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Erschienen in: Pediatric Radiology 12/2013

01.12.2013 | Original Article

Renal Doppler evaluation in the child with hypertension: a reasonable screening discriminator?

verfasst von: Sumit Chhadia, Richard A. Cohn, Gulsah Vural, James S. Donaldson

Erschienen in: Pediatric Radiology | Ausgabe 12/2013

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Abstract

Background

Hypertension is diagnosed in 1–5% of children, and 5–10% of those hypertensive children have renovascular disease. The gold standard for a diagnosis of renal artery stenosis is arteriography, and Doppler ultrasound (Doppler US) continues to be advocated as a useful screening test.

Objective

The purpose of this study was to determine the utility of Doppler US in children as a screening tool and to better define clinical features of children in whom arteriography should be performed.

Materials and methods

This retrospective study evaluated the imaging and clinical parameters for all children who had a renal US with Doppler followed by a diagnostic arteriogram for the evaluation of hypertension during a 12-year period at a tertiary children’s hospital. Sixty-two children were included. We evaluated each child’s clinical parameters and placed each child into one of three categories of hypertension: mild, moderate or severe.

Results

Eleven of 17 kidneys with proven renal artery stenosis were detected with Doppler US (sensitivity 64%). Six children with renal artery stenosis were missed by Doppler US, four of whom had segmental artery lesions. Of the children with positive renal artery stenosis on arteriography, all but three (79%) were classified as having moderate to severe hypertension.

