Erschienen in:
01.01.2015
Alveolar echinococcosis: correlation between hepatic MRI findings and FDG-PET/CT metabolic activity
verfasst von:
Amel Azizi, Oleg Blagosklonov, Ahmed Lounis, Louis Berthet, Dominique-Angèle Vuitton, Solange Bresson-Hadni, Eric Delabrousse
Erschienen in:
Abdominal Radiology
|
Ausgabe 1/2015
Einloggen, um Zugang zu erhalten
Abstract
Objective
To correlate the appearance of alveolar echinococcosis (AE) hepatic lesions in magnetic resonance imaging (MRI) as defined by Kodama, to the metabolic activity visualized in 18-fluoro-deoxyglucose positron emission tomography combined with computed tomography (PET/CT).
Materials and methods
Forty-two patients diagnosed with AE and who underwent both MRI and PET/CT were included. The forty-two hepatic lesions were divided into five types according to Kodama’s classification by three independent readers blinded with regard to the PET/CT information. Concerning PET/CT, two independent readers, unaware of the MRI information, considered the results as positive when an increased FDG-uptake was observed at 1 or 3 h after FDG-injection, and as negative when no increased uptake was noted. Inter-observer agreement was assessed by using κ statistics.
Results
Forty-two lesions were counted and the mean diameter of overall evaluated lesions was 6.3 cm. One lesion (2.4%) was categorized as type 1, 11 (26.2%) as type 2, 24 (57.1%) as type 3, 3 (7.1%) as type 4, and 3 (7.1%) as type 5. The inter-observer analysis found a κ coefficient of 0.96. All type-1, 90.9% of type-2 and 87.5% of type-3 lesions showed an increased FDG-uptake on PET/CT images. All non-microcystic AE liver lesions (types 4 and 5) showed no abnormal increased FDG-uptake on PET/CT images. The inter-observer analysis at 1 and 3 h found a κ coefficient of 0.95 and 0.92, respectively.
Conclusions
In patients with AE liver lesions, the absence of microcysts on MRI is strongly correlated to a metabolically inactive disease.