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Erschienen in: Pediatric Radiology 6/2016

01.05.2016 | Pediatric Body MRI

Strategies to minimize sedation in pediatric body magnetic resonance imaging

verfasst von: Camilo Jaimes, Michael S. Gee

Erschienen in: Pediatric Radiology | Ausgabe 6/2016

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Abstract

The high soft-tissue contrast of MRI and the absence of ionizing radiation make it a valuable tool for assessment of body pathology in children. Infants and young children are often unable to cooperate with awake MRI so sedation or general anesthesia might be required. However, given recent data on the costs and potential risks of anesthesia in young children, there is a need to try to decrease or avoid sedation in this population when possible. Child life specialists in radiology frequently use behavioral techniques and audiovisual support devices, and they practice with children and families using mock scanners to improve child compliance with MRI. Optimization of the MR scanner environment is also important to create a child-friendly space. If the child can remain inside the MRI scanner, a variety of emerging techniques can reduce the effect of involuntary motion. Using sequences with short acquisition times such as single-shot fast spin echo and volumetric gradient echo can decrease artifacts and improve image quality. Breath-holding, respiratory triggering and signal averaging all reduce respiratory motion. Emerging techniques such as radial and multislice k-space acquisition, navigator motion correction, as well as parallel imaging and compressed sensing reconstruction methods can further accelerate acquisition and decrease motion. Collaboration among radiologists, anesthesiologists, technologists, child life specialists and families is crucial for successful performance of MRI in young children.
Literatur
1.
Zurück zum Zitat Karian VE, Burrows PE, Zurakowski D et al (2002) The development of a pediatric radiology sedation program. Pediatr Radiol 32:348–353CrossRefPubMed Karian VE, Burrows PE, Zurakowski D et al (2002) The development of a pediatric radiology sedation program. Pediatr Radiol 32:348–353CrossRefPubMed
2.
Zurück zum Zitat Malviya S, Voepel-Lewis T, Eldevik OP et al (2000) Sedation and general anaesthesia in children undergoing MRI and CT: adverse events and outcomes. Br J Anaesth 84:743–748CrossRefPubMed Malviya S, Voepel-Lewis T, Eldevik OP et al (2000) Sedation and general anaesthesia in children undergoing MRI and CT: adverse events and outcomes. Br J Anaesth 84:743–748CrossRefPubMed
4.
Zurück zum Zitat American Academy of Pediatrics, American Academy of Pediatric Dentristry, Coté CJ et al (2006) Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics 118:2587–2602CrossRef American Academy of Pediatrics, American Academy of Pediatric Dentristry, Coté CJ et al (2006) Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics 118:2587–2602CrossRef
5.
Zurück zum Zitat Khan JJ, Donnelly LF, Koch BL et al (2007) A program to decrease the need for pediatric sedation for CT and MRI. Appl Radiol 36:30–33 Khan JJ, Donnelly LF, Koch BL et al (2007) A program to decrease the need for pediatric sedation for CT and MRI. Appl Radiol 36:30–33
6.
Zurück zum Zitat Arthurs OJ, Sury M (2013) Anaesthesia or sedation for paediatric MRI: advantages and disadvantages. Curr Opin Anaesthesiol 26:489–494CrossRefPubMed Arthurs OJ, Sury M (2013) Anaesthesia or sedation for paediatric MRI: advantages and disadvantages. Curr Opin Anaesthesiol 26:489–494CrossRefPubMed
7.
Zurück zum Zitat Edwards AD, Arthurs OJ (2011) Paediatric MRI under sedation: is it necessary? What is the evidence for the alternatives? Pediatr Radiol 41:1353–1364CrossRefPubMed Edwards AD, Arthurs OJ (2011) Paediatric MRI under sedation: is it necessary? What is the evidence for the alternatives? Pediatr Radiol 41:1353–1364CrossRefPubMed
8.
Zurück zum Zitat Slovis TL (2011) Sedation and anesthesia issues in pediatric imaging. Pediatr Radiol 41:514–516CrossRefPubMed Slovis TL (2011) Sedation and anesthesia issues in pediatric imaging. Pediatr Radiol 41:514–516CrossRefPubMed
9.
