Skip to main content
Erschienen in: Abdominal Radiology 4/2011

01.08.2011

Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT)

verfasst von: Katherine Cameron, Sivan Golan, William Simpson, Steven Peti, Sasan Roayaie, Daniel Labow, Lale Kostakoglu

Erschienen in: Abdominal Radiology | Ausgabe 4/2011

Einloggen, um Zugang zu erhalten

Abstract

Although the current literature is limited, available data suggest that 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) imaging improves the evaluation of patients with recurrent pancreatic carcinoma and cholangiocarcinoma. There is evidence that PET/CT is particularly useful in the setting of elevated tumor markers and negative or equivocal CT findings. This article reviews the nature of these carcinomas in the post-therapy setting and describes the strengths and limitations of PET/CT when used for monitoring recurrence.
Literatur
1.
2.
Zurück zum Zitat American Gastroenterological Association medical position statement: epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. Gastroenterology 117:1463–1484 (1999) American Gastroenterological Association medical position statement: epidemiology, diagnosis, and treatment of pancreatic ductal adenocarcinoma. Gastroenterology 117:1463–1484 (1999)
3.
Zurück zum Zitat West J, Wood H, Logan RF, Quinn M, Aithal GP (2006) Trends in the incidence of primary liver and biliary tract cancers in England and Wales 1971–2001. Br J Cancer 94(11):1751–1758PubMedCrossRef West J, Wood H, Logan RF, Quinn M, Aithal GP (2006) Trends in the incidence of primary liver and biliary tract cancers in England and Wales 1971–2001. Br J Cancer 94(11):1751–1758PubMedCrossRef
4.
Zurück zum Zitat Khan SA, Taylor-Robinson SD, Toledano MB, Elliott Beck A, Thomas HC P (2002) Changing international trends in mortality rates for liver, biliary and pancreatic tumors. J Hepatol 37(6):806–813PubMedCrossRef Khan SA, Taylor-Robinson SD, Toledano MB, Elliott Beck A, Thomas HC P (2002) Changing international trends in mortality rates for liver, biliary and pancreatic tumors. J Hepatol 37(6):806–813PubMedCrossRef
5.
Zurück zum Zitat Patel T (2002) Worldwide trends in mortality from biliary tract malignancies. BMC Cancer 3(2):10CrossRef Patel T (2002) Worldwide trends in mortality from biliary tract malignancies. BMC Cancer 3(2):10CrossRef
6.
Zurück zum Zitat Nehls O, Gregor M, Klump B (2004) Serum and bile markers for cholangiocarcinoma. Semin Liver Dis 24(2):139–154PubMedCrossRef Nehls O, Gregor M, Klump B (2004) Serum and bile markers for cholangiocarcinoma. Semin Liver Dis 24(2):139–154PubMedCrossRef
7.
Zurück zum Zitat National Comprehensive Cancer Network (2008) Clinical practice guidelines in oncology, Hepatobiliary cancers. Version 2 National Comprehensive Cancer Network (2008) Clinical practice guidelines in oncology, Hepatobiliary cancers. Version 2
8.
Zurück zum Zitat Huang QJ, Xu Q, Wang XN, et al. (2002) Spiral multi-phase CT in evaluating resectability of pancreatic carcinoma. Hepatobiliary Pancreat Dis Int 1(4):614–619PubMed Huang QJ, Xu Q, Wang XN, et al. (2002) Spiral multi-phase CT in evaluating resectability of pancreatic carcinoma. Hepatobiliary Pancreat Dis Int 1(4):614–619PubMed
9.
Zurück zum Zitat Tamm EP, Loyer EM, Faria S, et al. (2006) Staging of pancreatic cancer with multidetector CT in the setting of preoperative chemoradiation therapy. Abdom Imaging 31(5):568–574 Tamm EP, Loyer EM, Faria S, et al. (2006) Staging of pancreatic cancer with multidetector CT in the setting of preoperative chemoradiation therapy. Abdom Imaging 31(5):568–574
10.
Zurück zum Zitat Diehl SJ, Lehmann KJ, Sadick M, et al. (1998) Pancreatic cancer: value of dual-phase helical CT in assessing resectability. Radiology 206:373–378PubMed Diehl SJ, Lehmann KJ, Sadick M, et al. (1998) Pancreatic cancer: value of dual-phase helical CT in assessing resectability. Radiology 206:373–378PubMed
