was more sensitive (1.00) than the existing MR criteria (0.45), but less specific (0.95) than the existing MR criteria (1.00).
Conclusion
The proposed MR criteria using cisternal MMVs showed significantly higher diagnostic accuracy than the existing MR criteria. We believe that our proposed MR criteria will be beneficial for diagnosing MMD.