Zurück zum Zitat Mason KP, Michna E, DiNardo JA et al (2002) Evolution of a protocol for ketamine-induced sedation as an alternative to general anesthesia for interventional radiologic procedures in pediatric patients. Radiology 225:457–465CrossRefPubMed Mason KP, Michna E, DiNardo JA et al (2002) Evolution of a protocol for ketamine-induced sedation as an alternative to general anesthesia for interventional radiologic procedures in pediatric patients. Radiology 225:457–465CrossRefPubMed
10.
Zurück zum Zitat Sanborn PA, Michna E, Zurakowski D et al (2005) Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology 237:288–294CrossRefPubMed Sanborn PA, Michna E, Zurakowski D et al (2005) Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology 237:288–294CrossRefPubMed
11.
Zurück zum Zitat Creeley C, Dikranian K, Dissen G et al (2013) Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain. Br J Anaesth 110:i29–i38CrossRefPubMedPubMedCentral Creeley C, Dikranian K, Dissen G et al (2013) Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain. Br J Anaesth 110:i29–i38CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Wilder RT, Flick RP, Sprung J et al (2009) Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology 110:796–804CrossRefPubMedPubMedCentral Wilder RT, Flick RP, Sprung J et al (2009) Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology 110:796–804CrossRefPubMedPubMedCentral
13.
Zurück zum Zitat Rappaport BA, Suresh S, Hertz S et al (2015) Anesthetic neurotoxicity — clinical implications of animal models. N Engl J Med 372:796–797CrossRefPubMed Rappaport BA, Suresh S, Hertz S et al (2015) Anesthetic neurotoxicity — clinical implications of animal models. N Engl J Med 372:796–797CrossRefPubMed
14.
Zurück zum Zitat Vanderby SA, Babyn PS, Carter MW et al (2010) Effect of anesthesia and sedation on pediatric MR imaging patient flow. Radiology 256:229–237CrossRefPubMed Vanderby SA, Babyn PS, Carter MW et al (2010) Effect of anesthesia and sedation on pediatric MR imaging patient flow. Radiology 256:229–237CrossRefPubMed
15.
Zurück zum Zitat McGee K (2003) The role of a child life specialist in a pediatric radiology department. Pediatr Radiol 33:467–474CrossRefPubMed McGee K (2003) The role of a child life specialist in a pediatric radiology department. Pediatr Radiol 33:467–474CrossRefPubMed
16.
Zurück zum Zitat Goldberger GL, Wolfer J (1990) Helping children cope with health care procedures. Contemp Pediatr 7:141–162 Goldberger GL, Wolfer J (1990) Helping children cope with health care procedures. Contemp Pediatr 7:141–162
17.
Zurück zum Zitat Durand DJ, Young M, Nagy P et al (2015) Mandatory child life consultation and its impact on pediatric MRI workflow in an academic medical center. J Am Coll Radiol 12:594–598CrossRefPubMed Durand DJ, Young M, Nagy P et al (2015) Mandatory child life consultation and its impact on pediatric MRI workflow in an academic medical center. J Am Coll Radiol 12:594–598CrossRefPubMed
18.
Zurück zum Zitat Carbajal R, Chauvet X, Couderc S et al (1999) Randomised trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates. BMJ 319:1393–1397CrossRefPubMedPubMedCentral Carbajal R, Chauvet X, Couderc S et al (1999) Randomised trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates. BMJ 319:1393–1397CrossRefPubMedPubMedCentral
19.
Zurück zum Zitat Harned RK 2nd, Strain JD (2001) MRI-compatible audio/visual system: impact on pediatric sedation. Pediatr Radiol 31:247–250CrossRefPubMed Harned RK 2nd, Strain JD (2001) MRI-compatible audio/visual system: impact on pediatric sedation. Pediatr Radiol 31:247–250CrossRefPubMed
20.
Zurück zum Zitat Courtier J, Cardenas A, Tan C et al (2015) Non-anesthesia MR enterography in very young children — feasibility, technique and performance. J Pediatr Gastroenterol Nutr 60(6):754–61. doi:10.1097/MPG.0000000000000712 Courtier J, Cardenas A, Tan C et al (2015) Non-anesthesia MR enterography in very young children — feasibility, technique and performance. J Pediatr Gastroenterol Nutr 60(6):754–61. doi:10.​1097/​MPG.​0000000000000712​
21.