11.
Zurück zum Zitat McCarthy MJ, Evans J, Sagar G, et al. (1998) Prediction of resectability of pancreatic malignancy by computed tomography. Br J Surg 85:320–325PubMedCrossRef McCarthy MJ, Evans J, Sagar G, et al. (1998) Prediction of resectability of pancreatic malignancy by computed tomography. Br J Surg 85:320–325PubMedCrossRef
12.
Zurück zum Zitat Ohtani T, Shirai Y, Tsukada K, et al. (1993) Carcinoma of the gallbladder: CT evaluation of lymphatic spread. Radiology 189:875–880PubMed Ohtani T, Shirai Y, Tsukada K, et al. (1993) Carcinoma of the gallbladder: CT evaluation of lymphatic spread. Radiology 189:875–880PubMed
13.
Zurück zum Zitat Ward EM, Stephens DH, Sheedy PF (1983) Computed tomographic characteristics of pancreatic carcinoma: an analysis of 100 cases. Radiographics 3:547–565. Ward EM, Stephens DH, Sheedy PF (1983) Computed tomographic characteristics of pancreatic carcinoma: an analysis of 100 cases. Radiographics 3:547–565.
14.
Zurück zum Zitat Solomon R (2009) Contrast-induced acute kidney injury (CIAKI). Radiol Clin North Am 47(5):783–788PubMedCrossRef Solomon R (2009) Contrast-induced acute kidney injury (CIAKI). Radiol Clin North Am 47(5):783–788PubMedCrossRef
15.
Zurück zum Zitat Sperti C, Pasquali C, Bissoli S, et al. (2010) Tumor relapse after pancreatic cancer resection is detected earlier by 18-FDG PET than by CT. J Gastrointest Surg 14(1):131–140PubMedCrossRef Sperti C, Pasquali C, Bissoli S, et al. (2010) Tumor relapse after pancreatic cancer resection is detected earlier by 18-FDG PET than by CT. J Gastrointest Surg 14(1):131–140PubMedCrossRef
16.
Zurück zum Zitat Casneuf V, Delrue L, Kelles A, et al. (2007) Is combined 18F-flurodeoxyglucose-positron emission tomography/computed tomography superior to positron emission tomography or computed tomography alone for diagnosis, staging and restaging of pancreatic lesions? Acta Gastroenterol Belg 70(4):331–338PubMed Casneuf V, Delrue L, Kelles A, et al. (2007) Is combined 18F-flurodeoxyglucose-positron emission tomography/computed tomography superior to positron emission tomography or computed tomography alone for diagnosis, staging and restaging of pancreatic lesions? Acta Gastroenterol Belg 70(4):331–338PubMed
17.
Zurück zum Zitat Ruf J, Lopez Hanninen E, Oettle H, et al. (2005) Detection of recurrent pancreatic cancer: comparison of FDG-PET with CT/MRI. Pancreatology 5(2–3):266–272PubMedCrossRef Ruf J, Lopez Hanninen E, Oettle H, et al. (2005) Detection of recurrent pancreatic cancer: comparison of FDG-PET with CT/MRI. Pancreatology 5(2–3):266–272PubMedCrossRef
18.
Zurück zum Zitat Rose DM, Delbeke D, Beauchamp RD, et al. (1998) 18-Fluorodeoxyglucose-positron emission tomography (18FDG-PET) in the management of patients with suspected pancreatic cancer. Ann Surg 229:729–738CrossRef Rose DM, Delbeke D, Beauchamp RD, et al. (1998) 18-Fluorodeoxyglucose-positron emission tomography (18FDG-PET) in the management of patients with suspected pancreatic cancer. Ann Surg 229:729–738CrossRef
19.
Zurück zum Zitat Franke C, Klapdor R, Meyerhoff K, Schauman M (1999) 18-F Positron emission tomography of the pancreas: diagnostic benefit in the follow-up of pancreatic carcinoma. Anticancer Res 19:2437–2442PubMed Franke C, Klapdor R, Meyerhoff K, Schauman M (1999) 18-F Positron emission tomography of the pancreas: diagnostic benefit in the follow-up of pancreatic carcinoma. Anticancer Res 19:2437–2442PubMed
20.
Zurück zum Zitat Jadvar H, Fischman AJ (2001) Evaluation of pancreatic carcinoma with FDG PET. Abdom Imaging 26(3):254–259PubMedCrossRef Jadvar H, Fischman AJ (2001) Evaluation of pancreatic carcinoma with FDG PET. Abdom Imaging 26(3):254–259PubMedCrossRef
