Erschienen in:
01.10.2012 | Interventional Neuroradiology
Italian multicenter experience with flow-diverter devices for intracranial unruptured aneurysm treatment with periprocedural complications—a retrospective data analysis
verfasst von:
Francesco Briganti, Manuela Napoli, Fabio Tortora, Domenico Solari, Mauro Bergui, Edoardo Boccardi, Enrico Cagliari, Lucio Castellan, Francesco Causin, Elisa Ciceri, Luigi Cirillo, Roberto De Blasi, Luigi Delehaye, Francesco Di Paola, Andrea Fontana, Roberto Gasparotti, Giulio Guidetti, Ignazio Divenuto, Giuseppe Iannucci, Maurizio Isalberti, Marco Leonardi, Fernando Lupo, Salvatore Mangiafico, Andrea Manto, Roberto Menozzi, Mario Muto, Nunzio Paolo Nuzzi, Rosario Papa, Benedetto Petralia, Mariangela Piano, Maurizio Resta, Riccardo Padolecchia, Andrea Saletti, Giovanni Sirabella, Luca Piero Valvassori Bolgè
Erschienen in:
Neuroradiology
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Ausgabe 10/2012
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Abstract
Introduction
We report the experiences of 25 Italian centers, analyzing intra- and periprocedural complications of endovascular treatment of intracranial aneurysms using Silk (Balt Extrusion, Montmorency, France) and pipeline embolization devices (EV3 Inc, Irvine California).
Methods
Two hundred seventy-three patients with 295 cerebral aneurysms, enrolled in 25 centers in Italy and treated with the new flow-diverter devices, were evaluated; 142 patients were treated with Silk and 130 with pipeline (in one case, both devices were used). In 14 (5.2 %) cases devices were used with coils. Aneurysm size was >15 mm in 46.9 %, 5–15 mm in 42.2 %, and <5 mm in 10.8 %. Aneurysm locations were supraclinoid internal carotid artery (ICA) in 163 cases (55.2 %), cavernous ICA in 76 (25.7 %), middle cerebral artery in 11 (3.7 %), PCoA in 6 (2 %), and ACoA in 2 (0.7 %); the vertebrobasilar system accounted for 32 cases (10.8 %) and PCA in 5 (1.7 %).
Results
Technical adverse events occurred with 59 patients (21.6 %); 5 patients died after ischemic events, 10 to hemorrhagic complications, and 1 from external ventricular drain positioning. At 1 month, morbidity and mortality rates were 3.7 % and 5.9 %, respectively
Conclusion
Our retrospective study confirms that morbidity and mortality rates in treatment with FDD of unruptured wide-neck or untreatable cerebral aneurysms do not differ from those reported in the largest series.