Zurück zum Zitat De Bie HM, Boersma M, Wattjes MP et al (2010) Preparing children with a mock scanner training protocol results in high quality structural and functional MRI scans. Eur J Pediatr 169:1079–1085CrossRefPubMedPubMedCentral De Bie HM, Boersma M, Wattjes MP et al (2010) Preparing children with a mock scanner training protocol results in high quality structural and functional MRI scans. Eur J Pediatr 169:1079–1085CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Barnea-Goraly N, Weinzimer SA, Ruedy KJ et al (2014) High success rates of sedation-free brain MRI scanning in young children using simple subject preparation protocols with and without a commercial mock scanner — the Diabetes Research in Children Network (DirecNet) experience. Pediatr Radiol 44:181–186CrossRefPubMedPubMedCentral Barnea-Goraly N, Weinzimer SA, Ruedy KJ et al (2014) High success rates of sedation-free brain MRI scanning in young children using simple subject preparation protocols with and without a commercial mock scanner — the Diabetes Research in Children Network (DirecNet) experience. Pediatr Radiol 44:181–186CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Carter AJ, Greer ML, Gray SE et al (2010) Mock MRI: reducing the need for anaesthesia in children. Pediatr Radiol 40:1368–1374CrossRefPubMed Carter AJ, Greer ML, Gray SE et al (2010) Mock MRI: reducing the need for anaesthesia in children. Pediatr Radiol 40:1368–1374CrossRefPubMed
24.
Zurück zum Zitat Yang RK, Roth CG, Ward RJ et al (2010) Optimizing abdominal MR imaging: approaches to common problems. Radiographics 30:185–199CrossRefPubMed Yang RK, Roth CG, Ward RJ et al (2010) Optimizing abdominal MR imaging: approaches to common problems. Radiographics 30:185–199CrossRefPubMed
25.
Zurück zum Zitat Chavhan GB, Babyn PS, Vasanawala SS (2013) Abdominal MR imaging in children: motion compensation, sequence optimization, and protocol organization. Radiographics 33:703–719CrossRefPubMed Chavhan GB, Babyn PS, Vasanawala SS (2013) Abdominal MR imaging in children: motion compensation, sequence optimization, and protocol organization. Radiographics 33:703–719CrossRefPubMed
26.
27.
Zurück zum Zitat Felmlee JP, Ehman RL (1987) Spatial presaturation: a method for suppressing flow artifacts and improving depiction of vascular anatomy in MR imaging. Radiology 164:559–564CrossRefPubMed Felmlee JP, Ehman RL (1987) Spatial presaturation: a method for suppressing flow artifacts and improving depiction of vascular anatomy in MR imaging. Radiology 164:559–564CrossRefPubMed
28.
Zurück zum Zitat Klessen C, Asbach P, Kroencke TJ et al (2005) Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction. J Magn Reson Imaging 21:576–582CrossRefPubMed Klessen C, Asbach P, Kroencke TJ et al (2005) Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction. J Magn Reson Imaging 21:576–582CrossRefPubMed
29.
Zurück zum Zitat Vasanawala SS, Iwadate Y, Church DG et al (2010) Navigated abdominal T1-W MRI permits free-breathing image acquisition with less motion artifact. Pediatr Radiol 40:340–344CrossRefPubMedPubMedCentral Vasanawala SS, Iwadate Y, Church DG et al (2010) Navigated abdominal T1-W MRI permits free-breathing image acquisition with less motion artifact. Pediatr Radiol 40:340–344CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Wood ML, Runge VM, Henkelman RM (1988) Overcoming motion in abdominal MR imaging. AJR Am J Roentgenol 150:513–522CrossRefPubMed Wood ML, Runge VM, Henkelman RM (1988) Overcoming motion in abdominal MR imaging. AJR Am J Roentgenol 150:513–522CrossRefPubMed
31.
Zurück zum Zitat Epelman M, Dinan D, Gee MS et al (2013) Mullerian duct and related anomalies in children and adolescents. Magn Reson Imaging Clin N Am 21:773–789CrossRefPubMed Epelman M, Dinan D, Gee MS et al (2013) Mullerian duct and related anomalies in children and adolescents. Magn Reson Imaging Clin N Am 21:773–789CrossRefPubMed
32.
