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Neuroradiology

Erschienen in:

02.03.2017 | Continuing Education

Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation.

verfasst von: Andrés Server, Nuria Bargalló, Yngvar Fløisand, Jon Sponheim, Francesc Graus, John K. Hald

Erschienen in: Neuroradiology | Ausgabe 2/2017

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Abstract

Neurologic complications are common after hematopoietic stem cell transplantation (HSCT) and solid organ transplantation (SOT) and affect 30–60% of transplant recipients. The aim of this article is to provide a practical imaging approach based on the timeline and etiology of CNS abnormalities, and neurologic complications related to transplantation of specific organs. The lesions will be classified based upon the interval from HSCT procedure: pre-engraftment period <30 days, early post-engraftment period 30–100 days, late post-engraftment period >100 days, and the interval from SOT procedure: postoperative phase 1–4 weeks, early posttransplant syndromes 1–6 months, late posttransplant syndromes >6 months. Further differentiation will be based on etiology: infections, drug toxicity, metabolic derangements, cerebrovascular complications, and posttransplantation malignancies. In addition, differentiation will be based on complications specific to the type of transplantation: allogeneic and autologous hematopoietic stem cells (HSC), heart, lung, kidney, pancreas, and liver. Thus, in this article we emphasize the strategic role of neuroradiology in the diagnosis and response to treatment by utilizing a methodical approach in the work up of patients with neurologic complications after transplantation.

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Titel: Imaging spectrum of central nervous system complications of hematopoietic stem cell and solid organ transplantation.
verfasst von: Andrés Server
Nuria Bargalló
Yngvar Fløisand
Jon Sponheim
Francesc Graus
John K. Hald
Publikationsdatum: 02.03.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Neuroradiology / Ausgabe 2/2017
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-017-1804-4

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