21.
Zurück zum Zitat Kim J, Quon A, Humke E, Ford JM, Koong AC (2009) Detection of solitary humeral metastasis from pancreatic adenocarcinoma with F-18 FDG PET/CT. Clin Nucl Med 34(5):312–313PubMedCrossRef Kim J, Quon A, Humke E, Ford JM, Koong AC (2009) Detection of solitary humeral metastasis from pancreatic adenocarcinoma with F-18 FDG PET/CT. Clin Nucl Med 34(5):312–313PubMedCrossRef
22.
Zurück zum Zitat Corvera CU, Blumgart LH, Akhurst T, et al. (2008) 18F-fluorodeoxyglucose positron emission tomography influences management decisions in patients with biliary cancer. J Am Coll Surg 206:57–65PubMedCrossRef Corvera CU, Blumgart LH, Akhurst T, et al. (2008) 18F-fluorodeoxyglucose positron emission tomography influences management decisions in patients with biliary cancer. J Am Coll Surg 206:57–65PubMedCrossRef
23.
Zurück zum Zitat Jadvar H, Henderson RW, Conti PS (2007) (18F) fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma. J Comput Assist Tomogr 31:223–228PubMedCrossRef Jadvar H, Henderson RW, Conti PS (2007) (18F) fluorodeoxyglucose positron emission tomography and positron emission tomography: computed tomography in recurrent and metastatic cholangiocarcinoma. J Comput Assist Tomogr 31:223–228PubMedCrossRef
24.
Zurück zum Zitat Peters PE, Beyer K (1985) Normal lymph node cross-sections in different anatomic regions and their significance for computed tomographic diagnosis. Radiologe 25:193–198PubMed Peters PE, Beyer K (1985) Normal lymph node cross-sections in different anatomic regions and their significance for computed tomographic diagnosis. Radiologe 25:193–198PubMed
25.
Zurück zum Zitat Dorfman RE, Alpern MB, Gross BH, Sandler MA (1991) Upper abdominal lymph nodes: criteria for normal size determined with CT. Radiology 180:319–322PubMed Dorfman RE, Alpern MB, Gross BH, Sandler MA (1991) Upper abdominal lymph nodes: criteria for normal size determined with CT. Radiology 180:319–322PubMed
26.
Zurück zum Zitat Lucey BC, Stuhlfaut JW, Soto JA (2005) Mesenteric lymph nodes: detection and significance on MDCT. Am J Roentgenol 184:41–44 Lucey BC, Stuhlfaut JW, Soto JA (2005) Mesenteric lymph nodes: detection and significance on MDCT. Am J Roentgenol 184:41–44
27.
Zurück zum Zitat Pansky B (1990) Anatomy of the pancreas. Emphasis on blood supply and lymphatic drainage. Int J Pancreatol. 7(1–3):101–108 Pansky B (1990) Anatomy of the pancreas. Emphasis on blood supply and lymphatic drainage. Int J Pancreatol. 7(1–3):101–108
28.
Zurück zum Zitat Donatini B, Hidden G (1992) Routes of lymphatic drainage from the pancreas: a suggested segmentation. Surg Radiol Anat 14(1):35–42PubMedCrossRef Donatini B, Hidden G (1992) Routes of lymphatic drainage from the pancreas: a suggested segmentation. Surg Radiol Anat 14(1):35–42PubMedCrossRef
29.
Zurück zum Zitat Weber SM, Jarnagin WR, Klimstra D, et al. (2001) Intrahepatic cholangiocarcinoma: resectability, recurrence pattern, and outcomes. J Am Coll Surg 193(4):384–391PubMedCrossRef Weber SM, Jarnagin WR, Klimstra D, et al. (2001) Intrahepatic cholangiocarcinoma: resectability, recurrence pattern, and outcomes. J Am Coll Surg 193(4):384–391PubMedCrossRef
30.
Zurück zum Zitat Yamamoto M, Takasaki K, Otsubo T, Katsuragawa H, Katagiri S (2001) Recurrence after surgical resection of intrahepatic cholangiocarcinoma. J Hepatobiliary Pancreat Surg 8(2):154–157PubMedCrossRef Yamamoto M, Takasaki K, Otsubo T, Katsuragawa H, Katagiri S (2001) Recurrence after surgical resection of intrahepatic cholangiocarcinoma. J Hepatobiliary Pancreat Surg 8(2):154–157PubMedCrossRef
32.