Zurück zum Zitat Olpin JD, Heilbrun M (2010) Imaging of Mullerian duct anomalies. Top Magn Reson Imaging 21:225–235CrossRefPubMed Olpin JD, Heilbrun M (2010) Imaging of Mullerian duct anomalies. Top Magn Reson Imaging 21:225–235CrossRefPubMed
33.
Zurück zum Zitat Hennig J, Nauerth A, Friedburg H (1986) RARE imaging: a fast imaging method for clinical MR. Magn Reson Med 3:823–833CrossRefPubMed Hennig J, Nauerth A, Friedburg H (1986) RARE imaging: a fast imaging method for clinical MR. Magn Reson Med 3:823–833CrossRefPubMed
34.
Zurück zum Zitat Katayama M, Masui T, Kobayashi S et al (2001) Fat-suppressed T2-weighted MRI of the liver: comparison of respiratory-triggered fast spin-echo, breath-hold single-shot fast spin-echo, and breath-hold fast-recovery fast spin-echo sequences. J Magn Reson Imaging 14:439–449CrossRefPubMed Katayama M, Masui T, Kobayashi S et al (2001) Fat-suppressed T2-weighted MRI of the liver: comparison of respiratory-triggered fast spin-echo, breath-hold single-shot fast spin-echo, and breath-hold fast-recovery fast spin-echo sequences. J Magn Reson Imaging 14:439–449CrossRefPubMed
35.
Zurück zum Zitat Dutka MV, Bergin D, O’Kane PL et al (2008) Rapid multiplanar abdominal survey using MRI with the steady-state free-precession technique. J Magn Reson Imaging 27:198–203CrossRefPubMed Dutka MV, Bergin D, O’Kane PL et al (2008) Rapid multiplanar abdominal survey using MRI with the steady-state free-precession technique. J Magn Reson Imaging 27:198–203CrossRefPubMed
36.
Zurück zum Zitat Malamateniou C, Malik SJ, Counsell SJ et al (2013) Motion-compensation techniques in neonatal and fetal MR imaging. AJNR Am J Neuroradiol 34:1124–1136CrossRefPubMed Malamateniou C, Malik SJ, Counsell SJ et al (2013) Motion-compensation techniques in neonatal and fetal MR imaging. AJNR Am J Neuroradiol 34:1124–1136CrossRefPubMed
37.
Zurück zum Zitat Pipe JG (1999) Motion correction with PROPELLER MRI: application to head motion and free-breathing cardiac imaging. Magn Reson Med 42:963–969CrossRefPubMed Pipe JG (1999) Motion correction with PROPELLER MRI: application to head motion and free-breathing cardiac imaging. Magn Reson Med 42:963–969CrossRefPubMed
38.
Zurück zum Zitat Forbes KP, Pipe JG, Bird CR et al (2001) PROPELLER MRI: clinical testing of a novel technique for quantification and compensation of head motion. J Magn Reson Imaging 14:215–222CrossRefPubMed Forbes KP, Pipe JG, Bird CR et al (2001) PROPELLER MRI: clinical testing of a novel technique for quantification and compensation of head motion. J Magn Reson Imaging 14:215–222CrossRefPubMed
39.
Zurück zum Zitat Darge K, Anupindi SA, Jaramillo D (2011) MR imaging of the abdomen and pelvis in infants, children, and adolescents. Radiology 261:12–29CrossRefPubMed Darge K, Anupindi SA, Jaramillo D (2011) MR imaging of the abdomen and pelvis in infants, children, and adolescents. Radiology 261:12–29CrossRefPubMed
40.
Zurück zum Zitat Hirokawa Y, Isoda H, Maetani YS et al (2008) MRI artifact reduction and quality improvement in the upper abdomen with PROPELLER and prospective acquisition correction (PACE) technique. AJR Am J Roentgenol 191:1154–1158CrossRefPubMed Hirokawa Y, Isoda H, Maetani YS et al (2008) MRI artifact reduction and quality improvement in the upper abdomen with PROPELLER and prospective acquisition correction (PACE) technique. AJR Am J Roentgenol 191:1154–1158CrossRefPubMed
41.