Conclusion

Doppler US is a useful screening examination when evaluating children with hypertension, detecting renal artery stenosis in most affected children. The clinical risk classifications are helpful in guiding which children should proceed with arteriography regardless of the Doppler US results.
Literatur
1.
Zurück zum Zitat Falkner B (2010) Hypertension in children and adolescents: epidemiology and natural history. Pediatr Nephrol 25:1219–1224PubMedCrossRef Falkner B (2010) Hypertension in children and adolescents: epidemiology and natural history. Pediatr Nephrol 25:1219–1224PubMedCrossRef
2.
Zurück zum Zitat Tullus K, Brennan E, Hamilton G et al (2008) Renovascular hypertension in children. Lancet 371:1453–1463PubMedCrossRef Tullus K, Brennan E, Hamilton G et al (2008) Renovascular hypertension in children. Lancet 371:1453–1463PubMedCrossRef
3.
Zurück zum Zitat Krause I, Cleper R, Kovalski Y et al (2009) Changes in behavior as an early symptom of renovascular hypertension in children. Pediatr Nephrol 24:2271–2274PubMedCrossRef Krause I, Cleper R, Kovalski Y et al (2009) Changes in behavior as an early symptom of renovascular hypertension in children. Pediatr Nephrol 24:2271–2274PubMedCrossRef
4.
Zurück zum Zitat Candel-Pau J, Castilla-Fernández Y, Madrid-Aris A et al (2008) Hypertension and segmental renal infarction in children: apropos of two cases. Pediatr Nephrol 23:841–845PubMedCrossRef Candel-Pau J, Castilla-Fernández Y, Madrid-Aris A et al (2008) Hypertension and segmental renal infarction in children: apropos of two cases. Pediatr Nephrol 23:841–845PubMedCrossRef
5.
Zurück zum Zitat Drelich-Zbroja A, Jargiello T, Drelich G et al (2004) Renal artery stenosis: value of contrast enhanced ultrasonography. Abdom Imaging 29:518–524PubMedCrossRef Drelich-Zbroja A, Jargiello T, Drelich G et al (2004) Renal artery stenosis: value of contrast enhanced ultrasonography. Abdom Imaging 29:518–524PubMedCrossRef
6.
Zurück zum Zitat Williams GJ, Macaskill P, Chan SF et al (2007) Comparative accuracy of renal duplex sonographic parameters in the diagnosis of renal artery stenosis: paired and unpaired analysis. AJR Am J Roentgenol 188:798–811PubMedCrossRef Williams GJ, Macaskill P, Chan SF et al (2007) Comparative accuracy of renal duplex sonographic parameters in the diagnosis of renal artery stenosis: paired and unpaired analysis. AJR Am J Roentgenol 188:798–811PubMedCrossRef
7.
Zurück zum Zitat Solar M, Zizka J, Krajina A et al (2011) Comparison of duplex ultrasonography and magnetic resonance imaging in the detection of significant renal artery stenosis. Acta Medica (Hradec Kralove) 54:9–12 Solar M, Zizka J, Krajina A et al (2011) Comparison of duplex ultrasonography and magnetic resonance imaging in the detection of significant renal artery stenosis. Acta Medica (Hradec Kralove) 54:9–12
8.
Zurück zum Zitat Johansson M, Jensen G, Aurell M et al (2000) Evaluation of duplex ultrasound and captopril renography for detection of renovascular hypertension. Kidney Int 58:774–782PubMedCrossRef Johansson M, Jensen G, Aurell M et al (2000) Evaluation of duplex ultrasound and captopril renography for detection of renovascular hypertension. Kidney Int 58:774–782PubMedCrossRef
9.
Zurück zum Zitat Voiculescu A, Hofer M, Hetzel GR et al (2001) Noninvasive investigation for renal artery stenosis: contrast-enhanced magnetic resonance angiography and color Doppler sonography as compared to digital subtraction angiography. Clin Exper Hypertens 23:521–531CrossRef Voiculescu A, Hofer M, Hetzel GR et al (2001) Noninvasive investigation for renal artery stenosis: contrast-enhanced magnetic resonance angiography and color Doppler sonography as compared to digital subtraction angiography. Clin Exper Hypertens 23:521–531CrossRef
10.
Zurück zum Zitat Rountas C, Vlychou M, Vassiou K et al (2007) Imaging modalities for renal artery stenosis in suspected renovascular hypertension: prospective intraindividual comparison of color Doppler US, CT angiography, GD-enhanced MR angiography, and digital subtraction angiography. Ren Fail 29:295–302PubMedCrossRef Rountas C, Vlychou M, Vassiou K et al (2007) Imaging modalities for renal artery stenosis in suspected renovascular hypertension: prospective intraindividual comparison of color Doppler US, CT angiography, GD-enhanced MR angiography, and digital subtraction angiography. Ren Fail 29:295–302PubMedCrossRef
11.
Zurück zum Zitat Tullus K, Roebuck DJ, McLaren CA et al (2010) Imaging in the evaluation of renovascular disease. Pediatr Nephrol 25:1049–1056PubMedCrossRef Tullus K, Roebuck DJ, McLaren CA et al (2010) Imaging in the evaluation of renovascular disease. Pediatr Nephrol 25:1049–1056PubMedCrossRef
12.
Zurück zum Zitat Seong CK, Kim SH, Sim JS (2001) Detection of segmental branch renal artery stenosis by Doppler US: a case report. Korean J Radiol 2:57–60PubMedCrossRef Seong CK, Kim SH, Sim JS (2001) Detection of segmental branch renal artery stenosis by Doppler US: a case report. Korean J Radiol 2:57–60PubMedCrossRef
13.
Zurück zum Zitat Vade A, Agrawal R, Lim-Dunham J et al (2002) Utility of computed tomographic renal angiogram in the management of childhood hypertension. Pediatr Nephrol 17:741–747PubMedCrossRef Vade A, Agrawal R, Lim-Dunham J et al (2002) Utility of computed tomographic renal angiogram in the management of childhood hypertension. Pediatr Nephrol 17:741–747PubMedCrossRef
14.
Zurück zum Zitat Hacklander T, Mertens H, Stattaus J et al (2004) Evaluation of renovascular hypertension: comparison of functional MRI and contrast-enhanced MRA with a routinely performed renal scintigraphy and DSA. J Comput Assist Tomogr 28:823–831PubMedCrossRef Hacklander T, Mertens H, Stattaus J et al (2004) Evaluation of renovascular hypertension: comparison of functional MRI and contrast-enhanced MRA with a routinely performed renal scintigraphy and DSA. J Comput Assist Tomogr 28:823–831PubMedCrossRef
15.
Zurück zum Zitat Deal JE, Snell MF, Barratt TM et al (1992) Renovascular disease in childhood. J Pediatr 121:378–384PubMedCrossRef Deal JE, Snell MF, Barratt TM et al (1992) Renovascular disease in childhood. J Pediatr 121:378–384PubMedCrossRef
16.
Zurück zum Zitat Vo NJ, Hammelman BD, Racadio JM et al (2006) Anatomic distribution of renal artery stenosis in children: implications for imaging. Pediatr Radiol 36:1032–1036PubMedCrossRef Vo NJ, Hammelman BD, Racadio JM et al (2006) Anatomic distribution of renal artery stenosis in children: implications for imaging. Pediatr Radiol 36:1032–1036PubMedCrossRef
17.
Zurück zum Zitat Shahdadpuri J, Frank R, Gauthier BG et al (2000) Yield of renal arteriography in the evaluation of pediatric hypertension. Pediatr Nephrol 14:816–819PubMedCrossRef Shahdadpuri J, Frank R, Gauthier BG et al (2000) Yield of renal arteriography in the evaluation of pediatric hypertension. Pediatr Nephrol 14:816–819PubMedCrossRef
Metadaten
Titel
Renal Doppler evaluation in the child with hypertension: a reasonable screening discriminator?
verfasst von
Sumit Chhadia
Richard A. Cohn
Gulsah Vural
James S. Donaldson
Publikationsdatum
01.12.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 12/2013
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-013-2741-y

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