Zurück zum Zitat Diederichs CG, Staib L, Vogel J, et al. (2000) Values, limitations of 18F-fluorodeoxyglucose-positron-emission tomography with preoperative evaluation of patients with pancreatic masses. Pancreas 20:109PubMedCrossRef Diederichs CG, Staib L, Vogel J, et al. (2000) Values, limitations of 18F-fluorodeoxyglucose-positron-emission tomography with preoperative evaluation of patients with pancreatic masses. Pancreas 20:109PubMedCrossRef
33.
Zurück zum Zitat Shreve PD (1998) Focal fluorine-18 fluorodeoxyglucose accumulation in inflammatory pancreatic disease. Eur J Nucl Med 25:259–264PubMedCrossRef Shreve PD (1998) Focal fluorine-18 fluorodeoxyglucose accumulation in inflammatory pancreatic disease. Eur J Nucl Med 25:259–264PubMedCrossRef
34.
Zurück zum Zitat Diederichs CG, Staib L, Glasbrenner B, et al. (1999) F-18 Fluorodeoxyglucose (FDG) and C-reactive protein (CRP). Clin Pos Imaging 2:131–136CrossRef Diederichs CG, Staib L, Glasbrenner B, et al. (1999) F-18 Fluorodeoxyglucose (FDG) and C-reactive protein (CRP). Clin Pos Imaging 2:131–136CrossRef
35.
Zurück zum Zitat Fritscher-Ravens A, Bohuslavizki KH, Broering DC, et al. (2001) FDG PET in the diagnosis of hilar cholangiocarcinoma. Nucl Med Commun 22:1277–1285PubMedCrossRef Fritscher-Ravens A, Bohuslavizki KH, Broering DC, et al. (2001) FDG PET in the diagnosis of hilar cholangiocarcinoma. Nucl Med Commun 22:1277–1285PubMedCrossRef
36.
Zurück zum Zitat Kim YJ, Yun M, Lee WJ, Kim KS, Lee JD (2003) Usefulness of 18F-FDG PET in intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging 30(11):1467–1472PubMedCrossRef Kim YJ, Yun M, Lee WJ, Kim KS, Lee JD (2003) Usefulness of 18F-FDG PET in intrahepatic cholangiocarcinoma. Eur J Nucl Med Mol Imaging 30(11):1467–1472PubMedCrossRef
37.
Zurück zum Zitat Anderson CD, Rice MH, Pinson CW, et al. (2004) Fluorodeoxyglucose PET imaging in the evaluation of gallbladder carcinoma and cholangiocarcinoma. Gastrointest Surg 8(1):90–97CrossRef Anderson CD, Rice MH, Pinson CW, et al. (2004) Fluorodeoxyglucose PET imaging in the evaluation of gallbladder carcinoma and cholangiocarcinoma. Gastrointest Surg 8(1):90–97CrossRef
38.
Zurück zum Zitat Li TR, Tian JH, Wang H, Chen ZQ, Zhao CL F (2009) Pitfalls in positron emission tomography/computed tomography imaging: causes and their classifications. Chin Med Sci J 24(1):12–19PubMedCrossRef Li TR, Tian JH, Wang H, Chen ZQ, Zhao CL F (2009) Pitfalls in positron emission tomography/computed tomography imaging: causes and their classifications. Chin Med Sci J 24(1):12–19PubMedCrossRef
39.
Zurück zum Zitat Zimny M, Bares R, Fass J, et al. (1997) Fluorine-18 fluorodeoxyglucose positron emission tomography in the differential diagnosis of pancreatic carcinoma: a report of 106 cases. Eur J Nucl Med 24:678–682PubMed Zimny M, Bares R, Fass J, et al. (1997) Fluorine-18 fluorodeoxyglucose positron emission tomography in the differential diagnosis of pancreatic carcinoma: a report of 106 cases. Eur J Nucl Med 24:678–682PubMed
40.
Zurück zum Zitat Kostakoglu L, Hardoff R, Mirtcheva R, Goldsmith SJ (2004) PET-CT fusion imaging in differentiating physiologic from pathologic FDG uptake. Radiographics 24(5):1411–1431PubMedCrossRef Kostakoglu L, Hardoff R, Mirtcheva R, Goldsmith SJ (2004) PET-CT fusion imaging in differentiating physiologic from pathologic FDG uptake. Radiographics 24(5):1411–1431PubMedCrossRef
Metadaten
Titel
Recurrent pancreatic carcinoma and cholangiocarcinoma: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT)
verfasst von
Katherine Cameron
Sivan Golan
William Simpson
Steven Peti
Sasan Roayaie
Daniel Labow
Lale Kostakoglu
Publikationsdatum
01.08.2011
Verlag
Springer-Verlag
Erschienen in
Abdominal Radiology / Ausgabe 4/2011
Print ISSN: 2366-004X
Elektronische ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-011-9729-6

Weitere Artikel der Ausgabe 4/2011

Abdominal Radiology 4/2011 Zur Ausgabe

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.