Zurück zum Zitat Chandarana H, Block TK, Rosenkrantz AB et al (2011) Free-breathing radial 3D fat-suppressed T1-weighted gradient echo sequence: a viable alternative for contrast-enhanced liver imaging in patients unable to suspend respiration. Invest Radiol 46:648–653CrossRefPubMed Chandarana H, Block TK, Rosenkrantz AB et al (2011) Free-breathing radial 3D fat-suppressed T1-weighted gradient echo sequence: a viable alternative for contrast-enhanced liver imaging in patients unable to suspend respiration. Invest Radiol 46:648–653CrossRefPubMed
42.
Zurück zum Zitat Glockner JF, Hu HH, Stanley DW et al (2005) Parallel MR imaging: a user’s guide. Radiographics 25:1279–1297CrossRefPubMed Glockner JF, Hu HH, Stanley DW et al (2005) Parallel MR imaging: a user’s guide. Radiographics 25:1279–1297CrossRefPubMed
44.
Zurück zum Zitat Breuer FA, Blaimer M, Heidemann RM et al (2005) Controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) for multi-slice imaging. Magn Reson Med 53:684–691CrossRefPubMed Breuer FA, Blaimer M, Heidemann RM et al (2005) Controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) for multi-slice imaging. Magn Reson Med 53:684–691CrossRefPubMed
45.
47.
Zurück zum Zitat Obele CC, Glielmi C, Ream J et al (2015) Simultaneous multislice accelerated free-breathing diffusion-weighted imaging of the liver at 3 T. Abdom Imaging 40:2323–2330CrossRefPubMed Obele CC, Glielmi C, Ream J et al (2015) Simultaneous multislice accelerated free-breathing diffusion-weighted imaging of the liver at 3 T. Abdom Imaging 40:2323–2330CrossRefPubMed
49.
Zurück zum Zitat Zhang T, Chowdhury S, Lustig M et al (2014) Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction. J Magn Reson Imaging 40:13–25CrossRefPubMedPubMedCentral Zhang T, Chowdhury S, Lustig M et al (2014) Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction. J Magn Reson Imaging 40:13–25CrossRefPubMedPubMedCentral
50.
Zurück zum Zitat Cheng JY, Zhang T, Ruangwattanapaisarn N et al (2015) Free-breathing pediatric MRI with nonrigid motion correction and acceleration. J Magn Reson Imaging 42:407–420CrossRefPubMed Cheng JY, Zhang T, Ruangwattanapaisarn N et al (2015) Free-breathing pediatric MRI with nonrigid motion correction and acceleration. J Magn Reson Imaging 42:407–420CrossRefPubMed
51.
Zurück zum Zitat McDonald RJ, McDonald JS, Kallmes DF et al (2015) Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology 275:772–782CrossRefPubMed McDonald RJ, McDonald JS, Kallmes DF et al (2015) Intracranial gadolinium deposition after contrast-enhanced MR imaging. Radiology 275:772–782CrossRefPubMed
52.
Zurück zum Zitat Sadowski EA, Bennett LK, Chan MR et al (2007) Nephrogenic systemic fibrosis: risk factors and incidence estimation. Radiology 243:148–157CrossRefPubMed Sadowski EA, Bennett LK, Chan MR et al (2007) Nephrogenic systemic fibrosis: risk factors and incidence estimation. Radiology 243:148–157CrossRefPubMed
53.
Zurück zum Zitat Ramalho M, Heredia V, de Campos RO et al (2012) In-phase and out-of-phase gradient-echo imaging in abdominal studies: intra-individual comparison of three different techniques. Acta Radiol 53:441–449CrossRefPubMed Ramalho M, Heredia V, de Campos RO et al (2012) In-phase and out-of-phase gradient-echo imaging in abdominal studies: intra-individual comparison of three different techniques. Acta Radiol 53:441–449CrossRefPubMed
54.
Zurück zum Zitat Mitchell CL, Vasanawala SS (2011) An approach to pediatric liver MRI. AJR Am J Roentgenol 196:W519–W526CrossRefPubMed Mitchell CL, Vasanawala SS (2011) An approach to pediatric liver MRI. AJR Am J Roentgenol 196:W519–W526CrossRefPubMed
Metadaten
Titel
Strategies to minimize sedation in pediatric body magnetic resonance imaging
verfasst von
Camilo Jaimes
Michael S. Gee
Publikationsdatum
01.05.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Radiology / Ausgabe 6/2016
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-016-3613-z

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